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The map label for this gene is baeB [H]

Identifier: 108760697

GI number: 108760697

Start: 2899940

End: 2900596

Strand: Reverse

Name: baeB [H]

Synonym: MXAN_2490

Alternate gene names: 108760697

Gene position: 2900596-2899940 (Counterclockwise)

Preceding gene: 108761041

Following gene: 108761332

Centisome position: 31.74

GC content: 68.19

Gene sequence:

>657_bases
ATGCGTGAACCGTACGTGCGGCAGCTCAAGCTCGGGCCCATGGACAACTTCGTCTACCTGGTGGGGCCCCGGGACTCAGA
CGAGGTGGTGGTGGTGGACCCCGCGTGGGACGTGGACGCCATCGCGGAGGCGGTGAAGGCGGATGGAAAGCGCGTGGTGG
GCGCGTTCGTCTCGCACTGTCACTTCGACCACATCAACGGACTGCCCGACCTGCTGTCGATGTGGGACGTGCCCGTGTAC
GCGCAGCGGGAGGAGGTCCAGTTCTCGCCGGAGCTACGCGAGCTGGGCGGCGCGCTGCGGCCCGTGGGGCCCGGCGACGA
CGTGCGCGTGGGCTCGCAGGTGTTCCATGCGCTGCACACGCCGGGGCACACGCCGGGCTCGCACTGCCTGCTGGCTGGCG
ATGCGCTGGTCTCCGGGGACACCGTGTTCATCAACGGCTGCGGCCGGTGCGACTTGAAGGGCGGCAACCCGGAGGACATG
TACCGCTCCCTGTCCCAGGTGCTGGCGAAGGTGCCCGACACGGCGAAGCTGTTTCCGGGCCACGACTACGCGGACGTCCC
GGTGACGTCCATGGAGGCGGTGCGGAAGAAGAACCCGTACTTCGCCTTCGACAACGTGGATGCCTTCGTCGCGTTCCGAA
TGCGGCCGAGGAAGTAG

Upstream 100 bases:

>100_bases
GATCGCGAATCGTTCGTCCAGGGCCCGGAAAGAGGGAATCGGCCCGCGCCTTCAAACCCTGGACGTTAGAGTGGAGCCTG
AAGCGGAGGAGGATATCGCG

Downstream 100 bases:

>100_bases
CCGGGCCTGACATGCCGCGCGGCGGTGACCGGTGTCGAGCGTCCAACGGGCGTTCACACCGAGGTCACGTTTCCGGTGAG
TGCGTGCCTGTCTATTGAAT

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MREPYVRQLKLGPMDNFVYLVGPRDSDEVVVVDPAWDVDAIAEAVKADGKRVVGAFVSHCHFDHINGLPDLLSMWDVPVY
AQREEVQFSPELRELGGALRPVGPGDDVRVGSQVFHALHTPGHTPGSHCLLAGDALVSGDTVFINGCGRCDLKGGNPEDM
YRSLSQVLAKVPDTAKLFPGHDYADVPVTSMEAVRKKNPYFAFDNVDAFVAFRMRPRK

Sequences:

>Translated_218_residues
MREPYVRQLKLGPMDNFVYLVGPRDSDEVVVVDPAWDVDAIAEAVKADGKRVVGAFVSHCHFDHINGLPDLLSMWDVPVY
AQREEVQFSPELRELGGALRPVGPGDDVRVGSQVFHALHTPGHTPGSHCLLAGDALVSGDTVFINGCGRCDLKGGNPEDM
YRSLSQVLAKVPDTAKLFPGHDYADVPVTSMEAVRKKNPYFAFDNVDAFVAFRMRPRK
>Mature_218_residues
MREPYVRQLKLGPMDNFVYLVGPRDSDEVVVVDPAWDVDAIAEAVKADGKRVVGAFVSHCHFDHINGLPDLLSMWDVPVY
AQREEVQFSPELRELGGALRPVGPGDDVRVGSQVFHALHTPGHTPGSHCLLAGDALVSGDTVFINGCGRCDLKGGNPEDM
YRSLSQVLAKVPDTAKLFPGHDYADVPVTSMEAVRKKNPYFAFDNVDAFVAFRMRPRK

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=200, Percent_Identity=30.5, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI21703352, Length=179, Percent_Identity=36.3128491620112, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116642887, Length=179, Percent_Identity=36.3128491620112, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI14150041, Length=192, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI46361987, Length=210, Percent_Identity=30.952380952381, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI94538320, Length=178, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI94538322, Length=178, Percent_Identity=26.4044943820225, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1787158, Length=186, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786406, Length=170, Percent_Identity=28.8235294117647, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=212, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324614, Length=214, Percent_Identity=24.2990654205607, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330176, Length=209, Percent_Identity=28.7081339712919, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356335, Length=188, Percent_Identity=30.3191489361702, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667703, Length=188, Percent_Identity=30.3191489361702, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667711, Length=188, Percent_Identity=30.3191489361702, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23959; Mature: 23959

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPYVRQLKLGPMDNFVYLVGPRDSDEVVVVDPAWDVDAIAEAVKADGKRVVGAFVSHC
CCCCCCHHEECCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHH
HFDHINGLPDLLSMWDVPVYAQREEVQFSPELRELGGALRPVGPGDDVRVGSQVFHALHT
HHHHCCCHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
PGHTPGSHCLLAGDALVSGDTVFINGCGRCDLKGGNPEDMYRSLSQVLAKVPDTAKLFPG
CCCCCCCCEEEECCEEECCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCC
HDYADVPVTSMEAVRKKNPYFAFDNVDAFVAFRMRPRK
CCCCCCCCHHHHHHHHCCCEEEECCCCEEEEEEECCCC
>Mature Secondary Structure
MREPYVRQLKLGPMDNFVYLVGPRDSDEVVVVDPAWDVDAIAEAVKADGKRVVGAFVSHC
CCCCCCHHEECCCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHH
HFDHINGLPDLLSMWDVPVYAQREEVQFSPELRELGGALRPVGPGDDVRVGSQVFHALHT
HHHHCCCHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
PGHTPGSHCLLAGDALVSGDTVFINGCGRCDLKGGNPEDMYRSLSQVLAKVPDTAKLFPG
CCCCCCCCEEEECCEEECCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCC
HDYADVPVTSMEAVRKKNPYFAFDNVDAFVAFRMRPRK
CCCCCCCCHHHHHHHHCCCEEEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA