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The map label for this gene is udg [H]

Identifier: 108759401

GI number: 108759401

Start: 1225710

End: 1227008

Strand: Direct

Name: udg [H]

Synonym: MXAN_1048

Alternate gene names: 108759401

Gene position: 1225710-1227008 (Clockwise)

Preceding gene: 108758608

Following gene: 108760012

Centisome position: 13.41

GC content: 66.44

Gene sequence:

>1299_bases
ATGCGTATTGCCATCATCGGAACCGGCTACGTCGGACTGGTCGCGGGCACCTGTTTCGCGGACTCGGGTAACGACGTCAC
GTGCGTGGACATCGACGAGCGGAAGATCCGCATGCTCCAGGCGGGCGAGGTGCCCATCTACGAGCCCGGCCTGGAGGAGC
TCATCAAGAAGAACGTGCGCGAGAAGCGCCTGTTCTTCACCCGGGACCTGACGGAGGCCGTCACCAACGCCCAGGTCGTC
TTCATCGCCGTGGGCACGCCGGAAGGTGAGAGCGGCGACGCCGACCTCCAGTACGTGCTGGCCGCCGCCGAGCAGATTGG
CAAGGCGATGAAGCAGTACACGGTGGTGGTGGACAAGAGCACCGTGCCGGTGGGCACCGCGGACAAGGTGCGCGAGGCCA
TCCGCAAGGTGACGGACATCGAGTTCGACGTCGTCTCCAACCCGGAGTTCCTCAAGGAAGGCGCCGCGCTGGACGACTTC
CTCAAGCCCGACCGCGTCGTCATTGGCGTGGACTCCGAGCGCGCCCGCAAGGTGATGGCGGACCTGTACTCGCCCTTTGT
GCGCACCGAGAACCCGGTGTTGTTCATGGACACGCGCTCGGCGGAGCTGACGAAGTACGCGGCCAACGCGATGCTGGCCA
CGCGCATCTCCTTCATGAACGACATCGCCGCGCTCTGCGAGAAGGTGGGTGCGGACGTGGACTTCGTGCGCAAGGGCCTG
GGGTCGGACAAGCGCATCGGCTATCCGTTCCTCTTCCCGGGCGTGGGCTACGGCGGCTCCTGCTTCCCCAAGGACGTGAA
GGCGCTGGTGGCCACCGCGCGTGACTACGGCCTGGAGCTGGACCTGCTGCGCGCGGTGGAGCGCACCAACGAGCGCCAGA
AGAAGCTGCTGGTGACCAAGGCGGCCAAGCACTACGGCTCGCTGGAGGGCCGCAAGTTCGGCGTGTGGGGTCTGGCCTTC
AAGCCGAAGACGGACGACATGCGCGAGGCGCCGTCCATCGAGGTCATCGAGGGCCTCATCGGCAAGGGCGCCCAGGTGAT
TGCGCACGACCCGGTGTCTCCGCACACGGCCAAGCGCGTCTTCGGTGATCGCATCCGCTACGCCTCCGTGCCCTACGAGG
CGCTGGAGGGCGTGGACGGCCTCTTCGTGGTGACGGAGTGGAACGAGTTCCGCCACCCGGACTTCGAGCGCATGAAGACG
CTGATGAAGTCGCCCGTCGTGTTCGACGGCCGCAACGTGTACGACCCGGCGCGCATGCGTGAGCTGGGCTTCACGTACTA
CGGCATCGGCCGGCGGTAG

Upstream 100 bases:

>100_bases
CGGCTGCTCACAGAGGAGCCCCAGTGACGGGGATGGGCTTTCTTTCGGACTCCCTCCCGGCGTATGAGTCCTGCAAGAGA
CATTCACTGGGGCTCCCTCA

Downstream 100 bases:

>100_bases
CGGTGAGCGGGAGCAGGGCCCTCGACGCGCTGACGGGGCTGCGCTTCGTCGCGGCCCTGCACGTCGTGTTGTTCCACTTC
GCGGCGCCGTGTCTGGGCAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRIAIIGTGYVGLVAGTCFADSGNDVTCVDIDERKIRMLQAGEVPIYEPGLEELIKKNVREKRLFFTRDLTEAVTNAQVV
FIAVGTPEGESGDADLQYVLAAAEQIGKAMKQYTVVVDKSTVPVGTADKVREAIRKVTDIEFDVVSNPEFLKEGAALDDF
LKPDRVVIGVDSERARKVMADLYSPFVRTENPVLFMDTRSAELTKYAANAMLATRISFMNDIAALCEKVGADVDFVRKGL
GSDKRIGYPFLFPGVGYGGSCFPKDVKALVATARDYGLELDLLRAVERTNERQKKLLVTKAAKHYGSLEGRKFGVWGLAF
KPKTDDMREAPSIEVIEGLIGKGAQVIAHDPVSPHTAKRVFGDRIRYASVPYEALEGVDGLFVVTEWNEFRHPDFERMKT
LMKSPVVFDGRNVYDPARMRELGFTYYGIGRR

Sequences:

>Translated_432_residues
MRIAIIGTGYVGLVAGTCFADSGNDVTCVDIDERKIRMLQAGEVPIYEPGLEELIKKNVREKRLFFTRDLTEAVTNAQVV
FIAVGTPEGESGDADLQYVLAAAEQIGKAMKQYTVVVDKSTVPVGTADKVREAIRKVTDIEFDVVSNPEFLKEGAALDDF
LKPDRVVIGVDSERARKVMADLYSPFVRTENPVLFMDTRSAELTKYAANAMLATRISFMNDIAALCEKVGADVDFVRKGL
GSDKRIGYPFLFPGVGYGGSCFPKDVKALVATARDYGLELDLLRAVERTNERQKKLLVTKAAKHYGSLEGRKFGVWGLAF
KPKTDDMREAPSIEVIEGLIGKGAQVIAHDPVSPHTAKRVFGDRIRYASVPYEALEGVDGLFVVTEWNEFRHPDFERMKT
LMKSPVVFDGRNVYDPARMRELGFTYYGIGRR
>Mature_432_residues
MRIAIIGTGYVGLVAGTCFADSGNDVTCVDIDERKIRMLQAGEVPIYEPGLEELIKKNVREKRLFFTRDLTEAVTNAQVV
FIAVGTPEGESGDADLQYVLAAAEQIGKAMKQYTVVVDKSTVPVGTADKVREAIRKVTDIEFDVVSNPEFLKEGAALDDF
LKPDRVVIGVDSERARKVMADLYSPFVRTENPVLFMDTRSAELTKYAANAMLATRISFMNDIAALCEKVGADVDFVRKGL
GSDKRIGYPFLFPGVGYGGSCFPKDVKALVATARDYGLELDLLRAVERTNERQKKLLVTKAAKHYGSLEGRKFGVWGLAF
KPKTDDMREAPSIEVIEGLIGKGAQVIAHDPVSPHTAKRVFGDRIRYASVPYEALEGVDGLFVVTEWNEFRHPDFERMKT
LMKSPVVFDGRNVYDPARMRELGFTYYGIGRR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=462, Percent_Identity=36.3636363636364, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI296040438, Length=368, Percent_Identity=36.4130434782609, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI296040443, Length=328, Percent_Identity=35.6707317073171, Blast_Score=186, Evalue=4e-47,
Organism=Escherichia coli, GI1788340, Length=358, Percent_Identity=31.8435754189944, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI48994968, Length=413, Percent_Identity=28.0871670702179, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=465, Percent_Identity=35.4838709677419, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI17136908, Length=462, Percent_Identity=36.1471861471861, Blast_Score=279, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47908; Mature: 47908

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIIGTGYVGLVAGTCFADSGNDVTCVDIDERKIRMLQAGEVPIYEPGLEELIKKNVR
CEEEEEECCHHHHHHHHEECCCCCCEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
EKRLFFTRDLTEAVTNAQVVFIAVGTPEGESGDADLQYVLAAAEQIGKAMKQYTVVVDKS
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGTADKVREAIRKVTDIEFDVVSNPEFLKEGAALDDFLKPDRVVIGVDSERARKVMA
CCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHH
DLYSPFVRTENPVLFMDTRSAELTKYAANAMLATRISFMNDIAALCEKVGADVDFVRKGL
HHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GSDKRIGYPFLFPGVGYGGSCFPKDVKALVATARDYGLELDLLRAVERTNERQKKLLVTK
CCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
AAKHYGSLEGRKFGVWGLAFKPKTDDMREAPSIEVIEGLIGKGAQVIAHDPVSPHTAKRV
HHHHHCCCCCCEEEEEEEEECCCCCHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHH
FGDRIRYASVPYEALEGVDGLFVVTEWNEFRHPDFERMKTLMKSPVVFDGRNVYDPARMR
HHHHHEECCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHHH
ELGFTYYGIGRR
HHCCEEEECCCC
>Mature Secondary Structure
MRIAIIGTGYVGLVAGTCFADSGNDVTCVDIDERKIRMLQAGEVPIYEPGLEELIKKNVR
CEEEEEECCHHHHHHHHEECCCCCCEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
EKRLFFTRDLTEAVTNAQVVFIAVGTPEGESGDADLQYVLAAAEQIGKAMKQYTVVVDKS
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGTADKVREAIRKVTDIEFDVVSNPEFLKEGAALDDFLKPDRVVIGVDSERARKVMA
CCCCCCHHHHHHHHHHHHCCEEEECCCHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHH
DLYSPFVRTENPVLFMDTRSAELTKYAANAMLATRISFMNDIAALCEKVGADVDFVRKGL
HHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GSDKRIGYPFLFPGVGYGGSCFPKDVKALVATARDYGLELDLLRAVERTNERQKKLLVTK
CCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
AAKHYGSLEGRKFGVWGLAFKPKTDDMREAPSIEVIEGLIGKGAQVIAHDPVSPHTAKRV
HHHHHCCCCCCEEEEEEEEECCCCCHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHH
FGDRIRYASVPYEALEGVDGLFVVTEWNEFRHPDFERMKTLMKSPVVFDGRNVYDPARMR
HHHHHEECCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHHH
ELGFTYYGIGRR
HHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]