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The map label for this gene is kinA [H]

Identifier: 108758648

GI number: 108758648

Start: 524750

End: 525478

Strand: Direct

Name: kinA [H]

Synonym: MXAN_0461

Alternate gene names: 108758648

Gene position: 524750-525478 (Clockwise)

Preceding gene: 108760318

Following gene: 108761939

Centisome position: 5.74

GC content: 71.74

Gene sequence:

>729_bases
ATGGCAGGCAGAGACCTCCAGGCGCGTGAGCGGGCGGCGGTGGCGGACGTGGTGGCCTCCACCCTGCGGCACGACCTGCG
CAACAAGCTGGCCAGCATCCGCAACGCCTCGTTCTACTTGATGCGGCAGGTGAAGAAGACGGACCTCTGGAGCGCGGACC
CGCGCGTGGAGACCTTCTTCCAGCTCATCGAAAAAGAGCTGACGTCCGCCGAGGACGTGCTCTCCAAGCGCGCGCCGCCG
CCCACCGGTGGCACGCGTCCCCGGTGCAGTGCCCGCGAAGGCGTGGAGCGCGCGCTCGCCGAGGCCCAGGTGCCGCCGTC
GGTGGAGGTGGTGCGCGACCTGAAGGAGCAGGGCGGCGTCCCGTTGGAGGTGGAGGACCTGGCGCTGCTGGTGCGCTGCC
TCGTGGACAACGCGCTGGAGGCCATGCCGCGCGGCGGGACGCTCACGGTGCGCACGCGCGACGCCGAAAGCGGCGTGTGC
CTGCGTGTGGAGGACACCGGAGAGGGCCTGGCGGCGGAGGCGTACTCGCGCGCCCTGGAGCCCTTCTTCACCACGCGGCC
CCACCACGCCGGGCTGGGGCTGAGCATCGTCCACCGGACGGCCGTGCGGCACGGCTGGCAGTTGGACCTGGGCGCGGGCC
CCTCCGGGGGCACCTACGTGGAAATCCAATTCACGGGCCTGGAGGCGGGGGCCCATGACCGGAATGACGTGACTCGGGGG
AGCAAGTGA

Upstream 100 bases:

>100_bases
GTGCATGACCAAGCCGGTACCGTTGCGCGAGCTGGTGCAGGCGATTGCACGGGTGCGAGGCCGGCCTCAACAAGGGCTGC
AAGGCGCGAGGATTTGACCC

Downstream 100 bases:

>100_bases
TGGAGACGAACTGGACGTTCGGGCGTTGCCTGCTGCTCGTGGAAGACGACCCTTCCAACCGGATGACGCTGTCCGCGCTT
TTGGAGGATGCGGGCTTCGC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAGRDLQARERAAVADVVASTLRHDLRNKLASIRNASFYLMRQVKKTDLWSADPRVETFFQLIEKELTSAEDVLSKRAPP
PTGGTRPRCSAREGVERALAEAQVPPSVEVVRDLKEQGGVPLEVEDLALLVRCLVDNALEAMPRGGTLTVRTRDAESGVC
LRVEDTGEGLAAEAYSRALEPFFTTRPHHAGLGLSIVHRTAVRHGWQLDLGAGPSGGTYVEIQFTGLEAGAHDRNDVTRG
SK

Sequences:

>Translated_242_residues
MAGRDLQARERAAVADVVASTLRHDLRNKLASIRNASFYLMRQVKKTDLWSADPRVETFFQLIEKELTSAEDVLSKRAPP
PTGGTRPRCSAREGVERALAEAQVPPSVEVVRDLKEQGGVPLEVEDLALLVRCLVDNALEAMPRGGTLTVRTRDAESGVC
LRVEDTGEGLAAEAYSRALEPFFTTRPHHAGLGLSIVHRTAVRHGWQLDLGAGPSGGTYVEIQFTGLEAGAHDRNDVTRG
SK
>Mature_241_residues
AGRDLQARERAAVADVVASTLRHDLRNKLASIRNASFYLMRQVKKTDLWSADPRVETFFQLIEKELTSAEDVLSKRAPPP
TGGTRPRCSAREGVERALAEAQVPPSVEVVRDLKEQGGVPLEVEDLALLVRCLVDNALEAMPRGGTLTVRTRDAESGVCL
RVEDTGEGLAAEAYSRALEPFFTTRPHHAGLGLSIVHRTAVRHGWQLDLGAGPSGGTYVEIQFTGLEAGAHDRNDVTRGS
K

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 26317; Mature: 26186

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRDLQARERAAVADVVASTLRHDLRNKLASIRNASFYLMRQVKKTDLWSADPRVETFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHH
QLIEKELTSAEDVLSKRAPPPTGGTRPRCSAREGVERALAEAQVPPSVEVVRDLKEQGGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PLEVEDLALLVRCLVDNALEAMPRGGTLTVRTRDAESGVCLRVEDTGEGLAAEAYSRALE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
PFFTTRPHHAGLGLSIVHRTAVRHGWQLDLGAGPSGGTYVEIQFTGLEAGAHDRNDVTRG
HHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCC
SK
CC
>Mature Secondary Structure 
AGRDLQARERAAVADVVASTLRHDLRNKLASIRNASFYLMRQVKKTDLWSADPRVETFF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHH
QLIEKELTSAEDVLSKRAPPPTGGTRPRCSAREGVERALAEAQVPPSVEVVRDLKEQGGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PLEVEDLALLVRCLVDNALEAMPRGGTLTVRTRDAESGVCLRVEDTGEGLAAEAYSRALE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHH
PFFTTRPHHAGLGLSIVHRTAVRHGWQLDLGAGPSGGTYVEIQFTGLEAGAHDRNDVTRG
HHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCC
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]