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The map label for this gene is 108758494

Identifier: 108758494

GI number: 108758494

Start: 6568611

End: 6570320

Strand: Direct

Name: 108758494

Synonym: MXAN_5269

Alternate gene names: NA

Gene position: 6568611-6570320 (Clockwise)

Preceding gene: 108757695

Following gene: 108760284

Centisome position: 71.87

GC content: 64.5

Gene sequence:

>1710_bases
TTGGCGACCCGGAGTGCGTCTGGGCATGAACGAGCGCAATGGATCGCGAACAGACGCGGATCGCCGGCCATCGCATCGTC
CACGACGCGCAATGCCAAGGAGCATTTCATGTCGAAATCGAATCAGTCCGCGCCGACCCTTTCTCGCCGCAGCCTGTTAC
CAACACTCGCCGCGCTCGCCCTGGCTGTCGCCGCGCCGGATGCCAGCGCGTACTCGGCGATCTACGGCGGCGGCCCGTTC
TATTCCGGCGGGACCGCGGTGATGAACGACCTGCGCGGCTCGGGTTTCACCACGGTCATCCTGTGGAGCTTCCACATCGA
GGAGAACGGTGACCTGATCTACAACGACATTCCAGTGGTCAAGAACGGCGCCTACATGGGCGACCCTGCCTGGCCGACCC
GACTGGCCACACTGAAGACCGCGCCGACCTCGGTCAATCGCATCGAGGTGTCGATCGGTGCCTGGGGTGTTCCGGACTTC
GAACGCATGATTCGACTGGTCAACGGCACCGCGCCCGGCTGCGGCACCACCATCGTCTGCGGGACCGGAAGCAACAGCAT
CCTGTACAGGAACTTCCAGGCGCTGAAGGCCGCCACCGGCGCCGACGCCGTGAACTTCGACGACGAAAGCGCCTATGACC
TGGCCCCAACCACGACCTTCAGCCAGATGCTCATCGGGATGGGTTACAAGATCACCTTCGCACCGTACACGCAGCAGACG
TTCTGGCGGAACCTCAGGAACAACCTCGGCAGCGCCGTCGATAGAATCTACCTGCAAGTGTACGCCGGCGGCGCCGGCAA
CAACCCAGCGAGTTGGAACACCGCCATGGGCATGACTGTCGCCCCCGGCTTGTGGTCCAGGAATGGCAGCGGCTGCGCGT
CGGGCGACAGCCCGGCCACGGTGCAGACCCGGATGAGCAACTGGAAGACCAGCGCCGGCATCAGCGGCGGCTTCATGTGG
TTGTACGACGACATCCAGCAGTGCAGCGCGCAGGGGACGAGCGCGCAGTATGCGGCGGCAATCAACACCGCCGTCAGCGG
CAACACCCCGCCGGTGGCGAACTTCGGTGTCACCGTCAGCGGCCTCACCGCGACCTTCAGTGATGCGTCCACCGACGCGG
ACGGAACCATCGCCTCGCGCAGTTGGAATTTCGGCGACGGCAGCACCTCCACCGCGACCAACCCTTCACGCACCTATGCA
AGCGCCGGCAACTACAACGTCACCCTGACCGTCACCGACAATGGCGGCGCCAGTCATACGAAGTCCCAGGCGGTGTCCGT
CGGTTCGGGCTACGCCAATCTGGCGTTGAACAGGCCCACCACCAGTTCAGCCCCCTGCAACAGCACCGAATCGGCCGCCA
AGGCGGTCAACGGCAGCGTCTCGGGCGGCACCACCGACAAGTTCTGCTCACTGACCTCGCCGGCGTGGATACAGGTCGAC
CTCGGTACGGCGCAGACAGTCAGCAGCTTCACGCTCCAGCACGCGGGGGCGGGCGGTGAATCGACGGCCTGGAACAGCAG
GGCATTCACCATCCAGACGTCGAGCAACGGCTCCACTTGGAGCACGCCCGTCACGGTGAGCAACAACACTGGCAGCACTT
CGACCCATGCAATCACGGCGACGCCGGCGCGTTACATCCGGCTCAACGTGACGACGCCGACTCAGAACAGCGACCCAGCG
ACGCGAATCTACGAGTTCGAAGTTCGCTGA

Upstream 100 bases:

>100_bases
CCGGGCAGACATTCGCGATCAAACGTTCTTGCCTGACTTGAATCGCCCCAAAGATTGACAGACTGGAGTCGCCACTCGCA
ATCTCGGCCCGTCGCTGTCA

Downstream 100 bases:

>100_bases
ACGGTCGGTAACGAAGCCGGCCCTCGACACCACGAGGGTCGGCTTCGTGCCTGTGCCTGCTCCAAGCAGGCATTGACGGG
CCCCATCTACGCGGACATCA

Product: lysyl endopeptidase domain-containing protein

Products: NA

Alternate protein names: API; Lysyl endopeptidase; Protease I [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MATRSASGHERAQWIANRRGSPAIASSTTRNAKEHFMSKSNQSAPTLSRRSLLPTLAALALAVAAPDASAYSAIYGGGPF
YSGGTAVMNDLRGSGFTTVILWSFHIEENGDLIYNDIPVVKNGAYMGDPAWPTRLATLKTAPTSVNRIEVSIGAWGVPDF
ERMIRLVNGTAPGCGTTIVCGTGSNSILYRNFQALKAATGADAVNFDDESAYDLAPTTTFSQMLIGMGYKITFAPYTQQT
FWRNLRNNLGSAVDRIYLQVYAGGAGNNPASWNTAMGMTVAPGLWSRNGSGCASGDSPATVQTRMSNWKTSAGISGGFMW
LYDDIQQCSAQGTSAQYAAAINTAVSGNTPPVANFGVTVSGLTATFSDASTDADGTIASRSWNFGDGSTSTATNPSRTYA
SAGNYNVTLTVTDNGGASHTKSQAVSVGSGYANLALNRPTTSSAPCNSTESAAKAVNGSVSGGTTDKFCSLTSPAWIQVD
LGTAQTVSSFTLQHAGAGGESTAWNSRAFTIQTSSNGSTWSTPVTVSNNTGSTSTHAITATPARYIRLNVTTPTQNSDPA
TRIYEFEVR

Sequences:

>Translated_569_residues
MATRSASGHERAQWIANRRGSPAIASSTTRNAKEHFMSKSNQSAPTLSRRSLLPTLAALALAVAAPDASAYSAIYGGGPF
YSGGTAVMNDLRGSGFTTVILWSFHIEENGDLIYNDIPVVKNGAYMGDPAWPTRLATLKTAPTSVNRIEVSIGAWGVPDF
ERMIRLVNGTAPGCGTTIVCGTGSNSILYRNFQALKAATGADAVNFDDESAYDLAPTTTFSQMLIGMGYKITFAPYTQQT
FWRNLRNNLGSAVDRIYLQVYAGGAGNNPASWNTAMGMTVAPGLWSRNGSGCASGDSPATVQTRMSNWKTSAGISGGFMW
LYDDIQQCSAQGTSAQYAAAINTAVSGNTPPVANFGVTVSGLTATFSDASTDADGTIASRSWNFGDGSTSTATNPSRTYA
SAGNYNVTLTVTDNGGASHTKSQAVSVGSGYANLALNRPTTSSAPCNSTESAAKAVNGSVSGGTTDKFCSLTSPAWIQVD
LGTAQTVSSFTLQHAGAGGESTAWNSRAFTIQTSSNGSTWSTPVTVSNNTGSTSTHAITATPARYIRLNVTTPTQNSDPA
TRIYEFEVR
>Mature_568_residues
ATRSASGHERAQWIANRRGSPAIASSTTRNAKEHFMSKSNQSAPTLSRRSLLPTLAALALAVAAPDASAYSAIYGGGPFY
SGGTAVMNDLRGSGFTTVILWSFHIEENGDLIYNDIPVVKNGAYMGDPAWPTRLATLKTAPTSVNRIEVSIGAWGVPDFE
RMIRLVNGTAPGCGTTIVCGTGSNSILYRNFQALKAATGADAVNFDDESAYDLAPTTTFSQMLIGMGYKITFAPYTQQTF
WRNLRNNLGSAVDRIYLQVYAGGAGNNPASWNTAMGMTVAPGLWSRNGSGCASGDSPATVQTRMSNWKTSAGISGGFMWL
YDDIQQCSAQGTSAQYAAAINTAVSGNTPPVANFGVTVSGLTATFSDASTDADGTIASRSWNFGDGSTSTATNPSRTYAS
AGNYNVTLTVTDNGGASHTKSQAVSVGSGYANLALNRPTTSSAPCNSTESAAKAVNGSVSGGTTDKFCSLTSPAWIQVDL
GTAQTVSSFTLQHAGAGGESTAWNSRAFTIQTSSNGSTWSTPVTVSNNTGSTSTHAITATPARYIRLNVTTPTQNSDPAT
RIYEFEVR

Specific function: Unknown

COG id: COG3291

COG function: function code R; FOG: PKD repeat

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PKD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR017323
- InterPro:   IPR009003
- InterPro:   IPR022409
- InterPro:   IPR000601
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00801 PKD [H]

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 59392; Mature: 59261

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50022 FA58C_3 ; PS50093 PKD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRSASGHERAQWIANRRGSPAIASSTTRNAKEHFMSKSNQSAPTLSRRSLLPTLAALA
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LAVAAPDASAYSAIYGGGPFYSGGTAVMNDLRGSGFTTVILWSFHIEENGDLIYNDIPVV
HHHCCCCCHHHHEEECCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCCEE
KNGAYMGDPAWPTRLATLKTAPTSVNRIEVSIGAWGVPDFERMIRLVNGTAPGCGTTIVC
ECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEE
GTGSNSILYRNFQALKAATGADAVNFDDESAYDLAPTTTFSQMLIGMGYKITFAPYTQQT
ECCCCCEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHH
FWRNLRNNLGSAVDRIYLQVYAGGAGNNPASWNTAMGMTVAPGLWSRNGSGCASGDSPAT
HHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCE
VQTRMSNWKTSAGISGGFMWLYDDIQQCSAQGTSAQYAAAINTAVSGNTPPVANFGVTVS
EEEHHHCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEHHCCCCCCCCCCCCEEEE
GLTATFSDASTDADGTIASRSWNFGDGSTSTATNPSRTYASAGNYNVTLTVTDNGGASHT
CEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHEECCCCEEEEEEEECCCCCCCC
KSQAVSVGSGYANLALNRPTTSSAPCNSTESAAKAVNGSVSGGTTDKFCSLTSPAWIQVD
HHHEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHEEECCCCCEEEEE
LGTAQTVSSFTLQHAGAGGESTAWNSRAFTIQTSSNGSTWSTPVTVSNNTGSTSTHAITA
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEECCEEEEECCCCCCCCEEEEE
TPARYIRLNVTTPTQNSDPATRIYEFEVR
CCCEEEEEEEECCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
ATRSASGHERAQWIANRRGSPAIASSTTRNAKEHFMSKSNQSAPTLSRRSLLPTLAALA
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LAVAAPDASAYSAIYGGGPFYSGGTAVMNDLRGSGFTTVILWSFHIEENGDLIYNDIPVV
HHHCCCCCHHHHEEECCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCCEE
KNGAYMGDPAWPTRLATLKTAPTSVNRIEVSIGAWGVPDFERMIRLVNGTAPGCGTTIVC
ECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEE
GTGSNSILYRNFQALKAATGADAVNFDDESAYDLAPTTTFSQMLIGMGYKITFAPYTQQT
ECCCCCEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHH
FWRNLRNNLGSAVDRIYLQVYAGGAGNNPASWNTAMGMTVAPGLWSRNGSGCASGDSPAT
HHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCE
VQTRMSNWKTSAGISGGFMWLYDDIQQCSAQGTSAQYAAAINTAVSGNTPPVANFGVTVS
EEEHHHCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEHHCCCCCCCCCCCCEEEE
GLTATFSDASTDADGTIASRSWNFGDGSTSTATNPSRTYASAGNYNVTLTVTDNGGASHT
CEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHEECCCCEEEEEEEECCCCCCCC
KSQAVSVGSGYANLALNRPTTSSAPCNSTESAAKAVNGSVSGGTTDKFCSLTSPAWIQVD
HHHEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHEEECCCCCEEEEE
LGTAQTVSSFTLQHAGAGGESTAWNSRAFTIQTSSNGSTWSTPVTVSNNTGSTSTHAITA
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEECCEEEEECCCCCCCCEEEEE
TPARYIRLNVTTPTQNSDPATRIYEFEVR
CCCEEEEEEEECCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2684982; 2492988 [H]