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The map label for this gene is trpS [H]

Identifier: 108756886

GI number: 108756886

Start: 4620733

End: 4621776

Strand: Reverse

Name: trpS [H]

Synonym: MXAN_3842

Alternate gene names: 108756886

Gene position: 4621776-4620733 (Counterclockwise)

Preceding gene: 108758883

Following gene: 108763535

Centisome position: 50.57

GC content: 66.95

Gene sequence:

>1044_bases
ATGCGAATTCTTTCAGGAGTGCAGTCGTCCGGCAGGCTGCACATCGGCAACTACTACGGCGCGCTCCGCCAGTTCGTGCA
GCTCCAGGATGAAGGCGAGGGGTACTACTTCATCGCCAACCTGCACGCGCTCACCACCGTGAGGGATCCCAAGGCCGCGC
TGGCGCTGACGCGCGAGGCCGCCATGGCCTACCTGTCGCTGGGGTTGGATCCGAAGAAGGCCGTGCTCTTCCGGCAGAGC
GACGTGCGTGAGGTGCTGGAGCTGTACTGGATTCTGGGCACCGTGACGCCGCACGCGCACCTGGAGCGGGCCCACAGCTA
CAAGGACAAGGTGGCCAAGGGCATCAGCCCGGACTTCGGCCTCTTCGCCTACCCGGTACTGATGGCCGCCGACATCCTGC
TCTACAGCGCGGACTTCGTCCCGGTGGGCAAGGACCAGATTCAGCACATCGAGTTCGCGCGCGACTGGGCGGTGAAGTTC
AACACCCAGTACGTGCCCGGCTACGACCCGGCCGATCCGGAAGGCAAGGAGCGGGGCCATGCGCCCGGCATCCTCAAGCT
GCCCGCGGCGCGCATCCAGGAGACCACCCAGACGGTGCCCGGCGTCGACGGACAGAAGATGTCCAAGTCCTACGGGAACA
CCATCGAGCTCTTCGGGGACGAGAAGGAAATCAAGAAGCGGATCATGTCCATCAAGACGGACTCGACGCCGGTGGACGCG
CCCAAGCCGCTGCCCACGCAGTCGCCGCCGCCCGGGCTCGTCAGCGATGCGCCGCTCTACGACTTGCTGAAGCTGATGCT
TCCCGAGTCCGAGTTCGCCGAGGTGGACGCCACCTGGAGGGCGGGCGGGAAGGGCTACGGCGACTACAAGAAGAAGCTCC
TGGAGGCCTACCATGCGGCCTTTGGCCCGGCCCGTCAGCGGTACGCCGAACTGGCGGCCGACCCGGGCGAGGTGGAGCGC
ATCCTCCAGGACGGCGCCAGCCGGGCCAGGGCCGAGGCGAGCCGCCTCATGGACCGGGTCCGCAAGGCCGTGGGAGTCCC
ATGA

Upstream 100 bases:

>100_bases
GGCGCAGGACACGGGCAACGGACGGTTGCAGGGCCGCGTCGGGTGTGCGAACGAGCCCCGTCCGATTCCCGATTCCGCCC
AACCGAATCAGAGCGAGTCC

Downstream 100 bases:

>100_bases
GTCCGTGTGCCTGAACGGGCTTTCACTGCCGATTGTTTGACCCTCCTGGGGGGCACTGGTATGGGTGTGTGTCCTCCAGG
CTCGTGCCCGCTGCCTAAGA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRILSGVQSSGRLHIGNYYGALRQFVQLQDEGEGYYFIANLHALTTVRDPKAALALTREAAMAYLSLGLDPKKAVLFRQS
DVREVLELYWILGTVTPHAHLERAHSYKDKVAKGISPDFGLFAYPVLMAADILLYSADFVPVGKDQIQHIEFARDWAVKF
NTQYVPGYDPADPEGKERGHAPGILKLPAARIQETTQTVPGVDGQKMSKSYGNTIELFGDEKEIKKRIMSIKTDSTPVDA
PKPLPTQSPPPGLVSDAPLYDLLKLMLPESEFAEVDATWRAGGKGYGDYKKKLLEAYHAAFGPARQRYAELAADPGEVER
ILQDGASRARAEASRLMDRVRKAVGVP

Sequences:

>Translated_347_residues
MRILSGVQSSGRLHIGNYYGALRQFVQLQDEGEGYYFIANLHALTTVRDPKAALALTREAAMAYLSLGLDPKKAVLFRQS
DVREVLELYWILGTVTPHAHLERAHSYKDKVAKGISPDFGLFAYPVLMAADILLYSADFVPVGKDQIQHIEFARDWAVKF
NTQYVPGYDPADPEGKERGHAPGILKLPAARIQETTQTVPGVDGQKMSKSYGNTIELFGDEKEIKKRIMSIKTDSTPVDA
PKPLPTQSPPPGLVSDAPLYDLLKLMLPESEFAEVDATWRAGGKGYGDYKKKLLEAYHAAFGPARQRYAELAADPGEVER
ILQDGASRARAEASRLMDRVRKAVGVP
>Mature_347_residues
MRILSGVQSSGRLHIGNYYGALRQFVQLQDEGEGYYFIANLHALTTVRDPKAALALTREAAMAYLSLGLDPKKAVLFRQS
DVREVLELYWILGTVTPHAHLERAHSYKDKVAKGISPDFGLFAYPVLMAADILLYSADFVPVGKDQIQHIEFARDWAVKF
NTQYVPGYDPADPEGKERGHAPGILKLPAARIQETTQTVPGVDGQKMSKSYGNTIELFGDEKEIKKRIMSIKTDSTPVDA
PKPLPTQSPPPGLVSDAPLYDLLKLMLPESEFAEVDATWRAGGKGYGDYKKKLLEAYHAAFGPARQRYAELAADPGEVER
ILQDGASRARAEASRLMDRVRKAVGVP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=346, Percent_Identity=30.0578034682081, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI41352700, Length=165, Percent_Identity=42.4242424242424, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1789786, Length=347, Percent_Identity=35.7348703170029, Blast_Score=180, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71982800, Length=358, Percent_Identity=29.0502793296089, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71982793, Length=358, Percent_Identity=29.0502793296089, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=369, Percent_Identity=28.4552845528455, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24666151, Length=351, Percent_Identity=30.1994301994302, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38328; Mature: 38328

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILSGVQSSGRLHIGNYYGALRQFVQLQDEGEGYYFIANLHALTTVRDPKAALALTREA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHH
AMAYLSLGLDPKKAVLFRQSDVREVLELYWILGTVTPHAHLERAHSYKDKVAKGISPDFG
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
LFAYPVLMAADILLYSADFVPVGKDQIQHIEFARDWAVKFNTQYVPGYDPADPEGKERGH
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCEECCCCCCCCCCCCCCCC
APGILKLPAARIQETTQTVPGVDGQKMSKSYGNTIELFGDEKEIKKRIMSIKTDSTPVDA
CCCEEECCHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
PKPLPTQSPPPGLVSDAPLYDLLKLMLPESEFAEVDATWRAGGKGYGDYKKKLLEAYHAA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHH
FGPARQRYAELAADPGEVERILQDGASRARAEASRLMDRVRKAVGVP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILSGVQSSGRLHIGNYYGALRQFVQLQDEGEGYYFIANLHALTTVRDPKAALALTREA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHH
AMAYLSLGLDPKKAVLFRQSDVREVLELYWILGTVTPHAHLERAHSYKDKVAKGISPDFG
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCH
LFAYPVLMAADILLYSADFVPVGKDQIQHIEFARDWAVKFNTQYVPGYDPADPEGKERGH
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCEECCCCCCCCCCCCCCCC
APGILKLPAARIQETTQTVPGVDGQKMSKSYGNTIELFGDEKEIKKRIMSIKTDSTPVDA
CCCEEECCHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
PKPLPTQSPPPGLVSDAPLYDLLKLMLPESEFAEVDATWRAGGKGYGDYKKKLLEAYHAA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHH
FGPARQRYAELAADPGEVERILQDGASRARAEASRLMDRVRKAVGVP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]