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The map label for this gene is clpX

Identifier: 108761752

GI number: 108761752

Start: 2342655

End: 2343938

Strand: Direct

Name: clpX

Synonym: MXAN_2015

Alternate gene names: 108761752

Gene position: 2342655-2343938 (Clockwise)

Preceding gene: 108762291

Following gene: 108760729

Centisome position: 25.63

GC content: 63.63

Gene sequence:

>1284_bases
ATGGCGGGCAAGAACGTGGAGAAGCGAGACAACCAGACCCTCTGCTGCTCCTTCTGTGGAAAGTCACAGAAGGAGGTCAA
GAAGCTCATCGCGGGGCCGACGGTCTACATCTGCGACGAGTGCATCGGGCTGTGCAACGACATCATCGCGGAGGAGATCG
ACCGCGAGGAGACGAAGGACACGAAGCTGCGCATCCCCCGGCCCTCCGAAATCAAGGCGGTCCTGGACGAGTACGTGATT
GGGCAGGAGCGGGCGAAGAAGACGCTCTCCGTCGCCGTGCACAACCACTACAAGCGCATCGAGTCCAAGGTCGCGATGGA
GGACGTGGAGCTCCAGAAGAGCAACATCCTTCTCCTGGGGCCTACCGGTAGCGGCAAGACGTTGCTGGCGCAGACGCTGG
CGCGCATCCTCAACGTGCCCTTCACCATCGCCGACGCGACGTGCCTCACCGAGGCCGGCTACGTGGGCGAGGACGTGGAG
AACATCATCGTCAACCTGCTGCAGGCCGCCGACCACGACATCGAGCGGGCCCAGCGCGGCATCGTCTACATCGACGAAAT
CGACAAGATTGCACGCAAGTCGGAGAACCCCTCCATCACCCGCGACGTCAGCGGCGAGGGCGTTCAGCAGGCGCTGCTCA
AGCTCATCGAAGGCACGGTGGCCAATGTTCCGCCCAAGGGTGGCCGCAAGCACCCGCAGCAGGAGTTCCTGCAGGTGGAC
ACCACCAACATCCTCTTCATCTGCGGCGGCGCCTTCGGCGGGCTGGACCAGGTGATTGAGCGGCGCATGGGCGGTCGCAG
CCTGGGCTTTGGCGCGGACGTGCAGTCCAAGAAGCAACGCAGCCTCACGGAGCTGCTCAAGCACGTGGAGCCGGAGGACC
TGCTGAAGTTCGGCATGATTCCGGAGTTCATCGGCCGCCTGCCCATCATCACCGCGCTGGAGGAACTGGATGAGGCTGCC
CTCATCAACATCCTCAACCAGCCGAAGAACGCGCTCACCAAGCAGTACCGCAAGCTCTTCGAACTGGACGGCGTGACGCT
GAAGTTCACCGACGGCGCCCTCAAGGCCATTGCCAACGAGGCCATCCGCCGCAAGGCGGGCGCCCGTGGCCTGCGCTCCA
TCCTGGAGTCGGCCATGCTGGACGTGATGTACGAAATCCCGTCCCGCAAGACGGCCCGCGAGGTGCTCATCTCCGAGGAA
GTGATTCTCAAGAAGAGCGAGCCGGTGGTGCTGCACGCCCAGCCGGAGAAGGAAGCCGCGGAGCCGAAGAAGGAATCCGC
CTGA

Upstream 100 bases:

>100_bases
GGCGCGTGGACGTTCCGGACGGGGGCTGACTAGATTGGTCCGAGCCAGGAACGGGGTGGAGTTCGGGGGCGGGGGCCTTT
CAGGCGCAGCGAGGGACGAA

Downstream 100 bases:

>100_bases
CGCCAGGGCCCGTAGGGGCCCGGTGTTGTCTGGTTGACGGGGCGCGTCACGGAACCACCCGGTGTGGTCCGGGCGCGCCT
CTTTCGTCAGGGGAGGGGCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MAGKNVEKRDNQTLCCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIDREETKDTKLRIPRPSEIKAVLDEYVI
GQERAKKTLSVAVHNHYKRIESKVAMEDVELQKSNILLLGPTGSGKTLLAQTLARILNVPFTIADATCLTEAGYVGEDVE
NIIVNLLQAADHDIERAQRGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKLIEGTVANVPPKGGRKHPQQEFLQVD
TTNILFICGGAFGGLDQVIERRMGGRSLGFGADVQSKKQRSLTELLKHVEPEDLLKFGMIPEFIGRLPIITALEELDEAA
LINILNQPKNALTKQYRKLFELDGVTLKFTDGALKAIANEAIRRKAGARGLRSILESAMLDVMYEIPSRKTAREVLISEE
VILKKSEPVVLHAQPEKEAAEPKKESA

Sequences:

>Translated_427_residues
MAGKNVEKRDNQTLCCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIDREETKDTKLRIPRPSEIKAVLDEYVI
GQERAKKTLSVAVHNHYKRIESKVAMEDVELQKSNILLLGPTGSGKTLLAQTLARILNVPFTIADATCLTEAGYVGEDVE
NIIVNLLQAADHDIERAQRGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKLIEGTVANVPPKGGRKHPQQEFLQVD
TTNILFICGGAFGGLDQVIERRMGGRSLGFGADVQSKKQRSLTELLKHVEPEDLLKFGMIPEFIGRLPIITALEELDEAA
LINILNQPKNALTKQYRKLFELDGVTLKFTDGALKAIANEAIRRKAGARGLRSILESAMLDVMYEIPSRKTAREVLISEE
VILKKSEPVVLHAQPEKEAAEPKKESA
>Mature_426_residues
AGKNVEKRDNQTLCCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIDREETKDTKLRIPRPSEIKAVLDEYVIG
QERAKKTLSVAVHNHYKRIESKVAMEDVELQKSNILLLGPTGSGKTLLAQTLARILNVPFTIADATCLTEAGYVGEDVEN
IIVNLLQAADHDIERAQRGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKLIEGTVANVPPKGGRKHPQQEFLQVDT
TNILFICGGAFGGLDQVIERRMGGRSLGFGADVQSKKQRSLTELLKHVEPEDLLKFGMIPEFIGRLPIITALEELDEAAL
INILNQPKNALTKQYRKLFELDGVTLKFTDGALKAIANEAIRRKAGARGLRSILESAMLDVMYEIPSRKTAREVLISEEV
ILKKSEPVVLHAQPEKEAAEPKKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=347, Percent_Identity=50.7204610951009, Blast_Score=325, Evalue=4e-89,
Organism=Escherichia coli, GI1786642, Length=409, Percent_Identity=67.2371638141809, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=34.7417840375587, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=342, Percent_Identity=45.6140350877193, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71982908, Length=342, Percent_Identity=45.6140350877193, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=38.5185185185185, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=266, Percent_Identity=39.8496240601504, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=41.7452830188679, Blast_Score=276, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=48.4276729559748, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=48.4276729559748, Blast_Score=296, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_MYXXA (Q9X5N1)

Other databases:

- EMBL:   AF127082
- ProteinModelPortal:   Q9X5N1
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47157; Mature: 47026

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00250 TGF_BETA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKNVEKRDNQTLCCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIDREETKD
CCCCCCCCCCCCEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKLRIPRPSEIKAVLDEYVIGQERAKKTLSVAVHNHYKRIESKVAMEDVELQKSNILLLG
CEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PTGSGKTLLAQTLARILNVPFTIADATCLTEAGYVGEDVENIIVNLLQAADHDIERAQRG
CCCCCHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCC
IVYIDEIDKIARKSENPSITRDVSGEGVQQALLKLIEGTVANVPPKGGRKHPQQEFLQVD
EEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHC
TTNILFICGGAFGGLDQVIERRMGGRSLGFGADVQSKKQRSLTELLKHVEPEDLLKFGMI
CCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFIGRLPIITALEELDEAALINILNQPKNALTKQYRKLFELDGVTLKFTDGALKAIANE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
AIRRKAGARGLRSILESAMLDVMYEIPSRKTAREVLISEEVILKKSEPVVLHAQPEKEAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
EPKKESA
CCCCCCC
>Mature Secondary Structure 
AGKNVEKRDNQTLCCSFCGKSQKEVKKLIAGPTVYICDECIGLCNDIIAEEIDREETKD
CCCCCCCCCCCEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKLRIPRPSEIKAVLDEYVIGQERAKKTLSVAVHNHYKRIESKVAMEDVELQKSNILLLG
CEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PTGSGKTLLAQTLARILNVPFTIADATCLTEAGYVGEDVENIIVNLLQAADHDIERAQRG
CCCCCHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCC
IVYIDEIDKIARKSENPSITRDVSGEGVQQALLKLIEGTVANVPPKGGRKHPQQEFLQVD
EEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHC
TTNILFICGGAFGGLDQVIERRMGGRSLGFGADVQSKKQRSLTELLKHVEPEDLLKFGMI
CCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFIGRLPIITALEELDEAALINILNQPKNALTKQYRKLFELDGVTLKFTDGALKAIANE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
AIRRKAGARGLRSILESAMLDVMYEIPSRKTAREVLISEEVILKKSEPVVLHAQPEKEAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHC
EPKKESA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA