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The map label for this gene is gcvT [H]

Identifier: 108758135

GI number: 108758135

Start: 3566312

End: 3567400

Strand: Direct

Name: gcvT [H]

Synonym: MXAN_3040

Alternate gene names: 108758135

Gene position: 3566312-3567400 (Clockwise)

Preceding gene: 108761720

Following gene: 108761555

Centisome position: 39.02

GC content: 68.5

Gene sequence:

>1089_bases
ATGAAGATGGCCCGGCAAACGCCCCTCAACGCGGCACACCGCAAGCTGGGGGCCCGGATGGTCGACTTCGCTGGCTGGGA
CATGCCCGTCCAGTACAGCTCCGTCATCGGCGAGCATGAGGCCGTGCGCACCGGCGTCGGCCTGTTCGACGTCTCCCACA
TGGGCGAGGTGGAGTTCTCCGGTCCCGGCGCCCTGGACACGGTCAACGCGCTCATCTCCAACGACCTGGCCCGCGTCGCG
GACGGGCAGGCGGTGTATGCGGGCTTGCTCGACGAGCGAGGCACCTTCGTGGACGACGTGGTCGCCTACCGCTTCAGCCC
CGAGCGCATCTTCATCTGCGTCAACTCCAGCAACCGCGAGAAGGACGTCGCGTGGATGAAGGCGCACGCCAAGGGTGTGG
CACCCGTGGACCGGAGCGACGACTACGCGCAGATTGCCGTGCAGGGCCCCAAGGCCACCGGCCTGGTCCAGCGCCTGACG
AAGACGGACCTGTCGAAGATTGGCACCTACCGCTTCGCCGAGGGCGAGGTCGCCGGGGCGAAGTGCCTCATCTCCCGCAC
CGGCTACACCGGCGAGGACGGCTTCGAGCTGTACAGCGCGGCCGGGGACGCAGTGGCGCTGTGGGACGCGCTGCTCACCG
AGGGCCAGCAGGACGGCGTGAAGCCGTGTGGCCTGGGCGCCCGTGACAGCCTCCGCACGGAGATGAAGTACGCGCTCTAC
GGCAACGACATCGATGACCAGCACACCGCGCTGGAGGCCGGGCTGGGGTGGATCGTCAAGCTCGACAAGGCGGCCTTCAT
TGGCAAGGAAGCGCTGGTGGCGCAGAAGGCCGCGGGCGTGAAGCGCAAGCTGGTGGGCTTCGAGCTGACCGGCAGCGGCA
TTCCGCGCCACGGCTACGCCATCCTCAAGGACGGCGCGCCGGTGGGGGAGGTGACCAGCGGCACCATGGGCCCCACCGTG
AAGAAGGCCATTGGCATCGGCTACGTGCCCACCGAGCTGTCCACAGAGGGCTCCACCTTCGACGTGGACATCCGCGGCCG
CGCGGTGCCCGCAGTGGTGGTGAAGACCCCGTTCCACAAGAAGCCCTGA

Upstream 100 bases:

>100_bases
GAATCTTCATGTCGCCCCCAGTGTAGACGCTCCGCGTCGTCCTTGATCGGGCAAGTCTCGCGGCTATAGTCCGCGCCGTT
TTCCACACCCCTCCAGGAGA

Downstream 100 bases:

>100_bases
ATCATTCCCGTTCCAACCAGGAGCAACGACATGGCCGACAACATCCCCGGCGACCTGAAGTACACCCGTGAGCACGAGTG
GGCCCGCGTCCAGGGCACCT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKMARQTPLNAAHRKLGARMVDFAGWDMPVQYSSVIGEHEAVRTGVGLFDVSHMGEVEFSGPGALDTVNALISNDLARVA
DGQAVYAGLLDERGTFVDDVVAYRFSPERIFICVNSSNREKDVAWMKAHAKGVAPVDRSDDYAQIAVQGPKATGLVQRLT
KTDLSKIGTYRFAEGEVAGAKCLISRTGYTGEDGFELYSAAGDAVALWDALLTEGQQDGVKPCGLGARDSLRTEMKYALY
GNDIDDQHTALEAGLGWIVKLDKAAFIGKEALVAQKAAGVKRKLVGFELTGSGIPRHGYAILKDGAPVGEVTSGTMGPTV
KKAIGIGYVPTELSTEGSTFDVDIRGRAVPAVVVKTPFHKKP

Sequences:

>Translated_362_residues
MKMARQTPLNAAHRKLGARMVDFAGWDMPVQYSSVIGEHEAVRTGVGLFDVSHMGEVEFSGPGALDTVNALISNDLARVA
DGQAVYAGLLDERGTFVDDVVAYRFSPERIFICVNSSNREKDVAWMKAHAKGVAPVDRSDDYAQIAVQGPKATGLVQRLT
KTDLSKIGTYRFAEGEVAGAKCLISRTGYTGEDGFELYSAAGDAVALWDALLTEGQQDGVKPCGLGARDSLRTEMKYALY
GNDIDDQHTALEAGLGWIVKLDKAAFIGKEALVAQKAAGVKRKLVGFELTGSGIPRHGYAILKDGAPVGEVTSGTMGPTV
KKAIGIGYVPTELSTEGSTFDVDIRGRAVPAVVVKTPFHKKP
>Mature_362_residues
MKMARQTPLNAAHRKLGARMVDFAGWDMPVQYSSVIGEHEAVRTGVGLFDVSHMGEVEFSGPGALDTVNALISNDLARVA
DGQAVYAGLLDERGTFVDDVVAYRFSPERIFICVNSSNREKDVAWMKAHAKGVAPVDRSDDYAQIAVQGPKATGLVQRLT
KTDLSKIGTYRFAEGEVAGAKCLISRTGYTGEDGFELYSAAGDAVALWDALLTEGQQDGVKPCGLGARDSLRTEMKYALY
GNDIDDQHTALEAGLGWIVKLDKAAFIGKEALVAQKAAGVKRKLVGFELTGSGIPRHGYAILKDGAPVGEVTSGTMGPTV
KKAIGIGYVPTELSTEGSTFDVDIRGRAVPAVVVKTPFHKKP

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=367, Percent_Identity=35.9673024523161, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI257796258, Length=353, Percent_Identity=35.4107648725212, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI257796254, Length=359, Percent_Identity=34.8189415041783, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI24797151, Length=336, Percent_Identity=31.25, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI257796256, Length=312, Percent_Identity=33.974358974359, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI197927446, Length=341, Percent_Identity=28.1524926686217, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI21361378, Length=341, Percent_Identity=28.1524926686217, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI194306651, Length=317, Percent_Identity=28.391167192429, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1789272, Length=369, Percent_Identity=39.5663956639566, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17560118, Length=370, Percent_Identity=34.0540540540541, Blast_Score=190, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI32563613, Length=365, Percent_Identity=28.2191780821918, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994045, Length=374, Percent_Identity=25.1336898395722, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994052, Length=374, Percent_Identity=25.1336898395722, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320222, Length=381, Percent_Identity=32.0209973753281, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI20129441, Length=378, Percent_Identity=33.0687830687831, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI28571104, Length=320, Percent_Identity=29.0625, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20130091, Length=358, Percent_Identity=26.2569832402235, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 38608; Mature: 38608

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMARQTPLNAAHRKLGARMVDFAGWDMPVQYSSVIGEHEAVRTGVGLFDVSHMGEVEFS
CCCCCCCCHHHHHHHHCCEEEHHCCCCCCCHHHHHHCCHHHHHHCCCEEECCCCCCEEEC
GPGALDTVNALISNDLARVADGQAVYAGLLDERGTFVDDVVAYRFSPERIFICVNSSNRE
CCCHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHEEECCCEEEEEECCCCCC
KDVAWMKAHAKGVAPVDRSDDYAQIAVQGPKATGLVQRLTKTDLSKIGTYRFAEGEVAGA
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
KCLISRTGYTGEDGFELYSAAGDAVALWDALLTEGQQDGVKPCGLGARDSLRTEMKYALY
EEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEEEEEE
GNDIDDQHTALEAGLGWIVKLDKAAFIGKEALVAQKAAGVKRKLVGFELTGSGIPRHGYA
CCCCCHHHHHHHHCCCEEEEECCHHHHCHHHHHHHHHCCCHHHEEEEEEECCCCCCCCEE
ILKDGAPVGEVTSGTMGPTVKKAIGIGYVPTELSTEGSTFDVDIRGRAVPAVVVKTPFHK
EEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCC
KP
CC
>Mature Secondary Structure
MKMARQTPLNAAHRKLGARMVDFAGWDMPVQYSSVIGEHEAVRTGVGLFDVSHMGEVEFS
CCCCCCCCHHHHHHHHCCEEEHHCCCCCCCHHHHHHCCHHHHHHCCCEEECCCCCCEEEC
GPGALDTVNALISNDLARVADGQAVYAGLLDERGTFVDDVVAYRFSPERIFICVNSSNRE
CCCHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHEEECCCEEEEEECCCCCC
KDVAWMKAHAKGVAPVDRSDDYAQIAVQGPKATGLVQRLTKTDLSKIGTYRFAEGEVAGA
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
KCLISRTGYTGEDGFELYSAAGDAVALWDALLTEGQQDGVKPCGLGARDSLRTEMKYALY
EEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEEEEEE
GNDIDDQHTALEAGLGWIVKLDKAAFIGKEALVAQKAAGVKRKLVGFELTGSGIPRHGYA
CCCCCHHHHHHHHCCCEEEEECCHHHHCHHHHHHHHHCCCHHHEEEEEEECCCCCCCCEE
ILKDGAPVGEVTSGTMGPTVKKAIGIGYVPTELSTEGSTFDVDIRGRAVPAVVVKTPFHK
EEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCC
KP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA