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The map label for this gene is pgsA [H]

Identifier: 108760805

GI number: 108760805

Start: 5807724

End: 5808329

Strand: Reverse

Name: pgsA [H]

Synonym: MXAN_4626

Alternate gene names: 108760805

Gene position: 5808329-5807724 (Counterclockwise)

Preceding gene: 108760794

Following gene: 108758320

Centisome position: 63.55

GC content: 65.18

Gene sequence:

>606_bases
GTGCAGGAGTTCTGGAACCTGCCCAACATGCTCACGTTGGGGCGCATCCTCATCATTCCGCTCTTCGTGTGGCTGACCTA
CGACGCGGACCCCCTCAACTCGCTGCTGGCGGGGCTCGTCTTCGCGGTGGCCGCCATCACTGACGTGGTTGATGGCTACC
TCGCGCGGAAGTGGAACCTCATCACCGTGGTCGGCAAGTTCATGGACCCGCTGGCCGACAAGCTCATCGCCATGGCGGCC
CTGGTGATGATGGTGCGGCTGGGGCGCATCGCCGCGTGGGTCGTCATCGTCCTGCTGGCGCGGGAGCTCATCGTCAGCGG
GCTGCGCACCATCGCCGCCAGCGAGGGCATGGTCATCGCCGCGGGCCAGGAGGGGAAGTGGAAGACGTCCCTCCAACTGG
TGGGCATCATCTCGCTCTGCGTCCACTACGTGCATCCACTGGAGTTCGGCACCTTCTCCGTGCCGGTGGACTACAACCTG
GTGGGCCAGGTGCTCGTCTACCTGTCTGGTGCCTTCTCGGTGTGGAGCGCGGTGGTCTACTTCCGGGCGTTCCTGGCCAT
GTTGGCGAAGCGTGGGGGGGAGCCCGACCCCGCGAAAAGTGTTTGA

Upstream 100 bases:

>100_bases
TAGAAGGGCCCCTGCCATGGCCACGGACCGAGCGGCGCGGAAACAGCGGAAGCGAGAGGAGCGCGCCCGGAAGCGCGCGG
CGCGCAAGCCCAGCGTGTTG

Downstream 100 bases:

>100_bases
CGGGTCCGGAAGGGCTCTGTATACCCCACCTCACTTCCGGCCCGGCGGTCACACGACGGTGACGGAAGCGTAGCACCTGA
TGCGGGAATAGCTCAGCGGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MQEFWNLPNMLTLGRILIIPLFVWLTYDADPLNSLLAGLVFAVAAITDVVDGYLARKWNLITVVGKFMDPLADKLIAMAA
LVMMVRLGRIAAWVVIVLLARELIVSGLRTIAASEGMVIAAGQEGKWKTSLQLVGIISLCVHYVHPLEFGTFSVPVDYNL
VGQVLVYLSGAFSVWSAVVYFRAFLAMLAKRGGEPDPAKSV

Sequences:

>Translated_201_residues
MQEFWNLPNMLTLGRILIIPLFVWLTYDADPLNSLLAGLVFAVAAITDVVDGYLARKWNLITVVGKFMDPLADKLIAMAA
LVMMVRLGRIAAWVVIVLLARELIVSGLRTIAASEGMVIAAGQEGKWKTSLQLVGIISLCVHYVHPLEFGTFSVPVDYNL
VGQVLVYLSGAFSVWSAVVYFRAFLAMLAKRGGEPDPAKSV
>Mature_201_residues
MQEFWNLPNMLTLGRILIIPLFVWLTYDADPLNSLLAGLVFAVAAITDVVDGYLARKWNLITVVGKFMDPLADKLIAMAA
LVMMVRLGRIAAWVVIVLLARELIVSGLRTIAASEGMVIAAGQEGKWKTSLQLVGIISLCVHYVHPLEFGTFSVPVDYNL
VGQVLVYLSGAFSVWSAVVYFRAFLAMLAKRGGEPDPAKSV

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=183, Percent_Identity=34.9726775956284, Blast_Score=92, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320059, Length=104, Percent_Identity=38.4615384615385, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21968; Mature: 21968

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFWNLPNMLTLGRILIIPLFVWLTYDADPLNSLLAGLVFAVAAITDVVDGYLARKWNL
CCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVVGKFMDPLADKLIAMAALVMMVRLGRIAAWVVIVLLARELIVSGLRTIAASEGMVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AGQEGKWKTSLQLVGIISLCVHYVHPLEFGTFSVPVDYNLVGQVLVYLSGAFSVWSAVVY
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
FRAFLAMLAKRGGEPDPAKSV
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQEFWNLPNMLTLGRILIIPLFVWLTYDADPLNSLLAGLVFAVAAITDVVDGYLARKWNL
CCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVVGKFMDPLADKLIAMAALVMMVRLGRIAAWVVIVLLARELIVSGLRTIAASEGMVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AGQEGKWKTSLQLVGIISLCVHYVHPLEFGTFSVPVDYNLVGQVLVYLSGAFSVWSAVVY
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
FRAFLAMLAKRGGEPDPAKSV
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA