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The map label for this gene is gatA

Identifier: 108759562

GI number: 108759562

Start: 1722431

End: 1723891

Strand: Direct

Name: gatA

Synonym: MXAN_1463

Alternate gene names: 108759562

Gene position: 1722431-1723891 (Clockwise)

Preceding gene: 108757153

Following gene: 108759569

Centisome position: 18.85

GC content: 71.32

Gene sequence:

>1461_bases
ATGCAGCTCACGGACCTCACGATGCTGGAGCTGGCCGCGAAGCTGGCCGCGGGAGAGGCCTCCTCCGAGGAGGCCACCCG
CGCGAGCCTGGCGCGCATCCAGCAGGTGGACCCGAAGGTGCGCGCCTTCTTGCGCGTGGATGAAGCCGGTGCCCTGGCCG
CCGCTCGCGCCAGTGACGCGCGCCGCAAGTCGGGCAGTCCCGCCAGCGCCCTGGACGGCGTGCCGTTGGGGCTCAAGGAC
ATCTTCCTCACCGAGGGCGTGGAGACCACCGCCGGCTCGCGCATCCTGGAGGGCTTCGTTCCGCCCTATGACGCCACGGT
GGTGCGCCTGCTGAAGGAGGCGGGCCTGCCGCTGGTGGGCAAGCTGAACATGGATGAGTTCGCGATGGGCTCATCCAACG
AATCCAGCGCCTTCTTCCCCAGCCACAACCCGTGGGATGTGTCGCGCACGCCGGGCGGCTCGTCTGGTGGCTCGGCGGCG
GCGGTGGCCGCGCGCGAGGTGTTCGGCGCGCTGGGAACGGACACGGGCGGCTCCATCCGCCAGCCCGCGGCGCTCACCAA
CACCGTGGGGCTGAAGCCCACCTACGGCCGGGTGTCGCGCTTTGGCGTCATCGCCTTCGCCTCGTCGCTGGACCAGCCGG
GCCCCATGACGCGCACGGTGGCGGACGCGGCGGCGCTGCTCCAGGTGATTGCGCGGCCGGACGCGCAGGACGCCACGTCC
GCGGACGCGCCCGTGCCGGATTATTCGGCGGACCTGGAGGCCGGCGTGCGGGGCCTGAAGCTGGGCGTTCCGCGCGAGTA
CTTCACCGAGGGCATGGACCCGGAGGTGGAGGCCGCGGTGCGCGAGGCCCTGCGCGAGTACGAGCGTCTGGGCGCGACGC
TGGTGGACGTGTCGCTGCCCCACACGAAGTACGCGCTGGCGACGTACTACCTCATCGCGCCCGCGGAGGCGTCCAGCAAC
CTGGCTCGCTACGATGGCGTGCGCTTCGGCCTGCGGGCGAAGGACGCGCGCAGCCTGCGGGACGTGTACGCGCTGACGCG
GGAGCAGGGCTTCGGCGCGGAGGTGAAGCGCCGCATCATGCTGGGGACCTTCGCGCTGTCCTCCGGCTACTACGACGCCC
ACTACCTGCGTGCGCAGAAGGTTCGCACGCTCATCCGCGAGGACTTCACGCGGGCCTTCCAGCAGGTGGACGCGCTGCTG
TCGCCCACCTCGCCGGTGCCGGCCTTCAAGCTGGGTGAGAAGGTCGAGGACCCGCTGTCCATGTACCTCATGGACATCTA
CACGCTGCCTTGCAACCTGGCGGGCCTGCCCGGCCTGTCGGTGCCCTGCGGCTTCACGAAGGCGGGCTTGCCCGTGGGCC
TGCAGATTCTGGGGCGGCCCTTCGACGAGGCTGGCCTGCTGCGCATTGCCCGCGCCTACGAGCGCGAGCACGACTTCTTC
CGCCGCTCCGCGCCCCTGTAG

Upstream 100 bases:

>100_bases
GTCCCTGCCGCCAGAGAAGTCCCTGGCCAACGCGCCGGCGAAGTCGGACACGTCCTTCGCCGTGCCGAAAATCATCGAGT
AGCCCCGGAGGTTCCACGCC

Downstream 100 bases:

>100_bases
GGCCCTCGAGCGTCCGCCCTGGTGACACCGCCATGCCCGTGAGCGATTTCCAGCCCGTCATCGGCCTCGAGGTCCACGCG
CAGCTCCTCACGCAGTCCAA

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MQLTDLTMLELAAKLAAGEASSEEATRASLARIQQVDPKVRAFLRVDEAGALAAARASDARRKSGSPASALDGVPLGLKD
IFLTEGVETTAGSRILEGFVPPYDATVVRLLKEAGLPLVGKLNMDEFAMGSSNESSAFFPSHNPWDVSRTPGGSSGGSAA
AVAAREVFGALGTDTGGSIRQPAALTNTVGLKPTYGRVSRFGVIAFASSLDQPGPMTRTVADAAALLQVIARPDAQDATS
ADAPVPDYSADLEAGVRGLKLGVPREYFTEGMDPEVEAAVREALREYERLGATLVDVSLPHTKYALATYYLIAPAEASSN
LARYDGVRFGLRAKDARSLRDVYALTREQGFGAEVKRRIMLGTFALSSGYYDAHYLRAQKVRTLIREDFTRAFQQVDALL
SPTSPVPAFKLGEKVEDPLSMYLMDIYTLPCNLAGLPGLSVPCGFTKAGLPVGLQILGRPFDEAGLLRIARAYEREHDFF
RRSAPL

Sequences:

>Translated_486_residues
MQLTDLTMLELAAKLAAGEASSEEATRASLARIQQVDPKVRAFLRVDEAGALAAARASDARRKSGSPASALDGVPLGLKD
IFLTEGVETTAGSRILEGFVPPYDATVVRLLKEAGLPLVGKLNMDEFAMGSSNESSAFFPSHNPWDVSRTPGGSSGGSAA
AVAAREVFGALGTDTGGSIRQPAALTNTVGLKPTYGRVSRFGVIAFASSLDQPGPMTRTVADAAALLQVIARPDAQDATS
ADAPVPDYSADLEAGVRGLKLGVPREYFTEGMDPEVEAAVREALREYERLGATLVDVSLPHTKYALATYYLIAPAEASSN
LARYDGVRFGLRAKDARSLRDVYALTREQGFGAEVKRRIMLGTFALSSGYYDAHYLRAQKVRTLIREDFTRAFQQVDALL
SPTSPVPAFKLGEKVEDPLSMYLMDIYTLPCNLAGLPGLSVPCGFTKAGLPVGLQILGRPFDEAGLLRIARAYEREHDFF
RRSAPL
>Mature_486_residues
MQLTDLTMLELAAKLAAGEASSEEATRASLARIQQVDPKVRAFLRVDEAGALAAARASDARRKSGSPASALDGVPLGLKD
IFLTEGVETTAGSRILEGFVPPYDATVVRLLKEAGLPLVGKLNMDEFAMGSSNESSAFFPSHNPWDVSRTPGGSSGGSAA
AVAAREVFGALGTDTGGSIRQPAALTNTVGLKPTYGRVSRFGVIAFASSLDQPGPMTRTVADAAALLQVIARPDAQDATS
ADAPVPDYSADLEAGVRGLKLGVPREYFTEGMDPEVEAAVREALREYERLGATLVDVSLPHTKYALATYYLIAPAEASSN
LARYDGVRFGLRAKDARSLRDVYALTREQGFGAEVKRRIMLGTFALSSGYYDAHYLRAQKVRTLIREDFTRAFQQVDALL
SPTSPVPAFKLGEKVEDPLSMYLMDIYTLPCNLAGLPGLSVPCGFTKAGLPVGLQILGRPFDEAGLLRIARAYEREHDFF
RRSAPL

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family

Homologues:

Organism=Homo sapiens, GI222831590, Length=497, Percent_Identity=38.0281690140845, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI195972892, Length=491, Percent_Identity=25.2545824847251, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI166795287, Length=249, Percent_Identity=31.7269076305221, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543272, Length=444, Percent_Identity=36.036036036036, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17537465, Length=503, Percent_Identity=25.2485089463221, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17556264, Length=236, Percent_Identity=31.3559322033898, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538252, Length=521, Percent_Identity=23.9923224568138, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990152, Length=472, Percent_Identity=23.5169491525424, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=521, Percent_Identity=25.5278310940499, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556276, Length=309, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556278, Length=309, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323950, Length=468, Percent_Identity=34.8290598290598, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6319685, Length=415, Percent_Identity=30.1204819277108, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320448, Length=525, Percent_Identity=24.3809523809524, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648113, Length=492, Percent_Identity=39.2276422764228, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24652985, Length=504, Percent_Identity=27.1825396825397, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922090, Length=504, Percent_Identity=27.1825396825397, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652981, Length=504, Percent_Identity=27.1825396825397, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652983, Length=504, Percent_Identity=27.1825396825397, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644968, Length=495, Percent_Identity=25.8585858585859, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161078093, Length=510, Percent_Identity=27.0588235294118, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356731, Length=492, Percent_Identity=25.4065040650407, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648435, Length=512, Percent_Identity=22.8515625, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648437, Length=512, Percent_Identity=22.8515625, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550774, Length=512, Percent_Identity=22.8515625, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648441, Length=443, Percent_Identity=22.7990970654628, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648439, Length=443, Percent_Identity=22.7990970654628, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATA_MYXXD (Q1DCA3)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629720.1
- ProteinModelPortal:   Q1DCA3
- SMR:   Q1DCA3
- STRING:   Q1DCA3
- GeneID:   4103566
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1463
- TIGR:   MXAN_1463
- eggNOG:   COG0154
- HOGENOM:   HBG481888
- OMA:   RWGLIAF
- PhylomeDB:   Q1DCA3
- ProtClustDB:   PRK00012
- BioCyc:   MXAN246197:MXAN_1463-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_00120
- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412
- Gene3D:   G3DSA:3.90.1300.10
- PANTHER:   PTHR11895
- TIGRFAMs:   TIGR00132

Pfam domain/function: PF01425 Amidase; SSF75304 Amidase_sig_enz

EC number: 6.3.5.-

Molecular weight: Translated: 51955; Mature: 51955

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00571 AMIDASES

Important sites: ACT_SITE 79-79 ACT_SITE 154-154 ACT_SITE 178-178

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTDLTMLELAAKLAAGEASSEEATRASLARIQQVDPKVRAFLRVDEAGALAAARASDA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHEECCCCCHHHHHHHHH
RRKSGSPASALDGVPLGLKDIFLTEGVETTAGSRILEGFVPPYDATVVRLLKEAGLPLVG
HHCCCCCCHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
KLNMDEFAMGSSNESSAFFPSHNPWDVSRTPGGSSGGSAAAVAAREVFGALGTDTGGSIR
ECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
QPAALTNTVGLKPTYGRVSRFGVIAFASSLDQPGPMTRTVADAAALLQVIARPDAQDATS
CCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
ADAPVPDYSADLEAGVRGLKLGVPREYFTEGMDPEVEAAVREALREYERLGATLVDVSLP
CCCCCCCCCCCHHHCCCCEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECCC
HTKYALATYYLIAPAEASSNLARYDGVRFGLRAKDARSLRDVYALTREQGFGAEVKRRIM
CHHHHHEEEEEEECCCCCCCHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGTFALSSGYYDAHYLRAQKVRTLIREDFTRAFQQVDALLSPTSPVPAFKLGEKVEDPLS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHH
MYLMDIYTLPCNLAGLPGLSVPCGFTKAGLPVGLQILGRPFDEAGLLRIARAYEREHDFF
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RRSAPL
HHCCCC
>Mature Secondary Structure
MQLTDLTMLELAAKLAAGEASSEEATRASLARIQQVDPKVRAFLRVDEAGALAAARASDA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHEECCCCCHHHHHHHHH
RRKSGSPASALDGVPLGLKDIFLTEGVETTAGSRILEGFVPPYDATVVRLLKEAGLPLVG
HHCCCCCCHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
KLNMDEFAMGSSNESSAFFPSHNPWDVSRTPGGSSGGSAAAVAAREVFGALGTDTGGSIR
ECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
QPAALTNTVGLKPTYGRVSRFGVIAFASSLDQPGPMTRTVADAAALLQVIARPDAQDATS
CCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
ADAPVPDYSADLEAGVRGLKLGVPREYFTEGMDPEVEAAVREALREYERLGATLVDVSLP
CCCCCCCCCCCHHHCCCCEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECCC
HTKYALATYYLIAPAEASSNLARYDGVRFGLRAKDARSLRDVYALTREQGFGAEVKRRIM
CHHHHHEEEEEEECCCCCCCHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGTFALSSGYYDAHYLRAQKVRTLIREDFTRAFQQVDALLSPTSPVPAFKLGEKVEDPLS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHH
MYLMDIYTLPCNLAGLPGLSVPCGFTKAGLPVGLQILGRPFDEAGLLRIARAYEREHDFF
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
RRSAPL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA