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The map label for this gene is macB [H]

Identifier: 108758934

GI number: 108758934

Start: 5157240

End: 5158445

Strand: Direct

Name: macB [H]

Synonym: MXAN_4201

Alternate gene names: 108758934

Gene position: 5157240-5158445 (Clockwise)

Preceding gene: 108759744

Following gene: 108763850

Centisome position: 56.43

GC content: 68.49

Gene sequence:

>1206_bases
ATGGGTGAAATCATCCGGGTCGCATTCGATGCGGTCCTCGCCAACAAGCTGCGGTCGCTGCTGACCATGTTGGGCATCGT
CATCGGCATCGCGGCCGTCATCACCATGGTCGCGCTGGGCGAAGGGGCGCAGCGCTCGGTGGCCCAGCGGCTCCAGGGAC
TGGGCACCAACGTCCTCACGGTACGCCCGGGTCAGGCGTTCACGGGCGGCATGATTCGCGCCCAGGCGTCGATGACCATC
GACGACGCGGAGGCGCTGCGGGAGAACGCGCGCCACATCCAGGCCGTGGCGCCGGAAATCGAGTCGCGCTTCCAGGTGGA
GTACGGCGCGAAGAACGCGAACCTGTCCGTCGTGGGCACCTGGCCGGACTACTTCCACGTCAACCAGGGGCAGATCACGA
ACGGCCGGCTCTTCACGGACGCGGAGGACAAGGGCCGCCGCCGGGTGGTGGTGCTGGGCGCCCTGGCCGGTGCGCAGCTG
GGCCTGACGGACACCGCATCCCTGGTGGGCGAGTCCATCCGCATCCGGGGCATTCCGTTCGAGGTCATCGGGGTGCTGGC
CGAAAAGGGCGCGCAGGGCTTCAACAACCCGGATGAGAGCCTCTACATCCCGCTGTCCACCGCGCAGTTCCGCGTCATGG
GCAGCGACCGCATCCGCTCCATCGCGGTGCAGGCCGTGAGCGACACGGCCATGGACGACGCGATGGCGGAGATCGACCAG
AAGCTCCGGCGTGAGCACCGGCTGCGCCCGGAGCAGCCCGCGGACTTCAACATCCGCGACCAGGCCTCGCTGCTCAACAC
CATGCAGGAGACGACGCAGACGTTCTCCCTGCTGCTGGCCGGCATCGCCGCCATCTCCCTGCTGGTGGGAGGCATTGGCA
TCATGAACATCATGCTGGTGTCGGTGACGGAGCGCACGCGCGAGATTGGTCTGCGCAAGGCGCTGGGCGCCACCGGCACG
GACATCATGCTCCAGTTCCTCGTGGAGTCCCTGGTGCTGTGCCTCGCCGGAGGAACGCTGGGCCTGCTGCTGGGCATGGG
CGGCGCGGCGATGCTCCAACGCATGGCGGGCTGGACGGTGGTGGTGGCACCCGAGGCCATCATCGTGGCCATCGCCTTCT
CGGCGACCGTGGGCGTGTTCTTCGGCATCTGGCCGGCGCGGCGCGCGGCGAGCCTCGCGCCCATCGAGTCGCTCCGTTAC
GAGTAG

Upstream 100 bases:

>100_bases
ACACCGAGCGGATGCGCCAGATGTCAGGCGGCGTGATTCCCGGCGCGGGTGGTGGCCCGCGCGGGCCGCGCTAACCCCAG
CCCCATCAGGAGGACACGTC

Downstream 100 bases:

>100_bases
CCGGTGTCCGTCTGCGGGCCTGACTCGAGGAGGGACGACATGGCGGATGACAAGCGAATCGCGTGCATCGTGGGGAGCGG
GAAGCCCGCACCTGACATGG

Product: putative macrolide efflux ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MGEIIRVAFDAVLANKLRSLLTMLGIVIGIAAVITMVALGEGAQRSVAQRLQGLGTNVLTVRPGQAFTGGMIRAQASMTI
DDAEALRENARHIQAVAPEIESRFQVEYGAKNANLSVVGTWPDYFHVNQGQITNGRLFTDAEDKGRRRVVVLGALAGAQL
GLTDTASLVGESIRIRGIPFEVIGVLAEKGAQGFNNPDESLYIPLSTAQFRVMGSDRIRSIAVQAVSDTAMDDAMAEIDQ
KLRREHRLRPEQPADFNIRDQASLLNTMQETTQTFSLLLAGIAAISLLVGGIGIMNIMLVSVTERTREIGLRKALGATGT
DIMLQFLVESLVLCLAGGTLGLLLGMGGAAMLQRMAGWTVVVAPEAIIVAIAFSATVGVFFGIWPARRAASLAPIESLRY
E

Sequences:

>Translated_401_residues
MGEIIRVAFDAVLANKLRSLLTMLGIVIGIAAVITMVALGEGAQRSVAQRLQGLGTNVLTVRPGQAFTGGMIRAQASMTI
DDAEALRENARHIQAVAPEIESRFQVEYGAKNANLSVVGTWPDYFHVNQGQITNGRLFTDAEDKGRRRVVVLGALAGAQL
GLTDTASLVGESIRIRGIPFEVIGVLAEKGAQGFNNPDESLYIPLSTAQFRVMGSDRIRSIAVQAVSDTAMDDAMAEIDQ
KLRREHRLRPEQPADFNIRDQASLLNTMQETTQTFSLLLAGIAAISLLVGGIGIMNIMLVSVTERTREIGLRKALGATGT
DIMLQFLVESLVLCLAGGTLGLLLGMGGAAMLQRMAGWTVVVAPEAIIVAIAFSATVGVFFGIWPARRAASLAPIESLRY
E
>Mature_400_residues
GEIIRVAFDAVLANKLRSLLTMLGIVIGIAAVITMVALGEGAQRSVAQRLQGLGTNVLTVRPGQAFTGGMIRAQASMTID
DAEALRENARHIQAVAPEIESRFQVEYGAKNANLSVVGTWPDYFHVNQGQITNGRLFTDAEDKGRRRVVVLGALAGAQLG
LTDTASLVGESIRIRGIPFEVIGVLAEKGAQGFNNPDESLYIPLSTAQFRVMGSDRIRSIAVQAVSDTAMDDAMAEIDQK
LRREHRLRPEQPADFNIRDQASLLNTMQETTQTFSLLLAGIAAISLLVGGIGIMNIMLVSVTERTREIGLRKALGATGTD
IMLQFLVESLVLCLAGGTLGLLLGMGGAAMLQRMAGWTVVVAPEAIIVAIAFSATVGVFFGIWPARRAASLAPIESLRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=402, Percent_Identity=38.3084577114428, Blast_Score=235, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42856; Mature: 42725

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIIRVAFDAVLANKLRSLLTMLGIVIGIAAVITMVALGEGAQRSVAQRLQGLGTNVLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
VRPGQAFTGGMIRAQASMTIDDAEALRENARHIQAVAPEIESRFQVEYGAKNANLSVVGT
ECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEC
WPDYFHVNQGQITNGRLFTDAEDKGRRRVVVLGALAGAQLGLTDTASLVGESIRIRGIPF
CCCCEECCCCCEECCEEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHCCCCEEEECCCH
EVIGVLAEKGAQGFNNPDESLYIPLSTAQFRVMGSDRIRSIAVQAVSDTAMDDAMAEIDQ
HHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRREHRLRPEQPADFNIRDQASLLNTMQETTQTFSLLLAGIAAISLLVGGIGIMNIMLV
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTERTREIGLRKALGATGTDIMLQFLVESLVLCLAGGTLGLLLGMGGAAMLQRMAGWTV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCCEE
VVAPEAIIVAIAFSATVGVFFGIWPARRAASLAPIESLRYE
EECCCCEEHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCC
>Mature Secondary Structure 
GEIIRVAFDAVLANKLRSLLTMLGIVIGIAAVITMVALGEGAQRSVAQRLQGLGTNVLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
VRPGQAFTGGMIRAQASMTIDDAEALRENARHIQAVAPEIESRFQVEYGAKNANLSVVGT
ECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEC
WPDYFHVNQGQITNGRLFTDAEDKGRRRVVVLGALAGAQLGLTDTASLVGESIRIRGIPF
CCCCEECCCCCEECCEEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHCCCCEEEECCCH
EVIGVLAEKGAQGFNNPDESLYIPLSTAQFRVMGSDRIRSIAVQAVSDTAMDDAMAEIDQ
HHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRREHRLRPEQPADFNIRDQASLLNTMQETTQTFSLLLAGIAAISLLVGGIGIMNIMLV
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTERTREIGLRKALGATGTDIMLQFLVESLVLCLAGGTLGLLLGMGGAAMLQRMAGWTV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCCEE
VVAPEAIIVAIAFSATVGVFFGIWPARRAASLAPIESLRYE
EECCCCEEHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA