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The map label for this gene is plsB [H]

Identifier: 108759319

GI number: 108759319

Start: 3840191

End: 3842746

Strand: Reverse

Name: plsB [H]

Synonym: MXAN_3288

Alternate gene names: 108759319

Gene position: 3842746-3840191 (Counterclockwise)

Preceding gene: 108762554

Following gene: 108762197

Centisome position: 42.04

GC content: 68.11

Gene sequence:

>2556_bases
TTGGAGACCGCGCTGTCACCGACTGCGAATCAGGGAGCGTCCTCGCTGAAGGACGAATTCGGCCCCATGGGCCGGGCGCT
GGGAACGCGCTACCTGGAGAGCGTGCACTTCCCGCCGGAAGCAGAAACAGAGCTCCGGAACCTGCACGCCAAGGGCTTCG
TGGTGCACGTCATGCGCACCACCGCCTGGGTGAACTTCCTCTACCTGACGTGGGCCATGGTGCGCCGGGCGCTGCCGCCC
GTGCGCGCCGTGGTGAACCTGCGGCCATGGTTCACCCGACCCTGGCGACAGGCGAAACAGAGCGGTGACTTCACGCAGCG
CTTCGAGCACGCCCGGCAGACGGGGGGCAGCGGTCTGGTCTTCCTGCGCCGCACCGCCCTGCTCCGTCCGTCTGGGAAAG
AGACGCGCGAGGACCCCTTCCCCGCCCTGGTGGCCATGGCCCGCCAGTCCGACAAGCCCGTGTACCTGGTGCCGGAGTTG
TTCGTCTGGGAGAAGCGCCCCGCGCGCCTGAAGCCCAACTGGGTGGACGTGGTGTTCGGCAGCCCCGAGGCACCGGGATT
CCTGCACTCGATGCTGGCCTTCTTCCGCAACTACAAGCGCGCGCAGTTCCGCGTGGGCGAGCCCATCGACCTGCAGCGCT
TCGTCGCGGAGAACCCTCGCGACTCGGACGAACTGCTCGCTCGCAAGGCGCGTAGCAGTCTCCACGTCCACCTCGCGCGC
GAAACGCGGGCCGTGTTCGGTCCGCCGGTGAAGCCCGCCTCGCGCGTCATCGAGGAGACGCTGCGCGACAGGTCCCTGCG
CAAGGTGGTGGAGGAGTGCGCGGCGGAATCCGGGCGCAAGCCGGAGAGCGTCCTGCGCGAGGCTCGCCGCAACCTGGAGG
CCATTGCCGCCAAACCCAGCCCCACCGCGCTGGCGTTCACCTCCCCCGTGCTGGAGTGGGTGTTCAACCGCATCTACGAC
GGCATGCACGTGGACGAGGCCGGCCTCCACCGCGCGCTCAAGGCCGCGAGCCACGCGCCCATCGTCCTGTGCCCCAGCCA
CAAGAGCCACGTCGACTACCTGGTAATGAGCTGGGTGCTATGGAACCGGGGCTACGCGGTGCCCCTGGTGGCCGCGGGCG
CCAACCTCTCCTTCTGGCCCCTGGGCACGTTCTTCCGCCGCTGTGGCGCGTTCTTCCTCCGGCGCTCCTTCAAGGGCGAC
AAGGTCTACGCCGCGTCCTTCAAGGCCTACGTGCGCAAGCTGGTGCACGACGGCATCCACCAGGAGTTCTTCCCGGAAGG
CGGCCGTTCGCGCACGGGCAAGCTGTTGTTGCCCAAGCTGGGCATGTTCACCTGGCAGGTGGAGTCCGTGCTGGAGGGCG
CGCGCGATGACCTCATCTTCGTGCCGGTGGCCATCGACTACGAGAAGGTCGTCGAGTCCAGCAGCTACTCGAAGGAGCTG
GCTGGCGGAGAGAAGAAGCCCGAGGACCTCAAGGCGCTCTTGAGCACGCCCAAGGTGCTGGCGGCGCGGTACGGCCGCAT
CCACCTGGGCTTCGATGAGCCCATCTCCCTGCGCGCGTTCATGCAGGCACGTGGCATCAACCCGGACGAACCGGTGTCGG
ACGAACAGAAGAAGGGGCTCGTCCGCGCGCTGGGCAACCGGGTGATGTACGGCATCAGCAAGGTGTCCACGGTGACGCCG
CACGCGCTGGTCAGCACCGCCCTGCTCTCGCACCGGCGCCGCGGCTTGACGCAGCGGGAGATGGCAGACCGCATCAACAT
CCTGCGCCGCATCGCCGTGGAGGAGGGCTCGCCTCAGTCGGTGGAGATGCGCAACGCCCCCAGCAACCCGGAGACGATGG
GCCCCATCCAGGACGCCATGCGCACGTTCATCTCCGACGAGATGGTGCGCACCCAGGAAGCGCGTGGCGAGGTCATCTAC
CAGGTCGAGGAGGCACGCCGCCCGGAGCTGTCCTTCTACAAGAACACGCTGATGAACCTGGTGGCCTCCCGGAGCCTCGT
GGCCAACGCCATGCTTGCCAGCGGCAGCCCGGCGCCCTACGACACCGTGAAGGAGCGCGCGCTGTTCCTGTCCCGCCTCT
TCAAGGTGGAATTCATCTACCGGGTGGGCACCACGTTCGACTCTATCTTCGCGGAGACGGTGGAGCGGCTGGAGCGCATG
GGCCTGGTGCTTGAGGAGAACGAGACGCTCCGCGTGGCCCCCGAGGCCCACGCGCGTCCGGACCTGGAGTTCCTGGCCGA
CATGCTGCGCGACTACCTGGAGGCCTACCTGCTGGCGGCCCTGACGCTCCAGGATGTGGCCACCGGCGCCGCGGAGGACC
GGAAGTCCTTCGTGAAGATGGCCCTGGAAACGGGCCGCGCGGAGTACCACGCCGGCCGCATCACCGCCTCCGAGTCCCTG
GCCAAGGTGACGCTGGAGAACGCGGTGGCGTTCCTCCTGGACCAGAAGCTGCTCATCGAGGCCGACAAGAAGCTGACGCT
GGGCCCCGCCGCCACCGAGCAGCAGGCCCGCACACAGCTCGTGGACGACATCCGTGGGTACCTGAAGCGCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCGACTCGCCCTCATCGACGCCGCCCGGGTTACTCTGGCCGCGGGACTGACGCTGCTGGGCATTCCCACGCCCGACA
ACATGTAGCCGGGAGCATTC

Downstream 100 bases:

>100_bases
GCAGCCCTCCCTGGCCCCGTCCGCGCCCGCCACCGCGCTGTTCGAGCCAGGATGAAGGGCGTCAAGGTTCGAGCACGAGA
GGAATAGGAGAAAGCCCGTT

Product: acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
METALSPTANQGASSLKDEFGPMGRALGTRYLESVHFPPEAETELRNLHAKGFVVHVMRTTAWVNFLYLTWAMVRRALPP
VRAVVNLRPWFTRPWRQAKQSGDFTQRFEHARQTGGSGLVFLRRTALLRPSGKETREDPFPALVAMARQSDKPVYLVPEL
FVWEKRPARLKPNWVDVVFGSPEAPGFLHSMLAFFRNYKRAQFRVGEPIDLQRFVAENPRDSDELLARKARSSLHVHLAR
ETRAVFGPPVKPASRVIEETLRDRSLRKVVEECAAESGRKPESVLREARRNLEAIAAKPSPTALAFTSPVLEWVFNRIYD
GMHVDEAGLHRALKAASHAPIVLCPSHKSHVDYLVMSWVLWNRGYAVPLVAAGANLSFWPLGTFFRRCGAFFLRRSFKGD
KVYAASFKAYVRKLVHDGIHQEFFPEGGRSRTGKLLLPKLGMFTWQVESVLEGARDDLIFVPVAIDYEKVVESSSYSKEL
AGGEKKPEDLKALLSTPKVLAARYGRIHLGFDEPISLRAFMQARGINPDEPVSDEQKKGLVRALGNRVMYGISKVSTVTP
HALVSTALLSHRRRGLTQREMADRINILRRIAVEEGSPQSVEMRNAPSNPETMGPIQDAMRTFISDEMVRTQEARGEVIY
QVEEARRPELSFYKNTLMNLVASRSLVANAMLASGSPAPYDTVKERALFLSRLFKVEFIYRVGTTFDSIFAETVERLERM
GLVLEENETLRVAPEAHARPDLEFLADMLRDYLEAYLLAALTLQDVATGAAEDRKSFVKMALETGRAEYHAGRITASESL
AKVTLENAVAFLLDQKLLIEADKKLTLGPAATEQQARTQLVDDIRGYLKRG

Sequences:

>Translated_851_residues
METALSPTANQGASSLKDEFGPMGRALGTRYLESVHFPPEAETELRNLHAKGFVVHVMRTTAWVNFLYLTWAMVRRALPP
VRAVVNLRPWFTRPWRQAKQSGDFTQRFEHARQTGGSGLVFLRRTALLRPSGKETREDPFPALVAMARQSDKPVYLVPEL
FVWEKRPARLKPNWVDVVFGSPEAPGFLHSMLAFFRNYKRAQFRVGEPIDLQRFVAENPRDSDELLARKARSSLHVHLAR
ETRAVFGPPVKPASRVIEETLRDRSLRKVVEECAAESGRKPESVLREARRNLEAIAAKPSPTALAFTSPVLEWVFNRIYD
GMHVDEAGLHRALKAASHAPIVLCPSHKSHVDYLVMSWVLWNRGYAVPLVAAGANLSFWPLGTFFRRCGAFFLRRSFKGD
KVYAASFKAYVRKLVHDGIHQEFFPEGGRSRTGKLLLPKLGMFTWQVESVLEGARDDLIFVPVAIDYEKVVESSSYSKEL
AGGEKKPEDLKALLSTPKVLAARYGRIHLGFDEPISLRAFMQARGINPDEPVSDEQKKGLVRALGNRVMYGISKVSTVTP
HALVSTALLSHRRRGLTQREMADRINILRRIAVEEGSPQSVEMRNAPSNPETMGPIQDAMRTFISDEMVRTQEARGEVIY
QVEEARRPELSFYKNTLMNLVASRSLVANAMLASGSPAPYDTVKERALFLSRLFKVEFIYRVGTTFDSIFAETVERLERM
GLVLEENETLRVAPEAHARPDLEFLADMLRDYLEAYLLAALTLQDVATGAAEDRKSFVKMALETGRAEYHAGRITASESL
AKVTLENAVAFLLDQKLLIEADKKLTLGPAATEQQARTQLVDDIRGYLKRG
>Mature_851_residues
METALSPTANQGASSLKDEFGPMGRALGTRYLESVHFPPEAETELRNLHAKGFVVHVMRTTAWVNFLYLTWAMVRRALPP
VRAVVNLRPWFTRPWRQAKQSGDFTQRFEHARQTGGSGLVFLRRTALLRPSGKETREDPFPALVAMARQSDKPVYLVPEL
FVWEKRPARLKPNWVDVVFGSPEAPGFLHSMLAFFRNYKRAQFRVGEPIDLQRFVAENPRDSDELLARKARSSLHVHLAR
ETRAVFGPPVKPASRVIEETLRDRSLRKVVEECAAESGRKPESVLREARRNLEAIAAKPSPTALAFTSPVLEWVFNRIYD
GMHVDEAGLHRALKAASHAPIVLCPSHKSHVDYLVMSWVLWNRGYAVPLVAAGANLSFWPLGTFFRRCGAFFLRRSFKGD
KVYAASFKAYVRKLVHDGIHQEFFPEGGRSRTGKLLLPKLGMFTWQVESVLEGARDDLIFVPVAIDYEKVVESSSYSKEL
AGGEKKPEDLKALLSTPKVLAARYGRIHLGFDEPISLRAFMQARGINPDEPVSDEQKKGLVRALGNRVMYGISKVSTVTP
HALVSTALLSHRRRGLTQREMADRINILRRIAVEEGSPQSVEMRNAPSNPETMGPIQDAMRTFISDEMVRTQEARGEVIY
QVEEARRPELSFYKNTLMNLVASRSLVANAMLASGSPAPYDTVKERALFLSRLFKVEFIYRVGTTFDSIFAETVERLERM
GLVLEENETLRVAPEAHARPDLEFLADMLRDYLEAYLLAALTLQDVATGAAEDRKSFVKMALETGRAEYHAGRITASESL
AKVTLENAVAFLLDQKLLIEADKKLTLGPAATEQQARTQLVDDIRGYLKRG

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=563, Percent_Identity=27.708703374778, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI190358539, Length=557, Percent_Identity=22.0825852782765, Blast_Score=131, Evalue=3e-30,
Organism=Escherichia coli, GI87082362, Length=622, Percent_Identity=28.6173633440514, Blast_Score=244, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI25147672, Length=332, Percent_Identity=29.2168674698795, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71988723, Length=592, Percent_Identity=25, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71988728, Length=545, Percent_Identity=24.7706422018349, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17864692, Length=396, Percent_Identity=29.5454545454545, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21357731, Length=324, Percent_Identity=28.7037037037037, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24650752, Length=324, Percent_Identity=28.7037037037037, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24650754, Length=324, Percent_Identity=28.7037037037037, Blast_Score=145, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 95725; Mature: 95725

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METALSPTANQGASSLKDEFGPMGRALGTRYLESVHFPPEAETELRNLHAKGFVVHVMRT
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHH
TAWVNFLYLTWAMVRRALPPVRAVVNLRPWFTRPWRQAKQSGDFTQRFEHARQTGGSGLV
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEE
FLRRTALLRPSGKETREDPFPALVAMARQSDKPVYLVPELFVWEKRPARLKPNWVDVVFG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCHHHHCCCCCCCCCCCEEEEEEC
SPEAPGFLHSMLAFFRNYKRAQFRVGEPIDLQRFVAENPRDSDELLARKARSSLHVHLAR
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHEEEEHH
ETRAVFGPPVKPASRVIEETLRDRSLRKVVEECAAESGRKPESVLREARRNLEAIAAKPS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHEECCCC
PTALAFTSPVLEWVFNRIYDGMHVDEAGLHRALKAASHAPIVLCPSHKSHVDYLVMSWVL
CCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
WNRGYAVPLVAAGANLSFWPLGTFFRRCGAFFLRRSFKGDKVYAASFKAYVRKLVHDGIH
HCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
QEFFPEGGRSRTGKLLLPKLGMFTWQVESVLEGARDDLIFVPVAIDYEKVVESSSYSKEL
HHHCCCCCCCCCCCEECCHHCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCHHHHH
AGGEKKPEDLKALLSTPKVLAARYGRIHLGFDEPISLRAFMQARGINPDEPVSDEQKKGL
CCCCCCHHHHHHHHHCHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
VRALGNRVMYGISKVSTVTPHALVSTALLSHRRRGLTQREMADRINILRRIAVEEGSPQS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
VEMRNAPSNPETMGPIQDAMRTFISDEMVRTQEARGEVIYQVEEARRPELSFYKNTLMNL
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHHHHHHHHH
VASRSLVANAMLASGSPAPYDTVKERALFLSRLFKVEFIYRVGTTFDSIFAETVERLERM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
GLVLEENETLRVAPEAHARPDLEFLADMLRDYLEAYLLAALTLQDVATGAAEDRKSFVKM
CCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALETGRAEYHAGRITASESLAKVTLENAVAFLLDQKLLIEADKKLTLGPAATEQQARTQL
HHHHCCHHHHCCCEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHH
VDDIRGYLKRG
HHHHHHHHCCC
>Mature Secondary Structure
METALSPTANQGASSLKDEFGPMGRALGTRYLESVHFPPEAETELRNLHAKGFVVHVMRT
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHH
TAWVNFLYLTWAMVRRALPPVRAVVNLRPWFTRPWRQAKQSGDFTQRFEHARQTGGSGLV
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEE
FLRRTALLRPSGKETREDPFPALVAMARQSDKPVYLVPELFVWEKRPARLKPNWVDVVFG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCHHHHCCCCCCCCCCCEEEEEEC
SPEAPGFLHSMLAFFRNYKRAQFRVGEPIDLQRFVAENPRDSDELLARKARSSLHVHLAR
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHEEEEHH
ETRAVFGPPVKPASRVIEETLRDRSLRKVVEECAAESGRKPESVLREARRNLEAIAAKPS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHEECCCC
PTALAFTSPVLEWVFNRIYDGMHVDEAGLHRALKAASHAPIVLCPSHKSHVDYLVMSWVL
CCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
WNRGYAVPLVAAGANLSFWPLGTFFRRCGAFFLRRSFKGDKVYAASFKAYVRKLVHDGIH
HCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
QEFFPEGGRSRTGKLLLPKLGMFTWQVESVLEGARDDLIFVPVAIDYEKVVESSSYSKEL
HHHCCCCCCCCCCCEECCHHCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCHHHHH
AGGEKKPEDLKALLSTPKVLAARYGRIHLGFDEPISLRAFMQARGINPDEPVSDEQKKGL
CCCCCCHHHHHHHHHCHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
VRALGNRVMYGISKVSTVTPHALVSTALLSHRRRGLTQREMADRINILRRIAVEEGSPQS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
VEMRNAPSNPETMGPIQDAMRTFISDEMVRTQEARGEVIYQVEEARRPELSFYKNTLMNL
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHHHHHHHHH
VASRSLVANAMLASGSPAPYDTVKERALFLSRLFKVEFIYRVGTTFDSIFAETVERLERM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
GLVLEENETLRVAPEAHARPDLEFLADMLRDYLEAYLLAALTLQDVATGAAEDRKSFVKM
CCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALETGRAEYHAGRITASESLAKVTLENAVAFLLDQKLLIEADKKLTLGPAATEQQARTQL
HHHHCCHHHHCCCEEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHH
VDDIRGYLKRG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA