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The map label for this gene is kdpD [H]

Identifier: 108760092

GI number: 108760092

Start: 202310

End: 203479

Strand: Direct

Name: kdpD [H]

Synonym: MXAN_0167

Alternate gene names: 108760092

Gene position: 202310-203479 (Clockwise)

Preceding gene: 108762848

Following gene: 108759024

Centisome position: 2.21

GC content: 69.83

Gene sequence:

>1170_bases
ATGACGATGACGCGGCGCTCACGCGCGGAGGACTTCCTGGAGCTGGTGGAGCGGGGCAGGCGTGGCCGGCTCAAGCTCTA
CATCGGCTTCGCGGCCGGGGTGGGGAAGACGTACCGGATGCTGGAGGAGGCACACGCGCTGAAGCGGCGCGGCGTGGACG
TGGTGCTGGGCTTCGTGGAGTCGCATGACCGCGCGGACACGCAGGCGCTGGTGGAGGGCCTGGAGGTGGTGCCGCGCAAG
CAGTACTCCTACCGCGACGTTACCGTGGAGGAGATGGACCTGGACGCGGTGCTCGCGCGCAAGCCCCAGGTGGCGGTGGT
GGACGAGCTGGCTCACACCAACCTTCCGGTGTGCCGCCACCGCAAGCGCTATCAGGACGTGCAGGCGTTGCTGGACGCGG
GCATCAACGTCATCGGGGCCTTCAACGTCCAGCACCTGGAGAGCCTCAACGATTTGGTGGAGCGCGCCACCGGCGTCGCC
GTGCGGGAGACACTGCCCGACAGCTTCCTCAAGGCCGCCGACCAGGTGGTGAACCTGGACCTGGCGGTGGAGGACCTGCA
CGAGCGGCTCCGGACGGGGAAGATCTACGCGAAGGACAAGGTGCCGCGGGCGCTGGAGCGCTTCTTCACGGAGGAGAACC
TGGCCACGCTGCGCGAGCTGGCGCTGCGTGAGGTGGCGGAGAGCCTGGACCGCGCCACCGCGAGGCCGCCTCCGGGAGAG
GGAGATGAAGGTTCGCAGCGGAGCGCGGCCTGGGGCCGGGTGCTGGTGGCGCTGTCCAGTTATCCCCGGCACGCGGCGAC
GCTGATGCGCCGGGGCTCACGGATGGCGGGCCGGCTGAACACGGACTGGTTCGTCGTGTACGTGGAGACGCCGCGCGAGG
CGCCGCACCTCATCGACGCGGAGGCGCAGCGGCATCTGCTGACGAACATCGAGAAGGCGAAGGAGCTGGGCGCGGAGGTG
GTGCGCCTGAGGGCTCGAGACCCGGTGGAGGGCATCCTGGACTTCGCGCGCTCGCACGGCGTGGGTCACATCATCGTCGG
CCGTTCGCATCAGCCGTGGTGGAAGCAGCGGCTGGGGCGCGCGGTGGACATGAGGCTGGTTCGTGAAGGCCGGGGCTTCG
ACATCCACGTGGTGGCCTTCGAGCCGCGCGAGGAGGGACGCCGCCCATGA

Upstream 100 bases:

>100_bases
GGCGCACCTTGAGCGACGTGGGGGGCACGCGCATTCACCACGTGAGATTCGCCGGGCGCGAGGGCATCCTCCGCCCCGCC
TCCCACCAGATGGGCAGAGG

Downstream 100 bases:

>100_bases
CGCTGCGAGCCCGGTTGTTGTTGGCGCAGGCACCCCTGGCCCTGGCGCTGTTGTTGGTGGGCGTGGTGGCCGTGGTGACG
TTGTCCCAACTGGGGCGTTC

Product: osmosensitive K+ channel histidine kinase sensor subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTMTRRSRAEDFLELVERGRRGRLKLYIGFAAGVGKTYRMLEEAHALKRRGVDVVLGFVESHDRADTQALVEGLEVVPRK
QYSYRDVTVEEMDLDAVLARKPQVAVVDELAHTNLPVCRHRKRYQDVQALLDAGINVIGAFNVQHLESLNDLVERATGVA
VRETLPDSFLKAADQVVNLDLAVEDLHERLRTGKIYAKDKVPRALERFFTEENLATLRELALREVAESLDRATARPPPGE
GDEGSQRSAAWGRVLVALSSYPRHAATLMRRGSRMAGRLNTDWFVVYVETPREAPHLIDAEAQRHLLTNIEKAKELGAEV
VRLRARDPVEGILDFARSHGVGHIIVGRSHQPWWKQRLGRAVDMRLVREGRGFDIHVVAFEPREEGRRP

Sequences:

>Translated_389_residues
MTMTRRSRAEDFLELVERGRRGRLKLYIGFAAGVGKTYRMLEEAHALKRRGVDVVLGFVESHDRADTQALVEGLEVVPRK
QYSYRDVTVEEMDLDAVLARKPQVAVVDELAHTNLPVCRHRKRYQDVQALLDAGINVIGAFNVQHLESLNDLVERATGVA
VRETLPDSFLKAADQVVNLDLAVEDLHERLRTGKIYAKDKVPRALERFFTEENLATLRELALREVAESLDRATARPPPGE
GDEGSQRSAAWGRVLVALSSYPRHAATLMRRGSRMAGRLNTDWFVVYVETPREAPHLIDAEAQRHLLTNIEKAKELGAEV
VRLRARDPVEGILDFARSHGVGHIIVGRSHQPWWKQRLGRAVDMRLVREGRGFDIHVVAFEPREEGRRP
>Mature_388_residues
TMTRRSRAEDFLELVERGRRGRLKLYIGFAAGVGKTYRMLEEAHALKRRGVDVVLGFVESHDRADTQALVEGLEVVPRKQ
YSYRDVTVEEMDLDAVLARKPQVAVVDELAHTNLPVCRHRKRYQDVQALLDAGINVIGAFNVQHLESLNDLVERATGVAV
RETLPDSFLKAADQVVNLDLAVEDLHERLRTGKIYAKDKVPRALERFFTEENLATLRELALREVAESLDRATARPPPGEG
DEGSQRSAAWGRVLVALSSYPRHAATLMRRGSRMAGRLNTDWFVVYVETPREAPHLIDAEAQRHLLTNIEKAKELGAEVV
RLRARDPVEGILDFARSHGVGHIIVGRSHQPWWKQRLGRAVDMRLVREGRGFDIHVVAFEPREEGRRP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=355, Percent_Identity=45.0704225352113, Blast_Score=279, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44025; Mature: 43894

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTRRSRAEDFLELVERGRRGRLKLYIGFAAGVGKTYRMLEEAHALKRRGVDVVLGFVE
CCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEHHH
SHDRADTQALVEGLEVVPRKQYSYRDVTVEEMDLDAVLARKPQVAVVDELAHTNLPVCRH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCHHHHHHHHHCCCHHHHH
RKRYQDVQALLDAGINVIGAFNVQHLESLNDLVERATGVAVRETLPDSFLKAADQVVNLD
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
LAVEDLHERLRTGKIYAKDKVPRALERFFTEENLATLRELALREVAESLDRATARPPPGE
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDEGSQRSAAWGRVLVALSSYPRHAATLMRRGSRMAGRLNTDWFVVYVETPREAPHLIDA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCCCCCCH
EAQRHLLTNIEKAKELGAEVVRLRARDPVEGILDFARSHGVGHIIVGRSHQPWWKQRLGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCH
AVDMRLVREGRGFDIHVVAFEPREEGRRP
HHHHHHHHCCCCCEEEEEEECCHHCCCCC
>Mature Secondary Structure 
TMTRRSRAEDFLELVERGRRGRLKLYIGFAAGVGKTYRMLEEAHALKRRGVDVVLGFVE
CCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEHHH
SHDRADTQALVEGLEVVPRKQYSYRDVTVEEMDLDAVLARKPQVAVVDELAHTNLPVCRH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCHHHHHHHHHCCCHHHHH
RKRYQDVQALLDAGINVIGAFNVQHLESLNDLVERATGVAVRETLPDSFLKAADQVVNLD
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
LAVEDLHERLRTGKIYAKDKVPRALERFFTEENLATLRELALREVAESLDRATARPPPGE
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDEGSQRSAAWGRVLVALSSYPRHAATLMRRGSRMAGRLNTDWFVVYVETPREAPHLIDA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCCCCCCH
EAQRHLLTNIEKAKELGAEVVRLRARDPVEGILDFARSHGVGHIIVGRSHQPWWKQRLGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCH
AVDMRLVREGRGFDIHVVAFEPREEGRRP
HHHHHHHHCCCCCEEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]