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The map label for this gene is kinB [H]

Identifier: 108759024

GI number: 108759024

Start: 203476

End: 205323

Strand: Direct

Name: kinB [H]

Synonym: MXAN_0168

Alternate gene names: 108759024

Gene position: 203476-205323 (Clockwise)

Preceding gene: 108760092

Following gene: 108762423

Centisome position: 2.23

GC content: 70.94

Gene sequence:

>1848_bases
ATGACGCTGCGAGCCCGGTTGTTGTTGGCGCAGGCACCCCTGGCCCTGGCGCTGTTGTTGGTGGGCGTGGTGGCCGTGGT
GACGTTGTCCCAACTGGGGCGTTCTGGGCCTCGGGTGCTTCAGGACAACTACCGCAGTGTGCTGGCCGCGCAGGAGATGA
TGGCGCAGTTGGAGCGCATGGACAGCGGGGCGCTCTTCATCATCGCGGGTGAGCGGCAGCGCGGGCTGACGCAGCAGGCG
GCGCAGCGCGCGCGCTTGGAGTCGCAGTTGCGGGTGCAGGAAGGCAACGTCACCGAGCCCGCCGAGGATGCGGCGACGCT
CCGGTTGCGCACGTCCTGGCGGCGTTACCAGGAGGCCTATGACGGGTTCCTCGCCCAGTCGTCGCCGGAGGGGGCGCGGG
AGGCGTACTTCGGTGTTCTCGAGCCGGCCTTCCAGGAGGTGACCGGAGCGGCCCGGGCCATCCTGGACCTGAACCAGGAC
GCCATGGTGCGCAAGAGCGAGGCGTTGCAGCGGCAGAGCGCGCGGGTGAACACGGTGATGGTGGCGGCGGTGATGGTGGC
CTTCGTGGTGGGGTTGTTCGCGTCGCAGTCGCTGACGCACCGGGCGCTCCGTCCGGTGTCGGTGCTGTCACAGGCGGTGC
GGCGCCTGGGCGAGGGCGACTACGCGGCGCGCGCGGTGGTGGAGGGACAGGACGAAATCGCGCAGGTGGGGCGGGACTTC
AACGCCATGGCGGAGGCGCTTCAGCAGTACCGGCGCAGCAGCCTGGGTGAGTTGCTCCAGGCGCAGGCGGCATCACAGGC
GGCCATCGACAGCCTGCCGGACCCGGTGGTGGTGTTCGGCGCGGACGGAGGGCTGCTCAACGTCAACCGCGCGGCGGAGG
ACGTGCTGCGGCTGTCGCTCGAAGCGGGCGGGGACATGCTGGGGCAGGTGGTGCCGGAGGCGCGCGCGGTGCTGGAGCGG
GTGCGTGAGCACGTGTTGACGGGGCGAGGGGCGTATCAGCCGCGCGGGTACGAAGAGGCGGTGCGGGCGCCGCTCCCGGA
CGGGGACCGGTGGCTGCTGGCTCGGGGAAGTCCGGTGCATGGCGAGTCAGGGGAGGTGGTGGGGGCCACGGTGATTCTCC
AGGACGTGACGCGGCTGCGGCGCTTCGACGAGCTGAAGAACGACCTGGTGGCCACGGTGGCGCACGAGTTCCGCACGCCG
CTCACGTCGCTGCGCATGGCGCTGCACCTGGTGACGGAGGGCGTGGTGGGGCCGGTGACGGAGAAGCAGGCGGACCTGTT
GTTCGCGGCGCGCGAGGACTCCGAGCGGCTGCAGGGCATCGTGGATGACCTGCTGGACCTGTCGCGCATCCAGGCGGGGC
AGCTTCAGTTGGAGATTCGCCGGGTGCCGGCGGAGGAACTGGTGGACGCGGCGCTGGACGCTCAGCGGATGGCGGCGGAG
GAGCGCGGGGTCCAGGTGTCGAAGCAGGTGGGGCTGGACGTGGAGCCGGTGGACGTGGACCCGGAGCGGCTGGGGTTGGT
GCTGGGGAACCTGGTGGGCAACGCGGTGAAGCACACGCCCCCGGGAGGCGAGGTGGAGGTGCACGTGTGGCAGGAATCGC
ACGGGGTGCGCTTCGAGGTGCGCGACACGGGGGAGGGGATTGCCTTGGAGCAACAGGCGCGCATCTTCGAGAAGTTCTAC
CGGGCACCCGGCGCGCCTGCGGGAGGCGCGGGGCTGGGGCTGTCCATCGCGAAGGACATCGTCCAGGCACACGGCGGGGA
CATTGGCGTGGTGAGTACGCCCGGCCAGGGAAGCACGTTCTGGTTCACGCTGCCCCGGCGGGAAGAGTCCGGGCCGGCGA
GCGTGTGA

Upstream 100 bases:

>100_bases
AGCGGCTGGGGCGCGCGGTGGACATGAGGCTGGTTCGTGAAGGCCGGGGCTTCGACATCCACGTGGTGGCCTTCGAGCCG
CGCGAGGAGGGACGCCGCCC

Downstream 100 bases:

>100_bases
CGCGAAGGTCGTCCGTTCAGCATCGAGGACAACCCAGAGGGTGAGTCAGAGGCCTTCTGTACGGTTGGCGTGCTGTGCAC
GTGAAAAGCCAAGAACTTCG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MTLRARLLLAQAPLALALLLVGVVAVVTLSQLGRSGPRVLQDNYRSVLAAQEMMAQLERMDSGALFIIAGERQRGLTQQA
AQRARLESQLRVQEGNVTEPAEDAATLRLRTSWRRYQEAYDGFLAQSSPEGAREAYFGVLEPAFQEVTGAARAILDLNQD
AMVRKSEALQRQSARVNTVMVAAVMVAFVVGLFASQSLTHRALRPVSVLSQAVRRLGEGDYAARAVVEGQDEIAQVGRDF
NAMAEALQQYRRSSLGELLQAQAASQAAIDSLPDPVVVFGADGGLLNVNRAAEDVLRLSLEAGGDMLGQVVPEARAVLER
VREHVLTGRGAYQPRGYEEAVRAPLPDGDRWLLARGSPVHGESGEVVGATVILQDVTRLRRFDELKNDLVATVAHEFRTP
LTSLRMALHLVTEGVVGPVTEKQADLLFAAREDSERLQGIVDDLLDLSRIQAGQLQLEIRRVPAEELVDAALDAQRMAAE
ERGVQVSKQVGLDVEPVDVDPERLGLVLGNLVGNAVKHTPPGGEVEVHVWQESHGVRFEVRDTGEGIALEQQARIFEKFY
RAPGAPAGGAGLGLSIAKDIVQAHGGDIGVVSTPGQGSTFWFTLPRREESGPASV

Sequences:

>Translated_615_residues
MTLRARLLLAQAPLALALLLVGVVAVVTLSQLGRSGPRVLQDNYRSVLAAQEMMAQLERMDSGALFIIAGERQRGLTQQA
AQRARLESQLRVQEGNVTEPAEDAATLRLRTSWRRYQEAYDGFLAQSSPEGAREAYFGVLEPAFQEVTGAARAILDLNQD
AMVRKSEALQRQSARVNTVMVAAVMVAFVVGLFASQSLTHRALRPVSVLSQAVRRLGEGDYAARAVVEGQDEIAQVGRDF
NAMAEALQQYRRSSLGELLQAQAASQAAIDSLPDPVVVFGADGGLLNVNRAAEDVLRLSLEAGGDMLGQVVPEARAVLER
VREHVLTGRGAYQPRGYEEAVRAPLPDGDRWLLARGSPVHGESGEVVGATVILQDVTRLRRFDELKNDLVATVAHEFRTP
LTSLRMALHLVTEGVVGPVTEKQADLLFAAREDSERLQGIVDDLLDLSRIQAGQLQLEIRRVPAEELVDAALDAQRMAAE
ERGVQVSKQVGLDVEPVDVDPERLGLVLGNLVGNAVKHTPPGGEVEVHVWQESHGVRFEVRDTGEGIALEQQARIFEKFY
RAPGAPAGGAGLGLSIAKDIVQAHGGDIGVVSTPGQGSTFWFTLPRREESGPASV
>Mature_614_residues
TLRARLLLAQAPLALALLLVGVVAVVTLSQLGRSGPRVLQDNYRSVLAAQEMMAQLERMDSGALFIIAGERQRGLTQQAA
QRARLESQLRVQEGNVTEPAEDAATLRLRTSWRRYQEAYDGFLAQSSPEGAREAYFGVLEPAFQEVTGAARAILDLNQDA
MVRKSEALQRQSARVNTVMVAAVMVAFVVGLFASQSLTHRALRPVSVLSQAVRRLGEGDYAARAVVEGQDEIAQVGRDFN
AMAEALQQYRRSSLGELLQAQAASQAAIDSLPDPVVVFGADGGLLNVNRAAEDVLRLSLEAGGDMLGQVVPEARAVLERV
REHVLTGRGAYQPRGYEEAVRAPLPDGDRWLLARGSPVHGESGEVVGATVILQDVTRLRRFDELKNDLVATVAHEFRTPL
TSLRMALHLVTEGVVGPVTEKQADLLFAAREDSERLQGIVDDLLDLSRIQAGQLQLEIRRVPAEELVDAALDAQRMAAEE
RGVQVSKQVGLDVEPVDVDPERLGLVLGNLVGNAVKHTPPGGEVEVHVWQESHGVRFEVRDTGEGIALEQQARIFEKFYR
APGAPAGGAGLGLSIAKDIVQAHGGDIGVVSTPGQGSTFWFTLPRREESGPASV

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=366, Percent_Identity=31.4207650273224, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=27.9898218829517, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=34.051724137931, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=25.2551020408163, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI48994928, Length=444, Percent_Identity=26.3513513513513, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=33.9130434782609, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=31.1475409836066, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=32.2033898305085, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=31.6455696202532, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=32.5991189427313, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=31.7596566523605, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=32.4786324786325, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789403, Length=287, Percent_Identity=29.616724738676, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.8702928870293, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=30.2884615384615, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789808, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=30.5084745762712, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=27.3542600896861, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788279, Length=239, Percent_Identity=22.5941422594142, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66415; Mature: 66284

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRARLLLAQAPLALALLLVGVVAVVTLSQLGRSGPRVLQDNYRSVLAAQEMMAQLERM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DSGALFIIAGERQRGLTQQAAQRARLESQLRVQEGNVTEPAEDAATLRLRTSWRRYQEAY
CCCCEEEEECCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DGFLAQSSPEGAREAYFGVLEPAFQEVTGAARAILDLNQDAMVRKSEALQRQSARVNTVM
HCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VAAVMVAFVVGLFASQSLTHRALRPVSVLSQAVRRLGEGDYAARAVVEGQDEIAQVGRDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCH
NAMAEALQQYRRSSLGELLQAQAASQAAIDSLPDPVVVFGADGGLLNVNRAAEDVLRLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECHHHHHHHHHHHH
EAGGDMLGQVVPEARAVLERVREHVLTGRGAYQPRGYEEAVRAPLPDGDRWLLARGSPVH
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCC
GESGEVVGATVILQDVTRLRRFDELKNDLVATVAHEFRTPLTSLRMALHLVTEGVVGPVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
EKQADLLFAAREDSERLQGIVDDLLDLSRIQAGQLQLEIRRVPAEELVDAALDAQRMAAE
CHHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
ERGVQVSKQVGLDVEPVDVDPERLGLVLGNLVGNAVKHTPPGGEVEVHVWQESHGVRFEV
HHCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEE
RDTGEGIALEQQARIFEKFYRAPGAPAGGAGLGLSIAKDIVQAHGGDIGVVSTPGQGSTF
ECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
WFTLPRREESGPASV
EEEECCCCCCCCCCC
>Mature Secondary Structure 
TLRARLLLAQAPLALALLLVGVVAVVTLSQLGRSGPRVLQDNYRSVLAAQEMMAQLERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DSGALFIIAGERQRGLTQQAAQRARLESQLRVQEGNVTEPAEDAATLRLRTSWRRYQEAY
CCCCEEEEECCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DGFLAQSSPEGAREAYFGVLEPAFQEVTGAARAILDLNQDAMVRKSEALQRQSARVNTVM
HCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VAAVMVAFVVGLFASQSLTHRALRPVSVLSQAVRRLGEGDYAARAVVEGQDEIAQVGRDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCH
NAMAEALQQYRRSSLGELLQAQAASQAAIDSLPDPVVVFGADGGLLNVNRAAEDVLRLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECHHHHHHHHHHHH
EAGGDMLGQVVPEARAVLERVREHVLTGRGAYQPRGYEEAVRAPLPDGDRWLLARGSPVH
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCC
GESGEVVGATVILQDVTRLRRFDELKNDLVATVAHEFRTPLTSLRMALHLVTEGVVGPVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
EKQADLLFAAREDSERLQGIVDDLLDLSRIQAGQLQLEIRRVPAEELVDAALDAQRMAAE
CHHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
ERGVQVSKQVGLDVEPVDVDPERLGLVLGNLVGNAVKHTPPGGEVEVHVWQESHGVRFEV
HHCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEE
RDTGEGIALEQQARIFEKFYRAPGAPAGGAGLGLSIAKDIVQAHGGDIGVVSTPGQGSTF
ECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
WFTLPRREESGPASV
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]