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The map label for this gene is atoS [H]

Identifier: 108756970

GI number: 108756970

Start: 5211198

End: 5213321

Strand: Direct

Name: atoS [H]

Synonym: MXAN_4251

Alternate gene names: 108756970

Gene position: 5211198-5213321 (Clockwise)

Preceding gene: 108763070

Following gene: 108761773

Centisome position: 57.02

GC content: 70.57

Gene sequence:

>2124_bases
ATGCACGAGTTTCCTTCCCGTCGACAGTTGATGCTGGCCGTCCTGGTGGCCACGACTCTCTCCGCGGCTGTCGAGGGAGT
CTGGAGCTACTCCGGGGCGGTGAGCCCCCCTGCTCGCGTCCTCCTCACCGCCGCGGTGGGGCTGCTCATCAGCGGCACCC
TGGCGCTGTTGCTCCTGCGAACCCGGGAGCGCGCTCACCGCGCACGGGACGCCGCCCTGCGCAGCGCGGATGACGCCAGC
GCGCTTCGCGCAGCCGTCATGGACGTGACGCCCGTGGGCTTCGCCTTCTTCGACCGCGAGCTGCGCTACGTTCACATCAA
CACGGCCCTGGCGGCGATGCATGGCCTGCCCACGGAGCGGCACCTGGGCCGGCACGTCACCGAGGTGATGCCCGACCTGG
GCAAGCTCATCGCTCCGCGCCTCCAACTGGCGCTCAGCACGGGGGCCTCCATCCAGGACACCCTGCTCCAGGTGGAGACG
CCCGCCGCGCCGGGCGAAAGCCGCTTCTGGTTCGGCAGCTATCTGCGCGTGTGCGGCGCGAACGGCGAGGTGCTGGGCGT
CATCGCCGCGATGTCCGAGCTCACCGAGCGCATGCGCGCGGAGGAGAGCCTCCAGGAGCACGAGGGCCGGCTGGACGTGC
TGACGCGCTCGCTGCCGGACTACCTGTGGGGCGGCAAGCTGCGCGGCGGGAGGCTGCGCGATTTCTACTGCACGCCCGTC
ATCGAGCGCACCACCGGCTATGCCGCCTCCGCGTTCGTCCAGCCCGCACCGGATGGCGGACCGCCGCCGCTGTGGGCGGA
GATGATCCACCCCGAGGACCGCGCCCGCTACCGGGCCAGCATCGAGGGCCTGGCCCCCGGCGCCGAGGCGGAGCTGGAGC
ACCGGCTCATCTGCGCCGACGGCCGCGTGCGTTGGGTGCGCAGCCGCGCCGCCGCTTCCGCGTTGGATGCGCAGGCGGAG
CTGCATGTCGGCTGTGTCGTCACCGACATCACCGACCGGCGGCTCGCGGATGACCTGCGCCAGCGCCTGCATGACAGCTT
CCGCCGCTCCGCCCAGGAATGGCGCCGCACCTTCGACGCGGTGGCCTCGCCGCTGATGGTGTTGGGGGCGGATGGCACCG
TCCAGCGTCTCAACGCCGCCGCCATCGCGCTCTTCGGAGGCATGGACCCGTCCGGCCAGCCGCTGTTCACCGCGGCCAGT
GCCCCACCCTGGTCGCACGCACTGCCGTTGGTGGAGGAACTGCGCCGCACCCGCGCCAGCGCCACCCGCGAGCTGGGCGA
CCCGGTGTCGCGCCGCACGTGGGAGGTGTCCGCCACCTGGGTGGAGGAAGCCGGCGGCGAGGACTCGCGCATCATCCTGG
TGGCCACGGAGGTGACACGTCTCCTGGAGCTCCAGGCCAGCCTGCGGCGCAGTGAGACGATGGCCGCCATGGGCGCCATC
GTCGCGGGCGTGGCCCACGAGGTCCGCAACCCCCTCTTCTCCATCTCCGCGGTGGTCGACGCGGTGGAGGCCACCTTCGG
CGCGCGCGCGGAGCTCAAGCCCTACGTCGACGTGCTGCGCGGCGAGGTGAAGCGCCTCAACCACCTCACGCAGGAGCTCT
TCGAGTACGGCCGCCCCACCCGCGGCGAATGGGTGGAAGGTCCCGTGCTCCCGGTGATGATGGATGCACTCTCCGCATGT
GCCCTGGCCAGTGAACGCGCCGGTGTGAATGTGAATCGCGAATTGGCGGCGGAGCTGCCCCGCGTTCGAATGGACGCCCG
GCGTTTGTTTCACGTGTTTCGCAACGTGGTGGAGAACGCGGTGCAGCATTCACCGGCGGGCAGCGCGGTGCGGGTGGCGA
CGGAAGAAGTGAAAGAGGCGGGCCGGGCCTGGGTGCGGTGCACCGTGCGCGACGGTGGGCCGGGCTTTCGCGCGGAGGAC
CTGTCCCACGTCTTCGAGCCCTTCTTCAGCAAGCGGCGCGGCGGCACGGGGCTGGGCCTGTCCATCGTCCAACGCATCCT
GGAGGAGCATCAGGGTATCATCCGCTTGCGCAATCACCCGGAGGGCGGCGCGGAAGTCACACTGCTGCTTCCTGCTGTTT
CTTCGCGTGTATCAACCCAGCACGTAGACTCCCTGACTTCATGA

Upstream 100 bases:

>100_bases
TTCCCTCGTCCGCGGCGCCACCACGGCGGCACGCCAATGCCCGGCGAGCCACCGTCCGACCGGGGATTGCGGTTAAGCTC
CCACGCTCGCCGCCCACCGC

Downstream 100 bases:

>100_bases
CGCGCACCCGAATCCTTCTCGTGGACGACGAGCCCGGCATCCGCCTGGGCATGAGAGGCTTCCTCACCGCCCATGGGTTC
GACGTGGACGAGGCCACCAG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MHEFPSRRQLMLAVLVATTLSAAVEGVWSYSGAVSPPARVLLTAAVGLLISGTLALLLLRTRERAHRARDAALRSADDAS
ALRAAVMDVTPVGFAFFDRELRYVHINTALAAMHGLPTERHLGRHVTEVMPDLGKLIAPRLQLALSTGASIQDTLLQVET
PAAPGESRFWFGSYLRVCGANGEVLGVIAAMSELTERMRAEESLQEHEGRLDVLTRSLPDYLWGGKLRGGRLRDFYCTPV
IERTTGYAASAFVQPAPDGGPPPLWAEMIHPEDRARYRASIEGLAPGAEAELEHRLICADGRVRWVRSRAAASALDAQAE
LHVGCVVTDITDRRLADDLRQRLHDSFRRSAQEWRRTFDAVASPLMVLGADGTVQRLNAAAIALFGGMDPSGQPLFTAAS
APPWSHALPLVEELRRTRASATRELGDPVSRRTWEVSATWVEEAGGEDSRIILVATEVTRLLELQASLRRSETMAAMGAI
VAGVAHEVRNPLFSISAVVDAVEATFGARAELKPYVDVLRGEVKRLNHLTQELFEYGRPTRGEWVEGPVLPVMMDALSAC
ALASERAGVNVNRELAAELPRVRMDARRLFHVFRNVVENAVQHSPAGSAVRVATEEVKEAGRAWVRCTVRDGGPGFRAED
LSHVFEPFFSKRRGGTGLGLSIVQRILEEHQGIIRLRNHPEGGAEVTLLLPAVSSRVSTQHVDSLTS

Sequences:

>Translated_707_residues
MHEFPSRRQLMLAVLVATTLSAAVEGVWSYSGAVSPPARVLLTAAVGLLISGTLALLLLRTRERAHRARDAALRSADDAS
ALRAAVMDVTPVGFAFFDRELRYVHINTALAAMHGLPTERHLGRHVTEVMPDLGKLIAPRLQLALSTGASIQDTLLQVET
PAAPGESRFWFGSYLRVCGANGEVLGVIAAMSELTERMRAEESLQEHEGRLDVLTRSLPDYLWGGKLRGGRLRDFYCTPV
IERTTGYAASAFVQPAPDGGPPPLWAEMIHPEDRARYRASIEGLAPGAEAELEHRLICADGRVRWVRSRAAASALDAQAE
LHVGCVVTDITDRRLADDLRQRLHDSFRRSAQEWRRTFDAVASPLMVLGADGTVQRLNAAAIALFGGMDPSGQPLFTAAS
APPWSHALPLVEELRRTRASATRELGDPVSRRTWEVSATWVEEAGGEDSRIILVATEVTRLLELQASLRRSETMAAMGAI
VAGVAHEVRNPLFSISAVVDAVEATFGARAELKPYVDVLRGEVKRLNHLTQELFEYGRPTRGEWVEGPVLPVMMDALSAC
ALASERAGVNVNRELAAELPRVRMDARRLFHVFRNVVENAVQHSPAGSAVRVATEEVKEAGRAWVRCTVRDGGPGFRAED
LSHVFEPFFSKRRGGTGLGLSIVQRILEEHQGIIRLRNHPEGGAEVTLLLPAVSSRVSTQHVDSLTS
>Mature_707_residues
MHEFPSRRQLMLAVLVATTLSAAVEGVWSYSGAVSPPARVLLTAAVGLLISGTLALLLLRTRERAHRARDAALRSADDAS
ALRAAVMDVTPVGFAFFDRELRYVHINTALAAMHGLPTERHLGRHVTEVMPDLGKLIAPRLQLALSTGASIQDTLLQVET
PAAPGESRFWFGSYLRVCGANGEVLGVIAAMSELTERMRAEESLQEHEGRLDVLTRSLPDYLWGGKLRGGRLRDFYCTPV
IERTTGYAASAFVQPAPDGGPPPLWAEMIHPEDRARYRASIEGLAPGAEAELEHRLICADGRVRWVRSRAAASALDAQAE
LHVGCVVTDITDRRLADDLRQRLHDSFRRSAQEWRRTFDAVASPLMVLGADGTVQRLNAAAIALFGGMDPSGQPLFTAAS
APPWSHALPLVEELRRTRASATRELGDPVSRRTWEVSATWVEEAGGEDSRIILVATEVTRLLELQASLRRSETMAAMGAI
VAGVAHEVRNPLFSISAVVDAVEATFGARAELKPYVDVLRGEVKRLNHLTQELFEYGRPTRGEWVEGPVLPVMMDALSAC
ALASERAGVNVNRELAAELPRVRMDARRLFHVFRNVVENAVQHSPAGSAVRVATEEVKEAGRAWVRCTVRDGGPGFRAED
LSHVFEPFFSKRRGGTGLGLSIVQRILEEHQGIIRLRNHPEGGAEVTLLLPAVSSRVSTQHVDSLTS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=28.5318559556787, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=30.8016877637131, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=22.7040816326531, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=28.8065843621399, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=23.4309623430962, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790551, Length=220, Percent_Identity=30.9090909090909, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=23.3480176211454, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=23.1372549019608, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=27.4678111587983, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77150; Mature: 77150

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEFPSRRQLMLAVLVATTLSAAVEGVWSYSGAVSPPARVLLTAAVGLLISGTLALLLLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRERAHRARDAALRSADDASALRAAVMDVTPVGFAFFDRELRYVHINTALAAMHGLPTER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCEEEEEEHHHHHHHHCCCCHH
HLGRHVTEVMPDLGKLIAPRLQLALSTGASIQDTLLQVETPAAPGESRFWFGSYLRVCGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCCCHHHHHHHHHCC
NGEVLGVIAAMSELTERMRAEESLQEHEGRLDVLTRSLPDYLWGGKLRGGRLRDFYCTPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCH
IERTTGYAASAFVQPAPDGGPPPLWAEMIHPEDRARYRASIEGLAPGAEAELEHRLICAD
HHHCCCCHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECC
GRVRWVRSRAAASALDAQAELHVGCVVTDITDRRLADDLRQRLHDSFRRSAQEWRRTFDA
CCHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASPLMVLGADGTVQRLNAAAIALFGGMDPSGQPLFTAASAPPWSHALPLVEELRRTRAS
HCCCCEEECCCCHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ATRELGDPVSRRTWEVSATWVEEAGGEDSRIILVATEVTRLLELQASLRRSETMAAMGAI
HHHHHCCCHHCCEEEEEEHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVAHEVRNPLFSISAVVDAVEATFGARAELKPYVDVLRGEVKRLNHLTQELFEYGRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGEWVEGPVLPVMMDALSACALASERAGVNVNRELAAELPRVRMDARRLFHVFRNVVENA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VQHSPAGSAVRVATEEVKEAGRAWVRCTVRDGGPGFRAEDLSHVFEPFFSKRRGGTGLGL
HHCCCCCCEEHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SIVQRILEEHQGIIRLRNHPEGGAEVTLLLPAVSSRVSTQHVDSLTS
HHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHEFPSRRQLMLAVLVATTLSAAVEGVWSYSGAVSPPARVLLTAAVGLLISGTLALLLLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRERAHRARDAALRSADDASALRAAVMDVTPVGFAFFDRELRYVHINTALAAMHGLPTER
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCEEEEEEHHHHHHHHCCCCHH
HLGRHVTEVMPDLGKLIAPRLQLALSTGASIQDTLLQVETPAAPGESRFWFGSYLRVCGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCCCCHHHHHHHHHCC
NGEVLGVIAAMSELTERMRAEESLQEHEGRLDVLTRSLPDYLWGGKLRGGRLRDFYCTPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCH
IERTTGYAASAFVQPAPDGGPPPLWAEMIHPEDRARYRASIEGLAPGAEAELEHRLICAD
HHHCCCCHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECC
GRVRWVRSRAAASALDAQAELHVGCVVTDITDRRLADDLRQRLHDSFRRSAQEWRRTFDA
CCHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASPLMVLGADGTVQRLNAAAIALFGGMDPSGQPLFTAASAPPWSHALPLVEELRRTRAS
HCCCCEEECCCCHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ATRELGDPVSRRTWEVSATWVEEAGGEDSRIILVATEVTRLLELQASLRRSETMAAMGAI
HHHHHCCCHHCCEEEEEEHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVAHEVRNPLFSISAVVDAVEATFGARAELKPYVDVLRGEVKRLNHLTQELFEYGRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGEWVEGPVLPVMMDALSACALASERAGVNVNRELAAELPRVRMDARRLFHVFRNVVENA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VQHSPAGSAVRVATEEVKEAGRAWVRCTVRDGGPGFRAEDLSHVFEPFFSKRRGGTGLGL
HHCCCCCCEEHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
SIVQRILEEHQGIIRLRNHPEGGAEVTLLLPAVSSRVSTQHVDSLTS
HHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]