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The map label for this gene is tlpB [H]

Identifier: 108758139

GI number: 108758139

Start: 4471259

End: 4472818

Strand: Direct

Name: tlpB [H]

Synonym: MXAN_3754

Alternate gene names: 108758139

Gene position: 4471259-4472818 (Clockwise)

Preceding gene: 108762626

Following gene: 108760873

Centisome position: 48.92

GC content: 70.0

Gene sequence:

>1560_bases
ATGAACGTCTCGCTCGATGCCGACGTCCTCGCGAGACGTTCGCAATCCCTGTTCGACACCCACCAGGTGGCGCTGAGCCG
TCGCACGGACCGGATGTTCGCCGTGCTGATGGGGCTCCAGTGGGTTGGCGGGCTGGTGGTGGCCCTGGCGCTGTCCCCCC
GCACGTGGAGTGGGACGTCCAGTCAGGTCCATCCACACGTCTGGGCGGCGGCCGGCCTGGGAGCCCTCCTGGCGAGCCTG
CCGGTGGCCATGGCGTGGGCGTTGCCGGGTCGGGAGGTCACGCGCTTCGTCATCGCCACGGCGCAGGCATTGGTGTCCGG
GCTGCTCATCCATCTGACGGACGGGCGCATCGAGACGCACTTCCACATCTTCGGGTCCCTGGCGCTGCTGGCCATGTACC
GGGACGCGCGGGTGCTGTTCCTCTACTCGGCGCTGGTGGCGGTGGACCACCTGCTTCGCGGCCAGTACTGGCCCCTGTCC
ATCTTCGGCGTGGAGTCCGCCAGTGCCTGGCGCGCGTGGGAGCACATCGGCTGGGTGGTGTTCGAGAACGTGTTCCTCCT
GATTGGCGGGCGAGGCGCGGTGAAGGATGCCCGGGCGCTGGCGGCGCGACAGGCCTGGTTGGAGTTGTCTCAGGGAGAGG
TTCGCACGCGCGTGGTGGAGCCGCTGGTGGACTCGGCGCGGGCGCTGACGGAGGCGACCCATTCGCTCGTGTCGAGCACG
GATGACCAGCGCGCGATGCTGGCGCGCCAGTCCGCGGCGCTCACGGATACGCAGGTGGCGACGAACGAGATGCAGCGGGC
GTCTTCCACGGCCTCTCATCAGGCGGATGCCATCCTCGCCTCCACGCTCCAGGCGGGGGACGTGGGGGCTGACGCCGAGG
CCATGCTGGGCCAGAGCATGGAGGGCCTGGAGGCCATTCGCGCACAGGTGATGGAGATGGCCGGGCTCCTGCGTGGATTG
GACGGCCAGGCGCGGCAGCTCTCGAGCGTCACCCTGGCGGTGAAGGACCTGGCGGACCAGTCCCACATGGTGGCGGTGAA
CGCGGCCATCGAGGCGGCGCGCGCGGGAGTGCACGGCAAGGGCTTCGCGGTGGTGGCCACGGAGATGCGGCGGCTCGCGC
AGCAGTCCGTCCGGGCGGCGGGGCAGGTGAGCGGCATCCTGGACACCGCGCACCAGTCGATCCAGCACGTCGTGGAGCTC
TCCCTGGTGGGGGCGGAGCGGATGGCGCGGGACATCGAGGTGGTGCGCGCGTCGGGAGAGCGCCTGCGGGGGCTGTCCAC
CGTGCTGCGCACCAGCACGGAGGGCGTGCAGCAGATTTCAGTGGCGGTGGCGCGACAGGCCGCGGGCGTGGCGCGGATCT
CCGGCGCGGTGGATGAGCTGTCCGCGATGATGAAACAGACGCTGGGGCGTGTCGAACAGACGACCACCGCCGCCCAGACG
CTTCGCGTGGTGACGGGCCGTGTCCATGGCGTCATCGACACCTATCAAGGCACCAGGACGGATGAGGTGCCGCCAGCGAA
CGATGCGGGCCGGGTGATTGCGTTCAGACGGGACGCTTAA

Upstream 100 bases:

>100_bases
CATCATCGAAAAATTCTGTTCGGACTTACGTTTCGAGGTGGTGAGCGGGTAGGGTTGGGGTTGTTTTGACCCCGCTTGCT
GCCTCAACGGAAAGTGCCGG

Downstream 100 bases:

>100_bases
GCGGGCGTCCGCCGCGTGTGAGGTTGCCGGCCGGGGCGCGCGGTGTCGCCGCGCCCCGGAGCCCGCTCCTTCGCCTCAGT
GTCCGTCGAGCATGGACTCC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MNVSLDADVLARRSQSLFDTHQVALSRRTDRMFAVLMGLQWVGGLVVALALSPRTWSGTSSQVHPHVWAAAGLGALLASL
PVAMAWALPGREVTRFVIATAQALVSGLLIHLTDGRIETHFHIFGSLALLAMYRDARVLFLYSALVAVDHLLRGQYWPLS
IFGVESASAWRAWEHIGWVVFENVFLLIGGRGAVKDARALAARQAWLELSQGEVRTRVVEPLVDSARALTEATHSLVSST
DDQRAMLARQSAALTDTQVATNEMQRASSTASHQADAILASTLQAGDVGADAEAMLGQSMEGLEAIRAQVMEMAGLLRGL
DGQARQLSSVTLAVKDLADQSHMVAVNAAIEAARAGVHGKGFAVVATEMRRLAQQSVRAAGQVSGILDTAHQSIQHVVEL
SLVGAERMARDIEVVRASGERLRGLSTVLRTSTEGVQQISVAVARQAAGVARISGAVDELSAMMKQTLGRVEQTTTAAQT
LRVVTGRVHGVIDTYQGTRTDEVPPANDAGRVIAFRRDA

Sequences:

>Translated_519_residues
MNVSLDADVLARRSQSLFDTHQVALSRRTDRMFAVLMGLQWVGGLVVALALSPRTWSGTSSQVHPHVWAAAGLGALLASL
PVAMAWALPGREVTRFVIATAQALVSGLLIHLTDGRIETHFHIFGSLALLAMYRDARVLFLYSALVAVDHLLRGQYWPLS
IFGVESASAWRAWEHIGWVVFENVFLLIGGRGAVKDARALAARQAWLELSQGEVRTRVVEPLVDSARALTEATHSLVSST
DDQRAMLARQSAALTDTQVATNEMQRASSTASHQADAILASTLQAGDVGADAEAMLGQSMEGLEAIRAQVMEMAGLLRGL
DGQARQLSSVTLAVKDLADQSHMVAVNAAIEAARAGVHGKGFAVVATEMRRLAQQSVRAAGQVSGILDTAHQSIQHVVEL
SLVGAERMARDIEVVRASGERLRGLSTVLRTSTEGVQQISVAVARQAAGVARISGAVDELSAMMKQTLGRVEQTTTAAQT
LRVVTGRVHGVIDTYQGTRTDEVPPANDAGRVIAFRRDA
>Mature_519_residues
MNVSLDADVLARRSQSLFDTHQVALSRRTDRMFAVLMGLQWVGGLVVALALSPRTWSGTSSQVHPHVWAAAGLGALLASL
PVAMAWALPGREVTRFVIATAQALVSGLLIHLTDGRIETHFHIFGSLALLAMYRDARVLFLYSALVAVDHLLRGQYWPLS
IFGVESASAWRAWEHIGWVVFENVFLLIGGRGAVKDARALAARQAWLELSQGEVRTRVVEPLVDSARALTEATHSLVSST
DDQRAMLARQSAALTDTQVATNEMQRASSTASHQADAILASTLQAGDVGADAEAMLGQSMEGLEAIRAQVMEMAGLLRGL
DGQARQLSSVTLAVKDLADQSHMVAVNAAIEAARAGVHGKGFAVVATEMRRLAQQSVRAAGQVSGILDTAHQSIQHVVEL
SLVGAERMARDIEVVRASGERLRGLSTVLRTSTEGVQQISVAVARQAAGVARISGAVDELSAMMKQTLGRVEQTTTAAQT
LRVVTGRVHGVIDTYQGTRTDEVPPANDAGRVIAFRRDA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=192, Percent_Identity=28.6458333333333, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789453, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788194, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788195, Length=144, Percent_Identity=28.4722222222222, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI2367378, Length=151, Percent_Identity=27.8145695364238, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55470; Mature: 55470

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSLDADVLARRSQSLFDTHQVALSRRTDRMFAVLMGLQWVGGLVVALALSPRTWSGTS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
SQVHPHVWAAAGLGALLASLPVAMAWALPGREVTRFVIATAQALVSGLLIHLTDGRIETH
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEEEEECCCEEEH
FHIFGSLALLAMYRDARVLFLYSALVAVDHLLRGQYWPLSIFGVESASAWRAWEHIGWVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
FENVFLLIGGRGAVKDARALAARQAWLELSQGEVRTRVVEPLVDSARALTEATHSLVSST
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDQRAMLARQSAALTDTQVATNEMQRASSTASHQADAILASTLQAGDVGADAEAMLGQSM
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCH
EGLEAIRAQVMEMAGLLRGLDGQARQLSSVTLAVKDLADQSHMVAVNAAIEAARAGVHGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCC
GFAVVATEMRRLAQQSVRAAGQVSGILDTAHQSIQHVVELSLVGAERMARDIEVVRASGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RLRGLSTVLRTSTEGVQQISVAVARQAAGVARISGAVDELSAMMKQTLGRVEQTTTAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVVTGRVHGVIDTYQGTRTDEVPPANDAGRVIAFRRDA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MNVSLDADVLARRSQSLFDTHQVALSRRTDRMFAVLMGLQWVGGLVVALALSPRTWSGTS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
SQVHPHVWAAAGLGALLASLPVAMAWALPGREVTRFVIATAQALVSGLLIHLTDGRIETH
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEEEEECCCEEEH
FHIFGSLALLAMYRDARVLFLYSALVAVDHLLRGQYWPLSIFGVESASAWRAWEHIGWVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
FENVFLLIGGRGAVKDARALAARQAWLELSQGEVRTRVVEPLVDSARALTEATHSLVSST
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDQRAMLARQSAALTDTQVATNEMQRASSTASHQADAILASTLQAGDVGADAEAMLGQSM
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCH
EGLEAIRAQVMEMAGLLRGLDGQARQLSSVTLAVKDLADQSHMVAVNAAIEAARAGVHGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCC
GFAVVATEMRRLAQQSVRAAGQVSGILDTAHQSIQHVVELSLVGAERMARDIEVVRASGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RLRGLSTVLRTSTEGVQQISVAVARQAAGVARISGAVDELSAMMKQTLGRVEQTTTAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRVVTGRVHGVIDTYQGTRTDEVPPANDAGRVIAFRRDA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]