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The map label for this gene is torS [H]

Identifier: 108760711

GI number: 108760711

Start: 369075

End: 371150

Strand: Direct

Name: torS [H]

Synonym: MXAN_0314

Alternate gene names: 108760711

Gene position: 369075-371150 (Clockwise)

Preceding gene: 108760606

Following gene: 108757979

Centisome position: 4.04

GC content: 70.33

Gene sequence:

>2076_bases
ATGGGAACTGATACTGATACATGTTTGCCGCGTGTACTTGTGACGGCCACGTATTCGTGTCGACATGGAGCCATTCTGAA
CGACCGATTCCAGGCGGCTCCGGCGCCCGACATGGATGTGCTGCTGGTGGCGCTCGAGGAAGCGGAGCGGCACCAGCCTG
AGGGCTGCATGGTGTTGCACGCCGTGCGGGACGCGGCGGGAGCGCTCGTCGACTTCCAGTGGGCCTGGGCGAATCCCGCG
GGTGCGCGCGCACTGGGGCACGCCGCTCCGGAGTTGCTGAGAGGCCGGCGGCTGCGCGAGCTGATGCCGGGCTCGGGTCT
GGCCTCCCGGGTGGACCTGCTCCGGAACGTGGTGGAGGCGGGCCGGCCGGCTGCGGACAGCTTCCAGGAAGGGGACGTGT
GGCTTCAGGGAACGGCGGTGCCGCTCCGGGACGGTGTCCTGCTGCGCCTGCGTGACATCACCAGCGCCCTGCGGTTGGAG
GAGAGCGTCCGCGAAACCCTGGACTGGGTGCGGAGCATGCTGGAGGCCACACCCGACGCGTTCTTCACGTTGGATGCGGA
CTGGCGAATCACCTTCGTGAACCACGAGGCCGCGGCCCTCAGCGGGCGTTCGCAGGAGCAGCTCTTCCGGCAGATTCTGT
GGCAGGCGTGCCCGGAGTTGCTGGGCACGCGGATGGAGCGGGAGCTGCGCCGGGTCGCGAGCGGCGCGGGCCACACCATC
TTCGAATGGCGCGCCACGCCTGGACGCTGGCATGAGGTGCACGCCTGGGGCGCCAACGGCAACGTGTCCATTTTCGGGCG
GGACGTCACCGCCAGGAAGCAGGCGGAGGCGGAGCGGGACGTGCTTCTGTCGCGCGAGCACTCGGGCCGCCTGGAAGCCG
AGGCCCTGGTCCACGAGCGCACCCGCGAACTCATGGCCGCGCGTGAGCGACTGGTGCAGTCGGAGAAGCTGGCCATGGCG
GGACAGCTCGCGGCGGGCGTGGGGCACGAAATCAACAACCCGCTCTCCTACGTCGTGGGGAACCTGCAGTTCGCGCTGGA
GCAGCTCGAGCCCCTCGCAACGCAGGGCGCGGTGCGTGAATCATTGGCCCGCGCGCTGGGCGAGGCGATGGAGGCCCTGC
GCGAGGCGAAGGAAGGCGCCGAGCGCATCCGCACCACCGTCCGTGATTTGCAGATCTTCGCTCGAGCGGAGGAGCCGCAA
CTGTCGCCCGTGGACGTGCACGCGGCGCTGGAGTTCGGCCTCTCCATGGCGATGCCGCACCTGCGCCACCGGGCCCGCGT
CGAGAAGCGCCTGGGCCCGGTGCCCACGGTGATGGCGCACGAGACGCGGCTGGGGCAGGTGTTCCTCCAACTGCTCGTCA
ACGCCGCGCAGGCCATCCCGGAAGGGGACGTGGCGCGCTACCAGGTGACGCTCTCCACCTGGAGGGACGGCGCGACGGTG
GTGGTGGAGGTGGCGGACAACGGCCACGGCATGGCGCCCGAGGTCCTGGAGCGCGCCTTCGAGCCCTTCTTCACCACCCG
TCCCCTGGGGGAGGGCGCTGGACTCGGCCTGTCCACCAGCCTGGGCCTGGTGCGAGGCATGGGAGGCGAGCTGTCGGCAT
CGAGCGCGCCGGGCCTGGGCAGTGTCTTCCAGGTGCGGCTGCCCACCACCGACGCGGACGCGCCAGCCGTGCGGGTGGCG
GAGGACACGGACCTTCCCGGACGGAAGCGGGTGCTGGTGGTGGATGACGAGCCGCTGCTCGCCTCGGTGCTGGGCCGCAT
CCTCGGCGTGCGTCACGAGGTGGTGGTGGTCCACAGCGGGCGCGAGGCGTTGGACACGCTGGCGCGCGACGCGGACTTCG
ACCGCATCTTCTGTGACTTGATGATGGGGGACCTGACGGGGATGGACGTGTACGACGCGCTGTCCTCGCGTCAGCCGGAG
CTGCTCGCGCGCTTCGTCTTCATGACGGGCGGAGGCTTCTCCGAGCGAGCACGGACCTTCCTCCAGTCGGTGCCGGTGCC
GCGCATCGAAAAGCCGTTCGAGCTGGGCGTCCTGCACGCGCTGGTGGAGGACGCCCCGCCGCGCGCCGGTCCCTGA

Upstream 100 bases:

>100_bases
CGGTGATGAGGGTGGGCGTCATGGGCGGCCGAGGAGCCTAGCCGCCCGGGCGTCCCCTGCGCGCGCGAGCCAGGTCAAGC
GGCGGTTGGCCGACAGACAC

Downstream 100 bases:

>100_bases
GAAGGGCGGCCGGCGCGCGACTCGGAAGCGGTGTGACTACAACTTCACTTCTTCCCGGTCGGGCTGGGTGATGTAGCCGG
AGCCTGCTGCCACCAGCTTG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MGTDTDTCLPRVLVTATYSCRHGAILNDRFQAAPAPDMDVLLVALEEAERHQPEGCMVLHAVRDAAGALVDFQWAWANPA
GARALGHAAPELLRGRRLRELMPGSGLASRVDLLRNVVEAGRPAADSFQEGDVWLQGTAVPLRDGVLLRLRDITSALRLE
ESVRETLDWVRSMLEATPDAFFTLDADWRITFVNHEAAALSGRSQEQLFRQILWQACPELLGTRMERELRRVASGAGHTI
FEWRATPGRWHEVHAWGANGNVSIFGRDVTARKQAEAERDVLLSREHSGRLEAEALVHERTRELMAARERLVQSEKLAMA
GQLAAGVGHEINNPLSYVVGNLQFALEQLEPLATQGAVRESLARALGEAMEALREAKEGAERIRTTVRDLQIFARAEEPQ
LSPVDVHAALEFGLSMAMPHLRHRARVEKRLGPVPTVMAHETRLGQVFLQLLVNAAQAIPEGDVARYQVTLSTWRDGATV
VVEVADNGHGMAPEVLERAFEPFFTTRPLGEGAGLGLSTSLGLVRGMGGELSASSAPGLGSVFQVRLPTTDADAPAVRVA
EDTDLPGRKRVLVVDDEPLLASVLGRILGVRHEVVVVHSGREALDTLARDADFDRIFCDLMMGDLTGMDVYDALSSRQPE
LLARFVFMTGGGFSERARTFLQSVPVPRIEKPFELGVLHALVEDAPPRAGP

Sequences:

>Translated_691_residues
MGTDTDTCLPRVLVTATYSCRHGAILNDRFQAAPAPDMDVLLVALEEAERHQPEGCMVLHAVRDAAGALVDFQWAWANPA
GARALGHAAPELLRGRRLRELMPGSGLASRVDLLRNVVEAGRPAADSFQEGDVWLQGTAVPLRDGVLLRLRDITSALRLE
ESVRETLDWVRSMLEATPDAFFTLDADWRITFVNHEAAALSGRSQEQLFRQILWQACPELLGTRMERELRRVASGAGHTI
FEWRATPGRWHEVHAWGANGNVSIFGRDVTARKQAEAERDVLLSREHSGRLEAEALVHERTRELMAARERLVQSEKLAMA
GQLAAGVGHEINNPLSYVVGNLQFALEQLEPLATQGAVRESLARALGEAMEALREAKEGAERIRTTVRDLQIFARAEEPQ
LSPVDVHAALEFGLSMAMPHLRHRARVEKRLGPVPTVMAHETRLGQVFLQLLVNAAQAIPEGDVARYQVTLSTWRDGATV
VVEVADNGHGMAPEVLERAFEPFFTTRPLGEGAGLGLSTSLGLVRGMGGELSASSAPGLGSVFQVRLPTTDADAPAVRVA
EDTDLPGRKRVLVVDDEPLLASVLGRILGVRHEVVVVHSGREALDTLARDADFDRIFCDLMMGDLTGMDVYDALSSRQPE
LLARFVFMTGGGFSERARTFLQSVPVPRIEKPFELGVLHALVEDAPPRAGP
>Mature_690_residues
GTDTDTCLPRVLVTATYSCRHGAILNDRFQAAPAPDMDVLLVALEEAERHQPEGCMVLHAVRDAAGALVDFQWAWANPAG
ARALGHAAPELLRGRRLRELMPGSGLASRVDLLRNVVEAGRPAADSFQEGDVWLQGTAVPLRDGVLLRLRDITSALRLEE
SVRETLDWVRSMLEATPDAFFTLDADWRITFVNHEAAALSGRSQEQLFRQILWQACPELLGTRMERELRRVASGAGHTIF
EWRATPGRWHEVHAWGANGNVSIFGRDVTARKQAEAERDVLLSREHSGRLEAEALVHERTRELMAARERLVQSEKLAMAG
QLAAGVGHEINNPLSYVVGNLQFALEQLEPLATQGAVRESLARALGEAMEALREAKEGAERIRTTVRDLQIFARAEEPQL
SPVDVHAALEFGLSMAMPHLRHRARVEKRLGPVPTVMAHETRLGQVFLQLLVNAAQAIPEGDVARYQVTLSTWRDGATVV
VEVADNGHGMAPEVLERAFEPFFTTRPLGEGAGLGLSTSLGLVRGMGGELSASSAPGLGSVFQVRLPTTDADAPAVRVAE
DTDLPGRKRVLVVDDEPLLASVLGRILGVRHEVVVVHSGREALDTLARDADFDRIFCDLMMGDLTGMDVYDALSSRQPEL
LARFVFMTGGGFSERARTFLQSVPVPRIEKPFELGVLHALVEDAPPRAGP

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788549, Length=412, Percent_Identity=26.6990291262136, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI87081816, Length=363, Percent_Identity=28.099173553719, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=544, Percent_Identity=23.7132352941176, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI145693157, Length=448, Percent_Identity=25.4464285714286, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=295, Percent_Identity=23.728813559322, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790300, Length=394, Percent_Identity=25.6345177664975, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75566; Mature: 75435

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTDTDTCLPRVLVTATYSCRHGAILNDRFQAAPAPDMDVLLVALEEAERHQPEGCMVLH
CCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEHH
AVRDAAGALVDFQWAWANPAGARALGHAAPELLRGRRLRELMPGSGLASRVDLLRNVVEA
HHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
GRPAADSFQEGDVWLQGTAVPLRDGVLLRLRDITSALRLEESVRETLDWVRSMLEATPDA
CCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FFTLDADWRITFVNHEAAALSGRSQEQLFRQILWQACPELLGTRMERELRRVASGAGHTI
EEEECCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FEWRATPGRWHEVHAWGANGNVSIFGRDVTARKQAEAERDVLLSREHSGRLEAEALVHER
EEEECCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TRELMAARERLVQSEKLAMAGQLAAGVGHEINNPLSYVVGNLQFALEQLEPLATQGAVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLARALGEAMEALREAKEGAERIRTTVRDLQIFARAEEPQLSPVDVHAALEFGLSMAMPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LRHRARVEKRLGPVPTVMAHETRLGQVFLQLLVNAAQAIPEGDVARYQVTLSTWRDGATV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEE
VVEVADNGHGMAPEVLERAFEPFFTTRPLGEGAGLGLSTSLGLVRGMGGELSASSAPGLG
EEEECCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SVFQVRLPTTDADAPAVRVAEDTDLPGRKRVLVVDDEPLLASVLGRILGVRHEVVVVHSG
CEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECC
REALDTLARDADFDRIFCDLMMGDLTGMDVYDALSSRQPELLARFVFMTGGGFSERARTF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
LQSVPVPRIEKPFELGVLHALVEDAPPRAGP
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GTDTDTCLPRVLVTATYSCRHGAILNDRFQAAPAPDMDVLLVALEEAERHQPEGCMVLH
CCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEHH
AVRDAAGALVDFQWAWANPAGARALGHAAPELLRGRRLRELMPGSGLASRVDLLRNVVEA
HHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
GRPAADSFQEGDVWLQGTAVPLRDGVLLRLRDITSALRLEESVRETLDWVRSMLEATPDA
CCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FFTLDADWRITFVNHEAAALSGRSQEQLFRQILWQACPELLGTRMERELRRVASGAGHTI
EEEECCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FEWRATPGRWHEVHAWGANGNVSIFGRDVTARKQAEAERDVLLSREHSGRLEAEALVHER
EEEECCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TRELMAARERLVQSEKLAMAGQLAAGVGHEINNPLSYVVGNLQFALEQLEPLATQGAVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLARALGEAMEALREAKEGAERIRTTVRDLQIFARAEEPQLSPVDVHAALEFGLSMAMPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LRHRARVEKRLGPVPTVMAHETRLGQVFLQLLVNAAQAIPEGDVARYQVTLSTWRDGATV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEE
VVEVADNGHGMAPEVLERAFEPFFTTRPLGEGAGLGLSTSLGLVRGMGGELSASSAPGLG
EEEECCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SVFQVRLPTTDADAPAVRVAEDTDLPGRKRVLVVDDEPLLASVLGRILGVRHEVVVVHSG
CEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECC
REALDTLARDADFDRIFCDLMMGDLTGMDVYDALSSRQPELLARFVFMTGGGFSERARTF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
LQSVPVPRIEKPFELGVLHALVEDAPPRAGP
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]