Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 108760386

GI number: 108760386

Start: 6800758

End: 6801846

Strand: Direct

Name: des [H]

Synonym: MXAN_5461

Alternate gene names: 108760386

Gene position: 6800758-6801846 (Clockwise)

Preceding gene: 108761577

Following gene: 108763887

Centisome position: 74.41

GC content: 69.05

Gene sequence:

>1089_bases
ATGCCATCTGACGCATCCACCGTTAGCGATTCTCGCGCCCAGTCCCGGGATTGGCGGGCGCGCACCCAACGGAGCGTGGT
CCAGCTCGTGGGATGCGTGGGCGCCTATGTCCTGCTCGCGGGGGCCAGCTATGTCTTCTTCGCCCAAAGCCTGGTGGGCG
GCGTGGCGCTGGCGGTGCTCGCGGGCGTCGTGCTCGTCCGGGTCTTCATCCTCCAGCACGACTGTGCCCACCGCTCGCTG
TTCCAGCGTCCGGTGACGAATGACCGGGTGGGCGTGGTGCTGGGCATGCTGACGCTGGCGCCGCACGCGTACTGGCGGGC
CATGCACCTGGTCCACCACAGCACCAGCGGAGACCTCGACCGGCGCGGCGTGGGCGACATCGTGACGATGACGGCCCAGG
AGTACCTGGCGCTCAAACCCTCCCAGCGCCTTCGCTACCGGCTGTACCGGCACCCCGCGGTCCTCCTGGGCGTGGGGCCC
ATCTTCCAGTTCCTGCTGCGCTTCCGCATGCCGGGCATCGTCGCCAAGGAGCGCAGGCCCGAGCGCCGCTCCATCCTGGT
GACGAACCTGGCGCTGGTGGCCGTCCACCTCGCGTTCCTGGCGCTGGGTGACTGGCCCCGGTGGCTGGTGGTGCACCTCA
TCATCACCCAGGTGGCCGCGGGCCTGGGCATCTGGCTCTTCTTCGTGCAGCACCAGGTGGAGCGGCCCTACTGGGTTCCG
CGGGCGCAGTGGTCCCTCAAGGGCTCGGCGCTCCAGGGCAGCAGTCACCTGGTGCTTCCACGCGCCTTCGAGTGGCTCTT
TGGCGCCATCAACCTGCACCACGTCCATCACCTGAAGCCCCAGATTCCCAACTACCTGCTGCGCGGCTACATGGAGCAGC
ACGGCCTGGCCGAAGAGGGCGTGAAGCTGGGTCTGCGCGACTCGGTGCGCGCCTTCCGCCTCAAGGTGTACGACGAGGCC
ACCGGCAGGATGACGGGCTTTCCCCCTGTCCACGCGGGCCAGGCCAGGACACCGCTGGCCTCCCCGCCCTCCATCGAGCC
GACAGGTCAGCTGGGCCGAGTGCTGACCTTCTCCGGCGAGGAACGCTGA

Upstream 100 bases:

>100_bases
CCACCACCCCGGGGCTTCTTGATTCAAGAATCAACGCGCGTTATGTCGGAAATCCCCAGATTGACAGCCCTCGGGGGAGG
TCTGGGGATTCGGGGCAGCC

Downstream 100 bases:

>100_bases
AAATGCCTGATTACGTCCATGTCCTCCTCGGACTCGTGCTGGGGTACGTCATCTCCTCGTACGTCGAGTCCTTCATGCAC
GAGTACGTGTCCGACGCGCG

Product: fatty acid desaturase family protein

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPSDASTVSDSRAQSRDWRARTQRSVVQLVGCVGAYVLLAGASYVFFAQSLVGGVALAVLAGVVLVRVFILQHDCAHRSL
FQRPVTNDRVGVVLGMLTLAPHAYWRAMHLVHHSTSGDLDRRGVGDIVTMTAQEYLALKPSQRLRYRLYRHPAVLLGVGP
IFQFLLRFRMPGIVAKERRPERRSILVTNLALVAVHLAFLALGDWPRWLVVHLIITQVAAGLGIWLFFVQHQVERPYWVP
RAQWSLKGSALQGSSHLVLPRAFEWLFGAINLHHVHHLKPQIPNYLLRGYMEQHGLAEEGVKLGLRDSVRAFRLKVYDEA
TGRMTGFPPVHAGQARTPLASPPSIEPTGQLGRVLTFSGEER

Sequences:

>Translated_362_residues
MPSDASTVSDSRAQSRDWRARTQRSVVQLVGCVGAYVLLAGASYVFFAQSLVGGVALAVLAGVVLVRVFILQHDCAHRSL
FQRPVTNDRVGVVLGMLTLAPHAYWRAMHLVHHSTSGDLDRRGVGDIVTMTAQEYLALKPSQRLRYRLYRHPAVLLGVGP
IFQFLLRFRMPGIVAKERRPERRSILVTNLALVAVHLAFLALGDWPRWLVVHLIITQVAAGLGIWLFFVQHQVERPYWVP
RAQWSLKGSALQGSSHLVLPRAFEWLFGAINLHHVHHLKPQIPNYLLRGYMEQHGLAEEGVKLGLRDSVRAFRLKVYDEA
TGRMTGFPPVHAGQARTPLASPPSIEPTGQLGRVLTFSGEER
>Mature_361_residues
PSDASTVSDSRAQSRDWRARTQRSVVQLVGCVGAYVLLAGASYVFFAQSLVGGVALAVLAGVVLVRVFILQHDCAHRSLF
QRPVTNDRVGVVLGMLTLAPHAYWRAMHLVHHSTSGDLDRRGVGDIVTMTAQEYLALKPSQRLRYRLYRHPAVLLGVGPI
FQFLLRFRMPGIVAKERRPERRSILVTNLALVAVHLAFLALGDWPRWLVVHLIITQVAAGLGIWLFFVQHQVERPYWVPR
AQWSLKGSALQGSSHLVLPRAFEWLFGAINLHHVHHLKPQIPNYLLRGYMEQHGLAEEGVKLGLRDSVRAFRLKVYDEAT
GRMTGFPPVHAGQARTPLASPPSIEPTGQLGRVLTFSGEER

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 40418; Mature: 40287

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDASTVSDSRAQSRDWRARTQRSVVQLVGCVGAYVLLAGASYVFFAQSLVGGVALAVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AGVVLVRVFILQHDCAHRSLFQRPVTNDRVGVVLGMLTLAPHAYWRAMHLVHHSTSGDLD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RRGVGDIVTMTAQEYLALKPSQRLRYRLYRHPAVLLGVGPIFQFLLRFRMPGIVAKERRP
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHCCCC
ERRSILVTNLALVAVHLAFLALGDWPRWLVVHLIITQVAAGLGIWLFFVQHQVERPYWVP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
RAQWSLKGSALQGSSHLVLPRAFEWLFGAINLHHVHHLKPQIPNYLLRGYMEQHGLAEEG
CCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHH
VKLGLRDSVRAFRLKVYDEATGRMTGFPPVHAGQARTPLASPPSIEPTGQLGRVLTFSGE
HHCCCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
ER
CC
>Mature Secondary Structure 
PSDASTVSDSRAQSRDWRARTQRSVVQLVGCVGAYVLLAGASYVFFAQSLVGGVALAVL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AGVVLVRVFILQHDCAHRSLFQRPVTNDRVGVVLGMLTLAPHAYWRAMHLVHHSTSGDLD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RRGVGDIVTMTAQEYLALKPSQRLRYRLYRHPAVLLGVGPIFQFLLRFRMPGIVAKERRP
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHCCCC
ERRSILVTNLALVAVHLAFLALGDWPRWLVVHLIITQVAAGLGIWLFFVQHQVERPYWVP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
RAQWSLKGSALQGSSHLVLPRAFEWLFGAINLHHVHHLKPQIPNYLLRGYMEQHGLAEEG
CCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHH
VKLGLRDSVRAFRLKVYDEATGRMTGFPPVHAGQARTPLASPPSIEPTGQLGRVLTFSGE
HHCCCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]