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The map label for this gene is argD [H]

Identifier: 108757298

GI number: 108757298

Start: 3540473

End: 3541717

Strand: Direct

Name: argD [H]

Synonym: MXAN_3014

Alternate gene names: 108757298

Gene position: 3540473-3541717 (Clockwise)

Preceding gene: 108761314

Following gene: 108756873

Centisome position: 38.74

GC content: 68.92

Gene sequence:

>1245_bases
ATGACTGCCTTGTCGCAATCCGAGCCGTCCCTCTCCGCATCGTCCGACTCCTCCACCGACGCCCTGGTCCAGAAGGCGAA
GCGCCACCTGCTGCAGAACTACAAGCAGCCGCCCTTCGTCCTGGCTCGGGGCCAGGGGGCTCGTGTCTGGGACATGGATG
GCCGCGAGTACCTGGACCTGATTGGCGGCATCGCCACGTGCGCGCTGGGACACTGCCACCCGGAAGTCGTGGCTGCCGCG
AAGGCGCAACTGGATTCACTGTGGCACGTCTCCAACGTGTTCTATTCGCAGCCCCAGATTGACCTGGCCGCGCAGCTCAC
CGAGTGGTCCGGCCTGTCACGCGCGTTCTTCTGCAACTCGGGCGCGGAGGCGAACGAGGCGCTGCTCAAGCTGACGCGCA
AGGTGATGAAGGACCGCGGCACGCCGGAGCGCTTCGAGGTCATCTCCTTCGACAGCAGCTTCCACGGCCGCACCCTGGCC
ACCGTCACCGCCACCGGCCAGGCGAAGTACCAGAAGGGCTTCGAGCCGCTGCCCGCCGGCTTCACCCACGTGCCCTACGG
CGACCTCGAAGCGGTGCGCAAGGCCGTGGGCCCGGCGACCGCCGCCATCCTCGTGGAGCCCATCCAAGGGGAGGGCGGGG
TGCGCATGGCGCCCCTGGGTTTCCTCGTCGGTCTGCGCGCGCTGTGTGACGAGCACGGGCTGCTGCTGCTGGTGGACGAA
GTCCAGACGGGCATGGGCCGCACTGGCAAGCCGTTCGGCTTCATGCACGAGGGCATCGTCCCGGACGGCATCAGTGTGGC
GAAGGCGCTGGGCAACGGCCTGCCGATTGGCGCCATGCTCTGCAAGGAAGAGCTGGGCGCCAGCCTCACGCCGGGCACGC
ACGGCTCCACCTTTGGTGGCAACCCGGTGGCTGCGGCCGCCGCCAATGCCGTGGTGCGCATCCTCCGCCGTCCCGGTTTC
CTGGACGAGGTCCAGGAGAAGGGCGCCTATCTGCTCGCCCGGGCGCGTGAACTCCAGGGCCGGCTGCCTGCGGGTCGCAT
CCAGGCCGTGCGCGGCCAGGGGCTGCTGGTGGGCGTGGAGTTGGATCGCGAGGTGGCGCCCGTCATCGCCCAACTGCGCG
GAGAGGGGCTGCTGGTGAATGCCGCCGGCGACCGCACGCTGCGCTTCGCGCCGCCCTTCATCGTCACCGTGCGTGAGTTG
GATGAAGGTCTGTCCATTCTTGAGCGCGTGCTCGCCGCCAACTGA

Upstream 100 bases:

>100_bases
TACGTGCGCGAGCGCCTGGCCGCCATCGTCCAGGACGAGGACCTGTCGCGCTACATCCTGTAGCGCGCTATATGCGGAGG
GGTACCGTACCGCACGAAGG

Downstream 100 bases:

>100_bases
CCGGCGTGGCCGCGTTCCACCGCATGGGGAAGGGTTCACGGACGTTTGACGCCCTGCGTCCGGAACCCTAGTCTGGAAAC
TCCGGAAGGCTTTCCTCGGA

Product: acetylornithine transaminase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTALSQSEPSLSASSDSSTDALVQKAKRHLLQNYKQPPFVLARGQGARVWDMDGREYLDLIGGIATCALGHCHPEVVAAA
KAQLDSLWHVSNVFYSQPQIDLAAQLTEWSGLSRAFFCNSGAEANEALLKLTRKVMKDRGTPERFEVISFDSSFHGRTLA
TVTATGQAKYQKGFEPLPAGFTHVPYGDLEAVRKAVGPATAAILVEPIQGEGGVRMAPLGFLVGLRALCDEHGLLLLVDE
VQTGMGRTGKPFGFMHEGIVPDGISVAKALGNGLPIGAMLCKEELGASLTPGTHGSTFGGNPVAAAAANAVVRILRRPGF
LDEVQEKGAYLLARARELQGRLPAGRIQAVRGQGLLVGVELDREVAPVIAQLRGEGLLVNAAGDRTLRFAPPFIVTVREL
DEGLSILERVLAAN

Sequences:

>Translated_414_residues
MTALSQSEPSLSASSDSSTDALVQKAKRHLLQNYKQPPFVLARGQGARVWDMDGREYLDLIGGIATCALGHCHPEVVAAA
KAQLDSLWHVSNVFYSQPQIDLAAQLTEWSGLSRAFFCNSGAEANEALLKLTRKVMKDRGTPERFEVISFDSSFHGRTLA
TVTATGQAKYQKGFEPLPAGFTHVPYGDLEAVRKAVGPATAAILVEPIQGEGGVRMAPLGFLVGLRALCDEHGLLLLVDE
VQTGMGRTGKPFGFMHEGIVPDGISVAKALGNGLPIGAMLCKEELGASLTPGTHGSTFGGNPVAAAAANAVVRILRRPGF
LDEVQEKGAYLLARARELQGRLPAGRIQAVRGQGLLVGVELDREVAPVIAQLRGEGLLVNAAGDRTLRFAPPFIVTVREL
DEGLSILERVLAAN
>Mature_413_residues
TALSQSEPSLSASSDSSTDALVQKAKRHLLQNYKQPPFVLARGQGARVWDMDGREYLDLIGGIATCALGHCHPEVVAAAK
AQLDSLWHVSNVFYSQPQIDLAAQLTEWSGLSRAFFCNSGAEANEALLKLTRKVMKDRGTPERFEVISFDSSFHGRTLAT
VTATGQAKYQKGFEPLPAGFTHVPYGDLEAVRKAVGPATAAILVEPIQGEGGVRMAPLGFLVGLRALCDEHGLLLLVDEV
QTGMGRTGKPFGFMHEGIVPDGISVAKALGNGLPIGAMLCKEELGASLTPGTHGSTFGGNPVAAAAANAVVRILRRPGFL
DEVQEKGAYLLARARELQGRLPAGRIQAVRGQGLLVGVELDREVAPVIAQLRGEGLLVNAAGDRTLRFAPPFIVTVRELD
EGLSILERVLAAN

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=402, Percent_Identity=34.3283582089552, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=30.242825607064, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=35.2159468438538, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=28.0373831775701, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=26.9047619047619, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=26.8691588785047, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=27.9898218829517, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI188536080, Length=451, Percent_Identity=24.8337028824834, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38679950, Length=451, Percent_Identity=24.8337028824834, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38679946, Length=451, Percent_Identity=24.8337028824834, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789759, Length=394, Percent_Identity=43.6548223350254, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=44.5333333333333, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=39.119170984456, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=31.0747663551402, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=33.3333333333333, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1786991, Length=421, Percent_Identity=28.7410926365796, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786349, Length=325, Percent_Identity=31.3846153846154, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=418, Percent_Identity=31.3397129186603, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=29.9086757990868, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=33.0855018587361, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=466, Percent_Identity=26.8240343347639, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17541228, Length=481, Percent_Identity=25.7796257796258, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71981843, Length=196, Percent_Identity=29.0816326530612, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71992985, Length=144, Percent_Identity=31.25, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=35.264483627204, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=30.7692307692308, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321456, Length=389, Percent_Identity=25.4498714652956, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=461, Percent_Identity=23.8611713665944, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=419, Percent_Identity=31.5035799522673, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI28574759, Length=455, Percent_Identity=30.5494505494506, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI161085790, Length=459, Percent_Identity=30.2832244008715, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21356575, Length=459, Percent_Identity=29.4117647058824, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=23.1308411214953, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=23.1308411214953, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=23.1308411214953, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44000; Mature: 43869

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSQSEPSLSASSDSSTDALVQKAKRHLLQNYKQPPFVLARGQGARVWDMDGREYLDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHH
IGGIATCALGHCHPEVVAAAKAQLDSLWHVSNVFYSQPQIDLAAQLTEWSGLSRAFFCNS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECC
GAEANEALLKLTRKVMKDRGTPERFEVISFDSSFHGRTLATVTATGQAKYQKGFEPLPAG
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHCCCCCCCCC
FTHVPYGDLEAVRKAVGPATAAILVEPIQGEGGVRMAPLGFLVGLRALCDEHGLLLLVDE
CCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCEEEEEEC
VQTGMGRTGKPFGFMHEGIVPDGISVAKALGNGLPIGAMLCKEELGASLTPGTHGSTFGG
HHHCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
NPVAAAAANAVVRILRRPGFLDEVQEKGAYLLARARELQGRLPAGRIQAVRGQGLLVGVE
CCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHEEECCCEEEEEEE
LDREVAPVIAQLRGEGLLVNAAGDRTLRFAPPFIVTVRELDEGLSILERVLAAN
CCHHHHHHHHHHCCCCEEEECCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TALSQSEPSLSASSDSSTDALVQKAKRHLLQNYKQPPFVLARGQGARVWDMDGREYLDL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHH
IGGIATCALGHCHPEVVAAAKAQLDSLWHVSNVFYSQPQIDLAAQLTEWSGLSRAFFCNS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECC
GAEANEALLKLTRKVMKDRGTPERFEVISFDSSFHGRTLATVTATGQAKYQKGFEPLPAG
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHCCCCCCCCC
FTHVPYGDLEAVRKAVGPATAAILVEPIQGEGGVRMAPLGFLVGLRALCDEHGLLLLVDE
CCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCEEEEEEC
VQTGMGRTGKPFGFMHEGIVPDGISVAKALGNGLPIGAMLCKEELGASLTPGTHGSTFGG
HHHCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
NPVAAAAANAVVRILRRPGFLDEVQEKGAYLLARARELQGRLPAGRIQAVRGQGLLVGVE
CCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHEEECCCEEEEEEE
LDREVAPVIAQLRGEGLLVNAAGDRTLRFAPPFIVTVRELDEGLSILERVLAAN
CCHHHHHHHHHHCCCCEEEECCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12828649 [H]