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The map label for this gene is mocR [H]

Identifier: 108757615

GI number: 108757615

Start: 639479

End: 640906

Strand: Reverse

Name: mocR [H]

Synonym: MXAN_0556

Alternate gene names: 108757615

Gene position: 640906-639479 (Counterclockwise)

Preceding gene: 108758605

Following gene: 108761638

Centisome position: 7.01

GC content: 71.36

Gene sequence:

>1428_bases
ATGGACCTTCACGTCGACCTCCAGGACCGCAGAGACGTCGCGGGGCAAATCTACCGAGGGTTGCGCGCGAGGATTCTCGA
CGGGCGGCTGCGAGACGGTGAGCAGGTTCCTCCATCGCGTGAGCTGGCCCAGCGGCTGGGCGTCTCGCGCAACACGGTGG
GCGTAGCCTACGAATGGCTGACCGCCGAGGGCCTGCTCGTGGGCCGAGGCCGCGCGGGGAGCTTCGTCCAGAACGCGCCC
CGGGAACGAGGTGCGCGCGCGGCGGCAACGCGCGGTGTGAAGCTGCGTCCGCGCGCCGTCTGGAGCGAGCTGCACGTCCC
ACCACCCGCCGAGCCGCCAGCGCCGTATGACTTCCGCGTCGGCAACCCCGACGCCGCGTTGTTCCCGTTCGAAGCCTGGC
ATCGGCTGCTCGCGCGGCACCTGCGCGCCGCCGCGATGACGGCAGCCTACGCGGACCCGGCCGGCCACCCCGAGCTGCGC
GAGGCCGTGGCACGCCACGTGGGCGTCTCCCGAGGCGTTCGTGCCGAAGCGTCGGACGTGCTCATCACACATGGAGCGCA
GCAGGCGCTGGACCTCGCGGGCCGGGTGCTGCTGGAGCCCGGAGACCGCGTCGCCGTGGAGGAACCCGGCTACCCACCCG
CACGGCTCCTGTTCCAGTCACTCGGAGCCCACGTGGTGCCGGTGCCAGTCGACAAGGAGGGGCTTGACGTGCAGGCACTG
CCGGATGACACGCGCCTCGTCTACGTCACGCCGTCCCACCAGTTCCCGCTGGGCATCGTGATGTCGCCCGCGCGCCGCAG
GGCCCTGCTCGACTGGGCACGGCGGCGCGACGCAGTGGTCATCGAGGACGACTACGACAGCGAGTTCCGCTTCGGCGGCC
GGCCCTTGGAGACGTTGCACAGCCTGGATCGTTCGGGTCGCGTCCTCTACGTGGGCTCGTTCTCCAAGGTGCTGCTCCCC
GCGCTGCGACTGGGATTCCTCGTCGCGCCGCCCTCGCTCCAACGAGAGCTCCGGCTGGCGAAGCAGGTGACGGACTGGCA
CAGCCAGCTTCCCGCGCAGGCGGCGCTCGCGCGCTTCATCGACACGGGAGCACTGGCCCGGCACCTGCGAAAGACGCGGC
GCGAGTACGAGCAACGGCACACGCGGCTGTCGGAGAAGCTCCGCCACCACTTTGGAGACGCCCTTGAGCAACTGCCCTCC
GTCGCCGGACTGCATCTGTGCGTCACCTTCACGCGGGGCGGCGCTCGGTTGGAGCGGGAGCTCACGCGGCGAGCCCGTGA
CGCGGGCATCGGCATCGAAGCGCTCTCCGGCTACTTCGCCGGGGCGCCCACCCGCCATGGCTGGGTGCTGGGCTACGGCG
GCGTGACGGTGGACCGCATCGACGAGGGACTCTGGCGCCTGCGAACGCGCCTCGCCGGAGCCCTCTGA

Upstream 100 bases:

>100_bases
AGGACGTGTCGTTCATGCCCGTCAGATTGCGCTCTCACTGGCCCTCCCACCGGGCCAGAATTGACGAATCTCACTGGGCC
AAACTAGAGGGGCGTCTGGC

Downstream 100 bases:

>100_bases
GGCCACCGCACACTGCCCTCCCGTCAGTCCCGAAGCACCGCCCCCGTCCGCGCCCGCGACTCAAGCCTGAACCGGAACGG
AAACCGCCATGTTCTCCTCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MDLHVDLQDRRDVAGQIYRGLRARILDGRLRDGEQVPPSRELAQRLGVSRNTVGVAYEWLTAEGLLVGRGRAGSFVQNAP
RERGARAAATRGVKLRPRAVWSELHVPPPAEPPAPYDFRVGNPDAALFPFEAWHRLLARHLRAAAMTAAYADPAGHPELR
EAVARHVGVSRGVRAEASDVLITHGAQQALDLAGRVLLEPGDRVAVEEPGYPPARLLFQSLGAHVVPVPVDKEGLDVQAL
PDDTRLVYVTPSHQFPLGIVMSPARRRALLDWARRRDAVVIEDDYDSEFRFGGRPLETLHSLDRSGRVLYVGSFSKVLLP
ALRLGFLVAPPSLQRELRLAKQVTDWHSQLPAQAALARFIDTGALARHLRKTRREYEQRHTRLSEKLRHHFGDALEQLPS
VAGLHLCVTFTRGGARLERELTRRARDAGIGIEALSGYFAGAPTRHGWVLGYGGVTVDRIDEGLWRLRTRLAGAL

Sequences:

>Translated_475_residues
MDLHVDLQDRRDVAGQIYRGLRARILDGRLRDGEQVPPSRELAQRLGVSRNTVGVAYEWLTAEGLLVGRGRAGSFVQNAP
RERGARAAATRGVKLRPRAVWSELHVPPPAEPPAPYDFRVGNPDAALFPFEAWHRLLARHLRAAAMTAAYADPAGHPELR
EAVARHVGVSRGVRAEASDVLITHGAQQALDLAGRVLLEPGDRVAVEEPGYPPARLLFQSLGAHVVPVPVDKEGLDVQAL
PDDTRLVYVTPSHQFPLGIVMSPARRRALLDWARRRDAVVIEDDYDSEFRFGGRPLETLHSLDRSGRVLYVGSFSKVLLP
ALRLGFLVAPPSLQRELRLAKQVTDWHSQLPAQAALARFIDTGALARHLRKTRREYEQRHTRLSEKLRHHFGDALEQLPS
VAGLHLCVTFTRGGARLERELTRRARDAGIGIEALSGYFAGAPTRHGWVLGYGGVTVDRIDEGLWRLRTRLAGAL
>Mature_475_residues
MDLHVDLQDRRDVAGQIYRGLRARILDGRLRDGEQVPPSRELAQRLGVSRNTVGVAYEWLTAEGLLVGRGRAGSFVQNAP
RERGARAAATRGVKLRPRAVWSELHVPPPAEPPAPYDFRVGNPDAALFPFEAWHRLLARHLRAAAMTAAYADPAGHPELR
EAVARHVGVSRGVRAEASDVLITHGAQQALDLAGRVLLEPGDRVAVEEPGYPPARLLFQSLGAHVVPVPVDKEGLDVQAL
PDDTRLVYVTPSHQFPLGIVMSPARRRALLDWARRRDAVVIEDDYDSEFRFGGRPLETLHSLDRSGRVLYVGSFSKVLLP
ALRLGFLVAPPSLQRELRLAKQVTDWHSQLPAQAALARFIDTGALARHLRKTRREYEQRHTRLSEKLRHHFGDALEQLPS
VAGLHLCVTFTRGGARLERELTRRARDAGIGIEALSGYFAGAPTRHGWVLGYGGVTVDRIDEGLWRLRTRLAGAL

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=354, Percent_Identity=24.8587570621469, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI33469970, Length=354, Percent_Identity=24.8587570621469, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI1790797, Length=414, Percent_Identity=31.6425120772947, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787710, Length=441, Percent_Identity=29.4784580498866, Blast_Score=148, Evalue=9e-37,
Organism=Drosophila melanogaster, GI21356535, Length=243, Percent_Identity=26.7489711934156, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52578; Mature: 52578

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHVDLQDRRDVAGQIYRGLRARILDGRLRDGEQVPPSRELAQRLGVSRNTVGVAYEWL
CCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEEEEE
TAEGLLVGRGRAGSFVQNAPRERGARAAATRGVKLRPRAVWSELHVPPPAEPPAPYDFRV
EECCEEEECCCCCCHHHCCCHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEC
GNPDAALFPFEAWHRLLARHLRAAAMTAAYADPAGHPELREAVARHVGVSRGVRAEASDV
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LITHGAQQALDLAGRVLLEPGDRVAVEEPGYPPARLLFQSLGAHVVPVPVDKEGLDVQAL
EEECCHHHHHHHHCCEEECCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCEEEC
PDDTRLVYVTPSHQFPLGIVMSPARRRALLDWARRRDAVVIEDDYDSEFRFGGRPLETLH
CCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHH
SLDRSGRVLYVGSFSKVLLPALRLGFLVAPPSLQRELRLAKQVTDWHSQLPAQAALARFI
HHCCCCCEEEECCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DTGALARHLRKTRREYEQRHTRLSEKLRHHFGDALEQLPSVAGLHLCVTFTRGGARLERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHH
LTRRARDAGIGIEALSGYFAGAPTRHGWVLGYGGVTVDRIDEGLWRLRTRLAGAL
HHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLHVDLQDRRDVAGQIYRGLRARILDGRLRDGEQVPPSRELAQRLGVSRNTVGVAYEWL
CCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEEEEE
TAEGLLVGRGRAGSFVQNAPRERGARAAATRGVKLRPRAVWSELHVPPPAEPPAPYDFRV
EECCEEEECCCCCCHHHCCCHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEEC
GNPDAALFPFEAWHRLLARHLRAAAMTAAYADPAGHPELREAVARHVGVSRGVRAEASDV
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LITHGAQQALDLAGRVLLEPGDRVAVEEPGYPPARLLFQSLGAHVVPVPVDKEGLDVQAL
EEECCHHHHHHHHCCEEECCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCEEEC
PDDTRLVYVTPSHQFPLGIVMSPARRRALLDWARRRDAVVIEDDYDSEFRFGGRPLETLH
CCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHH
SLDRSGRVLYVGSFSKVLLPALRLGFLVAPPSLQRELRLAKQVTDWHSQLPAQAALARFI
HHCCCCCEEEECCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DTGALARHLRKTRREYEQRHTRLSEKLRHHFGDALEQLPSVAGLHLCVTFTRGGARLERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHH
LTRRARDAGIGIEALSGYFAGAPTRHGWVLGYGGVTVDRIDEGLWRLRTRLAGAL
HHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]