Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 108760466

GI number: 108760466

Start: 6659896

End: 6660693

Strand: Reverse

Name: prpC [H]

Synonym: MXAN_5349

Alternate gene names: 108760466

Gene position: 6660693-6659896 (Counterclockwise)

Preceding gene: 108759006

Following gene: 108762233

Centisome position: 72.88

GC content: 63.16

Gene sequence:

>798_bases
GTGTCCAGCACCGCAGGGCAGACCGCGGCCTCCCGCTTGAAGATAATTTCCGCCGGCCTGACGGATGTCGGGCGCAAACG
TAATCACAACGAGGACAGCTTCCTCATTGATGATGAGCTCCAGCTCTACGTCGTGGCCGACGGAATGGGCGGCCATGCGG
GTGGCGGCACTGCGTCCCGCATCGCGGTGGAGACCATCGACAAAGAGATGCGCCGGGCGCGGGAAGGCAAGGACAACCCC
TTCCTTTCCGTCCCGAATCTCCAGGACTCTCCGATTCCGGAGGCGCTGCGCACCGCCGTGGAGCGGGCCTGTCTGGCCAT
CTTCACGGCCGCGCAGGAAGATGCGCGGCTGTCCGGCATGGGCACCACCGTCATCTCCCTGGTGGTGCGCGACGAGCACG
CCTTCTTCGCCCATGTGGGTGACAGCCGCGCATACCTCATCCGCGGTGACCTCATCCAGCAGATCTCCGAGGACCACTCG
CTGGTCAACGAGCAGATCAAAGCGGGGATGATTACCCCGGAAGAGGCGAAGCACTCCCGCTACAAGAACATCATCACCCG
CTCCGTCGGCTTCGAGGAGGAGGTGCAGGTGGACGTCATGGGGCTGGTGTCAGAGCCCGGCGACGTCTTTCTCCTCTGTT
CGGACGGCCTCGCGAACATGATGGAGGACCGGGAGATCCACGAAACCGTGGTGAAGGCGCGGACCTTCGAAGAGGTCCCC
AAGCGTCTCATCGACTTCGCGAACGAACGTGGTGGTGACGATAACATCACCGTCATCGTCGTGCGAGTGGAAGCCTGA

Upstream 100 bases:

>100_bases
GAGGGGGCCCCCCGGGGTCGGCTCCGACGCACCGCGTGAAGTGCGCCAGATTGCATCCGTGTCCTTGCCCCGTCCTTGGG
CCTCACATAGCATCCCGGGT

Downstream 100 bases:

>100_bases
CACACCCAGAGTCTGCACGTGGCCTGCAGACCTCCCTGCGGGTCTGTTGACCTTGACACTCTTCGAATGTGAGTGGTAGC
TGCCCCAACGTTTCCAGCCG

Product: serine/threonine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSSTAGQTAASRLKIISAGLTDVGRKRNHNEDSFLIDDELQLYVVADGMGGHAGGGTASRIAVETIDKEMRRAREGKDNP
FLSVPNLQDSPIPEALRTAVERACLAIFTAAQEDARLSGMGTTVISLVVRDEHAFFAHVGDSRAYLIRGDLIQQISEDHS
LVNEQIKAGMITPEEAKHSRYKNIITRSVGFEEEVQVDVMGLVSEPGDVFLLCSDGLANMMEDREIHETVVKARTFEEVP
KRLIDFANERGGDDNITVIVVRVEA

Sequences:

>Translated_265_residues
MSSTAGQTAASRLKIISAGLTDVGRKRNHNEDSFLIDDELQLYVVADGMGGHAGGGTASRIAVETIDKEMRRAREGKDNP
FLSVPNLQDSPIPEALRTAVERACLAIFTAAQEDARLSGMGTTVISLVVRDEHAFFAHVGDSRAYLIRGDLIQQISEDHS
LVNEQIKAGMITPEEAKHSRYKNIITRSVGFEEEVQVDVMGLVSEPGDVFLLCSDGLANMMEDREIHETVVKARTFEEVP
KRLIDFANERGGDDNITVIVVRVEA
>Mature_264_residues
SSTAGQTAASRLKIISAGLTDVGRKRNHNEDSFLIDDELQLYVVADGMGGHAGGGTASRIAVETIDKEMRRAREGKDNPF
LSVPNLQDSPIPEALRTAVERACLAIFTAAQEDARLSGMGTTVISLVVRDEHAFFAHVGDSRAYLIRGDLIQQISEDHSL
VNEQIKAGMITPEEAKHSRYKNIITRSVGFEEEVQVDVMGLVSEPGDVFLLCSDGLANMMEDREIHETVVKARTFEEVPK
RLIDFANERGGDDNITVIVVRVEA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29008; Mature: 28877

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTAGQTAASRLKIISAGLTDVGRKRNHNEDSFLIDDELQLYVVADGMGGHAGGGTASR
CCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCEEEEEEEECCCCCCCCCCHHH
IAVETIDKEMRRAREGKDNPFLSVPNLQDSPIPEALRTAVERACLAIFTAAQEDARLSGM
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCC
GTTVISLVVRDEHAFFAHVGDSRAYLIRGDLIQQISEDHSLVNEQIKAGMITPEEAKHSR
CHHHEEEEEECCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YKNIITRSVGFEEEVQVDVMGLVSEPGDVFLLCSDGLANMMEDREIHETVVKARTFEEVP
HHHHHHHHCCCCHHHEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KRLIDFANERGGDDNITVIVVRVEA
HHHHHHHHCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
SSTAGQTAASRLKIISAGLTDVGRKRNHNEDSFLIDDELQLYVVADGMGGHAGGGTASR
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCEEEEEEEECCCCCCCCCCHHH
IAVETIDKEMRRAREGKDNPFLSVPNLQDSPIPEALRTAVERACLAIFTAAQEDARLSGM
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCC
GTTVISLVVRDEHAFFAHVGDSRAYLIRGDLIQQISEDHSLVNEQIKAGMITPEEAKHSR
CHHHEEEEEECCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YKNIITRSVGFEEEVQVDVMGLVSEPGDVFLLCSDGLANMMEDREIHETVVKARTFEEVP
HHHHHHHHCCCCHHHEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KRLIDFANERGGDDNITVIVVRVEA
HHHHHHHHCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]