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The map label for this gene is glmM

Identifier: 108760574

GI number: 108760574

Start: 5357056

End: 5358432

Strand: Reverse

Name: glmM

Synonym: MXAN_4352

Alternate gene names: 108760574

Gene position: 5358432-5357056 (Counterclockwise)

Preceding gene: 108763537

Following gene: 108761505

Centisome position: 58.63

GC content: 67.1

Gene sequence:

>1377_bases
ATGCCTCCGAAGGAGGCGCAGGCTTCGCAGAAGCTGTTCGGCACGGATGGTGTTCGCGGGAAGGCGAACGTCTATCCCAT
GACTGCCGAGGTCGCGATGCAGCTCGGGCGGGCGCTCGCGTTCCTCATCCGCAACGGCCCGCACCGCCACCGCGTCATCG
TTGGCAAGGACACGCGGCTGTCCGGCTACATGTTGGAGCAGGCGCTGGCCTCCGGCCTCACCTCCATGGGCGTGGACGTG
GAGCTCGTCGGGCCGCTGCCGACCCCGGGCATCTCCAACATCACCACCTCCATGCGGGCGGACGCGGGCGCCGTCATCTC
CGCGTCCCACAACCCCTACGAGGACAACGGCATCAAGTTCTTCTGGCGCGACGGTTTCAAGCTGCCGGACGAGACGGAAG
GCAAGATTGAGGAGCTGGTGTCCAGCGGCTCCATCGACTCCATCCGGCCCACGGCCACGAAGATTGGCCGGGCCTTCCGC
ATGGAGGACGCGCGGGGCCGCTACATCGTCTTCCTGAAGGCCACCTTCCCGCGCGAGCTGACGCTGGAGGGGATGACCAT
CGTCGTCGACTGCGCCAACGGCGCGGCCTACAAGACGGCGCCCGCCGTGCTGGAGGAGCTGGGCGCCAAGGTGATTGCGC
TCGGCGTTTCGCCGGACGGCAAGAACATCAACCACAAGTGTGGCGCCCTCTATCCGGAGAACCTGGCCAAGACGGTGGTG
AAGCACGGCGCGCACCTGGGCATCGCCCTGGACGGTGACGCCGACCGCCTCATCGTCGTGGACGAGAAGGGCAAGGTCGT
CGACGGCGACGCCATCATGGCCATCTGCACGGGCGAGCTGGTGGCCCGCAAGCAACTGAAGAAGAAGATGTTGGTCTCCA
CGGTGATGAGCAACATCGGCCTGGAGCGCGCGGTGGCGCGCTGGGGCGTGAAGGTGGCTCGCACGCGCGTGGGTGACCGC
TACGTCGTCGATGAGATGCGCCGCAATGGCTACAACCTGGGCGGCGAGCAGAGCGGCCACCTCATCTTCCTGGATCACAC
CACCACGGGTGACGGAACCCTGGCGGCGCTCCAGTTGCTGGCGGTGATGTGCCGGGCGGGCAAGCCCCTGAGCGAGCTGG
CCTCCATCTTCGAGCCCGTGCCCCAGACGCTGGTCAACGTCGTCGTGAAGCAGAAGAAGGAGCTGGGCGAGCTCCCGACG
GTGATGAAGGTCATCAAGAGCGTGGAGCAGCGGCTGGGCAACACCGGCCGGGTGCTGGTGCGCTTCTCTGGCACCGAGCC
CAAGGCCCGCGTCCTCATCGAGGGCGAGGACGCCGCCCGCAACCAGGCCTACGCGAAGGAAATCGCGGACGCGCTGTCCA
AGGCCCTCAGCGTCTGA

Upstream 100 bases:

>100_bases
GAGCCCGCGTGGTGGGCGGGGTATAAGCCCCGACGTCGAGAGGCCGGCGCAGGCCCGGCGTGGGAAAGGCGGAGCGGCAC
ACATGGCGTACAGGATGAAC

Downstream 100 bases:

>100_bases
GGGCCGCTGCGAACGGTGGTTGACTTCCGGACGCAGCCAGCATGAAGAAGGGCCGGCGCGCACCGGGGCCTTTCGACAAT
CCCATGGCCGCGCATGAGCG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MPPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRLSGYMLEQALASGLTSMGVDV
ELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKFFWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFR
MEDARGRYIVFLKATFPRELTLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVV
KHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIGLERAVARWGVKVARTRVGDR
YVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLLAVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPT
VMKVIKSVEQRLGNTGRVLVRFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV

Sequences:

>Translated_458_residues
MPPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRLSGYMLEQALASGLTSMGVDV
ELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKFFWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFR
MEDARGRYIVFLKATFPRELTLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVV
KHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIGLERAVARWGVKVARTRVGDR
YVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLLAVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPT
VMKVIKSVEQRLGNTGRVLVRFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV
>Mature_457_residues
PPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRLSGYMLEQALASGLTSMGVDVE
LVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKFFWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFRM
EDARGRYIVFLKATFPRELTLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVVK
HGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIGLERAVARWGVKVARTRVGDRY
VVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLLAVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPTV
MKVIKSVEQRLGNTGRVLVRFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=449, Percent_Identity=49.4432071269488, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788361, Length=370, Percent_Identity=29.4594594594595, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_MYXXD (Q1D498)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_632525.1
- ProteinModelPortal:   Q1D498
- SMR:   Q1D498
- STRING:   Q1D498
- GeneID:   4104269
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4352
- TIGR:   MXAN_4352
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q1D498
- ProtClustDB:   PRK14314
- BioCyc:   MXAN246197:MXAN_4352-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49266; Mature: 49135

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRL
CCCCHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
SGYMLEQALASGLTSMGVDVELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKF
HHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCEEE
FWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFRMEDARGRYIVFLKATFPREL
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCEE
TLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVV
EECCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
KHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIG
HCCCEEEEEEECCCCEEEEECCCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
LERAVARWGVKVARTRVGDRYVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLL
HHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
AVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPTVMKVIKSVEQRLGNTGRVLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEE
RFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV
EECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRL
CCCHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
SGYMLEQALASGLTSMGVDVELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKF
HHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCCCEEE
FWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFRMEDARGRYIVFLKATFPREL
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCEE
TLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVV
EECCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
KHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIG
HCCCEEEEEEECCCCEEEEECCCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
LERAVARWGVKVARTRVGDRYVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLL
HHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
AVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPTVMKVIKSVEQRLGNTGRVLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEE
RFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV
EECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA