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The map label for this gene is pccB [H]

Identifier: 108759197

GI number: 108759197

Start: 1295455

End: 1297017

Strand: Reverse

Name: pccB [H]

Synonym: MXAN_1113

Alternate gene names: 108759197

Gene position: 1297017-1295455 (Counterclockwise)

Preceding gene: 108762091

Following gene: 108757674

Centisome position: 14.19

GC content: 66.41

Gene sequence:

>1563_bases
ATGGACCAGACTCCCGAGAAGGACCCCCTCCGCGCACGTCTCGAGAAGATGGAGAAGCAAGCCGAGCTGGGTGGCGGTGC
CGACCGCATCGCCAAGCAGCACGAGTCCGGCAAGCTCACCGCCCGCGAGCGCATCGACCTGCTCCTTGACCCCGGCTCCT
TCTGTGAGCTGGACAAGTTCGTCACCCACCGCTCGAGCGAGTTCGGCATGGGCGACAAGAAGATTCCAGGCGACGGCGTC
GTCACCGGCTACGGCACCGTGGAAGGCCGCAAGGTCTTCGTCTTCGCCCAGGACTTCACCGTCTTCGGCGGCTCGCTGTC
GGGCGCCTACGCGCAGAAGATCTGCAAGATCATGGACCTGGCCACCCGCGTGGGTGCGCCCGTCATCGGCCTGAATGACT
CGGGCGGCGCGCGCATCCAGGAAGGCGTGGAGAGCCTGGCCGGCTACGCGGACATCTTCGTGCGCAACACGCTGGCCTCC
GGCGTGGTGCCCCAGATTTCGCTCATCATGGGCCCGTGCGCGGGCGGCGCGGTGTACTCGCCGGCCATCACCGACTTCAT
CATGATGGTGAAGGACACGTCGTACATGTTCATCACCGGCCCGGACGTCATCAAGACGGTGACGCACGAGGAGGTGTCGA
AGGAAGCGCTGGGCGGCGCCGTCACGCACAACCAGAAGTCCGGCGTGGCCCACTTCGCGGCGGAGAACGAGCAGGCCGCC
ATCGTGATGACGCGCGAGCTGCTCTCCTTCCTGCCCTCCAACAACCAGGAAGAGGCGCCCGTCCAGCCGTGCGAGGACGA
CGCGTTCCGGGCCGAGGAGTCGCTCAAGACGATTGTCCCGAGCAACCCCAACAAGCCCTACGACATCAAGGAAGTCATCA
AGGCCATCGTCGACGACAAGCACTTCTTCGAGGTGCAGGAGCACTTCGCGAAGAACATCGTCATCGGCTTCGCGCGCATG
AACGGGCGCAGCGTGGGCGTCGTCGCCAACCAGCCCGCGGTGCTCGCCGGCGTGCTGGACATCGACGCCAGCATCAAGGC
CGCGCGCTTCGTGCGCTTCTGCGACTGCTTCAACATCCCGCTCGTCACGCTGGTGGACGTGCCCGGCTTCCTCCCCGGCA
CCGACCAGGAGTGGGGCGGCATCATCACCCACGGCGCCAAGCTGCTGTACGCCTACGCCGAGGCCACCGTCCCCAAGGTC
ACCGTCATCACCCGCAAGGCCTACGGCGGCGCCTATGACGTCATGGCGTCCAAGCACATCCGCGCGGACATGAACTTCGC
CTGGCCCACCGCGGAAATCGCCGTCATGGGCCCCGAGGGCGCGGTCAACATCATCTTCCGCAACGAGCTGGCCAAGGCCC
CGGACGCCGCCGCTGAGCGGGCCCGGCTGACGGCGGACTACCGCGACAAGTTCGCCACCCCGTTCAAGGCGGCCGAGCTG
GGCTACATCGACGAAATCATCCGTCCGGAGGAGACGCGCGCGAAGCTCATCCGCTCCCTGGAGCTGCTGAAGGACAAGCG
CCAGGAGAACCTCCCCCGCAAGCACGGCAACATCCCGCTCTAG

Upstream 100 bases:

>100_bases
GGCGGCGGTGGATGCAGTGCTTGACGACCCCATGCGTCCGGCCATGGAAGTCAGGAATCCAGGCAGCGCGTCCCCGCCCC
AATCATGCTAGACGCGCCCC

Downstream 100 bases:

>100_bases
GTTTCTTTCAGCCCTCGCCTGCCCGCCCTCTGTCGCCAGCAGGGCAGGCAGGCGCGCGCGAAGGGGGAAATTTGGGGGTG
ACGAACGGGCTTACAGGGGC

Product: propionyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MDQTPEKDPLRARLEKMEKQAELGGGADRIAKQHESGKLTARERIDLLLDPGSFCELDKFVTHRSSEFGMGDKKIPGDGV
VTGYGTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDLATRVGAPVIGLNDSGGARIQEGVESLAGYADIFVRNTLAS
GVVPQISLIMGPCAGGAVYSPAITDFIMMVKDTSYMFITGPDVIKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAA
IVMTRELLSFLPSNNQEEAPVQPCEDDAFRAEESLKTIVPSNPNKPYDIKEVIKAIVDDKHFFEVQEHFAKNIVIGFARM
NGRSVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIPLVTLVDVPGFLPGTDQEWGGIITHGAKLLYAYAEATVPKV
TVITRKAYGGAYDVMASKHIRADMNFAWPTAEIAVMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAEL
GYIDEIIRPEETRAKLIRSLELLKDKRQENLPRKHGNIPL

Sequences:

>Translated_520_residues
MDQTPEKDPLRARLEKMEKQAELGGGADRIAKQHESGKLTARERIDLLLDPGSFCELDKFVTHRSSEFGMGDKKIPGDGV
VTGYGTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDLATRVGAPVIGLNDSGGARIQEGVESLAGYADIFVRNTLAS
GVVPQISLIMGPCAGGAVYSPAITDFIMMVKDTSYMFITGPDVIKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAA
IVMTRELLSFLPSNNQEEAPVQPCEDDAFRAEESLKTIVPSNPNKPYDIKEVIKAIVDDKHFFEVQEHFAKNIVIGFARM
NGRSVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIPLVTLVDVPGFLPGTDQEWGGIITHGAKLLYAYAEATVPKV
TVITRKAYGGAYDVMASKHIRADMNFAWPTAEIAVMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAEL
GYIDEIIRPEETRAKLIRSLELLKDKRQENLPRKHGNIPL
>Mature_520_residues
MDQTPEKDPLRARLEKMEKQAELGGGADRIAKQHESGKLTARERIDLLLDPGSFCELDKFVTHRSSEFGMGDKKIPGDGV
VTGYGTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDLATRVGAPVIGLNDSGGARIQEGVESLAGYADIFVRNTLAS
GVVPQISLIMGPCAGGAVYSPAITDFIMMVKDTSYMFITGPDVIKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAA
IVMTRELLSFLPSNNQEEAPVQPCEDDAFRAEESLKTIVPSNPNKPYDIKEVIKAIVDDKHFFEVQEHFAKNIVIGFARM
NGRSVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIPLVTLVDVPGFLPGTDQEWGGIITHGAKLLYAYAEATVPKV
TVITRKAYGGAYDVMASKHIRADMNFAWPTAEIAVMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAEL
GYIDEIIRPEETRAKLIRSLELLKDKRQENLPRKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=510, Percent_Identity=64.5098039215686, Blast_Score=669, Evalue=0.0,
Organism=Homo sapiens, GI295821216, Length=530, Percent_Identity=62.0754716981132, Blast_Score=656, Evalue=0.0,
Organism=Homo sapiens, GI11545863, Length=504, Percent_Identity=34.1269841269841, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI38679974, Length=343, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI38679960, Length=343, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI38679977, Length=343, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI38679967, Length=343, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI38679971, Length=343, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI134142062, Length=341, Percent_Identity=25.2199413489736, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788655, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=508, Percent_Identity=61.8110236220472, Blast_Score=648, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147359, Length=508, Percent_Identity=61.8110236220472, Blast_Score=647, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552936, Length=501, Percent_Identity=34.5309381237525, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71997163, Length=346, Percent_Identity=26.3005780346821, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133931226, Length=335, Percent_Identity=22.089552238806, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324343, Length=365, Percent_Identity=22.7397260273973, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24586065, Length=526, Percent_Identity=34.4106463878327, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 56561; Mature: 56561

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQTPEKDPLRARLEKMEKQAELGGGADRIAKQHESGKLTARERIDLLLDPGSFCELDKF
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCEEEEECCCCHHHHHHH
VTHRSSEFGMGDKKIPGDGVVTGYGTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDL
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECEEEECCCCCHHHHHHHHHHHHH
ATRVGAPVIGLNDSGGARIQEGVESLAGYADIFVRNTLASGVVPQISLIMGPCAGGAVYS
HHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEECCCCCCCCCC
PAITDFIMMVKDTSYMFITGPDVIKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAA
HHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEE
IVMTRELLSFLPSNNQEEAPVQPCEDDAFRAEESLKTIVPSNPNKPYDIKEVIKAIVDDK
EEEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCH
HFFEVQEHFAKNIVIGFARMNGRSVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIP
HHHHHHHHHHHHEEEEEEEECCCEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCC
LVTLVDVPGFLPGTDQEWGGIITHGAKLLYAYAEATVPKVTVITRKAYGGAYDVMASKHI
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
RADMNFAWPTAEIAVMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAEL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
GYIDEIIRPEETRAKLIRSLELLKDKRQENLPRKHGNIPL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDQTPEKDPLRARLEKMEKQAELGGGADRIAKQHESGKLTARERIDLLLDPGSFCELDKF
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCEEEEECCCCHHHHHHH
VTHRSSEFGMGDKKIPGDGVVTGYGTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDL
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECEEEECCCCCHHHHHHHHHHHHH
ATRVGAPVIGLNDSGGARIQEGVESLAGYADIFVRNTLASGVVPQISLIMGPCAGGAVYS
HHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEECCCCCCCCCC
PAITDFIMMVKDTSYMFITGPDVIKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAA
HHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEE
IVMTRELLSFLPSNNQEEAPVQPCEDDAFRAEESLKTIVPSNPNKPYDIKEVIKAIVDDK
EEEHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCH
HFFEVQEHFAKNIVIGFARMNGRSVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIP
HHHHHHHHHHHHEEEEEEEECCCEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCC
LVTLVDVPGFLPGTDQEWGGIITHGAKLLYAYAEATVPKVTVITRKAYGGAYDVMASKHI
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHH
RADMNFAWPTAEIAVMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAEL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
GYIDEIIRPEETRAKLIRSLELLKDKRQENLPRKHGNIPL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]