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The map label for this gene is plsC [H]

Identifier: 108757493

GI number: 108757493

Start: 4832727

End: 4833518

Strand: Reverse

Name: plsC [H]

Synonym: MXAN_3969

Alternate gene names: 108757493

Gene position: 4833518-4832727 (Counterclockwise)

Preceding gene: 108762443

Following gene: 108759720

Centisome position: 52.88

GC content: 68.81

Gene sequence:

>792_bases
TTGTTCGAGGCTCTCATGAACGCACTGCTCTCCATCTGGACGTGGATCGAGATTGGCCTGGTGGCGCTGGTCGGCTTCTG
TGTGCAGCTGTCGCTGGCCATCCTGACCTGGGCCTTCGACCACAAGCGCCACGTGACGGGACGCTGCTTCCGGCTCATCG
GCGTCACCGCGGCGAAGCTGACGCCGTTCTGGCGCTTCGGCGTGCACGGCCAGGTGCCGGACAAGGTCGCGCCGAACACG
GTGGTCGTAAGCAACCACGAGTCCAACGCGGACCCGTTCCTCATCTCGCACCTGCCGTGGGAGATGAAGTGGCTGGGCAA
GGCCAGCCTCTTCAAGATTCCCGTGGTGGGCTGGAGCATGTGGATGGCGGGGGACGTCCCCGTGCACCGCGGCGACCGCG
ACTCGGCGACGGGCGCCATGGCGAAGTGCCGCCAGTGGCTGGCCAAGGGCATGCCGGTGATGATCTTCCCGGAAGGGACG
CGCTCGAAGACGGATGACCTGCTGCCCTTCAAGGACGGCGCGTTCCGGCTGGCCATCGAGGCGCAGGCGGACGTGCTGCC
CCTGGCGGTGAGCGGGACGCGGCGGGCGCTGCCGAAGCACTCCTGGCGCTTCGCCACCTCGCGCGGTTTGGTGACGGTGG
GCACGCCCATCTCCACCAAGGGGATGACGCTGGCGGACGTGGAGACGCTGAAGAACCTGGCCCGCGAGCAGATCCTGTCA
CTGCGGGCTTCGCTGATGCCGCTGACGCGCACCGAGCCGGCCGTGCCGCCGGGGCCGGCCAGCGCCGCGTGA

Upstream 100 bases:

>100_bases
GGCCATGGCCTACGTGCGCAAGGCTGGCATCCACCCGGACGTGCTCGGCTCGGACCACTGTCCGGTGAGCGTGGACCTGG
ACCCCGCGGTTCGCTGACGC

Downstream 100 bases:

>100_bases
CTCAGACGTCCTTGTCGCTCTCGTCGACGATGTGGCAGCCAGTCTCCTCGTCGAGCGCGTCTTCAATGAAGCCGCGCACG
ATGTCCCGGCCGCCAATCTC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFEALMNALLSIWTWIEIGLVALVGFCVQLSLAILTWAFDHKRHVTGRCFRLIGVTAAKLTPFWRFGVHGQVPDKVAPNT
VVVSNHESNADPFLISHLPWEMKWLGKASLFKIPVVGWSMWMAGDVPVHRGDRDSATGAMAKCRQWLAKGMPVMIFPEGT
RSKTDDLLPFKDGAFRLAIEAQADVLPLAVSGTRRALPKHSWRFATSRGLVTVGTPISTKGMTLADVETLKNLAREQILS
LRASLMPLTRTEPAVPPGPASAA

Sequences:

>Translated_263_residues
MFEALMNALLSIWTWIEIGLVALVGFCVQLSLAILTWAFDHKRHVTGRCFRLIGVTAAKLTPFWRFGVHGQVPDKVAPNT
VVVSNHESNADPFLISHLPWEMKWLGKASLFKIPVVGWSMWMAGDVPVHRGDRDSATGAMAKCRQWLAKGMPVMIFPEGT
RSKTDDLLPFKDGAFRLAIEAQADVLPLAVSGTRRALPKHSWRFATSRGLVTVGTPISTKGMTLADVETLKNLAREQILS
LRASLMPLTRTEPAVPPGPASAA
>Mature_263_residues
MFEALMNALLSIWTWIEIGLVALVGFCVQLSLAILTWAFDHKRHVTGRCFRLIGVTAAKLTPFWRFGVHGQVPDKVAPNT
VVVSNHESNADPFLISHLPWEMKWLGKASLFKIPVVGWSMWMAGDVPVHRGDRDSATGAMAKCRQWLAKGMPVMIFPEGT
RSKTDDLLPFKDGAFRLAIEAQADVLPLAVSGTRRALPKHSWRFATSRGLVTVGTPISTKGMTLADVETLKNLAREQILS
LRASLMPLTRTEPAVPPGPASAA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=163, Percent_Identity=33.7423312883436, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI15100175, Length=163, Percent_Identity=33.7423312883436, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI6041665, Length=194, Percent_Identity=30.4123711340206, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789395, Length=144, Percent_Identity=31.9444444444444, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=177, Percent_Identity=28.2485875706215, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=199, Percent_Identity=29.6482412060301, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641614, Length=164, Percent_Identity=30.4878048780488, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641612, Length=164, Percent_Identity=30.4878048780488, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364648, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582856, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582854, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28846; Mature: 28846

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEALMNALLSIWTWIEIGLVALVGFCVQLSLAILTWAFDHKRHVTGRCFRLIGVTAAKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TPFWRFGVHGQVPDKVAPNTVVVSNHESNADPFLISHLPWEMKWLGKASLFKIPVVGWSM
CCHHEECCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCEEEEEEECCHH
WMAGDVPVHRGDRDSATGAMAKCRQWLAKGMPVMIFPEGTRSKTDDLLPFKDGAFRLAIE
EEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
AQADVLPLAVSGTRRALPKHSWRFATSRGLVTVGTPISTKGMTLADVETLKNLAREQILS
CCCCEEEEEECCCHHCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LRASLMPLTRTEPAVPPGPASAA
HHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFEALMNALLSIWTWIEIGLVALVGFCVQLSLAILTWAFDHKRHVTGRCFRLIGVTAAKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TPFWRFGVHGQVPDKVAPNTVVVSNHESNADPFLISHLPWEMKWLGKASLFKIPVVGWSM
CCHHEECCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCEEEEEEECCHH
WMAGDVPVHRGDRDSATGAMAKCRQWLAKGMPVMIFPEGTRSKTDDLLPFKDGAFRLAIE
EEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
AQADVLPLAVSGTRRALPKHSWRFATSRGLVTVGTPISTKGMTLADVETLKNLAREQILS
CCCCEEEEEECCCHHCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LRASLMPLTRTEPAVPPGPASAA
HHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]