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The map label for this gene is crt [H]

Identifier: 108759739

GI number: 108759739

Start: 3149390

End: 3150472

Strand: Direct

Name: crt [H]

Synonym: MXAN_2698

Alternate gene names: 108759739

Gene position: 3149390-3150472 (Clockwise)

Preceding gene: 108759222

Following gene: 108758734

Centisome position: 34.46

GC content: 71.47

Gene sequence:

>1083_bases
ATGACGGACGACCTTCTGCTCGAGACGCGTGGCGCGGTAGGCGTGGTGACCCTGAACCGGCCCAAGGCCCTGAACGCGCT
GAACCTGGGCATGTGCCGAAAGCTGCACCCGGCGCTCGACGCCTGGGCGGCGGACCCGTCCATTCAGGCCGTGGTCATCC
GGGGGGCTGGCGGCCGAGCCTTCTGCGCGGGCGGAGACGTACGCGCGGTGGCGCTGTCGGTGGGGGACGCGTCCGCTGAA
GCGAAGGAGCGGGTGTCGCGGGAGTTCTTCCGCGCCGAGTACGGGCTGAACCACCGCATCCACTACTTCGGCAAGCCGTT
CATCGCGCTGGTGGACGGGGTCTGCATGGGCGGCGGGCTGGGCCTGTCGATTCACGGCACCCACCGGGTCGTCACCGAGA
AGCTGGTGCTGGCCATGCCGGAGACGGCCATCGGGCTCTTCCCGGATGTGGGCGGCGGCTGGTTCCTGCCGCGCTTCCCG
GGTGAGTCGGGCACGTACCTGGGCCTCACGGGGGCCCGGTGCGGCGCGGCGGACGCGATGTGGCTGGGCTACGCCACGCA
CCACGTGGAGTCCGCGCGGCTGGAGGCGGTACTGGACGCGTTGGTGGGGGCGCCCTGGGGCACCGGCGCGGCGAGCACGG
TGGTGGACACGGTGCTGGCCGGCTTCCACGCGGACGCGGGCACGTCGCCACTGGGGGTGCAGCGCGCCGCCATCGACCGG
TGCTTCGCGGCCGAGCGCGTGGACGACATCCAGCAGGCGCTGGAGCTGGAGGGCACGCCGTGGGCCCAGGAGACGTGGGC
CACGTTGCTTCACATGTGCCCGGCCAGCTTGAAGGTGACGCTGCGCCAGCTCCGGATGGGGCGCACCCGCGACTACGACG
AGATGGCCAACGTGGAGTACCGGCTCAGCCAGTCGATGACGGCACGGCCGGACTTCCGTGAGGGCATCCGCGCGGTGCTC
GTGGACAAGGACAACAAGCCGCACTGGCGGCCCTCCACGCTGGCGGAAGTCACCGAAGGCATGGTGGAGGCGCTCTTCGC
GCCGCTGCTTCACGACACGTGGAAGGTTCCGGCGCGCGGGTAG

Upstream 100 bases:

>100_bases
GCGCCAGTGCGGAGGTCATGCGTTCCCCATAGCGCGTCTGCTCCCGCGGCGGGCCAATGAATCCACCCAAGGGGCTGCTC
GCCTGATATCCCCGGCCGCC

Downstream 100 bases:

>100_bases
GGGCTGTTGCTAGAGGTCCTCGTCGCTGAGGACGGTGATGTCCTTCGCGCGAAGTAGCGCCGTGGTGATGCCTTCGCCCG
CGCGGAGCTGGCCGGACTCG

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTDDLLLETRGAVGVVTLNRPKALNALNLGMCRKLHPALDAWAADPSIQAVVIRGAGGRAFCAGGDVRAVALSVGDASAE
AKERVSREFFRAEYGLNHRIHYFGKPFIALVDGVCMGGGLGLSIHGTHRVVTEKLVLAMPETAIGLFPDVGGGWFLPRFP
GESGTYLGLTGARCGAADAMWLGYATHHVESARLEAVLDALVGAPWGTGAASTVVDTVLAGFHADAGTSPLGVQRAAIDR
CFAAERVDDIQQALELEGTPWAQETWATLLHMCPASLKVTLRQLRMGRTRDYDEMANVEYRLSQSMTARPDFREGIRAVL
VDKDNKPHWRPSTLAEVTEGMVEALFAPLLHDTWKVPARG

Sequences:

>Translated_360_residues
MTDDLLLETRGAVGVVTLNRPKALNALNLGMCRKLHPALDAWAADPSIQAVVIRGAGGRAFCAGGDVRAVALSVGDASAE
AKERVSREFFRAEYGLNHRIHYFGKPFIALVDGVCMGGGLGLSIHGTHRVVTEKLVLAMPETAIGLFPDVGGGWFLPRFP
GESGTYLGLTGARCGAADAMWLGYATHHVESARLEAVLDALVGAPWGTGAASTVVDTVLAGFHADAGTSPLGVQRAAIDR
CFAAERVDDIQQALELEGTPWAQETWATLLHMCPASLKVTLRQLRMGRTRDYDEMANVEYRLSQSMTARPDFREGIRAVL
VDKDNKPHWRPSTLAEVTEGMVEALFAPLLHDTWKVPARG
>Mature_359_residues
TDDLLLETRGAVGVVTLNRPKALNALNLGMCRKLHPALDAWAADPSIQAVVIRGAGGRAFCAGGDVRAVALSVGDASAEA
KERVSREFFRAEYGLNHRIHYFGKPFIALVDGVCMGGGLGLSIHGTHRVVTEKLVLAMPETAIGLFPDVGGGWFLPRFPG
ESGTYLGLTGARCGAADAMWLGYATHHVESARLEAVLDALVGAPWGTGAASTVVDTVLAGFHADAGTSPLGVQRAAIDRC
FAAERVDDIQQALELEGTPWAQETWATLLHMCPASLKVTLRQLRMGRTRDYDEMANVEYRLSQSMTARPDFREGIRAVLV
DKDNKPHWRPSTLAEVTEGMVEALFAPLLHDTWKVPARG

Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=354, Percent_Identity=44.3502824858757, Blast_Score=311, Evalue=6e-85,
Organism=Homo sapiens, GI37594469, Length=310, Percent_Identity=43.8709677419355, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI194097323, Length=202, Percent_Identity=36.6336633663366, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI20127408, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI68989263, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI221142681, Length=195, Percent_Identity=30.2564102564103, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787659, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788682, Length=205, Percent_Identity=30.2439024390244, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=351, Percent_Identity=46.4387464387464, Blast_Score=317, Evalue=7e-87,
Organism=Caenorhabditis elegans, GI25144157, Length=351, Percent_Identity=46.4387464387464, Blast_Score=317, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI25144276, Length=160, Percent_Identity=32.5, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=160, Percent_Identity=32.5, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17508953, Length=160, Percent_Identity=32.5, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=27.9661016949153, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=28.7292817679558, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=185, Percent_Identity=30.2702702702703, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=172, Percent_Identity=34.3023255813954, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=354, Percent_Identity=33.0508474576271, Blast_Score=176, Evalue=6e-45,
Organism=Drosophila melanogaster, GI28571730, Length=338, Percent_Identity=44.0828402366864, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI28571729, Length=338, Percent_Identity=44.0828402366864, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI20129971, Length=185, Percent_Identity=35.6756756756757, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653477, Length=185, Percent_Identity=35.6756756756757, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653139, Length=229, Percent_Identity=27.9475982532751, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 38708; Mature: 38577

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDLLLETRGAVGVVTLNRPKALNALNLGMCRKLHPALDAWAADPSIQAVVIRGAGGRA
CCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
FCAGGDVRAVALSVGDASAEAKERVSREFFRAEYGLNHRIHYFGKPFIALVDGVCMGGGL
EECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCC
GLSIHGTHRVVTEKLVLAMPETAIGLFPDVGGGWFLPRFPGESGTYLGLTGARCGAADAM
EEEECCCHHHHHHHHHHHCCCHHHCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCHHH
WLGYATHHVESARLEAVLDALVGAPWGTGAASTVVDTVLAGFHADAGTSPLGVQRAAIDR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
CFAAERVDDIQQALELEGTPWAQETWATLLHMCPASLKVTLRQLRMGRTRDYDEMANVEY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCHH
RLSQSMTARPDFREGIRAVLVDKDNKPHWRPSTLAEVTEGMVEALFAPLLHDTWKVPARG
HHCCCCCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDDLLLETRGAVGVVTLNRPKALNALNLGMCRKLHPALDAWAADPSIQAVVIRGAGGRA
CCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
FCAGGDVRAVALSVGDASAEAKERVSREFFRAEYGLNHRIHYFGKPFIALVDGVCMGGGL
EECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCC
GLSIHGTHRVVTEKLVLAMPETAIGLFPDVGGGWFLPRFPGESGTYLGLTGARCGAADAM
EEEECCCHHHHHHHHHHHCCCHHHCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCHHH
WLGYATHHVESARLEAVLDALVGAPWGTGAASTVVDTVLAGFHADAGTSPLGVQRAAIDR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
CFAAERVDDIQQALELEGTPWAQETWATLLHMCPASLKVTLRQLRMGRTRDYDEMANVEY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHCCHH
RLSQSMTARPDFREGIRAVLVDKDNKPHWRPSTLAEVTEGMVEALFAPLLHDTWKVPARG
HHCCCCCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]