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The map label for this gene is xerD [H]

Identifier: 108758883

GI number: 108758883

Start: 4623262

End: 4624194

Strand: Reverse

Name: xerD [H]

Synonym: MXAN_3844

Alternate gene names: 108758883

Gene position: 4624194-4623262 (Counterclockwise)

Preceding gene: 108760986

Following gene: 108756886

Centisome position: 50.59

GC content: 69.35

Gene sequence:

>933_bases
ATGGAAGGACTGCTCGACGCGTTCATCGCCTTCATCCGCGCGGAGCGCGGACTGTCCGGCAAGACGGTGGACGCCTACGC
CGCGGACATCAACGTGTACTTCGAGGACCTGCGCTCCCGCGGCGTCTCAGACGTGACGCAGGCGCGGCAGGAGGACGTGT
CCGCGCACCTGTCCGCGCTGGGCAAGCGGGGCTTGGGCAAGCGCAGCCAGGCCCGTCACCTGGCGGCCCTGCGCGGCTTC
CACCGGTTCCTCGTCGCCGAGCGCATGGCGGACAAGGATCCGACGGAGGACCTGGACACGCCCCGCTCAGCCCGGAAGCT
GCCGTCGTTCCTCACCCTGGAAGAGGTGGAGCAGCTCTTGGCGGCCCCGGACGAGCGCACGTCCACGGGCGTGCGTGACA
AGGCCATGCTGGAGGTGCTGTACGCCACCGGCCTCCGCGTGAGTGAGCTGTGTGGGCTGGGCATCAACGACGTGCAGCTC
ACGGCGGGCTATCTGGTGGCGAAGGGCAAGGGCGCCAAGGAGCGGCTCGTCCCGCTGGGGAGCGTGGCCATCGAGAAGGT
CCAGGCATACCTGGCGGAGTCCCGGCCGGCGGTGCTGGGGCGGCGCAAGTCCCAGGCGTTGTTCGTCACGCCACGAGGCT
CTGGCTTCACGCGGCAGGGCTTCTGGAAGCTGCTCAAGCGGTACGCGCTGAAGGCGGGCATCTTGAAGCCGCTGTCTCCC
CACAAGCTGCGGCATTCGTTCGCCACGCACCTGGTGGAGCGTGGCGCGGACCTGCGCGCCGTCCAGCAGATGCTGGGGCA
CGCGGACCTCGCCACGACGCAAATCTATACCCACGTGAACGCCGCCCGGCTGCGGTCCGTGTACGACGAGTTCCACCCGC
GCAGCGATGTCTTCGTCCCCAAGGCGAAGAAGGCGCGGGCCGCCGCGCGATAG

Upstream 100 bases:

>100_bases
GGTGCAGGCGCTGGAGTCGGCGTCACCGGAGGGGGCGAGGGAGCCCCGGGCCTGAGCCGCTGAGTTGCCTCGCCGCGCGC
CTCCGGTAGCCTGCGCGGCG

Downstream 100 bases:

>100_bases
GGGTGGCAGCCCGGAGCCTCGGCGTCGTGGATGGAACGTTCCGTCCGCTGGCGCTCAGCTCCCCACGCCGTGGATGGGGA
GGCCGAACGGGTCCGTGTGG

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MEGLLDAFIAFIRAERGLSGKTVDAYAADINVYFEDLRSRGVSDVTQARQEDVSAHLSALGKRGLGKRSQARHLAALRGF
HRFLVAERMADKDPTEDLDTPRSARKLPSFLTLEEVEQLLAAPDERTSTGVRDKAMLEVLYATGLRVSELCGLGINDVQL
TAGYLVAKGKGAKERLVPLGSVAIEKVQAYLAESRPAVLGRRKSQALFVTPRGSGFTRQGFWKLLKRYALKAGILKPLSP
HKLRHSFATHLVERGADLRAVQQMLGHADLATTQIYTHVNAARLRSVYDEFHPRSDVFVPKAKKARAAAR

Sequences:

>Translated_310_residues
MEGLLDAFIAFIRAERGLSGKTVDAYAADINVYFEDLRSRGVSDVTQARQEDVSAHLSALGKRGLGKRSQARHLAALRGF
HRFLVAERMADKDPTEDLDTPRSARKLPSFLTLEEVEQLLAAPDERTSTGVRDKAMLEVLYATGLRVSELCGLGINDVQL
TAGYLVAKGKGAKERLVPLGSVAIEKVQAYLAESRPAVLGRRKSQALFVTPRGSGFTRQGFWKLLKRYALKAGILKPLSP
HKLRHSFATHLVERGADLRAVQQMLGHADLATTQIYTHVNAARLRSVYDEFHPRSDVFVPKAKKARAAAR
>Mature_310_residues
MEGLLDAFIAFIRAERGLSGKTVDAYAADINVYFEDLRSRGVSDVTQARQEDVSAHLSALGKRGLGKRSQARHLAALRGF
HRFLVAERMADKDPTEDLDTPRSARKLPSFLTLEEVEQLLAAPDERTSTGVRDKAMLEVLYATGLRVSELCGLGINDVQL
TAGYLVAKGKGAKERLVPLGSVAIEKVQAYLAESRPAVLGRRKSQALFVTPRGSGFTRQGFWKLLKRYALKAGILKPLSP
HKLRHSFATHLVERGADLRAVQQMLGHADLATTQIYTHVNAARLRSVYDEFHPRSDVFVPKAKKARAAAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=44.8630136986301, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=38.5665529010239, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1790768, Length=196, Percent_Identity=31.6326530612245, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790767, Length=184, Percent_Identity=29.3478260869565, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34183; Mature: 34183

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLLDAFIAFIRAERGLSGKTVDAYAADINVYFEDLRSRGVSDVTQARQEDVSAHLSAL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GKRGLGKRSQARHLAALRGFHRFLVAERMADKDPTEDLDTPRSARKLPSFLTLEEVEQLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
AAPDERTSTGVRDKAMLEVLYATGLRVSELCGLGINDVQLTAGYLVAKGKGAKERLVPLG
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCEEEECCCCCHHHHCCHH
SVAIEKVQAYLAESRPAVLGRRKSQALFVTPRGSGFTRQGFWKLLKRYALKAGILKPLSP
HHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCH
HKLRHSFATHLVERGADLRAVQQMLGHADLATTQIYTHVNAARLRSVYDEFHPRSDVFVP
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KAKKARAAAR
CCHHHHHCCC
>Mature Secondary Structure
MEGLLDAFIAFIRAERGLSGKTVDAYAADINVYFEDLRSRGVSDVTQARQEDVSAHLSAL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GKRGLGKRSQARHLAALRGFHRFLVAERMADKDPTEDLDTPRSARKLPSFLTLEEVEQLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
AAPDERTSTGVRDKAMLEVLYATGLRVSELCGLGINDVQLTAGYLVAKGKGAKERLVPLG
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCEEEECCCCCHHHHCCHH
SVAIEKVQAYLAESRPAVLGRRKSQALFVTPRGSGFTRQGFWKLLKRYALKAGILKPLSP
HHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCH
HKLRHSFATHLVERGADLRAVQQMLGHADLATTQIYTHVNAARLRSVYDEFHPRSDVFVP
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KAKKARAAAR
CCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]