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The map label for this gene is zraR [H]

Identifier: 108758443

GI number: 108758443

Start: 3392717

End: 3394516

Strand: Direct

Name: zraR [H]

Synonym: MXAN_2902

Alternate gene names: 108758443

Gene position: 3392717-3394516 (Clockwise)

Preceding gene: 108756838

Following gene: 108756779

Centisome position: 37.12

GC content: 72.78

Gene sequence:

>1800_bases
GTGGTGGTCATGACGCGGCCTGTGTCCGCCTACGCCCCTCGAAGCGAACGCAAGCCGTTGTACGTGAAGGTGGTGACGCA
GCCCGCGCTCCATGGGTGCTGGGCCGTCAACATCAGTGAGACGGGCATCGGGCTCATCGCCACGCCGCACACGCCGTCCG
AAGGGCCGCGTGAGGGCGAGGACGTGGAGCTGTCGTTCTCCCTTCCGGACTCTGGTGAGCACATCCGCGTGCGCGGCGTG
GTGCGCTGGCGTCACGACGCGTCCGGCGCGGTGGCGGCCATGGGCGTGAGCTTCCGCGCCTTCGAGGAAGCGGACGGCGT
GAAGCTGGCGCGCTACCTCGCCTCGTCGCACCTCCAGGTGGTGGTGGCCTTCGCCACCGAGCAGGAGTCGCGCGCGGTGA
CGGCCGCGCTGGAAGGGGTGGCCCAGCTCCACTTCGCCGCCAGCCCGTCGGATGCCCACGCGCTGGTGACGCGCGGGGAC
GCGGCGTGCCTGGTGGTGTGCGGTCAGGACGAGGAGCAGGCCCTGGCCCTGGTGGAGTCCCTGGCCGCCCGCCGCGCCGA
TGCGGACCCTTCCGGCGCGGGGCCACCCAGTGACCTGGCATCGCGAATCGTCTACTGCGCGCCGGCCGCGCCGGAGCGGC
TGGTGGCCCTCTTCAACGACGGGCGCATCTTCCGCGCGCTCGGGCCTTCACCCACGCGGGAGGCCCTGCACCAGGCGGTG
CTTCAAGCGGGGCGTGAGCACGGCGTGCGCACCGAACAGTGGCGCATGGCGCTGGAACTGGAGCGCAGCTTGCTGCGCGA
GCGCGCCCTGTCGCAGAAGCTGCCGCCGGCCCCCGGCGGGCGCGGCGGGGATGAGGTGGGCTTCCGCAGCGCCGCCATGC
AGCGGGTGATGGAGCTGGTGCGCCTGGTGGCGCCCCACCGCGTGGCCGTGCTGCTCCAAGGCGAGACGGGCACGGGCAAG
GAGGTGCTGGCGCGCATCCTCCACCGGCTCAGTGGCCGGGGGGACGTGCCGCTCGTGGTGCAGGACTGCGGCGCGCTGTC
GGAGACGCTGCTGGAGAGCGAGCTCTTCGGCCACGTGAAGGGCTCCTTCACGGGCGCGGTGGCGGACCACCCCGGGCTCT
TCGTGCTCGCCAACGGCGGCACCATCTTCCTGGACGAAATCGAGAACACCACCGCCAACCTCCAGGCCAAGCTCCTCCGC
GTGCTGGAGACGGGGGACGTGCGTCCGGTGGGCGGCACCCAGGTGCGCCACGTGGACGTGCGCGTGGTGGCCGCCAGCAA
CAAGGACATGGGCGAGGAAGTGCGCGCCGGCCGCTTCCGCGCGGACCTCTTCTACCGGCTCAACAGCTTCACCGTGGACA
TCCCCCCGCTGCGGGACAGGCCGGAGGACGTTCCGGAGCTGGCGCTCTACTTCCTGGAGTTGTTCAACCGCACCTTGCGC
CGCTCAGCCAGCGGCATCGCGCCGGACGCGGTGGACGCGTTGCGGGCCTACGCCTGGCCGGGCAACGTGCGCGAGCTGCG
CAACGTCATGGAGCGCTCGGTGCTGCTCTCCCGCCCGGGCGAGGTGGTGTCGCGGCGGCTGCTGCCGCCGGTGCTGGGCT
CCACCCTGGCCCTGCGCAACGAGCCGGGTGGGGATGGCTCGCTGCGCGCGCGGTTGGATCGGGTGGAGCGGGAGTTCATC
CGCGAGGCCCTGGAGCGCCACGGCGGGGTGCTGCGGCGCGCGGCCGTGGCGCTGGGGATGGACCCGGTGACGCTGGGCCG
GCGGGTCCGGCGCCACGGCTTGTGGAAAGGAGACAGCTAG

Upstream 100 bases:

>100_bases
CCGGTCGTTCATGACCTGTACCTACATCCAGGTCGAGTGATGGCTGGCGAATCTTCTAACGTCGCAAATTGTCAACGTCG
CTTCATCCCTCAAGTAGACT

Downstream 100 bases:

>100_bases
GCCTTGCGCCTCAGTGGGCGCGAATCCACTGGAGCATGGGCTTCCAGACGCGCATTCGCGCGTCGTCCGCCAGGAACAGG
TCCGCGTGCCCGTAGTCCAG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MVVMTRPVSAYAPRSERKPLYVKVVTQPALHGCWAVNISETGIGLIATPHTPSEGPREGEDVELSFSLPDSGEHIRVRGV
VRWRHDASGAVAAMGVSFRAFEEADGVKLARYLASSHLQVVVAFATEQESRAVTAALEGVAQLHFAASPSDAHALVTRGD
AACLVVCGQDEEQALALVESLAARRADADPSGAGPPSDLASRIVYCAPAAPERLVALFNDGRIFRALGPSPTREALHQAV
LQAGREHGVRTEQWRMALELERSLLRERALSQKLPPAPGGRGGDEVGFRSAAMQRVMELVRLVAPHRVAVLLQGETGTGK
EVLARILHRLSGRGDVPLVVQDCGALSETLLESELFGHVKGSFTGAVADHPGLFVLANGGTIFLDEIENTTANLQAKLLR
VLETGDVRPVGGTQVRHVDVRVVAASNKDMGEEVRAGRFRADLFYRLNSFTVDIPPLRDRPEDVPELALYFLELFNRTLR
RSASGIAPDAVDALRAYAWPGNVRELRNVMERSVLLSRPGEVVSRRLLPPVLGSTLALRNEPGGDGSLRARLDRVEREFI
REALERHGGVLRRAAVALGMDPVTLGRRVRRHGLWKGDS

Sequences:

>Translated_599_residues
MVVMTRPVSAYAPRSERKPLYVKVVTQPALHGCWAVNISETGIGLIATPHTPSEGPREGEDVELSFSLPDSGEHIRVRGV
VRWRHDASGAVAAMGVSFRAFEEADGVKLARYLASSHLQVVVAFATEQESRAVTAALEGVAQLHFAASPSDAHALVTRGD
AACLVVCGQDEEQALALVESLAARRADADPSGAGPPSDLASRIVYCAPAAPERLVALFNDGRIFRALGPSPTREALHQAV
LQAGREHGVRTEQWRMALELERSLLRERALSQKLPPAPGGRGGDEVGFRSAAMQRVMELVRLVAPHRVAVLLQGETGTGK
EVLARILHRLSGRGDVPLVVQDCGALSETLLESELFGHVKGSFTGAVADHPGLFVLANGGTIFLDEIENTTANLQAKLLR
VLETGDVRPVGGTQVRHVDVRVVAASNKDMGEEVRAGRFRADLFYRLNSFTVDIPPLRDRPEDVPELALYFLELFNRTLR
RSASGIAPDAVDALRAYAWPGNVRELRNVMERSVLLSRPGEVVSRRLLPPVLGSTLALRNEPGGDGSLRARLDRVEREFI
REALERHGGVLRRAAVALGMDPVTLGRRVRRHGLWKGDS
>Mature_599_residues
MVVMTRPVSAYAPRSERKPLYVKVVTQPALHGCWAVNISETGIGLIATPHTPSEGPREGEDVELSFSLPDSGEHIRVRGV
VRWRHDASGAVAAMGVSFRAFEEADGVKLARYLASSHLQVVVAFATEQESRAVTAALEGVAQLHFAASPSDAHALVTRGD
AACLVVCGQDEEQALALVESLAARRADADPSGAGPPSDLASRIVYCAPAAPERLVALFNDGRIFRALGPSPTREALHQAV
LQAGREHGVRTEQWRMALELERSLLRERALSQKLPPAPGGRGGDEVGFRSAAMQRVMELVRLVAPHRVAVLLQGETGTGK
EVLARILHRLSGRGDVPLVVQDCGALSETLLESELFGHVKGSFTGAVADHPGLFVLANGGTIFLDEIENTTANLQAKLLR
VLETGDVRPVGGTQVRHVDVRVVAASNKDMGEEVRAGRFRADLFYRLNSFTVDIPPLRDRPEDVPELALYFLELFNRTLR
RSASGIAPDAVDALRAYAWPGNVRELRNVMERSVLLSRPGEVVSRRLLPPVLGSTLALRNEPGGDGSLRARLDRVEREFI
REALERHGGVLRRAAVALGMDPVTLGRRVRRHGLWKGDS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=332, Percent_Identity=44.578313253012, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87082117, Length=356, Percent_Identity=43.5393258426966, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=43.3021806853583, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1788550, Length=313, Percent_Identity=41.85303514377, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=43.2692307692308, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1789087, Length=348, Percent_Identity=40.2298850574713, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1788905, Length=327, Percent_Identity=38.8379204892966, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI1790299, Length=323, Percent_Identity=38.390092879257, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI87081872, Length=220, Percent_Identity=48.1818181818182, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1786524, Length=251, Percent_Identity=44.6215139442231, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=37.0967741935484, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=32.2368421052632, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789828, Length=258, Percent_Identity=34.1085271317829, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 64904; Mature: 64904

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMTRPVSAYAPRSERKPLYVKVVTQPALHGCWAVNISETGIGLIATPHTPSEGPREGE
CEEEECCCHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCC
DVELSFSLPDSGEHIRVRGVVRWRHDASGAVAAMGVSFRAFEEADGVKLARYLASSHLQV
CEEEEEECCCCCCEEEEEEEEEEECCCCCCEEECCCCHHHHHHCCCHHHHHHHHHCCEEE
VVAFATEQESRAVTAALEGVAQLHFAASPSDAHALVTRGDAACLVVCGQDEEQALALVES
EEEEECCCHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHH
LAARRADADPSGAGPPSDLASRIVYCAPAAPERLVALFNDGRIFRALGPSPTREALHQAV
HHHHCCCCCCCCCCCHHHHHHHEEEECCCCHHHEEEEECCCEEEEECCCCHHHHHHHHHH
LQAGREHGVRTEQWRMALELERSLLRERALSQKLPPAPGGRGGDEVGFRSAAMQRVMELV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLVAPHRVAVLLQGETGTGKEVLARILHRLSGRGDVPLVVQDCGALSETLLESELFGHVK
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
GSFTGAVADHPGLFVLANGGTIFLDEIENTTANLQAKLLRVLETGDVRPVGGTQVRHVDV
CCCCEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
RVVAASNKDMGEEVRAGRFRADLFYRLNSFTVDIPPLRDRPEDVPELALYFLELFNRTLR
EEEEECCCCCHHHHHHCHHHHHHHEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RSASGIAPDAVDALRAYAWPGNVRELRNVMERSVLLSRPGEVVSRRLLPPVLGSTLALRN
HHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCEEECC
EPGGDGSLRARLDRVEREFIREALERHGGVLRRAAVALGMDPVTLGRRVRRHGLWKGDS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVVMTRPVSAYAPRSERKPLYVKVVTQPALHGCWAVNISETGIGLIATPHTPSEGPREGE
CEEEECCCHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCC
DVELSFSLPDSGEHIRVRGVVRWRHDASGAVAAMGVSFRAFEEADGVKLARYLASSHLQV
CEEEEEECCCCCCEEEEEEEEEEECCCCCCEEECCCCHHHHHHCCCHHHHHHHHHCCEEE
VVAFATEQESRAVTAALEGVAQLHFAASPSDAHALVTRGDAACLVVCGQDEEQALALVES
EEEEECCCHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHH
LAARRADADPSGAGPPSDLASRIVYCAPAAPERLVALFNDGRIFRALGPSPTREALHQAV
HHHHCCCCCCCCCCCHHHHHHHEEEECCCCHHHEEEEECCCEEEEECCCCHHHHHHHHHH
LQAGREHGVRTEQWRMALELERSLLRERALSQKLPPAPGGRGGDEVGFRSAAMQRVMELV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLVAPHRVAVLLQGETGTGKEVLARILHRLSGRGDVPLVVQDCGALSETLLESELFGHVK
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHC
GSFTGAVADHPGLFVLANGGTIFLDEIENTTANLQAKLLRVLETGDVRPVGGTQVRHVDV
CCCCEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
RVVAASNKDMGEEVRAGRFRADLFYRLNSFTVDIPPLRDRPEDVPELALYFLELFNRTLR
EEEEECCCCCHHHHHHCHHHHHHHEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
RSASGIAPDAVDALRAYAWPGNVRELRNVMERSVLLSRPGEVVSRRLLPPVLGSTLALRN
HHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCEEECC
EPGGDGSLRARLDRVEREFIREALERHGGVLRRAAVALGMDPVTLGRRVRRHGLWKGDS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]