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The map label for this gene is dac [H]

Identifier: 108757859

GI number: 108757859

Start: 3667628

End: 3669112

Strand: Reverse

Name: dac [H]

Synonym: MXAN_3130

Alternate gene names: 108757859

Gene position: 3669112-3667628 (Counterclockwise)

Preceding gene: 108760487

Following gene: 108758082

Centisome position: 40.14

GC content: 73.54

Gene sequence:

>1485_bases
ATGCGCCGCATCCTGTCCGCCTCGCTGCTGCTCGTGGCCCCCCTGGTCCTCTCCGGCTGCTTCCGCGAGACGCGCCCCGA
GGGCGACACCCTTCCCTCCCTGGCCCGCGCGCTCTTCGAAACCCTGGAGGCCGAAGGCGCCCTGGCCAGCGCCTACGTGG
TGGACGCGCAGACGGGCGAGCCACTCTTCACCCACCGCGAGCATGTCCGGCTCCTGCCCGCCTCCACGCTCAAGGTCGTC
TCCACCGCGTCGGTCCTCTCCGCGCTGGGCGCGGACTTCCGCTTCCAGACGCCGGTGGCCCTGGAGGGCACGCTGGATGG
CGGGCTCTTCCTGGGTGACATCGTGGTGGAGCCCACGGGGGACCCGTCCCTGGGCTCGTGGCGCTTCCCCGAGACGGCGC
TGGCGTGTGAGCAGGTGGCGGACGCCCTCCAGGCGCGCGGCATCCGCCAGTGGCGCGGGCAGGTGCGCGTGCGCGGCGCG
AAGGAGGCGGAGTTCCCGTTCGGCCCTGGCTGGGCCTGGGATGACGCCGCCTATGCCTACAGCGCGGCGCCAACGGCCTT
CGTCTTCCGGGAGAACGTGGTGGACGTGGCGCTGTCCCGGGCGGCGGGCGCGGCCTGCGCGCAGCCCCCCACCATCCAGG
TGACCCCCACCTTCGCGACGCTGCCGGCCGTGGTGGGTGTGGACACGAACGCGGAGCGCCCCTCCCTGGCCTGCGTGCGC
CAGCGTGGCGGCCCCGGCGTGCGCTGCCTGTGGCGCTCCACCGCGGACACCTGCCCCCGCTCCGCCGCGGTGAGGCTGTC
GGTGGACGAGCCCGAGCAGCTCTTCTCCGCCTGTGTGGAGGCCGCCCTGCTCGCGCGCGGCATCCCTCGGCTGCCCATGA
CGCTGGAGGCGCCCACGCCGCGGCAACCCGCGGTGCCCGCACCCCTGGTCACCCTGGTCAGCCCGCCGCTGTCCGAGTTG
GTGAAGGTGACGAACAAGGAATCCCTCAACCTGTACGCGGAGCGCCTGGGCCTGCGCTTCGCGCGCGAGCTCACCGGCAC
GGAGAGCTATGGCGCCCTCCGCACCGCGCTGACGGAGGAACTGACCCGCCGAGGCATCCCCTCGCGAGACTTGCGCCCGG
TGGATGGCAGTGGCCTGTCCCGGTACAACCTGGCCACCGCGCGGGGACTGGTGCGCGTCATCTTCACCAGCCTGCGTGAA
GCCTACGGCACCGCGCTGCTGGACAGCCTGCCCGTGGCCGGCCTGGACGGCACGCTCGCGGCCCGCCCCGTCACCGCCGA
CACCGCGGGCCACATCCGCGCGAAGACGGGCACGCTGTCCGGTCAGCGGTGCTTCGTGGGGGTAGTGGACCGGCCGGGAG
ACGCGCGGCACCCACGCGTCGTCTTCGCGCTGATGCTGGGGAACATGGACGACGGCACCGCTCTGCCCGCCAATGAGGCG
TTCGACCGGTTCACCGCGGGGCTGGTCACACTGCCGCTGCGCTGA

Upstream 100 bases:

>100_bases
GTGGCTGGCGGCGCCTTCCTCGTGGCCGCGCTCCCTTTCCAGGCGGCCAGTCCCCGGCCGAATGACAGGGCCGCCCCACG
GCGGTAGCGTGGCGGGCGAC

Downstream 100 bases:

>100_bases
CGGCCAGGACGCACCGTCTCATTCCCAACGGTTGCACGGCGGAAGCGCGGGCGAACACCCGGCGCACGGCGGCATTCCCG
ACGCAACGAAGCCGTTTCCC

Product: putative D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein; PBP [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MRRILSASLLLVAPLVLSGCFRETRPEGDTLPSLARALFETLEAEGALASAYVVDAQTGEPLFTHREHVRLLPASTLKVV
STASVLSALGADFRFQTPVALEGTLDGGLFLGDIVVEPTGDPSLGSWRFPETALACEQVADALQARGIRQWRGQVRVRGA
KEAEFPFGPGWAWDDAAYAYSAAPTAFVFRENVVDVALSRAAGAACAQPPTIQVTPTFATLPAVVGVDTNAERPSLACVR
QRGGPGVRCLWRSTADTCPRSAAVRLSVDEPEQLFSACVEAALLARGIPRLPMTLEAPTPRQPAVPAPLVTLVSPPLSEL
VKVTNKESLNLYAERLGLRFARELTGTESYGALRTALTEELTRRGIPSRDLRPVDGSGLSRYNLATARGLVRVIFTSLRE
AYGTALLDSLPVAGLDGTLAARPVTADTAGHIRAKTGTLSGQRCFVGVVDRPGDARHPRVVFALMLGNMDDGTALPANEA
FDRFTAGLVTLPLR

Sequences:

>Translated_494_residues
MRRILSASLLLVAPLVLSGCFRETRPEGDTLPSLARALFETLEAEGALASAYVVDAQTGEPLFTHREHVRLLPASTLKVV
STASVLSALGADFRFQTPVALEGTLDGGLFLGDIVVEPTGDPSLGSWRFPETALACEQVADALQARGIRQWRGQVRVRGA
KEAEFPFGPGWAWDDAAYAYSAAPTAFVFRENVVDVALSRAAGAACAQPPTIQVTPTFATLPAVVGVDTNAERPSLACVR
QRGGPGVRCLWRSTADTCPRSAAVRLSVDEPEQLFSACVEAALLARGIPRLPMTLEAPTPRQPAVPAPLVTLVSPPLSEL
VKVTNKESLNLYAERLGLRFARELTGTESYGALRTALTEELTRRGIPSRDLRPVDGSGLSRYNLATARGLVRVIFTSLRE
AYGTALLDSLPVAGLDGTLAARPVTADTAGHIRAKTGTLSGQRCFVGVVDRPGDARHPRVVFALMLGNMDDGTALPANEA
FDRFTAGLVTLPLR
>Mature_494_residues
MRRILSASLLLVAPLVLSGCFRETRPEGDTLPSLARALFETLEAEGALASAYVVDAQTGEPLFTHREHVRLLPASTLKVV
STASVLSALGADFRFQTPVALEGTLDGGLFLGDIVVEPTGDPSLGSWRFPETALACEQVADALQARGIRQWRGQVRVRGA
KEAEFPFGPGWAWDDAAYAYSAAPTAFVFRENVVDVALSRAAGAACAQPPTIQVTPTFATLPAVVGVDTNAERPSLACVR
QRGGPGVRCLWRSTADTCPRSAAVRLSVDEPEQLFSACVEAALLARGIPRLPMTLEAPTPRQPAVPAPLVTLVSPPLSEL
VKVTNKESLNLYAERLGLRFARELTGTESYGALRTALTEELTRRGIPSRDLRPVDGSGLSRYNLATARGLVRVIFTSLRE
AYGTALLDSLPVAGLDGTLAARPVTADTAGHIRAKTGTLSGQRCFVGVVDRPGDARHPRVVFALMLGNMDDGTALPANEA
FDRFTAGLVTLPLR

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=404, Percent_Identity=26.7326732673267, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 52598; Mature: 52598

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILSASLLLVAPLVLSGCFRETRPEGDTLPSLARALFETLEAEGALASAYVVDAQTGE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PLFTHREHVRLLPASTLKVVSTASVLSALGADFRFQTPVALEGTLDGGLFLGDIVVEPTG
CCHHCCHHHEECCCHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCEEEEEEEEECCC
DPSLGSWRFPETALACEQVADALQARGIRQWRGQVRVRGAKEAEFPFGPGWAWDDAAYAY
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCC
SAAPTAFVFRENVVDVALSRAAGAACAQPPTIQVTPTFATLPAVVGVDTNAERPSLACVR
CCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHEECCCCCCCCHHHHHH
QRGGPGVRCLWRSTADTCPRSAAVRLSVDEPEQLFSACVEAALLARGIPRLPMTLEAPTP
HCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
RQPAVPAPLVTLVSPPLSELVKVTNKESLNLYAERLGLRFARELTGTESYGALRTALTEE
CCCCCCCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LTRRGIPSRDLRPVDGSGLSRYNLATARGLVRVIFTSLREAYGTALLDSLPVAGLDGTLA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ARPVTADTAGHIRAKTGTLSGQRCFVGVVDRPGDARHPRVVFALMLGNMDDGTALPANEA
CCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
FDRFTAGLVTLPLR
HHHHHCCEEEECCC
>Mature Secondary Structure
MRRILSASLLLVAPLVLSGCFRETRPEGDTLPSLARALFETLEAEGALASAYVVDAQTGE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PLFTHREHVRLLPASTLKVVSTASVLSALGADFRFQTPVALEGTLDGGLFLGDIVVEPTG
CCHHCCHHHEECCCHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCEEEEEEEEECCC
DPSLGSWRFPETALACEQVADALQARGIRQWRGQVRVRGAKEAEFPFGPGWAWDDAAYAY
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCC
SAAPTAFVFRENVVDVALSRAAGAACAQPPTIQVTPTFATLPAVVGVDTNAERPSLACVR
CCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHEECCCCCCCCHHHHHH
QRGGPGVRCLWRSTADTCPRSAAVRLSVDEPEQLFSACVEAALLARGIPRLPMTLEAPTP
HCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
RQPAVPAPLVTLVSPPLSELVKVTNKESLNLYAERLGLRFARELTGTESYGALRTALTEE
CCCCCCCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LTRRGIPSRDLRPVDGSGLSRYNLATARGLVRVIFTSLREAYGTALLDSLPVAGLDGTLA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ARPVTADTAGHIRAKTGTLSGQRCFVGVVDRPGDARHPRVVFALMLGNMDDGTALPANEA
CCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
FDRFTAGLVTLPLR
HHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1554361; 7305936 [H]