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The map label for this gene is pqqL [C]

Identifier: 108760533

GI number: 108760533

Start: 2425156

End: 2426520

Strand: Reverse

Name: pqqL [C]

Synonym: MXAN_2092

Alternate gene names: 108760533

Gene position: 2426520-2425156 (Counterclockwise)

Preceding gene: 108761974

Following gene: 108763039

Centisome position: 26.55

GC content: 68.5

Gene sequence:

>1365_bases
ATGAGACGACTGCTCCCCCTCCTTCTGCTCCTGCTGGGCACCGCCCTGCCGGCCGCCGCTGCCGCCCCTACCCCGGCGTC
GGACGCCTTCCCGTACACCCTCCACACGGACACCCTGCCCAACGGCCTCACCGTGGTCCGCGTGCCCTACCCGTCCCGCG
GAATCATCGCCTACGTCACCGTGGTCCGCGTCGGCTCGCGCAATGAGGTGGAACCCGGCCGCACCGGCTTCGCCCACTTC
TTCGAGCACATGATGTTCAAGGGCACGAAGACGCACCCGGAGGGCGACCGCGAGCGCATCCTCGGGAACTTCGGCTACGA
CGACAACGCCTTCACCACCGACGACATCACCCTCTACTACTCCTACGGCCCCACCGCCGGCCTGCCCCAGCTCATCGAAA
TCGAGGCGGACCGCTTCCGGAACCTGGAGTACAGCCAGCCGTCCTTCCAGACGGAGGCGCTCGCCGTGCTCGGCGAGTAC
CACAAGAACGCCGCCGCCCCCTTCCTCAAGATGGAGGAGGAGCTCAACGCCGCGGCCTTCACCCGCCACACGTACCAACA
CACCACCATGGGCTTCTACAAGGACATCCAGGCGATGCCCCAGGCCTATGACTACAGCCGCACCTTCTTCGAGCGCTGGT
ACACGCCCGACAACACCCTGCTCTTCATCATCGGCGACTTCGACGACGCCAAGGTCATGGAGCTCGTGCGCCAGCACTAC
GGCCCCTGGGACCGCAAGGCCGCCCAGGTCTCCGTCCCCGCCGAGCCGCCCCAGAAGGGCCCTCGCACCGCCCACATCGA
CTGGCCTCAGCCCACGCAGCCCCGGCAGGTGATTGCGTGGCGCACGCCCGGCGCCGGCACCAGCCCGGTCGACGCCGCCA
TCCAGACGCTCCTCGTGGACTACCTCGCCGGCCCCACCAGCCCCGCCTACAAGACGCTGGTCCTGGACAAGCAGCTCGTG
GAGTCCATTGGCAGCGACTACTCCGAGCACCGCGACCCGCACCTCTTCACCCTCACCGCCACCCTCAAGGACGAGCGCCA
CCGCAACACCGTGCGCAAGACGCTGCTCCAGGAGGTCAGCCGGCTCGCCGCCGGACGCGTGGATGCCGCGCGGCTCAAGG
CCATCCAGGACCACGCCCGCTATGGCGCGCTCATGGCCCTGGAGACGCCTCGCGACGTGGGCATCCAGCTCGGCTGGTAC
GCCGGTGTCACGGGCTCGCCCGACGGATTCCAGCGCCACCTGCAGAGCCTGCCCAAGGTGACGCCCGCCCAGTTGTCCGA
CTTCGCCAAGCGCTACCTCACCGCCAACAAGCTCATCCTGCTCAGCCTCACCCCCAAGACGGACGCCCAGGGAGGGACGA
AGTGA

Upstream 100 bases:

>100_bases
GGACACTCGGCCCACAAGCCCCTCCTCCACCGAGCCAGCCGTCGTAGGGTCGCCTACCCGCCGGGTCCCGCTTCTTCCGT
CCCGGCCACGAGGCACCTGA

Downstream 100 bases:

>100_bases
TGAAGACCCGAGCACTCCTGTCCCTCACCGCCCTGCTGGGGCTCGCCGGCTGCGCCACCACGCCCCAGGCGCCGCCTCCC
GACGAGAACGCGCCGCCGCC

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRRLLPLLLLLLGTALPAAAAAPTPASDAFPYTLHTDTLPNGLTVVRVPYPSRGIIAYVTVVRVGSRNEVEPGRTGFAHF
FEHMMFKGTKTHPEGDRERILGNFGYDDNAFTTDDITLYYSYGPTAGLPQLIEIEADRFRNLEYSQPSFQTEALAVLGEY
HKNAAAPFLKMEEELNAAAFTRHTYQHTTMGFYKDIQAMPQAYDYSRTFFERWYTPDNTLLFIIGDFDDAKVMELVRQHY
GPWDRKAAQVSVPAEPPQKGPRTAHIDWPQPTQPRQVIAWRTPGAGTSPVDAAIQTLLVDYLAGPTSPAYKTLVLDKQLV
ESIGSDYSEHRDPHLFTLTATLKDERHRNTVRKTLLQEVSRLAAGRVDAARLKAIQDHARYGALMALETPRDVGIQLGWY
AGVTGSPDGFQRHLQSLPKVTPAQLSDFAKRYLTANKLILLSLTPKTDAQGGTK

Sequences:

>Translated_454_residues
MRRLLPLLLLLLGTALPAAAAAPTPASDAFPYTLHTDTLPNGLTVVRVPYPSRGIIAYVTVVRVGSRNEVEPGRTGFAHF
FEHMMFKGTKTHPEGDRERILGNFGYDDNAFTTDDITLYYSYGPTAGLPQLIEIEADRFRNLEYSQPSFQTEALAVLGEY
HKNAAAPFLKMEEELNAAAFTRHTYQHTTMGFYKDIQAMPQAYDYSRTFFERWYTPDNTLLFIIGDFDDAKVMELVRQHY
GPWDRKAAQVSVPAEPPQKGPRTAHIDWPQPTQPRQVIAWRTPGAGTSPVDAAIQTLLVDYLAGPTSPAYKTLVLDKQLV
ESIGSDYSEHRDPHLFTLTATLKDERHRNTVRKTLLQEVSRLAAGRVDAARLKAIQDHARYGALMALETPRDVGIQLGWY
AGVTGSPDGFQRHLQSLPKVTPAQLSDFAKRYLTANKLILLSLTPKTDAQGGTK
>Mature_454_residues
MRRLLPLLLLLLGTALPAAAAAPTPASDAFPYTLHTDTLPNGLTVVRVPYPSRGIIAYVTVVRVGSRNEVEPGRTGFAHF
FEHMMFKGTKTHPEGDRERILGNFGYDDNAFTTDDITLYYSYGPTAGLPQLIEIEADRFRNLEYSQPSFQTEALAVLGEY
HKNAAAPFLKMEEELNAAAFTRHTYQHTTMGFYKDIQAMPQAYDYSRTFFERWYTPDNTLLFIIGDFDDAKVMELVRQHY
GPWDRKAAQVSVPAEPPQKGPRTAHIDWPQPTQPRQVIAWRTPGAGTSPVDAAIQTLLVDYLAGPTSPAYKTLVLDKQLV
ESIGSDYSEHRDPHLFTLTATLKDERHRNTVRKTLLQEVSRLAAGRVDAARLKAIQDHARYGALMALETPRDVGIQLGWY
AGVTGSPDGFQRHLQSLPKVTPAQLSDFAKRYLTANKLILLSLTPKTDAQGGTK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI46593007, Length=262, Percent_Identity=27.0992366412214, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787770, Length=225, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323192, Length=428, Percent_Identity=21.7289719626168, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357875, Length=152, Percent_Identity=30.2631578947368, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646943, Length=152, Percent_Identity=30.2631578947368, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 50660; Mature: 50660

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLPLLLLLLGTALPAAAAAPTPASDAFPYTLHTDTLPNGLTVVRVPYPSRGIIAYVT
CHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEE
VVRVGSRNEVEPGRTGFAHFFEHMMFKGTKTHPEGDRERILGNFGYDDNAFTTDDITLYY
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCEECCCEEEEE
SYGPTAGLPQLIEIEADRFRNLEYSQPSFQTEALAVLGEYHKNAAAPFLKMEEELNAAAF
ECCCCCCCCHHEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHH
TRHTYQHTTMGFYKDIQAMPQAYDYSRTFFERWYTPDNTLLFIIGDFDDAKVMELVRQHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHC
GPWDRKAAQVSVPAEPPQKGPRTAHIDWPQPTQPRQVIAWRTPGAGTSPVDAAIQTLLVD
CCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
YLAGPTSPAYKTLVLDKQLVESIGSDYSEHRDPHLFTLTATLKDERHRNTVRKTLLQEVS
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
RLAAGRVDAARLKAIQDHARYGALMALETPRDVGIQLGWYAGVTGSPDGFQRHLQSLPKV
HHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHCCEEEEEEECCCCCCHHHHHHHHHCCCC
TPAQLSDFAKRYLTANKLILLSLTPKTDAQGGTK
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRRLLPLLLLLLGTALPAAAAAPTPASDAFPYTLHTDTLPNGLTVVRVPYPSRGIIAYVT
CHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEE
VVRVGSRNEVEPGRTGFAHFFEHMMFKGTKTHPEGDRERILGNFGYDDNAFTTDDITLYY
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCEECCCEEEEE
SYGPTAGLPQLIEIEADRFRNLEYSQPSFQTEALAVLGEYHKNAAAPFLKMEEELNAAAF
ECCCCCCCCHHEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHH
TRHTYQHTTMGFYKDIQAMPQAYDYSRTFFERWYTPDNTLLFIIGDFDDAKVMELVRQHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHC
GPWDRKAAQVSVPAEPPQKGPRTAHIDWPQPTQPRQVIAWRTPGAGTSPVDAAIQTLLVD
CCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
YLAGPTSPAYKTLVLDKQLVESIGSDYSEHRDPHLFTLTATLKDERHRNTVRKTLLQEVS
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
RLAAGRVDAARLKAIQDHARYGALMALETPRDVGIQLGWYAGVTGSPDGFQRHLQSLPKV
HHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHCCEEEEEEECCCCCCHHHHHHHHHCCCC
TPAQLSDFAKRYLTANKLILLSLTPKTDAQGGTK
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]