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The map label for this gene is rsmB [H]

Identifier: 108761514

GI number: 108761514

Start: 2999748

End: 3001166

Strand: Reverse

Name: rsmB [H]

Synonym: MXAN_2578

Alternate gene names: 108761514

Gene position: 3001166-2999748 (Counterclockwise)

Preceding gene: 108762024

Following gene: 108757442

Centisome position: 32.84

GC content: 72.87

Gene sequence:

>1419_bases
ATGGCCACCCAACGCAAGTCCCGCCCGCACTCGCGGTCGGCCCCGAAGAAGTCCGGCGCTCCGTCCGGGAAGAAGCCCTC
CCCCTCCGAGCGGCCCGAGCGGCCCCTGCGAGAAGACCTGGTCCTTCAGGCCTGCCTGGAGGCGTACGGCTCGGTCCGGC
ACGAGGGCCGCATGGCCGACCGCGCGCTGGACTTCACCCTGCGCCGCAAGGCCAACCTCTACTCCAACGAGCGCCGCGCC
GTGGCCGAGCGCGTCTACGGCCTGCTGCGCCGCCAGCGGACGGTGGACTTCCTGCTGTCCCGCGCCCACCCACGCTTCGA
CAGCCTGGAGACCTCGCGCCAGGACGTGCTCCGCCTGGCCGCCTCACGCGTCCTCTACGGCGAGCCCCACGGCCTGGTGG
CCCGCCAGTCCGCGCTGGCGCCCCCGGATGCGCAAGCCCTGGGTGCCCTTCCCGAAGCCGCCGCCGCCCTGGAGGCCCTG
CCCGCCCGCGAGCGCTTCCCCATCGCCGCGTCGCTGCCGGACTTCCTCGCCGACCGCTTCCTCCAGACGTTCGGCCGGGA
CGCCGCTCGCGCCGCGGAGGCGATGAACGAGCGCGCCCCGCTGGTCGCCCGCGCCAACCTCCTCAAGGGGGACCGCGACG
CGCTGGCGCAGCGGCTGAAAGCGGAGACCGTGGACGTCAAGCCCACGCCGCTGTCGCCCATGGGCCTGGTGCTGGAGACG
CGCATCAACGCCTTCTCCCTGGAGAGCTTCCGCGAAGGCATGCTGGAGCTCCAGGACGAGGGCAGCCAGTTGCTCGGCAT
GCTGGTGGACGCGCCGCCCACGCGCGTGGTGGATGCGTGCGCGGGTGCCGGCGGCAAGACGCTGCAGCTCGCCGCGCAGA
TGAAGAACCGGGGTGACTTGCACGCCCTGGACATCGATGAGCGCCGCATGGAGGACCTGAAGAAGCGCGCGCGCCGCGCG
GGTGTGCACAACGTGCGCGCCCAGCTCATCCCCCACGAGGGCCCGGAGGCCGACGCCGCGCTGACGCCCCTCAAGGGCAA
GGCGGACCGGGTGCTGGTGGACGCGCCGTGCAGCGGCACCGGCACCTTCCGCCGCAAGCCTGACGCGCGCTACCGCCTCA
CGCCGGAGGATTTGGAGATGCACGTGGGCCGGCAGAAGGCCCTGCTGGCGCGCTTCGCCACGCTGGTGAAGCCCGGTGGC
CGGCTCATCTACGGCACGTGCAGCGTGCTGCGGGAGGAGAACGAGAACGTGGTGGAGGACTTCCTCGCGAAGCACCCCGA
GTTCACGGTGAAGCCGGTGGCGGAGCTGCTGGGGGCGGAGCTGGCCGAGAAGGTCGGCCCCGGCCCCTTCCTCCGGCTGG
CGCCTCACACCCACGGGACCGACGGATTCTTCGGCGCCGTCCTCGTCCGCGCGAAGTAA

Upstream 100 bases:

>100_bases
CCTCCTGACGTCACACGGCGGAGGGGCGGGCGTCCGCCAGGGCGGATTTGCTTTCCGCGCTTGTCAACCCGGCCCGAGGA
ATGCAAAGCCGCATTCCGTC

Downstream 100 bases:

>100_bases
CCTGCGGCCGGGGGGAGAGAGACACTGCTCATGCACCGTGCCGTCCGCTACCGCGTCTCCATGCCCCGGCCGCATACGCA
CCTGCTGGAGGTGGAAGCCT

Product: RsmB/NOP family methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MATQRKSRPHSRSAPKKSGAPSGKKPSPSERPERPLREDLVLQACLEAYGSVRHEGRMADRALDFTLRRKANLYSNERRA
VAERVYGLLRRQRTVDFLLSRAHPRFDSLETSRQDVLRLAASRVLYGEPHGLVARQSALAPPDAQALGALPEAAAALEAL
PARERFPIAASLPDFLADRFLQTFGRDAARAAEAMNERAPLVARANLLKGDRDALAQRLKAETVDVKPTPLSPMGLVLET
RINAFSLESFREGMLELQDEGSQLLGMLVDAPPTRVVDACAGAGGKTLQLAAQMKNRGDLHALDIDERRMEDLKKRARRA
GVHNVRAQLIPHEGPEADAALTPLKGKADRVLVDAPCSGTGTFRRKPDARYRLTPEDLEMHVGRQKALLARFATLVKPGG
RLIYGTCSVLREENENVVEDFLAKHPEFTVKPVAELLGAELAEKVGPGPFLRLAPHTHGTDGFFGAVLVRAK

Sequences:

>Translated_472_residues
MATQRKSRPHSRSAPKKSGAPSGKKPSPSERPERPLREDLVLQACLEAYGSVRHEGRMADRALDFTLRRKANLYSNERRA
VAERVYGLLRRQRTVDFLLSRAHPRFDSLETSRQDVLRLAASRVLYGEPHGLVARQSALAPPDAQALGALPEAAAALEAL
PARERFPIAASLPDFLADRFLQTFGRDAARAAEAMNERAPLVARANLLKGDRDALAQRLKAETVDVKPTPLSPMGLVLET
RINAFSLESFREGMLELQDEGSQLLGMLVDAPPTRVVDACAGAGGKTLQLAAQMKNRGDLHALDIDERRMEDLKKRARRA
GVHNVRAQLIPHEGPEADAALTPLKGKADRVLVDAPCSGTGTFRRKPDARYRLTPEDLEMHVGRQKALLARFATLVKPGG
RLIYGTCSVLREENENVVEDFLAKHPEFTVKPVAELLGAELAEKVGPGPFLRLAPHTHGTDGFFGAVLVRAK
>Mature_471_residues
ATQRKSRPHSRSAPKKSGAPSGKKPSPSERPERPLREDLVLQACLEAYGSVRHEGRMADRALDFTLRRKANLYSNERRAV
AERVYGLLRRQRTVDFLLSRAHPRFDSLETSRQDVLRLAASRVLYGEPHGLVARQSALAPPDAQALGALPEAAAALEALP
ARERFPIAASLPDFLADRFLQTFGRDAARAAEAMNERAPLVARANLLKGDRDALAQRLKAETVDVKPTPLSPMGLVLETR
INAFSLESFREGMLELQDEGSQLLGMLVDAPPTRVVDACAGAGGKTLQLAAQMKNRGDLHALDIDERRMEDLKKRARRAG
VHNVRAQLIPHEGPEADAALTPLKGKADRVLVDAPCSGTGTFRRKPDARYRLTPEDLEMHVGRQKALLARFATLVKPGGR
LIYGTCSVLREENENVVEDFLAKHPEFTVKPVAELLGAELAEKVGPGPFLRLAPHTHGTDGFFGAVLVRAK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI23199998, Length=248, Percent_Identity=34.6774193548387, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI8922322, Length=248, Percent_Identity=34.6774193548387, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI270288816, Length=249, Percent_Identity=34.9397590361446, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI270288818, Length=248, Percent_Identity=34.6774193548387, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76150625, Length=314, Percent_Identity=32.8025477707006, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI76150623, Length=314, Percent_Identity=32.8025477707006, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI32698918, Length=205, Percent_Identity=30.7317073170732, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301336155, Length=289, Percent_Identity=26.9896193771626, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI39995082, Length=289, Percent_Identity=26.9896193771626, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI2367212, Length=402, Percent_Identity=27.1144278606965, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87081985, Length=274, Percent_Identity=31.021897810219, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17536757, Length=311, Percent_Identity=31.1897106109325, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71998419, Length=334, Percent_Identity=29.6407185628743, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=247, Percent_Identity=31.1740890688259, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25143471, Length=159, Percent_Identity=36.4779874213836, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=308, Percent_Identity=31.4935064935065, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=184, Percent_Identity=32.6086956521739, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI22024126, Length=290, Percent_Identity=31.3793103448276, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355201, Length=347, Percent_Identity=26.5129682997118, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668781, Length=167, Percent_Identity=31.1377245508982, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356513, Length=166, Percent_Identity=30.7228915662651, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 51742; Mature: 51611

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQRKSRPHSRSAPKKSGAPSGKKPSPSERPERPLREDLVLQACLEAYGSVRHEGRMAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
RALDFTLRRKANLYSNERRAVAERVYGLLRRQRTVDFLLSRAHPRFDSLETSRQDVLRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASRVLYGEPHGLVARQSALAPPDAQALGALPEAAAALEALPARERFPIAASLPDFLADRF
HHHHHCCCCCCCHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LQTFGRDAARAAEAMNERAPLVARANLLKGDRDALAQRLKAETVDVKPTPLSPMGLVLET
HHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RINAFSLESFREGMLELQDEGSQLLGMLVDAPPTRVVDACAGAGGKTLQLAAQMKNRGDL
HCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCE
HALDIDERRMEDLKKRARRAGVHNVRAQLIPHEGPEADAALTPLKGKADRVLVDAPCSGT
EEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
GTFRRKPDARYRLTPEDLEMHVGRQKALLARFATLVKPGGRLIYGTCSVLREENENVVED
CCCCCCCCCCEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHHHHH
FLAKHPEFTVKPVAELLGAELAEKVGPGPFLRLAPHTHGTDGFFGAVLVRAK
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
ATQRKSRPHSRSAPKKSGAPSGKKPSPSERPERPLREDLVLQACLEAYGSVRHEGRMAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
RALDFTLRRKANLYSNERRAVAERVYGLLRRQRTVDFLLSRAHPRFDSLETSRQDVLRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASRVLYGEPHGLVARQSALAPPDAQALGALPEAAAALEALPARERFPIAASLPDFLADRF
HHHHHCCCCCCCHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LQTFGRDAARAAEAMNERAPLVARANLLKGDRDALAQRLKAETVDVKPTPLSPMGLVLET
HHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
RINAFSLESFREGMLELQDEGSQLLGMLVDAPPTRVVDACAGAGGKTLQLAAQMKNRGDL
HCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCE
HALDIDERRMEDLKKRARRAGVHNVRAQLIPHEGPEADAALTPLKGKADRVLVDAPCSGT
EEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
GTFRRKPDARYRLTPEDLEMHVGRQKALLARFATLVKPGGRLIYGTCSVLREENENVVED
CCCCCCCCCCEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHHHHH
FLAKHPEFTVKPVAELLGAELAEKVGPGPFLRLAPHTHGTDGFFGAVLVRAK
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]