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The map label for this gene is qor [C]

Identifier: 108760138

GI number: 108760138

Start: 2582611

End: 2583564

Strand: Direct

Name: qor [C]

Synonym: MXAN_2240

Alternate gene names: 108760138

Gene position: 2582611-2583564 (Clockwise)

Preceding gene: 108760931

Following gene: 108760067

Centisome position: 28.26

GC content: 68.87

Gene sequence:

>954_bases
ATGAAGGCCGCCGCCATCGACCGCTTCGGTGGGCCGGAGGTGCTTGGGGTGAAGACGGTGGCCGTTCCGGTCGTAGGCGC
GGGAGAGGTGCTCATCCAAGTGGAGACCGCGGGCGTCGGAAGCTGGGATGCGGCGGAGCGCGAGGGGGAAATGGAGCTGC
TCAAGCCTCGAAAGTCATCCTTCCCCTATGTGCTGGGAACGGACGGGGCCGGCACCATCATGGCGGTGGGCGAGGGCGTC
ACGTCCCGCAAGGTGGGCGACCGGGTGTACGGCTCCGGCTTCCTCAATGACAAGGGCGGGTTCTTCGCCGAGTACGCGGT
GGTGAAGGCCGATGACACGGCGCTCGTGCCGAAGGGCTTGAGCGCGGAACAGGCGGGCGTCCTGGCCGCGGATGGAATCA
CGGCGCTCCAAGGTGTGCAGGACGCGCTGAACGTTCGTCAGGGCATGTCGCTGCTGGTGTACGGCGCGAGCGGCGGTGTG
GGCCATCTGGCGGTGCAGCTCGCCAGGCGACTGGGCGCGCGGGTCCTGGCGGTGGCTTCGGGCTCGGACGGCGTGGAGTT
GGTGAAACGCCTGGGGGCGGAGAAGGCGGTGGACGGACGGGGTGGTGATGACGTGGCGAAGGCGATTCGGGACTTCGCGC
CGGACGGGCTCGACGCGGCGCTGGTACTCGCGGGCGGCGAGGGCAGGGCCCCGGCGCTGCAAGCCGTGAAGAAGGGGGGC
CACATCGCCTACCCGAATGGCGTCGAACCGGAACCACGGGCTCCCGAGGGTGTGAAGCTCACCGCGTACAATGGCGAGTC
GAATGCTGACGTCCTCGCGCGCCTCAACCGGCTCATTGAAGCAGGGCCCTTCCATGTCGAGGTCTTCCAGGTGTACCGGC
TAGACGACGCGGGCCGCGCGCTCGAAGCCGCGCGCAAGCACCATCTGGGCAAGCTGGCCCTGCGCATCCACTGA

Upstream 100 bases:

>100_bases
GCATTCCGCGGGAGTCGTGCCCACGCTCCGGAAGAACCCTGTCGGGGCGTGAGCTCCCCGCCCGCGAGGACTCTCCATGA
AGACATCTATTCCGTCGCAG

Downstream 100 bases:

>100_bases
GCCACCGCGCGCCACGCCAGGACGCTGGCGTGGGCTTCGCGGCCGCCGCCGCTGGAGCCGGGCGGAGGGGCCTGTCCGAG
GTTAGACTCCGCGGATGAAC

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKAAAIDRFGGPEVLGVKTVAVPVVGAGEVLIQVETAGVGSWDAAEREGEMELLKPRKSSFPYVLGTDGAGTIMAVGEGV
TSRKVGDRVYGSGFLNDKGGFFAEYAVVKADDTALVPKGLSAEQAGVLAADGITALQGVQDALNVRQGMSLLVYGASGGV
GHLAVQLARRLGARVLAVASGSDGVELVKRLGAEKAVDGRGGDDVAKAIRDFAPDGLDAALVLAGGEGRAPALQAVKKGG
HIAYPNGVEPEPRAPEGVKLTAYNGESNADVLARLNRLIEAGPFHVEVFQVYRLDDAGRALEAARKHHLGKLALRIH

Sequences:

>Translated_317_residues
MKAAAIDRFGGPEVLGVKTVAVPVVGAGEVLIQVETAGVGSWDAAEREGEMELLKPRKSSFPYVLGTDGAGTIMAVGEGV
TSRKVGDRVYGSGFLNDKGGFFAEYAVVKADDTALVPKGLSAEQAGVLAADGITALQGVQDALNVRQGMSLLVYGASGGV
GHLAVQLARRLGARVLAVASGSDGVELVKRLGAEKAVDGRGGDDVAKAIRDFAPDGLDAALVLAGGEGRAPALQAVKKGG
HIAYPNGVEPEPRAPEGVKLTAYNGESNADVLARLNRLIEAGPFHVEVFQVYRLDDAGRALEAARKHHLGKLALRIH
>Mature_317_residues
MKAAAIDRFGGPEVLGVKTVAVPVVGAGEVLIQVETAGVGSWDAAEREGEMELLKPRKSSFPYVLGTDGAGTIMAVGEGV
TSRKVGDRVYGSGFLNDKGGFFAEYAVVKADDTALVPKGLSAEQAGVLAADGITALQGVQDALNVRQGMSLLVYGASGGV
GHLAVQLARRLGARVLAVASGSDGVELVKRLGAEKAVDGRGGDDVAKAIRDFAPDGLDAALVLAGGEGRAPALQAVKKGG
HIAYPNGVEPEPRAPEGVKLTAYNGESNADVLARLNRLIEAGPFHVEVFQVYRLDDAGRALEAARKHHLGKLALRIH

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=243, Percent_Identity=32.0987654320988, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI13236495, Length=243, Percent_Identity=32.0987654320988, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI194239676, Length=201, Percent_Identity=35.8208955223881, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI47519420, Length=266, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI18379349, Length=215, Percent_Identity=32.5581395348837, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI22538446, Length=214, Percent_Identity=30.8411214953271, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI22538444, Length=214, Percent_Identity=30.8411214953271, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI24308257, Length=237, Percent_Identity=28.6919831223629, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI28557745, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=203, Percent_Identity=31.5270935960591, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789651, Length=249, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082125, Length=274, Percent_Identity=27.007299270073, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=225, Percent_Identity=34.2222222222222, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988145, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=267, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=27.5449101796407, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=219, Percent_Identity=32.8767123287671, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=222, Percent_Identity=31.5315315315315, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=220, Percent_Identity=31.3636363636364, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=223, Percent_Identity=30.4932735426009, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 32688; Mature: 32688

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAAIDRFGGPEVLGVKTVAVPVVGAGEVLIQVETAGVGSWDAAEREGEMELLKPRKSS
CCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCC
FPYVLGTDGAGTIMAVGEGVTSRKVGDRVYGSGFLNDKGGFFAEYAVVKADDTALVPKGL
CCEEEECCCCCEEEEECCCCCHHHHCCHHHCCCCCCCCCCEEEEEEEEECCCCEECCCCC
SAEQAGVLAADGITALQGVQDALNVRQGMSLLVYGASGGVGHLAVQLARRLGARVLAVAS
CHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
GSDGVELVKRLGAEKAVDGRGGDDVAKAIRDFAPDGLDAALVLAGGEGRAPALQAVKKGG
CCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCC
HIAYPNGVEPEPRAPEGVKLTAYNGESNADVLARLNRLIEAGPFHVEVFQVYRLDDAGRA
CEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHH
LEAARKHHLGKLALRIH
HHHHHHHCCCEEEEEEC
>Mature Secondary Structure
MKAAAIDRFGGPEVLGVKTVAVPVVGAGEVLIQVETAGVGSWDAAEREGEMELLKPRKSS
CCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCC
FPYVLGTDGAGTIMAVGEGVTSRKVGDRVYGSGFLNDKGGFFAEYAVVKADDTALVPKGL
CCEEEECCCCCEEEEECCCCCHHHHCCHHHCCCCCCCCCCEEEEEEEEECCCCEECCCCC
SAEQAGVLAADGITALQGVQDALNVRQGMSLLVYGASGGVGHLAVQLARRLGARVLAVAS
CHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEC
GSDGVELVKRLGAEKAVDGRGGDDVAKAIRDFAPDGLDAALVLAGGEGRAPALQAVKKGG
CCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCC
HIAYPNGVEPEPRAPEGVKLTAYNGESNADVLARLNRLIEAGPFHVEVFQVYRLDDAGRA
CEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHH
LEAARKHHLGKLALRIH
HHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]