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The map label for this gene is prsA [H]

Identifier: 108760198

GI number: 108760198

Start: 532538

End: 533587

Strand: Reverse

Name: prsA [H]

Synonym: MXAN_0469

Alternate gene names: 108760198

Gene position: 533587-532538 (Counterclockwise)

Preceding gene: 108759155

Following gene: 108758581

Centisome position: 5.84

GC content: 68.0

Gene sequence:

>1050_bases
ATGACTGACGGCTTGCCAATCTGGAGCCCTCCCCCTCACGAGGCCCCGCGCATGCGCTTTTCTCCCACCCGCGCCTTCCT
GGTCCCACTCGCCATCGCCCTGGCCGCGGGGGTGGGCATGCCCGCCTGCACCAAGCCCGTGATGGAGACGCCGGAGGCCC
TGGTGGTCGCCAGCGTCAACGGCGAGGTGCTCAGCCGGGCGGACTTCGAACAGGAGCTGTGGCGCGAGCTGGCGCTGACG
GACGTGTCCCAGCGCACCTTGGAGGACGTGGAGCCCTTCAAGCGCGCGCTCCTCGATACGTACATCCACCGGATGCTGCT
GCTGCAGGAGGCGCGCAAGCACAACGTCACCGTCACCCCGGAGGAGGTGGACCGGGGGGTGCTGCGGCTGTCCGGGGACT
ATCCGGCGGGCAACTTCAACGAGGTCCTGGCCCAGGGGCAGCTCTCCATGGCGGAGCTGCGCTCGCGGGAAGCAAGCCGG
CTGACCATCGAAAAGCTGTTCGCCAGCCACGTCTATTCGCGCGTGGCGGTGACGGAAGAAGAACTGCGGGCCTGGTACGG
CGCGCACGAGAAGGACTTCCACGAGCCCGAGCAGGTCCACGCCGCGCAAATCGTGGTGAAGGGCCTGGACGAGGCACGGC
GGCTGCAAACCCAGCTCAAGTCCGGCAAGAAGTTCGCAGACCTGGCGCGCAGGTATTCGCTCAGCGCGGACGCCAAGGTG
GGAGGCGACCTGGGGTTCTTCCCCCGGGGGCAGATGCCGCCCGCCTTCGACGAAGTGGTATTCAAGCTGGGGGTGGGGCA
GGTTTCGGACGTGGTGTCCACCGAGTACGGCTTCCACCTGTTCCGCGTGCTGGAGCGCAAGCCGGCGCGCAAGCGGGAGT
TCGTGGAAGTCCGTTCGCTGGTGGAGGGCAAGCTGCTGGAGCAGAAGCGGTCGCAGGCGCAGGAGACGTTCGAACAGGAG
CTGCGGCAGAAGGCCCAGGTCCAGGTGAACGAGGCCACGTTGCAGGCCATCCGCGGGCGTCCGACGCCTCAGCAGGCGAC
GGCGGAGTGA

Upstream 100 bases:

>100_bases
CCCCTGGTGGAGGCGTTCCTCTCCGCACACGCGACGCAGCCGTAGGCCCGGTGAGGTTGTCCGGCCCTGCCCGGCGTGCT
ACCGGAACGGGCCTCGCGCC

Downstream 100 bases:

>100_bases
CGACGAAATCGAAGACCGGGGCGGCGGTTGGACGCGCCCGGGGCGGTACGGAAGGATGGCGGGAATGAAGAAGCTGGTGG
CGGCAATCGCGGCGGTGGCG

Product: putative foldase protein PrsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTDGLPIWSPPPHEAPRMRFSPTRAFLVPLAIALAAGVGMPACTKPVMETPEALVVASVNGEVLSRADFEQELWRELALT
DVSQRTLEDVEPFKRALLDTYIHRMLLLQEARKHNVTVTPEEVDRGVLRLSGDYPAGNFNEVLAQGQLSMAELRSREASR
LTIEKLFASHVYSRVAVTEEELRAWYGAHEKDFHEPEQVHAAQIVVKGLDEARRLQTQLKSGKKFADLARRYSLSADAKV
GGDLGFFPRGQMPPAFDEVVFKLGVGQVSDVVSTEYGFHLFRVLERKPARKREFVEVRSLVEGKLLEQKRSQAQETFEQE
LRQKAQVQVNEATLQAIRGRPTPQQATAE

Sequences:

>Translated_349_residues
MTDGLPIWSPPPHEAPRMRFSPTRAFLVPLAIALAAGVGMPACTKPVMETPEALVVASVNGEVLSRADFEQELWRELALT
DVSQRTLEDVEPFKRALLDTYIHRMLLLQEARKHNVTVTPEEVDRGVLRLSGDYPAGNFNEVLAQGQLSMAELRSREASR
LTIEKLFASHVYSRVAVTEEELRAWYGAHEKDFHEPEQVHAAQIVVKGLDEARRLQTQLKSGKKFADLARRYSLSADAKV
GGDLGFFPRGQMPPAFDEVVFKLGVGQVSDVVSTEYGFHLFRVLERKPARKREFVEVRSLVEGKLLEQKRSQAQETFEQE
LRQKAQVQVNEATLQAIRGRPTPQQATAE
>Mature_348_residues
TDGLPIWSPPPHEAPRMRFSPTRAFLVPLAIALAAGVGMPACTKPVMETPEALVVASVNGEVLSRADFEQELWRELALTD
VSQRTLEDVEPFKRALLDTYIHRMLLLQEARKHNVTVTPEEVDRGVLRLSGDYPAGNFNEVLAQGQLSMAELRSREASRL
TIEKLFASHVYSRVAVTEEELRAWYGAHEKDFHEPEQVHAAQIVVKGLDEARRLQTQLKSGKKFADLARRYSLSADAKVG
GDLGFFPRGQMPPAFDEVVFKLGVGQVSDVVSTEYGFHLFRVLERKPARKREFVEVRSLVEGKLLEQKRSQAQETFEQEL
RQKAQVQVNEATLQAIRGRPTPQQATAE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=86, Percent_Identity=43.0232558139535, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786645, Length=150, Percent_Identity=27.3333333333333, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 39223; Mature: 39092

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGLPIWSPPPHEAPRMRFSPTRAFLVPLAIALAAGVGMPACTKPVMETPEALVVASVN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECC
GEVLSRADFEQELWRELALTDVSQRTLEDVEPFKRALLDTYIHRMLLLQEARKHNVTVTP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECH
EEVDRGVLRLSGDYPAGNFNEVLAQGQLSMAELRSREASRLTIEKLFASHVYSRVAVTEE
HHHCCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRAWYGAHEKDFHEPEQVHAAQIVVKGLDEARRLQTQLKSGKKFADLARRYSLSADAKV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
GGDLGFFPRGQMPPAFDEVVFKLGVGQVSDVVSTEYGFHLFRVLERKPARKREFVEVRSL
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VEGKLLEQKRSQAQETFEQELRQKAQVQVNEATLQAIRGRPTPQQATAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TDGLPIWSPPPHEAPRMRFSPTRAFLVPLAIALAAGVGMPACTKPVMETPEALVVASVN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECC
GEVLSRADFEQELWRELALTDVSQRTLEDVEPFKRALLDTYIHRMLLLQEARKHNVTVTP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECH
EEVDRGVLRLSGDYPAGNFNEVLAQGQLSMAELRSREASRLTIEKLFASHVYSRVAVTEE
HHHCCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRAWYGAHEKDFHEPEQVHAAQIVVKGLDEARRLQTQLKSGKKFADLARRYSLSADAKV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
GGDLGFFPRGQMPPAFDEVVFKLGVGQVSDVVSTEYGFHLFRVLERKPARKREFVEVRSL
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VEGKLLEQKRSQAQETFEQELRQKAQVQVNEATLQAIRGRPTPQQATAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]