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The map label for this gene is hslV

Identifier: 108762078

GI number: 108762078

Start: 3538498

End: 3539025

Strand: Direct

Name: hslV

Synonym: MXAN_3012

Alternate gene names: 108762078

Gene position: 3538498-3539025 (Clockwise)

Preceding gene: 108759779

Following gene: 108761314

Centisome position: 38.72

GC content: 65.15

Gene sequence:

>528_bases
ATGTTCCACGGCACCACCATCCTCTGCGTGCGGCGTGACGGGAAGGTCGCCATCGCCAGCGACGGCCAGGTCTCCCTCGA
AAAGACCGTGATGAAGAACACGGCGAAGAAGGTCCGCCGGCTGGGCGAAGGCCAGGTGCTCGCCGGCTTCGCTGGCAGCA
CCGCGGACGCTTTCACGCTCTTCGAGCGCTTCGAGGCCAAGCTCAAGGAGCATCAGAAGAACATGGCCCGCGCCTGCGTG
GAGCTGGGCAAGGACTGGCGCACCGACCGCTTCCTCCGCCGGCTGGAAGCGCTCCTCATCGTCGCCGACAAGGAGAAGAC
GTTCATCCTCTCCGGCGCGGGTGACGTGATTGAACCCGACTACGGCATCGCCGCCGTGGGAAGTGGTGGCCCCTACGCGT
TCGCCGCCGCGCGCGCCCTCATGGCGCACACGCAGATGTCTGCTCGCGACGTGGTGCACCAGTCGCTCACCATCGCGGGT
GAAATCGACATCTACACCAACGCCAACATCTCCATCGAAGAGCTCTAG

Upstream 100 bases:

>100_bases
CTGGTGGTGCCGTGGGTGCTTCCTTTTTGAAGTCTGAGAGCAGACAGCCAGTCACTGTTCCTTGGAAACGCCGCGCCCGG
CTTGTTAAACCCCGGGTCCT

Downstream 100 bases:

>100_bases
GAGACACACCCCGTGGCCGAATCGCGCAAGTTGTCCGCCTTCACGCCTCGCGAGGTCGTCAGCGAGCTGGACCGCTACAT
CGTCGGGCAGAACGCCGCCA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTLFERFEAKLKEHQKNMARACV
ELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPDYGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAG
EIDIYTNANISIEEL

Sequences:

>Translated_175_residues
MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTLFERFEAKLKEHQKNMARACV
ELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPDYGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAG
EIDIYTNANISIEEL
>Mature_175_residues
MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTLFERFEAKLKEHQKNMARACV
ELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPDYGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAG
EIDIYTNANISIEEL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=60.233918128655, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_MYXXA (Q84F94)

Other databases:

- EMBL:   AY204472
- ProteinModelPortal:   Q84F94
- SMR:   Q84F94
- MEROPS:   T01.006
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.- [C]

Molecular weight: Translated: 19060; Mature: 19060

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: ACT_SITE 5-5

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTL
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
FERFEAKLKEHQKNMARACVELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCC
YGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAGEIDIYTNANISIEEL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCEEEECC
>Mature Secondary Structure
MFHGTTILCVRRDGKVAIASDGQVSLEKTVMKNTAKKVRRLGEGQVLAGFAGSTADAFTL
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
FERFEAKLKEHQKNMARACVELGKDWRTDRFLRRLEALLIVADKEKTFILSGAGDVIEPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCC
YGIAAVGSGGPYAFAAARALMAHTQMSARDVVHQSLTIAGEIDIYTNANISIEEL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12828649