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The map label for this gene is coaE [H]

Identifier: 108758833

GI number: 108758833

Start: 3548022

End: 3548618

Strand: Reverse

Name: coaE [H]

Synonym: MXAN_3021

Alternate gene names: 108758833

Gene position: 3548618-3548022 (Counterclockwise)

Preceding gene: 108762688

Following gene: 108757742

Centisome position: 38.83

GC content: 72.03

Gene sequence:

>597_bases
GTGCACGTCTTCGGACTGACGGGAGGCATCGCCTCCGGCAAGAGCACCGTGACGCGCATCCTGCGGGAGCTGGGCGCGGA
GGTGCTGGACGCGGACGTGATTGCCCGCGAGGTGGTGGAACCGGGCACGCCCGGGCTGGCCGCGGTGGCGGCGCGCTTCC
CCGGCGTGGTGGGCTCGGACGGCCGGCTGGACCGGGTGAGGCTGGGCGCACGCGTCTTCGGGGACCCCGCAGAGCGCGCC
GCGCTCAATGACATCACCCACCCGCTGGTGCGTCAGGCCTTCATGGACAAGCTCCAGGCGCTGGAGGAACGGGGCGTGGC
GCGCGTCATCTACGACGTGCCCCTGCTCATCGAAAGCGGCATGCACACCTGGATGGAGGCCGTGGCGGTGGTGTGGGTGC
CCCGCGCAATGCAGAAGGCCCGGCTGATGTCGCGCGACGGGCTGGACTCCGACGCCGCCGACGCCCGGCTGGCTGCCCAG
CTTCCCCTGGACGACAAGCGCGCCCATGCCACCTGGGTCATCGACAACAGTGGGGACCTGGCCTCCACCCGCGCCCAGGT
TGAAGCGATGTGGCGCGCCATGCTCGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TACCCCCGCCTGGGCCTGGCCATCTTCTTCAACGAGGACGGCAAGACGGTTCAGTCGTTGACGTTCACCACGCAGAAGGC
CGCGAAGTAAGGCCCCGCCC

Downstream 100 bases:

>100_bases
GCGCCGGGTATGCTGCGCGCCGCATGAGCGAGACGCGCAAGAAGGCCACGGCCGGAACGTACTTCATCACCGGCTACCCG
GGATTCATCGGCAAGCGGCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MHVFGLTGGIASGKSTVTRILRELGAEVLDADVIAREVVEPGTPGLAAVAARFPGVVGSDGRLDRVRLGARVFGDPAERA
ALNDITHPLVRQAFMDKLQALEERGVARVIYDVPLLIESGMHTWMEAVAVVWVPRAMQKARLMSRDGLDSDAADARLAAQ
LPLDDKRAHATWVIDNSGDLASTRAQVEAMWRAMLARG

Sequences:

>Translated_198_residues
MHVFGLTGGIASGKSTVTRILRELGAEVLDADVIAREVVEPGTPGLAAVAARFPGVVGSDGRLDRVRLGARVFGDPAERA
ALNDITHPLVRQAFMDKLQALEERGVARVIYDVPLLIESGMHTWMEAVAVVWVPRAMQKARLMSRDGLDSDAADARLAAQ
LPLDDKRAHATWVIDNSGDLASTRAQVEAMWRAMLARG
>Mature_198_residues
MHVFGLTGGIASGKSTVTRILRELGAEVLDADVIAREVVEPGTPGLAAVAARFPGVVGSDGRLDRVRLGARVFGDPAERA
ALNDITHPLVRQAFMDKLQALEERGVARVIYDVPLLIESGMHTWMEAVAVVWVPRAMQKARLMSRDGLDSDAADARLAAQ
LPLDDKRAHATWVIDNSGDLASTRAQVEAMWRAMLARG

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=43.3862433862434, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=43.3862433862434, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI110227607, Length=201, Percent_Identity=30.3482587064677, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI110227605, Length=201, Percent_Identity=30.3482587064677, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI110227603, Length=201, Percent_Identity=30.3482587064677, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI110227601, Length=201, Percent_Identity=30.3482587064677, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI205277394, Length=201, Percent_Identity=30.3482587064677, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1786292, Length=178, Percent_Identity=40.4494382022472, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=207, Percent_Identity=35.7487922705314, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25143409, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=35, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644728, Length=196, Percent_Identity=33.6734693877551, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24658602, Length=196, Percent_Identity=34.6938775510204, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21344; Mature: 21344

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVFGLTGGIASGKSTVTRILRELGAEVLDADVIAREVVEPGTPGLAAVAARFPGVVGSD
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GRLDRVRLGARVFGDPAERAALNDITHPLVRQAFMDKLQALEERGVARVIYDVPLLIESG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MHTWMEAVAVVWVPRAMQKARLMSRDGLDSDAADARLAAQLPLDDKRAHATWVIDNSGDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCH
ASTRAQVEAMWRAMLARG
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHVFGLTGGIASGKSTVTRILRELGAEVLDADVIAREVVEPGTPGLAAVAARFPGVVGSD
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GRLDRVRLGARVFGDPAERAALNDITHPLVRQAFMDKLQALEERGVARVIYDVPLLIESG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
MHTWMEAVAVVWVPRAMQKARLMSRDGLDSDAADARLAAQLPLDDKRAHATWVIDNSGDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCH
ASTRAQVEAMWRAMLARG
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA