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The map label for this gene is clpX [H]

Identifier: 108756903

GI number: 108756903

Start: 4973606

End: 4974883

Strand: Reverse

Name: clpX [H]

Synonym: MXAN_4054

Alternate gene names: 108756903

Gene position: 4974883-4973606 (Counterclockwise)

Preceding gene: 108759135

Following gene: 108758926

Centisome position: 54.43

GC content: 63.77

Gene sequence:

>1278_bases
GTGAAGAAGGAGCACCACGTCAACCTGTCTTGTTCGTTCTGCGGCAAGTCGCAGCGCGAGGTCCGCAAGCTCATCGCGGG
CCCGACGGTCTACATCTGCGACGAATGCATCAAGCTGTGTAACGACATCATCGCGGACGAGAACGAGCGCGAGGAGGGCA
AGCCCCAGGTCAGCTTGCCGACGCCGGCGGAGATCAAGGCGTTCCTCGACGACTACGTCATCGGACAGGACCAGGCGAAG
AAGGTCCTCGCGGTGGCGGTGTACAACCACTACAAGCGCATCTATCAAAAGAAGCCGAACTCCCGGCCGCGTCCAGGCGT
GAAGGGCCCCACCGGCGAGGAAGTGGAGCTGAGCAAGAGCAACATCCTGCTCATCGGTCCCACGGGAAGTGGCAAGACGC
TGCTGGCCCAGTCGCTGGCGCGCTTCCTCAACGTGCCCTTCACCATCGCCGACGCCACCAGCCTCACCGAGGCCGGCTAC
GTGGGCGAGGACGTGGAGAACATCATCCAGAACCTCCTCCACAACGCCGACTACGACGTGGAGAAGGCCTCGCGCGGCAT
CGTCTACATCGACGAGATCGACAAGATCGCCCGCAAGGGTGACATGCCCAGCGCCACCCGCGACGTGGGCGGCGAGGGTG
TGCAGCAGGCCCTGCTGAAGATCATCGAAGGCACCCGGGCCAACGTCACGCCGCGCGGCGGGAAGAAGTACAACCAGCAG
GAGTACGTCCAGGTCGACACGACGAACATCCTGTTCATCTGCGGCGGCGCCTTCCACGGCATCGACGGCGTCATCAAGCG
CCGCGTGGGCGAGAAGGGCCTCGGCTTTGGCGCGAAGATCACCCACCGCGAGGAGCGCAGCGTGGGTGAGCTGCTGGCGC
TGACCGAGCCGGAAGACCTCATGCGCTTCGGCATGATTCCGGAGTTCATCGGCCGCCTGCCGATGATCGCCACGCTGAAC
GATCTGAAGGAAGAGGACCTGGTCATCATCCTCTCCCAGCCGAAGAACGCGCTGGTGAAGCAGTACCAGAAGCTCTTCGA
GTTCGAGAAGGTGAAGCTGACCTTCACCAAGGAGGCGCTGCGCGCCATCGCCCGCGAGGCGATGCGCCGCCACTCCGGAG
CGCGCGGTCTTCGCGCCATCCTGGAGGATGCCATGCTGGAGATCATGTACGACGTGCCGTTCCGCGAGGGCGTCAAGGAG
TGCAAGATCACCGAGCAGGTCATCACCAGGCACGAGGCGCCCCAGCTCGTCATGGAGAAGGAGAAGAAGACGGCCTAG

Upstream 100 bases:

>100_bases
CTGACGGCTGTTCGAGACGTGGGCAGGCCGTGCGGGTAGGGGAGCGGTGGACGGCGAAGGAGGCTCCGGGTGTCCGGAGC
CGGCGAACTCGGAGGCGGCA

Downstream 100 bases:

>100_bases
CGGCGGTCTCCCTTCTCCGGGTGTCCCAAGGCCCTGCTTTCCTCACGGAAGGCGGGGCCTTCGTTTTCAGGGCGCGGGCA
GCGTGACGATGAACTCGGCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKKEHHVNLSCSFCGKSQREVRKLIAGPTVYICDECIKLCNDIIADENEREEGKPQVSLPTPAEIKAFLDDYVIGQDQAK
KVLAVAVYNHYKRIYQKKPNSRPRPGVKGPTGEEVELSKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGY
VGEDVENIIQNLLHNADYDVEKASRGIVYIDEIDKIARKGDMPSATRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQQ
EYVQVDTTNILFICGGAFHGIDGVIKRRVGEKGLGFGAKITHREERSVGELLALTEPEDLMRFGMIPEFIGRLPMIATLN
DLKEEDLVIILSQPKNALVKQYQKLFEFEKVKLTFTKEALRAIAREAMRRHSGARGLRAILEDAMLEIMYDVPFREGVKE
CKITEQVITRHEAPQLVMEKEKKTA

Sequences:

>Translated_425_residues
MKKEHHVNLSCSFCGKSQREVRKLIAGPTVYICDECIKLCNDIIADENEREEGKPQVSLPTPAEIKAFLDDYVIGQDQAK
KVLAVAVYNHYKRIYQKKPNSRPRPGVKGPTGEEVELSKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGY
VGEDVENIIQNLLHNADYDVEKASRGIVYIDEIDKIARKGDMPSATRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQQ
EYVQVDTTNILFICGGAFHGIDGVIKRRVGEKGLGFGAKITHREERSVGELLALTEPEDLMRFGMIPEFIGRLPMIATLN
DLKEEDLVIILSQPKNALVKQYQKLFEFEKVKLTFTKEALRAIAREAMRRHSGARGLRAILEDAMLEIMYDVPFREGVKE
CKITEQVITRHEAPQLVMEKEKKTA
>Mature_425_residues
MKKEHHVNLSCSFCGKSQREVRKLIAGPTVYICDECIKLCNDIIADENEREEGKPQVSLPTPAEIKAFLDDYVIGQDQAK
KVLAVAVYNHYKRIYQKKPNSRPRPGVKGPTGEEVELSKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGY
VGEDVENIIQNLLHNADYDVEKASRGIVYIDEIDKIARKGDMPSATRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQQ
EYVQVDTTNILFICGGAFHGIDGVIKRRVGEKGLGFGAKITHREERSVGELLALTEPEDLMRFGMIPEFIGRLPMIATLN
DLKEEDLVIILSQPKNALVKQYQKLFEFEKVKLTFTKEALRAIAREAMRRHSGARGLRAILEDAMLEIMYDVPFREGVKE
CKITEQVITRHEAPQLVMEKEKKTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=305, Percent_Identity=51.8032786885246, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=64.8192771084337, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=118, Percent_Identity=41.5254237288136, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=417, Percent_Identity=37.8896882494005, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=325, Percent_Identity=44.3076923076923, Blast_Score=267, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=406, Percent_Identity=37.9310344827586, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=39.7590361445783, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=413, Percent_Identity=41.1622276029056, Blast_Score=285, Evalue=9e-78,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=47.3354231974922, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=47.3354231974922, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47436; Mature: 47436

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00055 RIBOSOMAL_S12

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEHHVNLSCSFCGKSQREVRKLIAGPTVYICDECIKLCNDIIADENEREEGKPQVSLP
CCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
TPAEIKAFLDDYVIGQDQAKKVLAVAVYNHYKRIYQKKPNSRPRPGVKGPTGEEVELSKS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
NILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGYVGEDVENIIQNLLHNADYDV
CEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCH
EKASRGIVYIDEIDKIARKGDMPSATRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQQ
HHHCCCEEEEHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EYVQVDTTNILFICGGAFHGIDGVIKRRVGEKGLGFGAKITHREERSVGELLALTEPEDL
CEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHCCCCHHHH
MRFGMIPEFIGRLPMIATLNDLKEEDLVIILSQPKNALVKQYQKLFEFEKVKLTFTKEAL
HHHCCCHHHHCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
RAIAREAMRRHSGARGLRAILEDAMLEIMYDVPFREGVKECKITEQVITRHEAPQLVMEK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
EKKTA
HHCCC
>Mature Secondary Structure
MKKEHHVNLSCSFCGKSQREVRKLIAGPTVYICDECIKLCNDIIADENEREEGKPQVSLP
CCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
TPAEIKAFLDDYVIGQDQAKKVLAVAVYNHYKRIYQKKPNSRPRPGVKGPTGEEVELSKS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
NILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGYVGEDVENIIQNLLHNADYDV
CEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCH
EKASRGIVYIDEIDKIARKGDMPSATRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQQ
HHHCCCEEEEHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EYVQVDTTNILFICGGAFHGIDGVIKRRVGEKGLGFGAKITHREERSVGELLALTEPEDL
CEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHCCCCHHHH
MRFGMIPEFIGRLPMIATLNDLKEEDLVIILSQPKNALVKQYQKLFEFEKVKLTFTKEAL
HHHCCCHHHHCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHH
RAIAREAMRRHSGARGLRAILEDAMLEIMYDVPFREGVKECKITEQVITRHEAPQLVMEK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
EKKTA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA