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The map label for this gene is truA1 [H]

Identifier: 108760886

GI number: 108760886

Start: 4976766

End: 4977611

Strand: Direct

Name: truA1 [H]

Synonym: MXAN_4057

Alternate gene names: 108760886

Gene position: 4976766-4977611 (Clockwise)

Preceding gene: 108761867

Following gene: 108757028

Centisome position: 54.45

GC content: 70.69

Gene sequence:

>846_bases
GTGCTCCCCTCCAACTCCAAGCGGATTCCCGTCGCACTGTGGATCTGGTACCGCGGCGGAATCTTCCGCGGCTTCCAGCG
CCAACCCGAGGGCCCCACCGTCCAGTCAGCCCTGGAAGAAGCGCTGCGGTCCGTGGGGGTGCCGGCGACCTTGATGCCTT
CGGGGCGCACGGACCGGGGCGTCCACGCCCGGATGCAGGTGGTGAGCGTCCGGCTGGAAGCGGGCGACTCGGCGGAGTCC
CTGGAGAAGCGGCTCCCGCCCCGGTTGCCACCGGGCCTGGGCCTGTGCGGGGTGCGCCGGCCCACGTCCTTTCATGCGCA
GTGGAGCGCATGCGGCAAGGAGTACCGCTACCGGTTCCAGTTGGGCGGGGCCGTGATGCCCGAATGGGCGCCCTATGCGC
TGGACGTGTCCGCGGAGCCGCTGCTCCAGGCCACGGCGGTGACGCCGGAGCGGTTGGCGGCGCTGCTGCGTTCAGCGGAA
GGGACGCGGGACTTCATCGCGTTCCATGAGAAGTCCAGTCCACGCAAGCCGCGCACGCTGGAGTCCGCCACCCTGCACGC
GCTGGGCGGTGGGCTCTACGAGGCTCGGCTGCGCGGGGACGGCTTCGCGCGCTACCAGATCCGCTATTTGGTGGGGAGCG
CGTTGAAGGTGGCCGCGGGGCTGCTGCCGGAAGAGGCGTGGCTCGCGGCACTCGAGACGGGTCAGGCCATGGAAGGCTTC
AAGGCGCCCGCTCACGGCCTCGTGCTCTGGGAGGTTCGCTACCCTCCCCAAGTGGACCCCTTCACCGCCGGGGAGCGTCT
CCATCCCCCGGGGCTTCCGCTGGAGCCACCCTTCCACATCGGGTAA

Upstream 100 bases:

>100_bases
TGCTTGAAGAGCCAGAGTCCGTCCACGTCCGCCGCAAGGTCTTGTCCAGCCGCCATTTTGCGCGCGAGTATCCCGTGGTT
CCCCACACCCAATCAACGGC

Downstream 100 bases:

>100_bases
CGCGCGGTGGGGCCCGGACGGCCGTCTTCAGTCGACGAGCCGCTCTTCGTACTTCGCGAGCAGATCGGAGATGGCCTCGC
GGAGGTACTCGCTCTGACGG

Product: putative tRNA pseudouridine synthase A

Products: NA

Alternate protein names: tRNA pseudouridylate synthase I 1; tRNA-uridine isomerase I 1 [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MLPSNSKRIPVALWIWYRGGIFRGFQRQPEGPTVQSALEEALRSVGVPATLMPSGRTDRGVHARMQVVSVRLEAGDSAES
LEKRLPPRLPPGLGLCGVRRPTSFHAQWSACGKEYRYRFQLGGAVMPEWAPYALDVSAEPLLQATAVTPERLAALLRSAE
GTRDFIAFHEKSSPRKPRTLESATLHALGGGLYEARLRGDGFARYQIRYLVGSALKVAAGLLPEEAWLAALETGQAMEGF
KAPAHGLVLWEVRYPPQVDPFTAGERLHPPGLPLEPPFHIG

Sequences:

>Translated_281_residues
MLPSNSKRIPVALWIWYRGGIFRGFQRQPEGPTVQSALEEALRSVGVPATLMPSGRTDRGVHARMQVVSVRLEAGDSAES
LEKRLPPRLPPGLGLCGVRRPTSFHAQWSACGKEYRYRFQLGGAVMPEWAPYALDVSAEPLLQATAVTPERLAALLRSAE
GTRDFIAFHEKSSPRKPRTLESATLHALGGGLYEARLRGDGFARYQIRYLVGSALKVAAGLLPEEAWLAALETGQAMEGF
KAPAHGLVLWEVRYPPQVDPFTAGERLHPPGLPLEPPFHIG
>Mature_281_residues
MLPSNSKRIPVALWIWYRGGIFRGFQRQPEGPTVQSALEEALRSVGVPATLMPSGRTDRGVHARMQVVSVRLEAGDSAES
LEKRLPPRLPPGLGLCGVRRPTSFHAQWSACGKEYRYRFQLGGAVMPEWAPYALDVSAEPLLQATAVTPERLAALLRSAE
GTRDFIAFHEKSSPRKPRTLESATLHALGGGLYEARLRGDGFARYQIRYLVGSALKVAAGLLPEEAWLAALETGQAMEGF
KAPAHGLVLWEVRYPPQVDPFTAGERLHPPGLPLEPPFHIG

Specific function: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs [H]

COG id: COG0101

COG function: function code J; Pseudouridylate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA pseudouridine synthase truA family [H]

Homologues:

Organism=Escherichia coli, GI1788657, Length=260, Percent_Identity=30.3846153846154, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001406
- InterPro:   IPR020097
- InterPro:   IPR020095
- InterPro:   IPR020094 [H]

Pfam domain/function: PF01416 PseudoU_synth_1 [H]

EC number: =5.4.99.12 [H]

Molecular weight: Translated: 30773; Mature: 30773

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSNSKRIPVALWIWYRGGIFRGFQRQPEGPTVQSALEEALRSVGVPATLMPSGRTDRG
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCC
VHARMQVVSVRLEAGDSAESLEKRLPPRLPPGLGLCGVRRPTSFHAQWSACGKEYRYRFQ
HHHEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHEEEEE
LGGAVMPEWAPYALDVSAEPLLQATAVTPERLAALLRSAEGTRDFIAFHEKSSPRKPRTL
ECCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCH
ESATLHALGGGLYEARLRGDGFARYQIRYLVGSALKVAAGLLPEEAWLAALETGQAMEGF
HHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCC
KAPAHGLVLWEVRYPPQVDPFTAGERLHPPGLPLEPPFHIG
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPSNSKRIPVALWIWYRGGIFRGFQRQPEGPTVQSALEEALRSVGVPATLMPSGRTDRG
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCC
VHARMQVVSVRLEAGDSAESLEKRLPPRLPPGLGLCGVRRPTSFHAQWSACGKEYRYRFQ
HHHEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCHHHEEEEE
LGGAVMPEWAPYALDVSAEPLLQATAVTPERLAALLRSAEGTRDFIAFHEKSSPRKPRTL
ECCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCH
ESATLHALGGGLYEARLRGDGFARYQIRYLVGSALKVAAGLLPEEAWLAALETGQAMEGF
HHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCC
KAPAHGLVLWEVRYPPQVDPFTAGERLHPPGLPLEPPFHIG
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA