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The map label for this gene is dcp [H]

Identifier: 108758552

GI number: 108758552

Start: 2654645

End: 2656858

Strand: Direct

Name: dcp [H]

Synonym: MXAN_2286

Alternate gene names: 108758552

Gene position: 2654645-2656858 (Clockwise)

Preceding gene: 108761431

Following gene: 108762096

Centisome position: 29.05

GC content: 68.07

Gene sequence:

>2214_bases
ATGCGTAAGCTCTTCTTCGCTGGCGCGGGCATGGCCGTACTCGTGTCCACCGGCTGTGCGACGACCTCGCAGGAGTCCCA
GAACTTGGCCACCGCGCCCCAGACGACCGCCCCCGCCGCGCCGGCTGCTCCGGAGCAGACCAACCCGCTGATCGCGAAGT
GGACGGGCGCCCATGGCGGCGTTCCGCCGTTCGACCAGGTGAAGGTGGAGCTCTTCAAGCCAGCGCTCGAGGCCGCGATG
GAGCGGACGCGCGGCGAACTGGCGGCCATCGCGAACGACACCTCGGCGCCCACGTTCGAGAACACCATCGTCGCGCTGGA
GTCCGCCGGCAAGACGCAGGGCGAAGTGGAGACGCTCTACGGCATCTGGAGCTCGTCCATGAGCGGGCCGGAGTTCCAGG
CGCTGGAGCGGGAGATGGCGCCGAAGCTGGCCGCCTTCGACGACGAAATCTTCCAGAACGAGGCGCTCTTCCGCCGCATC
GAGGCGGTGTACCAGTCGCCCGACAAGGCGAAGCTGACGCCCGAGCAGCAGCGGCTCACCTGGCTGCACTACACGCGCTT
CGTCCGCTCCGGCGCGAAGCTGGACGCGGCGGCCAAGCAGAAGCTGGCGGCCATCAACCAGCGGCTGGCGTCGCTCTACA
CGTCCTTCAGCCAGAACGTGCTCGCGGACGAAGAGGGCTACACCGTCGTCCTGGAGTCCGAGGCGGACCTGGCGGGCCTG
CCGGACTCCGTGCGCGCGGGCGCCGCCGCCGCGGCCGAGTCGCGCGGTCAGAAGGGCAAGTGGCTCATCACCAACACGCG
CTCCTCCATGGAGCCGTTCCTGACGTACTCGTCGCGGCGCGACCTGCGCGAGAAGGTCTGGCGCAACTACGTCAACCGAG
GTGACAACGGCGACGCGCGCGACAACAACGTCATCATCGCCGAAGTCCTGAAGCTGCGCGCCGAGCGCGCCACGCTGCTG
GGCTACAAGACGCACGCGCACTGGCGGCTGGAGAACGCCATGGCCCGCACGCCCGAGCGCGCCATGGAGCTGATGGAGGC
CGTCTGGAAGCCCGCGGTGGCCCGCGTTCACGAAGAGGTCGCGGACATGCAGCGCGTGGCCAACAAGGAGGGCGCGAAGC
TCAAGATTGAACCCTGGGACTACCGCTACTACGCGGAGAAGGTCCGCAAGGCGAAGTACGACCTGGACCAGAACGAGGTG
AAGCCCTACCTCCAGTTGGAGAAGCTGCGCGAGGGCATGTTCTGGGTGGCCGGCGAGCTGTTCGGCTTCTCCTTCACGCA
GGTGAACGACGTGCCCGTGTTCCACCCCGACGTGCGCGTCTGGGAGGTGAAGGACCAGGCCAGCGGGCGTCACGTGGGCT
TGTGGTACTTCGACCCGTACGCGCGCAAGGGCAAGCGCTCCGGCGCGTGGATGAACGCGTACCGCAGCCAGGAGCGGTTC
CGGGGTGAAGTCACCACCATCGTCTCCAACAACTCCAACTTCGTGAAGGGCCAGCCCGGTGAGCCCGTCCTCATCAGCTG
GGAGGATGCCTCCACGCTGTTCCACGAGTTCGGCCACGCGCTGCACGGCCTCAGCTCCAACGTGACGTACCCGTCGCTGG
CCGGCACCGCGGTGGCGCGCGACTACGTGGAGTTCCCCTCGCAATTGCTGGAGCACTGGCTGTCCACGCCCGAGGTGCTG
AACACCTACGCGCTGCACTACCAGACGGGGAAGCCCATTCCCCAGGCGCTGGTGGACCGCATCGAGAAGGCCGCCACCTT
CAACCAGGGCTTCGGGACGGTGGAGTACCTGTCCAGCGCGCTGGTGGACATGAAGCTGCACCTGGCGGGGGCTACGCCCA
TTGACGCGGACGCCTTCGAGCGCGACACGCTCAACGCGCTGGGCATGCCGAAGGAAATCGTCATGCGGCACCGCACGCCG
CAGTTCGGCCACGTCTTCGCGGGTGACGGATACTCGGCGGGCTACTACAGCTACCTGTGGTCGGACACGCTGACGGCGGA
CGCCTACGAGCGCTTCACCGAAGGCAAGGGCGCCTACGACAAGGACGTGGCCGCGCTCCTGCGCAAGCACGTCTTCTCCG
TGGGCAACACGCTGGACCCGGCCGACGCGTACCGCGCCTTCCGGGGCCGTGAGGCGGGCATCCAGGCCCTGATGCGCAAG
CGCGGCTTCCCCGTGCCTGCCGCGCAGGCCGCGCCGAAGAAGGCCGCGAAGTAG

Upstream 100 bases:

>100_bases
GTTGGTGTGCCCGCGATTCCGTCCCCCGGTTCGCGACGCGATGCCGCTAGGCTGCGTCCCTCTTCAGGTAGCCCCCCTTT
CGTCGGGAGACATCCTCTAC

Downstream 100 bases:

>100_bases
TCGCCCGGTGGCGGGCCCGGGCTACCCCTCCAGCGGGAAGAAGTGGCTGAAGGGGCCCGGGCCCTTGCCCAGGGGCAGGG
GGTGCTCCAGCGCGGCGGTG

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MRKLFFAGAGMAVLVSTGCATTSQESQNLATAPQTTAPAAPAAPEQTNPLIAKWTGAHGGVPPFDQVKVELFKPALEAAM
ERTRGELAAIANDTSAPTFENTIVALESAGKTQGEVETLYGIWSSSMSGPEFQALEREMAPKLAAFDDEIFQNEALFRRI
EAVYQSPDKAKLTPEQQRLTWLHYTRFVRSGAKLDAAAKQKLAAINQRLASLYTSFSQNVLADEEGYTVVLESEADLAGL
PDSVRAGAAAAAESRGQKGKWLITNTRSSMEPFLTYSSRRDLREKVWRNYVNRGDNGDARDNNVIIAEVLKLRAERATLL
GYKTHAHWRLENAMARTPERAMELMEAVWKPAVARVHEEVADMQRVANKEGAKLKIEPWDYRYYAEKVRKAKYDLDQNEV
KPYLQLEKLREGMFWVAGELFGFSFTQVNDVPVFHPDVRVWEVKDQASGRHVGLWYFDPYARKGKRSGAWMNAYRSQERF
RGEVTTIVSNNSNFVKGQPGEPVLISWEDASTLFHEFGHALHGLSSNVTYPSLAGTAVARDYVEFPSQLLEHWLSTPEVL
NTYALHYQTGKPIPQALVDRIEKAATFNQGFGTVEYLSSALVDMKLHLAGATPIDADAFERDTLNALGMPKEIVMRHRTP
QFGHVFAGDGYSAGYYSYLWSDTLTADAYERFTEGKGAYDKDVAALLRKHVFSVGNTLDPADAYRAFRGREAGIQALMRK
RGFPVPAAQAAPKKAAK

Sequences:

>Translated_737_residues
MRKLFFAGAGMAVLVSTGCATTSQESQNLATAPQTTAPAAPAAPEQTNPLIAKWTGAHGGVPPFDQVKVELFKPALEAAM
ERTRGELAAIANDTSAPTFENTIVALESAGKTQGEVETLYGIWSSSMSGPEFQALEREMAPKLAAFDDEIFQNEALFRRI
EAVYQSPDKAKLTPEQQRLTWLHYTRFVRSGAKLDAAAKQKLAAINQRLASLYTSFSQNVLADEEGYTVVLESEADLAGL
PDSVRAGAAAAAESRGQKGKWLITNTRSSMEPFLTYSSRRDLREKVWRNYVNRGDNGDARDNNVIIAEVLKLRAERATLL
GYKTHAHWRLENAMARTPERAMELMEAVWKPAVARVHEEVADMQRVANKEGAKLKIEPWDYRYYAEKVRKAKYDLDQNEV
KPYLQLEKLREGMFWVAGELFGFSFTQVNDVPVFHPDVRVWEVKDQASGRHVGLWYFDPYARKGKRSGAWMNAYRSQERF
RGEVTTIVSNNSNFVKGQPGEPVLISWEDASTLFHEFGHALHGLSSNVTYPSLAGTAVARDYVEFPSQLLEHWLSTPEVL
NTYALHYQTGKPIPQALVDRIEKAATFNQGFGTVEYLSSALVDMKLHLAGATPIDADAFERDTLNALGMPKEIVMRHRTP
QFGHVFAGDGYSAGYYSYLWSDTLTADAYERFTEGKGAYDKDVAALLRKHVFSVGNTLDPADAYRAFRGREAGIQALMRK
RGFPVPAAQAAPKKAAK
>Mature_737_residues
MRKLFFAGAGMAVLVSTGCATTSQESQNLATAPQTTAPAAPAAPEQTNPLIAKWTGAHGGVPPFDQVKVELFKPALEAAM
ERTRGELAAIANDTSAPTFENTIVALESAGKTQGEVETLYGIWSSSMSGPEFQALEREMAPKLAAFDDEIFQNEALFRRI
EAVYQSPDKAKLTPEQQRLTWLHYTRFVRSGAKLDAAAKQKLAAINQRLASLYTSFSQNVLADEEGYTVVLESEADLAGL
PDSVRAGAAAAAESRGQKGKWLITNTRSSMEPFLTYSSRRDLREKVWRNYVNRGDNGDARDNNVIIAEVLKLRAERATLL
GYKTHAHWRLENAMARTPERAMELMEAVWKPAVARVHEEVADMQRVANKEGAKLKIEPWDYRYYAEKVRKAKYDLDQNEV
KPYLQLEKLREGMFWVAGELFGFSFTQVNDVPVFHPDVRVWEVKDQASGRHVGLWYFDPYARKGKRSGAWMNAYRSQERF
RGEVTTIVSNNSNFVKGQPGEPVLISWEDASTLFHEFGHALHGLSSNVTYPSLAGTAVARDYVEFPSQLLEHWLSTPEVL
NTYALHYQTGKPIPQALVDRIEKAATFNQGFGTVEYLSSALVDMKLHLAGATPIDADAFERDTLNALGMPKEIVMRHRTP
QFGHVFAGDGYSAGYYSYLWSDTLTADAYERFTEGKGAYDKDVAALLRKHVFSVGNTLDPADAYRAFRGREAGIQALMRK
RGFPVPAAQAAPKKAAK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=682, Percent_Identity=28.1524926686217, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI14149738, Length=652, Percent_Identity=26.840490797546, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI156105687, Length=624, Percent_Identity=23.2371794871795, Blast_Score=133, Evalue=6e-31,
Organism=Escherichia coli, GI1787819, Length=682, Percent_Identity=38.1231671554252, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789913, Length=691, Percent_Identity=31.6931982633864, Blast_Score=330, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI71999758, Length=591, Percent_Identity=22.165820642978, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32565901, Length=566, Percent_Identity=20.8480565371025, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=610, Percent_Identity=27.0491803278689, Blast_Score=194, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322715, Length=670, Percent_Identity=21.6417910447761, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356111, Length=686, Percent_Identity=23.0320699708455, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI20129717, Length=373, Percent_Identity=26.2734584450402, Blast_Score=117, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 81992; Mature: 81992

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLFFAGAGMAVLVSTGCATTSQESQNLATAPQTTAPAAPAAPEQTNPLIAKWTGAHGG
CCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
VPPFDQVKVELFKPALEAAMERTRGELAAIANDTSAPTFENTIVALESAGKTQGEVETLY
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCCCCCCCEEEEEECCCCCCCHHHHHH
GIWSSSMSGPEFQALEREMAPKLAAFDDEIFQNEALFRRIEAVYQSPDKAKLTPEQQRLT
HHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
WLHYTRFVRSGAKLDAAAKQKLAAINQRLASLYTSFSQNVLADEEGYTVVLESEADLAGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
PDSVRAGAAAAAESRGQKGKWLITNTRSSMEPFLTYSSRRDLREKVWRNYVNRGDNGDAR
CHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNNVIIAEVLKLRAERATLLGYKTHAHWRLENAMARTPERAMELMEAVWKPAVARVHEEV
CCCCHHHHHHHHHHHHHHHEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ADMQRVANKEGAKLKIEPWDYRYYAEKVRKAKYDLDQNEVKPYLQLEKLREGMFWVAGEL
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCHHHHHHHH
FGFSFTQVNDVPVFHPDVRVWEVKDQASGRHVGLWYFDPYARKGKRSGAWMNAYRSQERF
HCCEECEECCCCEECCCCEEEEECCCCCCCEEEEEEECHHHHCCCCCCHHHHHHHHHHHH
RGEVTTIVSNNSNFVKGQPGEPVLISWEDASTLFHEFGHALHGLSSNVTYPSLAGTAVAR
CCCEEEEEECCCCEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
DYVEFPSQLLEHWLSTPEVLNTYALHYQTGKPIPQALVDRIEKAATFNQGFGTVEYLSSA
HHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVDMKLHLAGATPIDADAFERDTLNALGMPKEIVMRHRTPQFGHVFAGDGYSAGYYSYLW
HHHHHEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCEEECCCCCCCCHHHHHH
SDTLTADAYERFTEGKGAYDKDVAALLRKHVFSVGNTLDPADAYRAFRGREAGIQALMRK
HCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
RGFPVPAAQAAPKKAAK
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKLFFAGAGMAVLVSTGCATTSQESQNLATAPQTTAPAAPAAPEQTNPLIAKWTGAHGG
CCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
VPPFDQVKVELFKPALEAAMERTRGELAAIANDTSAPTFENTIVALESAGKTQGEVETLY
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCCCCCCCEEEEEECCCCCCCHHHHHH
GIWSSSMSGPEFQALEREMAPKLAAFDDEIFQNEALFRRIEAVYQSPDKAKLTPEQQRLT
HHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
WLHYTRFVRSGAKLDAAAKQKLAAINQRLASLYTSFSQNVLADEEGYTVVLESEADLAGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
PDSVRAGAAAAAESRGQKGKWLITNTRSSMEPFLTYSSRRDLREKVWRNYVNRGDNGDAR
CHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNNVIIAEVLKLRAERATLLGYKTHAHWRLENAMARTPERAMELMEAVWKPAVARVHEEV
CCCCHHHHHHHHHHHHHHHEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ADMQRVANKEGAKLKIEPWDYRYYAEKVRKAKYDLDQNEVKPYLQLEKLREGMFWVAGEL
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCHHHHHHHH
FGFSFTQVNDVPVFHPDVRVWEVKDQASGRHVGLWYFDPYARKGKRSGAWMNAYRSQERF
HCCEECEECCCCEECCCCEEEEECCCCCCCEEEEEEECHHHHCCCCCCHHHHHHHHHHHH
RGEVTTIVSNNSNFVKGQPGEPVLISWEDASTLFHEFGHALHGLSSNVTYPSLAGTAVAR
CCCEEEEEECCCCEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
DYVEFPSQLLEHWLSTPEVLNTYALHYQTGKPIPQALVDRIEKAATFNQGFGTVEYLSSA
HHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LVDMKLHLAGATPIDADAFERDTLNALGMPKEIVMRHRTPQFGHVFAGDGYSAGYYSYLW
HHHHHEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCEEECCCCCCCCHHHHHH
SDTLTADAYERFTEGKGAYDKDVAALLRKHVFSVGNTLDPADAYRAFRGREAGIQALMRK
HCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
RGFPVPAAQAAPKKAAK
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]