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The map label for this gene is csd [H]

Identifier: 108761569

GI number: 108761569

Start: 1844376

End: 1845512

Strand: Direct

Name: csd [H]

Synonym: MXAN_1570

Alternate gene names: 108761569

Gene position: 1844376-1845512 (Clockwise)

Preceding gene: 108763477

Following gene: 108760532

Centisome position: 20.18

GC content: 71.5

Gene sequence:

>1137_bases
ATGACGCGCTCGCTCGAGTCCTACCGAGACCTCTTCCCCGTGCTGAAGGAGCAGCTCTACCTCAACCACGCCGGTGTGGC
TCCCACCAGCCTGCGCGCCGCCGAGGCCGTGCGCGGGTGGATGGAGGACATCGTCCACCACGGCATCAAGCACGAGCGCG
GCTGGGAGGCCCACTGCGAGCGCGTGCGGGGCCTGGCCGCCCGCCTCATCAACGCCGAGCCCGGCGAGATTGCCTTCGTG
CGCAACACCAGCCACGGCCTGGGCCTGGTGGCCGAGGGGCTGGACTGGACGCCCGGCGACGAGGTCGTCGTCGCATCCTC
GTTGGAGTACCCCTCCAACGTCTATCCCTGGCTGCACCTGAAGGACCGCGGCGTCACCGTGCGCGAAATCCAGACGCCCG
AAGGGGGCGTCACGCCGGAAGCCGTGGCCGCCGCGCTCACCCCGAGCACCCGGCTGGTGGCGGTCTCCTCCGTGCAGTTC
GCCACCGGCTACCGCACGGACCTGGATGCGGTGGGCGCCCTGTGCGAGCGGGCGGGCGTTCTGTTCTGCGTGGACGGCAT
CCAGAGCGTGGGCTGCATCCCCGTGGACGTGAAGAAGAGCCGCATCCACTTCCTCAGCGCGGACAGCCACAAGTGGATGC
TGGGCATCGCCGGCATCGGCTTCCTCTACGTGGCCAAGGACGTCCTGCCCAGGCTGCGGCCCGTGCTGGTGGGCTGGCGC
AGCACCACCGACGCCTGGAACTTCAACCGCAGCCACTTCGAGCTGCGCCCGGACGCGGGCAAGCTGGAGGAGGGCAGCGC
CGCGTACACCGGCATCTACGCCCTGGGCGCCGCGCTGGAGCTGCTGCACGAGGTGGGGGTGGACGCCATCTCCGCGCGCA
TCCGCGAACTGCTGGGCCAACTGGAGACAGGGCTGCGTGGGCTGGGCTGCGACGTGGGGCCCGCGCCGGAGCACCGGGCG
GGCATCCTCACGTTCCTGCCTCCGGAGGGCGAGGCCCGCGCGCTCGGCGCGTGGCTCGCCGGACGAGAGGTGGCCCTCTC
GGTGCGCCGCGGGCGCGTCCGCCTCTCACCCCACTTCTACAACCTGCCCGAGGAGATGGACCGGTTGGTGGAGCTGGTGC
GGACGCACCGCGGCTGA

Upstream 100 bases:

>100_bases
CCCAAGGTGGGACGGAAAAACCACCGCGTCTGTCCACGGCGGACACCCGGCCTTCACGAAGTACGGCGCGGCGCGGCGAC
GTGGCTACACTCCGGGCACC

Downstream 100 bases:

>100_bases
GGGCCCCGGGACTACTGGGCCGGGAAGAGCGGCTCGATGGAGAGGTAGCGCTCGCCCGTGTCGTAGTTGAAGGCGAGCAC
GCGGCTGCCGTCGGTCATCT

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTRSLESYRDLFPVLKEQLYLNHAGVAPTSLRAAEAVRGWMEDIVHHGIKHERGWEAHCERVRGLAARLINAEPGEIAFV
RNTSHGLGLVAEGLDWTPGDEVVVASSLEYPSNVYPWLHLKDRGVTVREIQTPEGGVTPEAVAAALTPSTRLVAVSSVQF
ATGYRTDLDAVGALCERAGVLFCVDGIQSVGCIPVDVKKSRIHFLSADSHKWMLGIAGIGFLYVAKDVLPRLRPVLVGWR
STTDAWNFNRSHFELRPDAGKLEEGSAAYTGIYALGAALELLHEVGVDAISARIRELLGQLETGLRGLGCDVGPAPEHRA
GILTFLPPEGEARALGAWLAGREVALSVRRGRVRLSPHFYNLPEEMDRLVELVRTHRG

Sequences:

>Translated_378_residues
MTRSLESYRDLFPVLKEQLYLNHAGVAPTSLRAAEAVRGWMEDIVHHGIKHERGWEAHCERVRGLAARLINAEPGEIAFV
RNTSHGLGLVAEGLDWTPGDEVVVASSLEYPSNVYPWLHLKDRGVTVREIQTPEGGVTPEAVAAALTPSTRLVAVSSVQF
ATGYRTDLDAVGALCERAGVLFCVDGIQSVGCIPVDVKKSRIHFLSADSHKWMLGIAGIGFLYVAKDVLPRLRPVLVGWR
STTDAWNFNRSHFELRPDAGKLEEGSAAYTGIYALGAALELLHEVGVDAISARIRELLGQLETGLRGLGCDVGPAPEHRA
GILTFLPPEGEARALGAWLAGREVALSVRRGRVRLSPHFYNLPEEMDRLVELVRTHRG
>Mature_377_residues
TRSLESYRDLFPVLKEQLYLNHAGVAPTSLRAAEAVRGWMEDIVHHGIKHERGWEAHCERVRGLAARLINAEPGEIAFVR
NTSHGLGLVAEGLDWTPGDEVVVASSLEYPSNVYPWLHLKDRGVTVREIQTPEGGVTPEAVAAALTPSTRLVAVSSVQFA
TGYRTDLDAVGALCERAGVLFCVDGIQSVGCIPVDVKKSRIHFLSADSHKWMLGIAGIGFLYVAKDVLPRLRPVLVGWRS
TTDAWNFNRSHFELRPDAGKLEEGSAAYTGIYALGAALELLHEVGVDAISARIRELLGQLETGLRGLGCDVGPAPEHRAG
ILTFLPPEGEARALGAWLAGREVALSVRRGRVRLSPHFYNLPEEMDRLVELVRTHRG

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787970, Length=417, Percent_Identity=29.4964028776978, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789175, Length=394, Percent_Identity=26.9035532994924, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994898, Length=228, Percent_Identity=27.1929824561404, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25143064, Length=225, Percent_Identity=28.4444444444444, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=343, Percent_Identity=25.3644314868805, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129463, Length=239, Percent_Identity=27.6150627615063, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41305; Mature: 41174

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSLESYRDLFPVLKEQLYLNHAGVAPTSLRAAEAVRGWMEDIVHHGIKHERGWEAHCE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RVRGLAARLINAEPGEIAFVRNTSHGLGLVAEGLDWTPGDEVVVASSLEYPSNVYPWLHL
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCEEEE
KDRGVTVREIQTPEGGVTPEAVAAALTPSTRLVAVSSVQFATGYRTDLDAVGALCERAGV
ECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCE
LFCVDGIQSVGCIPVDVKKSRIHFLSADSHKWMLGIAGIGFLYVAKDVLPRLRPVLVGWR
EEEECCCCCCCCEEECCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEECC
STTDAWNFNRSHFELRPDAGKLEEGSAAYTGIYALGAALELLHEVGVDAISARIRELLGQ
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LETGLRGLGCDVGPAPEHRAGILTFLPPEGEARALGAWLAGREVALSVRRGRVRLSPHFY
HHHCHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHEEEEECCEEEECCCCC
NLPEEMDRLVELVRTHRG
CCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRSLESYRDLFPVLKEQLYLNHAGVAPTSLRAAEAVRGWMEDIVHHGIKHERGWEAHCE
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RVRGLAARLINAEPGEIAFVRNTSHGLGLVAEGLDWTPGDEVVVASSLEYPSNVYPWLHL
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCEEEE
KDRGVTVREIQTPEGGVTPEAVAAALTPSTRLVAVSSVQFATGYRTDLDAVGALCERAGV
ECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCE
LFCVDGIQSVGCIPVDVKKSRIHFLSADSHKWMLGIAGIGFLYVAKDVLPRLRPVLVGWR
EEEECCCCCCCCEEECCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEECC
STTDAWNFNRSHFELRPDAGKLEEGSAAYTGIYALGAALELLHEVGVDAISARIRELLGQ
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LETGLRGLGCDVGPAPEHRAGILTFLPPEGEARALGAWLAGREVALSVRRGRVRLSPHFY
HHHCHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHEEEEECCEEEECCCCC
NLPEEMDRLVELVRTHRG
CCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]