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The map label for this gene is 108758932

Identifier: 108758932

GI number: 108758932

Start: 2934478

End: 2935827

Strand: Direct

Name: 108758932

Synonym: MXAN_2521

Alternate gene names: NA

Gene position: 2934478-2935827 (Clockwise)

Preceding gene: 108759941

Following gene: 108760355

Centisome position: 32.11

GC content: 71.93

Gene sequence:

>1350_bases
TTGCCGGGGAGAAAAGGGATGAACGAGTCGTCGCTGCGTGAGCTCGGGATGGACCTCATCGAGGAGCGCCAGTTCGAGCG
AGCCCTGGCCGTGTTCGCCGAGGCGGTTCGCCGCGTCCCCGCGGACCACCGCTCGCGGATGCTGGCCGCGCGCTGCCTGG
CGGAACTGGGCGAGCGTGAGCGCGCCGTCACCGCCTACCACGCCTGCGCGGAGGGCTTGCTGCGCCGGGACTACCTGTTG
TCCGCCATGGCCGCGTGCAAGCTGGCGCTGGACCTGGCGCCCAACGAGCGGCGCTTGAAGGAGACGCTGTTTCGAGTGCA
CTCGCGCGCGGTGCGCAACGCGCCGGGCCGCGCGGTGGTGCCTCCGCCGCTGCCGCCCGAAACCCTCTACGACGGCAAGG
TGGAGACGGACCTGATGGGGCTGCAGGGCGAGGAATTGTCCAGCCGCGCCATCGAAGTGCTGGCCGCGACGGACCCGGGC
GGCGCCGCGGACCCCAACAGCCGTCCGCCGTTGCCGCTGTTCGCGGAGCTGGACCGGGATGCCTTCGTGGACCTGGTGCG
GCTGATGGCGTGGCGCCGCGTGAAGCCGGAGGAGGCGGTGAGCCGCGAGGGCGAGCCCGCCGACTCCCTCTACGTCCTGG
TCGCCGGCAAGGCGGAGGTGACGCGACAGATGGAGGGCGAGGCGCGCACGCTGGGCTTCCTCGGCGGTGGCTCCATCTTC
GGTGAAATCGCGCTGCTGACGGGCGCTCCGCCCACGGCGACGGTGTCCGCGGTGTCGGACACGGAAGTCTTCGAGATTCG
CCGCGAGCACCTCAACGCGGTCGCCAAGAGCCACCCCGCGGTGCCGCAGGTGCTGGCGGACTTCGCGCAGCAGCGCATGG
CGCGCAACCTGATGGCCACCTCGCCCATGTTCCAGACGATGCCGGAGTCGGAGCGGGGCGCGCTGCTGCGGCGCTTCACC
TTCCGGGCGCTCCAGGCTCGGGAGAAGGTGCTGGTGGAGGGCGAGCACTCGCCGGGGCTGTTCCTGGTGCTGGCCGGTGA
GCTGGTGGTGCAGAAGGAGGACCCGGCGGGCGGCGTGGTGACGCTGGGCATGCTGCGCGAGGGCGAGGTCGCGGGCGAAA
TCTCCCTGCTGACGGGCCTGCGCGCGACGGCCACGGTGGCGGCGGCGCGCAAGACGGCTGCGGCCTTCCTGGAGCGCGCG
GCCTTCCACGAACTGGTGACGGCCGTTCCGGACATCCGCACGTACCTGGAGCAGCTGTCGGACCGCCGGCTGAAGCAGAT
TGGCGAGGCGCTGCGGCCCGCGGAAATCATCGACGCGGACGAACTGGTGCTCGAGCCCGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
GTCGTCATCGAGACGGCCTCGGAAGGCTCCGACGTCAAGCGCAAGGCGGAGATGTATCTGAGCGAGCTCCAGCCGTGAGT
GGCGGCGGGCCGACCATGAT

Downstream 100 bases:

>100_bases
GGGGGGCCATGGTGAACGTGACGCGCTCTCAGGTGGTGGGCGGTGTGCTGGCGCTGCTGGCGGCCGGCGCGGTGCTGTAC
TTCTGGCCGCGGCAGCAGCT

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPGRKGMNESSLRELGMDLIEERQFERALAVFAEAVRRVPADHRSRMLAARCLAELGERERAVTAYHACAEGLLRRDYLL
SAMAACKLALDLAPNERRLKETLFRVHSRAVRNAPGRAVVPPPLPPETLYDGKVETDLMGLQGEELSSRAIEVLAATDPG
GAADPNSRPPLPLFAELDRDAFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAEVTRQMEGEARTLGFLGGGSIF
GEIALLTGAPPTATVSAVSDTEVFEIRREHLNAVAKSHPAVPQVLADFAQQRMARNLMATSPMFQTMPESERGALLRRFT
FRALQAREKVLVEGEHSPGLFLVLAGELVVQKEDPAGGVVTLGMLREGEVAGEISLLTGLRATATVAAARKTAAAFLERA
AFHELVTAVPDIRTYLEQLSDRRLKQIGEALRPAEIIDADELVLEPEAA

Sequences:

>Translated_449_residues
MPGRKGMNESSLRELGMDLIEERQFERALAVFAEAVRRVPADHRSRMLAARCLAELGERERAVTAYHACAEGLLRRDYLL
SAMAACKLALDLAPNERRLKETLFRVHSRAVRNAPGRAVVPPPLPPETLYDGKVETDLMGLQGEELSSRAIEVLAATDPG
GAADPNSRPPLPLFAELDRDAFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAEVTRQMEGEARTLGFLGGGSIF
GEIALLTGAPPTATVSAVSDTEVFEIRREHLNAVAKSHPAVPQVLADFAQQRMARNLMATSPMFQTMPESERGALLRRFT
FRALQAREKVLVEGEHSPGLFLVLAGELVVQKEDPAGGVVTLGMLREGEVAGEISLLTGLRATATVAAARKTAAAFLERA
AFHELVTAVPDIRTYLEQLSDRRLKQIGEALRPAEIIDADELVLEPEAA
>Mature_448_residues
PGRKGMNESSLRELGMDLIEERQFERALAVFAEAVRRVPADHRSRMLAARCLAELGERERAVTAYHACAEGLLRRDYLLS
AMAACKLALDLAPNERRLKETLFRVHSRAVRNAPGRAVVPPPLPPETLYDGKVETDLMGLQGEELSSRAIEVLAATDPGG
AADPNSRPPLPLFAELDRDAFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAEVTRQMEGEARTLGFLGGGSIFG
EIALLTGAPPTATVSAVSDTEVFEIRREHLNAVAKSHPAVPQVLADFAQQRMARNLMATSPMFQTMPESERGALLRRFTF
RALQAREKVLVEGEHSPGLFLVLAGELVVQKEDPAGGVVTLGMLREGEVAGEISLLTGLRATATVAAARKTAAAFLERAA
FHELVTAVPDIRTYLEQLSDRRLKQIGEALRPAEIIDADELVLEPEAA

Specific function: Unknown

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4758958, Length=267, Percent_Identity=21.3483146067416, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI5453978, Length=243, Percent_Identity=22.6337448559671, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI47132585, Length=258, Percent_Identity=22.8682170542636, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI10835242, Length=217, Percent_Identity=24.8847926267281, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI148612818, Length=217, Percent_Identity=24.8847926267281, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI47132583, Length=241, Percent_Identity=24.4813278008299, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI47132581, Length=241, Percent_Identity=24.4813278008299, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4506063, Length=241, Percent_Identity=24.4813278008299, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI258613977, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258613975, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258613973, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258613971, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258613969, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI38257139, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539610, Length=272, Percent_Identity=23.1617647058824, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17539608, Length=272, Percent_Identity=23.1617647058824, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71989393, Length=272, Percent_Identity=23.1617647058824, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25145047, Length=272, Percent_Identity=23.1617647058824, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322156, Length=240, Percent_Identity=24.5833333333333, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573932, Length=264, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573930, Length=264, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17647815, Length=264, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI161076490, Length=264, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076492, Length=258, Percent_Identity=24.4186046511628, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI62472300, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62472310, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28574654, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28574656, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62472279, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62472291, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24667745, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62472332, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221513359, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI62472322, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28574658, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48902; Mature: 48771

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRKGMNESSLRELGMDLIEERQFERALAVFAEAVRRVPADHRSRMLAARCLAELGERE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RAVTAYHACAEGLLRRDYLLSAMAACKLALDLAPNERRLKETLFRVHSRAVRNAPGRAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEC
PPPLPPETLYDGKVETDLMGLQGEELSSRAIEVLAATDPGGAADPNSRPPLPLFAELDRD
CCCCCCCCCCCCCCCHHHCCCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCHH
AFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAEVTRQMEGEARTLGFLGGGSIF
HHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHEEEEECCCHHH
GEIALLTGAPPTATVSAVSDTEVFEIRREHLNAVAKSHPAVPQVLADFAQQRMARNLMAT
HHHHEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
SPMFQTMPESERGALLRRFTFRALQAREKVLVEGEHSPGLFLVLAGELVVQKEDPAGGVV
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEEEECCCCCCEE
TLGMLREGEVAGEISLLTGLRATATVAAARKTAAAFLERAAFHELVTAVPDIRTYLEQLS
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRLKQIGEALRPAEIIDADELVLEPEAA
HHHHHHHHHHCCCHHHCCCHHHEECCCCC
>Mature Secondary Structure 
PGRKGMNESSLRELGMDLIEERQFERALAVFAEAVRRVPADHRSRMLAARCLAELGERE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RAVTAYHACAEGLLRRDYLLSAMAACKLALDLAPNERRLKETLFRVHSRAVRNAPGRAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEC
PPPLPPETLYDGKVETDLMGLQGEELSSRAIEVLAATDPGGAADPNSRPPLPLFAELDRD
CCCCCCCCCCCCCCCHHHCCCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCHH
AFVDLVRLMAWRRVKPEEAVSREGEPADSLYVLVAGKAEVTRQMEGEARTLGFLGGGSIF
HHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHEEEEECCCHHH
GEIALLTGAPPTATVSAVSDTEVFEIRREHLNAVAKSHPAVPQVLADFAQQRMARNLMAT
HHHHEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
SPMFQTMPESERGALLRRFTFRALQAREKVLVEGEHSPGLFLVLAGELVVQKEDPAGGVV
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCEEEEECCCCCCEE
TLGMLREGEVAGEISLLTGLRATATVAAARKTAAAFLERAAFHELVTAVPDIRTYLEQLS
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRLKQIGEALRPAEIIDADELVLEPEAA
HHHHHHHHHHCCCHHHCCCHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA