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The map label for this gene is phoA [H]

Identifier: 108762024

GI number: 108762024

Start: 3001298

End: 3002932

Strand: Reverse

Name: phoA [H]

Synonym: MXAN_2579

Alternate gene names: 108762024

Gene position: 3002932-3001298 (Counterclockwise)

Preceding gene: 108761350

Following gene: 108761514

Centisome position: 32.86

GC content: 69.97

Gene sequence:

>1635_bases
ATGCACCGGAAGACCCCCTTTCACCTTGCCCCCTGGGCGGCCGCACTGATGCTGCTGGCCAGCACCGCGAGTGCGGGGAC
GCTGTATCGAGACCCTTATCTGCAGAAGGTGGGACCGGACACGGCGACGATCGCCTTCCGGCTCGCCGCCAACTGCCAGG
CGGAGGTGCGCTACGGCGAAGGAGCAGCCAACCAGTCGGCTGTCTCCCAGGACGGCGGGAAGTTGCACGCGGTGGTGTTG
ACCGGGCTGAAGCCAGGCACCGAGTACACGTACGAGGTGTCGGCCTGTGGCCTGCGCACGCAGCTCAATCGATTCCGCAC
CGCGCCGGTGCCGGGGACCCGCAGCGTGCACTTCGTGGCGGTGGGCGACTTTGGCACGGGCGGCTCGAACCAGAAGAAGG
TCGCCGCGGCCATGGTCAAGCGGCAGGCGGGGCTGTTCGTCGCGCTGGGGGACAACGCCTACGCCGGTGGCACCGAGGCG
GAAATCCAGAACAACCTCTTCGTGCCCATGGAGGCCCTGCTGGCCCAGGTGCCGTTCTTCGCGGCGCTCGGCAACCATGA
GTACGTGACGAACCAGGGGCAGCCCTACCTGGACAACCTCTACCTGCCCACCAACAACCCCGAGGGCACGGAGCGCTACT
ACTCGTTCGACTGGGGCCACGTGCACTTCGTGGCGCTCGACTCCAACTGCGCCGTGGGACTGGCGTCGGCGGACCGTTGC
ACGCGGGATGCGCAGAAGGCGTGGCTGGAGCGGGACCTCGCGGGGTCGACGCAGCCGTGGAAGATTGTCTTCTTCCACCA
CCCGCCCTGGTCCAGTGGCGAGCACGGCTCGCAGCTCGCCATGCGCCGCCACTTCGGCCCCATCATGGAGAAGTACGGCG
TGGACCTGGTGCTCACCGGGCACGACCACAACTACGAGCGCAGCAAACCCATGAAGGGTGACGCCGTCGCCGGGTCCGGC
GAAAAGGGCATCCCCTACCTCGTGGTGGGCGGCGGCGGCGCGACGCTGAGGAAGCTCCCCGGCAGCAAGCCGGACTGGAG
CGTCATCCGCGACAACCAGGCCTATGGCTTCCTCGACGTGACAGTGGTCGACGGCACGCTCACCGCGCAGTTGCTCGGGG
TGAACGGAGACCCCGTGGACCGCTTCACGCTGCAGAAGGAGCTGCCTCCGCAGGAGCAGCTTCCCGAGGGTGCGATGACG
CTCGTCGTGGAGGGCGAGCGGGGCGTGGCCCCCCACCGCGCCTTCTTCCGGGCCACGCCGTCCCTCGAGGCCGCCACGGT
GACCTGGGATTTCGGCGACGGCGGCACGGCCGAGGGCGAGGCCGCCGAGCACGTCTTCGCCATTCCCGGGCAGTACACGG
TGACGGCCACCGCCACCCAGGGCACGGTGAAGCAGACGGCCACCGCCCTGGTCCAGGTGGCGGAGACTCCCGGTGAGGAG
CCCCAGACGCCGGATGACGGCACGACGGACCCGGGCTCACCGGAGCCCCGCCCTGGGCTTCCGGACTCTCCCGGCCCCCC
GGATGACGGCATGAGCAGCTCGAACGGTGGCTGCACCGCGGGCCCCACCGCCACCCTCCTCCCGGCGGCCCTGGCCCTGC
TGGCCGCGGGTCTGCTCCACCGGCGCCGCAAGTAG

Upstream 100 bases:

>100_bases
GGGCCCTGCCCCACCGTCTCCTACTCCGAGAGGGGGCAGGATGAAGGTCAGCGGTTGAACGGTTGCGCCTCTATCCCGAA
CTTGTTCGGGAGGAGGCCGC

Downstream 100 bases:

>100_bases
GGCCTCCCCGCCCAAGGCCCCCCCGCGCCCTCCTCCTGACGTCACACGGCGGAGGGGCGGGCGTCCGCCAGGGCGGATTT
GCTTTCCGCGCTTGTCAACC

Product: metallophosphoesterase

Products: NA

Alternate protein names: APASE [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MHRKTPFHLAPWAAALMLLASTASAGTLYRDPYLQKVGPDTATIAFRLAANCQAEVRYGEGAANQSAVSQDGGKLHAVVL
TGLKPGTEYTYEVSACGLRTQLNRFRTAPVPGTRSVHFVAVGDFGTGGSNQKKVAAAMVKRQAGLFVALGDNAYAGGTEA
EIQNNLFVPMEALLAQVPFFAALGNHEYVTNQGQPYLDNLYLPTNNPEGTERYYSFDWGHVHFVALDSNCAVGLASADRC
TRDAQKAWLERDLAGSTQPWKIVFFHHPPWSSGEHGSQLAMRRHFGPIMEKYGVDLVLTGHDHNYERSKPMKGDAVAGSG
EKGIPYLVVGGGGATLRKLPGSKPDWSVIRDNQAYGFLDVTVVDGTLTAQLLGVNGDPVDRFTLQKELPPQEQLPEGAMT
LVVEGERGVAPHRAFFRATPSLEAATVTWDFGDGGTAEGEAAEHVFAIPGQYTVTATATQGTVKQTATALVQVAETPGEE
PQTPDDGTTDPGSPEPRPGLPDSPGPPDDGMSSSNGGCTAGPTATLLPAALALLAAGLLHRRRK

Sequences:

>Translated_544_residues
MHRKTPFHLAPWAAALMLLASTASAGTLYRDPYLQKVGPDTATIAFRLAANCQAEVRYGEGAANQSAVSQDGGKLHAVVL
TGLKPGTEYTYEVSACGLRTQLNRFRTAPVPGTRSVHFVAVGDFGTGGSNQKKVAAAMVKRQAGLFVALGDNAYAGGTEA
EIQNNLFVPMEALLAQVPFFAALGNHEYVTNQGQPYLDNLYLPTNNPEGTERYYSFDWGHVHFVALDSNCAVGLASADRC
TRDAQKAWLERDLAGSTQPWKIVFFHHPPWSSGEHGSQLAMRRHFGPIMEKYGVDLVLTGHDHNYERSKPMKGDAVAGSG
EKGIPYLVVGGGGATLRKLPGSKPDWSVIRDNQAYGFLDVTVVDGTLTAQLLGVNGDPVDRFTLQKELPPQEQLPEGAMT
LVVEGERGVAPHRAFFRATPSLEAATVTWDFGDGGTAEGEAAEHVFAIPGQYTVTATATQGTVKQTATALVQVAETPGEE
PQTPDDGTTDPGSPEPRPGLPDSPGPPDDGMSSSNGGCTAGPTATLLPAALALLAAGLLHRRRK
>Mature_544_residues
MHRKTPFHLAPWAAALMLLASTASAGTLYRDPYLQKVGPDTATIAFRLAANCQAEVRYGEGAANQSAVSQDGGKLHAVVL
TGLKPGTEYTYEVSACGLRTQLNRFRTAPVPGTRSVHFVAVGDFGTGGSNQKKVAAAMVKRQAGLFVALGDNAYAGGTEA
EIQNNLFVPMEALLAQVPFFAALGNHEYVTNQGQPYLDNLYLPTNNPEGTERYYSFDWGHVHFVALDSNCAVGLASADRC
TRDAQKAWLERDLAGSTQPWKIVFFHHPPWSSGEHGSQLAMRRHFGPIMEKYGVDLVLTGHDHNYERSKPMKGDAVAGSG
EKGIPYLVVGGGGATLRKLPGSKPDWSVIRDNQAYGFLDVTVVDGTLTAQLLGVNGDPVDRFTLQKELPPQEQLPEGAMT
LVVEGERGVAPHRAFFRATPSLEAATVTWDFGDGGTAEGEAAEHVFAIPGQYTVTATATQGTVKQTATALVQVAETPGEE
PQTPDDGTTDPGSPEPRPGLPDSPGPPDDGMSSSNGGCTAGPTATLLPAALALLAAGLLHRRRK

Specific function: Unknown

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI228008321, Length=324, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI161377455, Length=323, Percent_Identity=24.1486068111455, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI161377453, Length=323, Percent_Identity=24.1486068111455, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI161377451, Length=323, Percent_Identity=24.1486068111455, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4501873, Length=323, Percent_Identity=24.1486068111455, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32566472, Length=370, Percent_Identity=26.2162162162162, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17544356, Length=339, Percent_Identity=27.4336283185841, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559832, Length=341, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71983275, Length=345, Percent_Identity=26.0869565217391, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533158, Length=368, Percent_Identity=26.0869565217391, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115533160, Length=368, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI133931204, Length=326, Percent_Identity=26.6871165644172, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641134, Length=377, Percent_Identity=27.3209549071618, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24641132, Length=350, Percent_Identity=27.1428571428571, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129007, Length=363, Percent_Identity=28.3746556473829, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.1 [H]

Molecular weight: Translated: 57783; Mature: 57783

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50093 PKD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRKTPFHLAPWAAALMLLASTASAGTLYRDPYLQKVGPDTATIAFRLAANCQAEVRYGE
CCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCHHHHCCCCCEEEEEEEECCCEEEEEECC
GAANQSAVSQDGGKLHAVVLTGLKPGTEYTYEVSACGLRTQLNRFRTAPVPGTRSVHFVA
CCCCCCHHHCCCCEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEE
VGDFGTGGSNQKKVAAAMVKRQAGLFVALGDNAYAGGTEAEIQNNLFVPMEALLAQVPFF
EECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCEECCHHHHHHHCCHH
AALGNHEYVTNQGQPYLDNLYLPTNNPEGTERYYSFDWGHVHFVALDSNCAVGLASADRC
EECCCCCEECCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEEECCCCEEEECCHHHH
TRDAQKAWLERDLAGSTQPWKIVFFHHPPWSSGEHGSQLAMRRHFGPIMEKYGVDLVLTG
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEC
HDHNYERSKPMKGDAVAGSGEKGIPYLVVGGGGATLRKLPGSKPDWSVIRDNQAYGFLDV
CCCCCCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEEECCCCEEEEEE
TVVDGTLTAQLLGVNGDPVDRFTLQKELPPQEQLPEGAMTLVVEGERGVAPHRAFFRATP
EEECCEEEEEEEECCCCCCCCEEECCCCCCHHHCCCCEEEEEEECCCCCCCCHHHEECCC
SLEAATVTWDFGDGGTAEGEAAEHVFAIPGQYTVTATATQGTVKQTATALVQVAETPGEE
CCCEEEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
PQTPDDGTTDPGSPEPRPGLPDSPGPPDDGMSSSNGGCTAGPTATLLPAALALLAAGLLH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RRRK
HCCC
>Mature Secondary Structure
MHRKTPFHLAPWAAALMLLASTASAGTLYRDPYLQKVGPDTATIAFRLAANCQAEVRYGE
CCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCHHHHCCCCCEEEEEEEECCCEEEEEECC
GAANQSAVSQDGGKLHAVVLTGLKPGTEYTYEVSACGLRTQLNRFRTAPVPGTRSVHFVA
CCCCCCHHHCCCCEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEE
VGDFGTGGSNQKKVAAAMVKRQAGLFVALGDNAYAGGTEAEIQNNLFVPMEALLAQVPFF
EECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCEECCHHHHHHHCCHH
AALGNHEYVTNQGQPYLDNLYLPTNNPEGTERYYSFDWGHVHFVALDSNCAVGLASADRC
EECCCCCEECCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEEECCCCEEEECCHHHH
TRDAQKAWLERDLAGSTQPWKIVFFHHPPWSSGEHGSQLAMRRHFGPIMEKYGVDLVLTG
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEC
HDHNYERSKPMKGDAVAGSGEKGIPYLVVGGGGATLRKLPGSKPDWSVIRDNQAYGFLDV
CCCCCCCCCCCCCCEECCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEEECCCCEEEEEE
TVVDGTLTAQLLGVNGDPVDRFTLQKELPPQEQLPEGAMTLVVEGERGVAPHRAFFRATP
EEECCEEEEEEEECCCCCCCCEEECCCCCCHHHCCCCEEEEEEECCCCCCCCHHHEECCC
SLEAATVTWDFGDGGTAEGEAAEHVFAIPGQYTVTATATQGTVKQTATALVQVAETPGEE
CCCEEEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
PQTPDDGTTDPGSPEPRPGLPDSPGPPDDGMSSSNGGCTAGPTATLLPAALALLAAGLLH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RRRK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1856159 [H]