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The map label for this gene is oprF [H]

Identifier: 108757918

GI number: 108757918

Start: 5215310

End: 5217172

Strand: Direct

Name: oprF [H]

Synonym: MXAN_4254

Alternate gene names: 108757918

Gene position: 5215310-5217172 (Clockwise)

Preceding gene: 108759035

Following gene: 108760052

Centisome position: 57.06

GC content: 69.83

Gene sequence:

>1863_bases
ATGACAACCTTCGCGGCTCCTCGGCGGGGCCCGTCCCAGCCTCGACCTTCCATGCGCCTTCCTCACTTCACACGGTCCTC
ACCGCGCAGCTTCCTTCGCCGCGTGACACGGCTCGCCGCCCCGTTGTTGCTGGTGGCTTCAGCCACCGCCAGCGCCCAAC
CCGCGGCGTCGCAGGCCATCGACGTGCAGCAGTACAAGCCGGCGCCGGGTGCCTATGACGTGCTCGGCATGCACGGCGCG
CGCATCGCGCCGCACCTTTCCTGGAACCTGGGCGCGTCGCTCAACTACGCGAATGATCCGCTCAACCTCGTGGACCCGCG
AGCGGACCGGTTCCTCTACCGCATCGTGGACAGCCAGCTCACGCTGGACCTGATGGGCGCCATCTCCCTGTTCGACCGGG
TGGAGCTTGGCGTCGCGCTGCCCATCTCCCACACGACGTCGGAACCCGCCGCCGCGGTGGCGCCGGACCTGTCGAACGGC
GTGGGGACCACGGGCGTGGGTGACCTGCGGCTGGTGCCGAAGGTCCGCCTGCTCTCCACCGACAGCGGGATCCACCTGGC
GGTGACGGCGCCCCTGACGTTGCCCACGGGCGGCGGCTCGAAGTTCCTGGGCTCGGACACGGTGACGTTCCAGCCGCGCT
TCGTGGCGGAGTGGGCCACCACCGCCGTCCGCCTGCTGGCCAACGTGGGCTTTAACGTCCGCCGCGAGGAGCAGTTGCGC
AACCTCCGCGTGGGCAACGAGTTCGCCTACGCGGTGGGCGCCGAGGTGCCCCTCACGCAGGCCCTCACGGCGCAAGCCAC
CCTGGCGGGCGCGCTGGGCCTGAAGGAGACGAGCGCCGAGGAGCGGCCCATGGAAGTCCTGGCCGCGCTGAAATACCGCT
TCACCCCGGGGTTGGCTGCGCATGTGGGCGCGGGCCCGGGCCTGTCGCGGGGCTATGGCACCCCGTCCTTCCGCGTGCTC
GCGGGTGTGGCCTGGACGCCGTTTGAATCCAAGGGCGGCCCCGCCTCCACCGCGCCGGTCTGCGACCTGGGGCCCGAGGA
CTTCGACGGCTTCCAGGACGACGACAACTGCCTGGACCCGGACGATGACGGTGACGGCATCCCCGACGTCACCGACGTGT
GCCCCACCGAGCCGGAGACCTTCAACAGCTTCCAGGACGAGGACGGTTGCCCGGATGACCCGAACGCCCACCAGCCACCC
ACCGAAGCGGGCCAGCCCGCACCGGCCCCGGCGCCCCTGGCGCTGCCGCCCGCGCCGGTGGATACCGACAAGGATGGCGT
TGTCGATTCGGAGGACCTGTGCCAGACCGAGCCGGAGGACTTGGACGGCTTCGAGGACGAGGACGGTTGCCCCGACCCCG
ACAACGACCAGGATGGCATCCCGGACGCCGAGGACCAGTGCCCGCTGGAGGCGGAGACCATCAACGGCGTGCAGGATGAT
GACGGCTGCCCGGACAAGGGCAAGGCGCAGGTGCGCGTGGAGGGCGCGCGCATCGTCATCCTGGACAAGGTGTACTTCGG
CACGGGCCAGGACGTGATTCTGGCCAGGTCCCACGGCCTGCTGCGGCAGGTGGCCGCCACGCTCAAGGCGAACCCGCGGA
TCCTGATGGTCCGTGTGGAAGGCCACACGGATGACCAGGGCAACGACATGAAGAACCTGGACCTGTCCCAGCGGCGGGCG
AGGAATGTGGTGGCCTTCCTGGTGAAGGAAGGCATCGCGGCGCAGCGGCTGGACGCGGTGGGCTATGGTGAAGCGAAGCC
GGTCGACACCAACGAGACGGCCAAGGGGCGCGAGAACAACCGGCGCGTCGAGTTCAACATCGTGAAGGTCGCCGAGCCTT
CGACGGGAGGAGGCACGCGTTGA

Upstream 100 bases:

>100_bases
GCTCCGCGCGACGATGCGTCATCGAGTTGCATTTCGCCGGGACGGCCCCGAACAACTGGGACACCGACGGCTCATCGTTT
CTTGAGTCAGTCATCCGCCG

Downstream 100 bases:

>100_bases
TGCGGACAGCCCCTTGGATGATGGCGGTGATGCTGGCGGGTCCACCCGCGCTCGCCGCGCAGACGCAGGCGCCGTGCGGC
GGGCTGCGCTTCGACAGCGG

Product: OmpA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTTFAAPRRGPSQPRPSMRLPHFTRSSPRSFLRRVTRLAAPLLLVASATASAQPAASQAIDVQQYKPAPGAYDVLGMHGA
RIAPHLSWNLGASLNYANDPLNLVDPRADRFLYRIVDSQLTLDLMGAISLFDRVELGVALPISHTTSEPAAAVAPDLSNG
VGTTGVGDLRLVPKVRLLSTDSGIHLAVTAPLTLPTGGGSKFLGSDTVTFQPRFVAEWATTAVRLLANVGFNVRREEQLR
NLRVGNEFAYAVGAEVPLTQALTAQATLAGALGLKETSAEERPMEVLAALKYRFTPGLAAHVGAGPGLSRGYGTPSFRVL
AGVAWTPFESKGGPASTAPVCDLGPEDFDGFQDDDNCLDPDDDGDGIPDVTDVCPTEPETFNSFQDEDGCPDDPNAHQPP
TEAGQPAPAPAPLALPPAPVDTDKDGVVDSEDLCQTEPEDLDGFEDEDGCPDPDNDQDGIPDAEDQCPLEAETINGVQDD
DGCPDKGKAQVRVEGARIVILDKVYFGTGQDVILARSHGLLRQVAATLKANPRILMVRVEGHTDDQGNDMKNLDLSQRRA
RNVVAFLVKEGIAAQRLDAVGYGEAKPVDTNETAKGRENNRRVEFNIVKVAEPSTGGGTR

Sequences:

>Translated_620_residues
MTTFAAPRRGPSQPRPSMRLPHFTRSSPRSFLRRVTRLAAPLLLVASATASAQPAASQAIDVQQYKPAPGAYDVLGMHGA
RIAPHLSWNLGASLNYANDPLNLVDPRADRFLYRIVDSQLTLDLMGAISLFDRVELGVALPISHTTSEPAAAVAPDLSNG
VGTTGVGDLRLVPKVRLLSTDSGIHLAVTAPLTLPTGGGSKFLGSDTVTFQPRFVAEWATTAVRLLANVGFNVRREEQLR
NLRVGNEFAYAVGAEVPLTQALTAQATLAGALGLKETSAEERPMEVLAALKYRFTPGLAAHVGAGPGLSRGYGTPSFRVL
AGVAWTPFESKGGPASTAPVCDLGPEDFDGFQDDDNCLDPDDDGDGIPDVTDVCPTEPETFNSFQDEDGCPDDPNAHQPP
TEAGQPAPAPAPLALPPAPVDTDKDGVVDSEDLCQTEPEDLDGFEDEDGCPDPDNDQDGIPDAEDQCPLEAETINGVQDD
DGCPDKGKAQVRVEGARIVILDKVYFGTGQDVILARSHGLLRQVAATLKANPRILMVRVEGHTDDQGNDMKNLDLSQRRA
RNVVAFLVKEGIAAQRLDAVGYGEAKPVDTNETAKGRENNRRVEFNIVKVAEPSTGGGTR
>Mature_619_residues
TTFAAPRRGPSQPRPSMRLPHFTRSSPRSFLRRVTRLAAPLLLVASATASAQPAASQAIDVQQYKPAPGAYDVLGMHGAR
IAPHLSWNLGASLNYANDPLNLVDPRADRFLYRIVDSQLTLDLMGAISLFDRVELGVALPISHTTSEPAAAVAPDLSNGV
GTTGVGDLRLVPKVRLLSTDSGIHLAVTAPLTLPTGGGSKFLGSDTVTFQPRFVAEWATTAVRLLANVGFNVRREEQLRN
LRVGNEFAYAVGAEVPLTQALTAQATLAGALGLKETSAEERPMEVLAALKYRFTPGLAAHVGAGPGLSRGYGTPSFRVLA
GVAWTPFESKGGPASTAPVCDLGPEDFDGFQDDDNCLDPDDDGDGIPDVTDVCPTEPETFNSFQDEDGCPDDPNAHQPPT
EAGQPAPAPAPLALPPAPVDTDKDGVVDSEDLCQTEPEDLDGFEDEDGCPDPDNDQDGIPDAEDQCPLEAETINGVQDDD
GCPDKGKAQVRVEGARIVILDKVYFGTGQDVILARSHGLLRQVAATLKANPRILMVRVEGHTDDQGNDMKNLDLSQRRAR
NVVAFLVKEGIAAQRLDAVGYGEAKPVDTNETAKGRENNRRVEFNIVKVAEPSTGGGTR

Specific function: Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium [H]

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=87, Percent_Identity=41.3793103448276, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 65893; Mature: 65762

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00018 EF_HAND_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFAAPRRGPSQPRPSMRLPHFTRSSPRSFLRRVTRLAAPLLLVASATASAQPAASQAI
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCC
DVQQYKPAPGAYDVLGMHGARIAPHLSWNLGASLNYANDPLNLVDPRADRFLYRIVDSQL
CHHHCCCCCCCCHHHCCCCCEECCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TLDLMGAISLFDRVELGVALPISHTTSEPAAAVAPDLSNGVGTTGVGDLRLVPKVRLLST
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCEEECCEEEEEEC
DSGIHLAVTAPLTLPTGGGSKFLGSDTVTFQPRFVAEWATTAVRLLANVGFNVRREEQLR
CCCEEEEEECCEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NLRVGNEFAYAVGAEVPLTQALTAQATLAGALGLKETSAEERPMEVLAALKYRFTPGLAA
HCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
HVGAGPGLSRGYGTPSFRVLAGVAWTPFESKGGPASTAPVCDLGPEDFDGFQDDDNCLDP
HCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DDDGDGIPDVTDVCPTEPETFNSFQDEDGCPDDPNAHQPPTEAGQPAPAPAPLALPPAPV
CCCCCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTDKDGVVDSEDLCQTEPEDLDGFEDEDGCPDPDNDQDGIPDAEDQCPLEAETINGVQDD
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
DGCPDKGKAQVRVEGARIVILDKVYFGTGQDVILARSHGLLRQVAATLKANPRILMVRVE
CCCCCCCCEEEEECCEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEC
GHTDDQGNDMKNLDLSQRRARNVVAFLVKEGIAAQRLDAVGYGEAKPVDTNETAKGRENN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RRVEFNIVKVAEPSTGGGTR
CEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TTFAAPRRGPSQPRPSMRLPHFTRSSPRSFLRRVTRLAAPLLLVASATASAQPAASQAI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCC
DVQQYKPAPGAYDVLGMHGARIAPHLSWNLGASLNYANDPLNLVDPRADRFLYRIVDSQL
CHHHCCCCCCCCHHHCCCCCEECCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TLDLMGAISLFDRVELGVALPISHTTSEPAAAVAPDLSNGVGTTGVGDLRLVPKVRLLST
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCEEECCEEEEEEC
DSGIHLAVTAPLTLPTGGGSKFLGSDTVTFQPRFVAEWATTAVRLLANVGFNVRREEQLR
CCCEEEEEECCEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
NLRVGNEFAYAVGAEVPLTQALTAQATLAGALGLKETSAEERPMEVLAALKYRFTPGLAA
HCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
HVGAGPGLSRGYGTPSFRVLAGVAWTPFESKGGPASTAPVCDLGPEDFDGFQDDDNCLDP
HCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DDDGDGIPDVTDVCPTEPETFNSFQDEDGCPDDPNAHQPPTEAGQPAPAPAPLALPPAPV
CCCCCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTDKDGVVDSEDLCQTEPEDLDGFEDEDGCPDPDNDQDGIPDAEDQCPLEAETINGVQDD
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
DGCPDKGKAQVRVEGARIVILDKVYFGTGQDVILARSHGLLRQVAATLKANPRILMVRVE
CCCCCCCCEEEEECCEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEC
GHTDDQGNDMKNLDLSQRRARNVVAFLVKEGIAAQRLDAVGYGEAKPVDTNETAKGRENN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RRVEFNIVKVAEPSTGGGTR
CEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1898935 [H]