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The map label for this gene is masK [H]

Identifier: 108761007

GI number: 108761007

Start: 3730998

End: 3732152

Strand: Direct

Name: masK [H]

Synonym: MXAN_3183

Alternate gene names: 108761007

Gene position: 3730998-3732152 (Clockwise)

Preceding gene: 108757646

Following gene: 108758975

Centisome position: 40.82

GC content: 66.84

Gene sequence:

>1155_bases
ATGTCGAAGGCAATCGAGTTCAAGATCCCACGGGGGGCGATCCTCTTTTCGGCGGGCGGAGTCGGCTACGAGTACCGCGA
GGACTTAGGGCCGGCTCACCACGGGATGTCCCTGTTCGTAGCGAGGCTGCGGGCCGCGTCCGGCGCGCCGCGTGGGAAGG
TGCTGCTCAAGGCGGTTCCGGCTCCATCGGAAACGGACGGCGCCCGGGTCATGCGTGCGCGCGCGAAGCTCGACGAGCAG
GTTCGCCTTGCGGCCTTCCTCAAGCACCCGGCCATCCTCAAGGTTCATGGGCTGCACAAGGTCGAGGGCTATTGGTACGT
CAGCACGGAGCACCCGGACGGCCACTCCCTGAATGAGTTGCTGACGCTCGTTGGTGAGAGTCAGCGATGGTTCTCGCCGC
TCTTCGTGCTCTATGTCGGGGCGCAGGTCGCAGCGGCTCTTGAGCACGCGCACGCCGCGAAGGACGAGCAGGGACGGCCG
CTAAACATCGTTCATCGAGCCGTTGACGTTGAGCACATCTTCGTCAACTGGGACGGGACGGTTCAGCTCGCCGACTTCGG
CCTCGCGCTGTCCGACTTGCCGGGGCGCGTAGCTTCATCCGCGCGCGGCCCTTTGGGGGACCACTTCTACTCATCACCGG
AGATGCTGCTCGGAGGGAGCGTCGACGCCCGCGCCGACCTCTTCACGCTGGGCGTCGTGCTGCTCGAACTGGCAACGGGG
AAGAACCTGCTTTTCTGCCCGGACGACATCACGCCCGACGTCATGGCCTCGTTGCCCACGAAGAAGCGTCGGCGGGTTGC
TCGGGCGGTCAAGCGGGCTACGCTCGCAGGGGCGCCGCCGTTGGTGGCCGACGCAATTTGGCGCGCGGCGACACTGACGG
TTGCGGACGTAGACGCAATGACCGAAGGGCTCCCCCAGGGCCTGCGAGTGACGCTGAACCGGCTACTTCGGGTTGCCCCT
CGGGAGCGTTACCAGTCGGCGGGGGAGTTGGCGGCCGACCTGACGGCCTGGCTTGGCGGCACTTTCGCGAAGGCCGACGC
CGCAGCCGAGCTGAAGTCTCGGCCTGCTCAGGCAGAAGCGGCGCTGGATTCGATGGCGACCCTGCCGCCTCGCGGTCGCG
GCAAGCGCAAGCCGGATAATGTGACGACGGCGTGA

Upstream 100 bases:

>100_bases
TTTGACCCCATGACCTGTGAGGGCGTTCCCTCAACCGGATGCCGCAGGTAGCGTTTTCCTCGTCGCGTTGGTTGCGAGTT
CGCACACGAGGGGCAACGGC

Downstream 100 bases:

>100_bases
TTGATGTGCTTCTGAGCCAGTCGACGCAGTCGGGAAACAGGCTGCGTTGGCCCGCGAAGGAACAACACGGAGCGGCCAAA
AACAAACGGGGTTGGACGGT

Product: putative serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSKAIEFKIPRGAILFSAGGVGYEYREDLGPAHHGMSLFVARLRAASGAPRGKVLLKAVPAPSETDGARVMRARAKLDEQ
VRLAAFLKHPAILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFSPLFVLYVGAQVAAALEHAHAAKDEQGRP
LNIVHRAVDVEHIFVNWDGTVQLADFGLALSDLPGRVASSARGPLGDHFYSSPEMLLGGSVDARADLFTLGVVLLELATG
KNLLFCPDDITPDVMASLPTKKRRRVARAVKRATLAGAPPLVADAIWRAATLTVADVDAMTEGLPQGLRVTLNRLLRVAP
RERYQSAGELAADLTAWLGGTFAKADAAAELKSRPAQAEAALDSMATLPPRGRGKRKPDNVTTA

Sequences:

>Translated_384_residues
MSKAIEFKIPRGAILFSAGGVGYEYREDLGPAHHGMSLFVARLRAASGAPRGKVLLKAVPAPSETDGARVMRARAKLDEQ
VRLAAFLKHPAILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFSPLFVLYVGAQVAAALEHAHAAKDEQGRP
LNIVHRAVDVEHIFVNWDGTVQLADFGLALSDLPGRVASSARGPLGDHFYSSPEMLLGGSVDARADLFTLGVVLLELATG
KNLLFCPDDITPDVMASLPTKKRRRVARAVKRATLAGAPPLVADAIWRAATLTVADVDAMTEGLPQGLRVTLNRLLRVAP
RERYQSAGELAADLTAWLGGTFAKADAAAELKSRPAQAEAALDSMATLPPRGRGKRKPDNVTTA
>Mature_383_residues
SKAIEFKIPRGAILFSAGGVGYEYREDLGPAHHGMSLFVARLRAASGAPRGKVLLKAVPAPSETDGARVMRARAKLDEQV
RLAAFLKHPAILKVHGLHKVEGYWYVSTEHPDGHSLNELLTLVGESQRWFSPLFVLYVGAQVAAALEHAHAAKDEQGRPL
NIVHRAVDVEHIFVNWDGTVQLADFGLALSDLPGRVASSARGPLGDHFYSSPEMLLGGSVDARADLFTLGVVLLELATGK
NLLFCPDDITPDVMASLPTKKRRRVARAVKRATLAGAPPLVADAIWRAATLTVADVDAMTEGLPQGLRVTLNRLLRVAPR
ERYQSAGELAADLTAWLGGTFAKADAAAELKSRPAQAEAALDSMATLPPRGRGKRKPDNVTTA

Specific function: Essential for growth. Interacts with mglA to control social gliding motility [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4505373, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI24308326, Length=171, Percent_Identity=25.1461988304094, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI41872673, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116089335, Length=171, Percent_Identity=25.1461988304094, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI133951926, Length=180, Percent_Identity=27.2222222222222, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI133951912, Length=180, Percent_Identity=27.2222222222222, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI133901968, Length=282, Percent_Identity=24.113475177305, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133901970, Length=282, Percent_Identity=24.113475177305, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568289, Length=248, Percent_Identity=25.4032258064516, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653590, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653588, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653592, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653586, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 41222; Mature: 41091

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAIEFKIPRGAILFSAGGVGYEYREDLGPAHHGMSLFVARLRAASGAPRGKVLLKAVP
CCCCEEEECCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECC
APSETDGARVMRARAKLDEQVRLAAFLKHPAILKVHGLHKVEGYWYVSTEHPDGHSLNEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECEEEEEEECCCCCCCHHHH
LTLVGESQRWFSPLFVLYVGAQVAAALEHAHAAKDEQGRPLNIVHRAVDVEHIFVNWDGT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEECCCE
VQLADFGLALSDLPGRVASSARGPLGDHFYSSPEMLLGGSVDARADLFTLGVVLLELATG
EEEEECCCHHHCCCCHHHHCCCCCCCCHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
KNLLFCPDDITPDVMASLPTKKRRRVARAVKRATLAGAPPLVADAIWRAATLTVADVDAM
CEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEHHHHHH
TEGLPQGLRVTLNRLLRVAPRERYQSAGELAADLTAWLGGTFAKADAAAELKSRPAQAEA
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHH
ALDSMATLPPRGRGKRKPDNVTTA
HHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKAIEFKIPRGAILFSAGGVGYEYREDLGPAHHGMSLFVARLRAASGAPRGKVLLKAVP
CCCEEEECCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECC
APSETDGARVMRARAKLDEQVRLAAFLKHPAILKVHGLHKVEGYWYVSTEHPDGHSLNEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECEEEEEEECCCCCCCHHHH
LTLVGESQRWFSPLFVLYVGAQVAAALEHAHAAKDEQGRPLNIVHRAVDVEHIFVNWDGT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEECCCE
VQLADFGLALSDLPGRVASSARGPLGDHFYSSPEMLLGGSVDARADLFTLGVVLLELATG
EEEEECCCHHHCCCCHHHHCCCCCCCCHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
KNLLFCPDDITPDVMASLPTKKRRRVARAVKRATLAGAPPLVADAIWRAATLTVADVDAM
CEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEHHHHHH
TEGLPQGLRVTLNRLLRVAPRERYQSAGELAADLTAWLGGTFAKADAAAELKSRPAQAEA
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHH
ALDSMATLPPRGRGKRKPDNVTTA
HHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2464581 [H]