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The map label for this gene is gpsA

Identifier: 108758245

GI number: 108758245

Start: 1589449

End: 1590456

Strand: Direct

Name: gpsA

Synonym: MXAN_1354

Alternate gene names: 108758245

Gene position: 1589449-1590456 (Clockwise)

Preceding gene: 108759140

Following gene: 108758489

Centisome position: 17.39

GC content: 68.25

Gene sequence:

>1008_bases
ATGCGTGGCAGTGTCATCGGCTCCGGCTCCTTCGGTACCGCCCTGGCGAACGTGCTCGCGGTCAATTGCGAGGAGGTTCG
TCTGTGGGGTCGTGAGTCCTCCGTGGTGGAGGCCATCAACACCCAGCACGAAAACCCCACCTACCTGAAGGGCATCCCCA
TCTCGGAGCGCGTGCGCGCCACGAATGACCTCCAGGAGGCGCTCGTGGGCTCGGAGTTGGTGGTGCTGGCCACGCCCAGC
CACGCCACGCGCGAGGTGGTGGCGAAGGCCCAGGCGTACCTGCCGCGCCATGTCCCCATCGTTACGGTGTCGAAGGGCAT
CGAGAACGGGACGCTGCTGACGATGACGGAGCTCCTGGAGGACTGCCTGCCGGAGGAGTTCCACCCGTACCTCGCGGTGC
TGTCCGGCCCCAGCTTCGCCAAGGAGCTGGCGCGGCGCATGCCCACGGTGGTGACCATCGCCTCCCACTGGGACAAGGTG
GCGCTGCGCTGCCAGAAGGCGCTGCAGACGGAGACGTTCCGCAGCTACACCTCCACGGACGTGGTGGGCGTGCAGTACGG
CGGCGCGCTGAAGAACGTCATCGCGATTGCCGCTGGCATGGCGGACGGCCTAGGCATGGGCCACAACGCGCGCGCGGCCA
TCATCACCCGCGGCCTGGCGGAGATTACGCGCCTGGCGGTGCGCAAGGGCGCCAACCCGCTGACGCTCTCCGGTCTGTCC
GGCATGGGCGACCTGGTGCTGACGTGCACCGGCGAGCTGAGCCGCAACCGGCACGTGGGGATGGAGCTGGGCAAGGGCCG
CAAGCTGCCGGACATCCTCGCGGACATGAAGGAAGTGGCCGAAGGTGTGAAGACGGCCCGCAGTGCGCACGAACTGGAGC
TCAAGACGGGCGTGGAGCTGCCCATCTGCCACCAGGTGTACCTGATTGCCCACGAGGGCAAGAGCGCGCGCACGGCGGTG
GTGGACCTGATGACGCGCCAGCCGAAGTCGGAGCTGGCGGGCGTCTGA

Upstream 100 bases:

>100_bases
CTCTGACGATTGGCGGGGACATCCGGACCCGGCCTGACGAGACGGATTTCATGCCCGTCATCACCTTTGGCGTCGTGACT
GGTTTCTAGCGAGGTCTTCC

Downstream 100 bases:

>100_bases
GCGGCCTTCAGTAGCGGCGCGGCGCGGCGTCCGGCGTGGCGCCGCGGACGCGCCACACGGTGAGCCGCTGGGAGTTGGTG
TGGCTCACCACCAGGCCCTC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRGSVIGSGSFGTALANVLAVNCEEVRLWGRESSVVEAINTQHENPTYLKGIPISERVRATNDLQEALVGSELVVLATPS
HATREVVAKAQAYLPRHVPIVTVSKGIENGTLLTMTELLEDCLPEEFHPYLAVLSGPSFAKELARRMPTVVTIASHWDKV
ALRCQKALQTETFRSYTSTDVVGVQYGGALKNVIAIAAGMADGLGMGHNARAAIITRGLAEITRLAVRKGANPLTLSGLS
GMGDLVLTCTGELSRNRHVGMELGKGRKLPDILADMKEVAEGVKTARSAHELELKTGVELPICHQVYLIAHEGKSARTAV
VDLMTRQPKSELAGV

Sequences:

>Translated_335_residues
MRGSVIGSGSFGTALANVLAVNCEEVRLWGRESSVVEAINTQHENPTYLKGIPISERVRATNDLQEALVGSELVVLATPS
HATREVVAKAQAYLPRHVPIVTVSKGIENGTLLTMTELLEDCLPEEFHPYLAVLSGPSFAKELARRMPTVVTIASHWDKV
ALRCQKALQTETFRSYTSTDVVGVQYGGALKNVIAIAAGMADGLGMGHNARAAIITRGLAEITRLAVRKGANPLTLSGLS
GMGDLVLTCTGELSRNRHVGMELGKGRKLPDILADMKEVAEGVKTARSAHELELKTGVELPICHQVYLIAHEGKSARTAV
VDLMTRQPKSELAGV
>Mature_335_residues
MRGSVIGSGSFGTALANVLAVNCEEVRLWGRESSVVEAINTQHENPTYLKGIPISERVRATNDLQEALVGSELVVLATPS
HATREVVAKAQAYLPRHVPIVTVSKGIENGTLLTMTELLEDCLPEEFHPYLAVLSGPSFAKELARRMPTVVTIASHWDKV
ALRCQKALQTETFRSYTSTDVVGVQYGGALKNVIAIAAGMADGLGMGHNARAAIITRGLAEITRLAVRKGANPLTLSGLS
GMGDLVLTCTGELSRNRHVGMELGKGRKLPDILADMKEVAEGVKTARSAHELELKTGVELPICHQVYLIAHEGKSARTAV
VDLMTRQPKSELAGV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=337, Percent_Identity=28.1899109792285, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI33695088, Length=330, Percent_Identity=27.2727272727273, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790037, Length=329, Percent_Identity=41.0334346504559, Blast_Score=248, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI32564399, Length=352, Percent_Identity=30.3977272727273, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=361, Percent_Identity=29.9168975069252, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=361, Percent_Identity=29.9168975069252, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=29.0140845070423, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=349, Percent_Identity=28.080229226361, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=30.635838150289, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=343, Percent_Identity=30.9037900874636, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136204, Length=273, Percent_Identity=28.9377289377289, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136202, Length=273, Percent_Identity=28.9377289377289, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136200, Length=272, Percent_Identity=29.0441176470588, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551945, Length=235, Percent_Identity=32.3404255319149, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281362270, Length=235, Percent_Identity=32.3404255319149, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24648969, Length=198, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22026922, Length=327, Percent_Identity=25.6880733944954, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_MYXXD (Q1DCL2)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629611.1
- ProteinModelPortal:   Q1DCL2
- SMR:   Q1DCL2
- STRING:   Q1DCL2
- GeneID:   4102105
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1354
- TIGR:   MXAN_1354
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q1DCL2
- ProtClustDB:   PRK00094
- BioCyc:   MXAN246197:MXAN_1354-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35859; Mature: 35859

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00957 NAD_G3PDH; PS00107 PROTEIN_KINASE_ATP

Important sites: ACT_SITE 191-191 BINDING 105-105 BINDING 105-105 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGSVIGSGSFGTALANVLAVNCEEVRLWGRESSVVEAINTQHENPTYLKGIPISERVRA
CCCCEECCCCHHHHHHHHHHCCHHHHEECCCCHHHHHHHHCCCCCCCEEECCCCHHHHHH
TNDLQEALVGSELVVLATPSHATREVVAKAQAYLPRHVPIVTVSKGIENGTLLTMTELLE
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHH
DCLPEEFHPYLAVLSGPSFAKELARRMPTVVTIASHWDKVALRCQKALQTETFRSYTSTD
HHCCHHCCCCEEEECCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
VVGVQYGGALKNVIAIAAGMADGLGMGHNARAAIITRGLAEITRLAVRKGANPLTLSGLS
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCC
GMGDLVLTCTGELSRNRHVGMELGKGRKLPDILADMKEVAEGVKTARSAHELELKTGVEL
CCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PICHQVYLIAHEGKSARTAVVDLMTRQPKSELAGV
CEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MRGSVIGSGSFGTALANVLAVNCEEVRLWGRESSVVEAINTQHENPTYLKGIPISERVRA
CCCCEECCCCHHHHHHHHHHCCHHHHEECCCCHHHHHHHHCCCCCCCEEECCCCHHHHHH
TNDLQEALVGSELVVLATPSHATREVVAKAQAYLPRHVPIVTVSKGIENGTLLTMTELLE
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHH
DCLPEEFHPYLAVLSGPSFAKELARRMPTVVTIASHWDKVALRCQKALQTETFRSYTSTD
HHCCHHCCCCEEEECCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
VVGVQYGGALKNVIAIAAGMADGLGMGHNARAAIITRGLAEITRLAVRKGANPLTLSGLS
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCC
GMGDLVLTCTGELSRNRHVGMELGKGRKLPDILADMKEVAEGVKTARSAHELELKTGVEL
CCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PICHQVYLIAHEGKSARTAVVDLMTRQPKSELAGV
CEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA