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The map label for this gene is dapE [H]

Identifier: 108756884

GI number: 108756884

Start: 303331

End: 304626

Strand: Direct

Name: dapE [H]

Synonym: MXAN_0255

Alternate gene names: 108756884

Gene position: 303331-304626 (Clockwise)

Preceding gene: 108764076

Following gene: 108756824

Centisome position: 3.32

GC content: 70.14

Gene sequence:

>1296_bases
ATGAAAGCTCTTGCCCTGCGTGAGGACCGCTTCCTCGACGTACTCCGGCGGCTCATCGCCCTGACTCCGAAGCTGCAGAA
CAACCCTGGCGCGGGGCTGGTGCCCGAGGAACGGCTGGCCGCGCAGGTAGTGCTGGACACCCTGGCGCCGCACATCGAGA
GCGGCTTCATCCAGGCGGAGTCCGTGGCGGGGCCGGGCCAGGCGTCGCGCCCCTGTCTGGTGCTGACCGTGCCGGGGGAG
GGAGAAGGCGCCATCGGCTTCGTCGGCGCGCACTTCGACGTGGTCCCCGCGGACCAGAAGACGGAGGGCTGGGAGCGCAG
CCCCTTCGAGCTGTGGGAGGGCCCCGGCGGCGTGCTCTACGGGCGCGGCGTCACCGACTGTCTGGGGCACGTCGCCGTGC
TCACCGACCTGCTGGCCCAGCTGGCCGAGCGCAAGGTGCGCCCCAGCCGCACGCTGAAGGTGGTGCTCATCTCCAACGAG
GAGTCCTCGGAGCTGCCGGGCCTGGGCCTCAACTACGTGGCCGAGCAGGGCATGCTCAAGCCGCTCGATGGCCAGCCGGT
GTACTGGCTGGACAGTGCCAACTTCGGCCCCACGCTGGGCACGGCGGGCGTGTCGCTGTGGGAGCTGAAGGTGACGGGCG
TGGGGGGCCACTCCGGCATGCCGCAGAACTGCGTCAACGCGCTGGAGTTGGGCATGGCCGCGTCGTTGGAGCTGGCGCGC
TTCTTCCACGAGCGCTTCCCGCCCACGGAGGACGAGAAGCGCTGGGGCTTCCTCTCGTCCTCCAGTCTCAAGGCCACCGT
GGTGGAGGCGCCCAACACCAAGGAGACGAAGGTGCCCGCCGACGTCGTCCTGCGCGGCGACATCCGCCTCACGCCCTTCT
ACGACCTGGCGGAGGTGCAGAAGACTGTGACGGACTTCATGGCGGAGCTCGACGCCCGACTGGAGCGCGACGATGCCCCC
GCGCACTTCCCGCGCACGCGCACGGCGGGCGGCAAGCGCGGTGAGCTGGCGTTCCGCTTCCAGGGGGAGGGGACCGAGGG
CATCGCCTGCCGGCTGGACTCGGAGGGCCTGCGCGCACTGAAGGAGGCCATGCAGGTGGTGCGCGGTGTGTCGGCCACGC
CCTTCTCGCTCACCGGCTCGCTGCCGCTCGTGAGGGACCTGCAACGACAGGGCTGCGACGTGCAGATTACGGGCTTCGGG
GACATGCAGTACTACCACGCCCCCAATGAGCAGGCCCGGCTGGAGGACTTCCGGCAGGGCTTCGCGATTCTCCGCGAACT
GCTCGTCCGCCTCTGA

Upstream 100 bases:

>100_bases
TCCACCGCTCCACGATGGACCCGCCAGTTCCCCCGTATCGGCGGCGGCGCCTGTTCGTTTCCGGTGACTTCCACCGCGCG
TCTGGGCTCCAATCTGTTTC

Downstream 100 bases:

>100_bases
GGCGGGGCGCGTCTGGTGGCGTGCTGTTCGGAAATGTCGGGGGTTTTGCGCGGCGAATGTCCCGACATTTCCGAATAGCG
CGCACCGGACACTCGCCCGG

Product: M20 family peptidase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKALALREDRFLDVLRRLIALTPKLQNNPGAGLVPEERLAAQVVLDTLAPHIESGFIQAESVAGPGQASRPCLVLTVPGE
GEGAIGFVGAHFDVVPADQKTEGWERSPFELWEGPGGVLYGRGVTDCLGHVAVLTDLLAQLAERKVRPSRTLKVVLISNE
ESSELPGLGLNYVAEQGMLKPLDGQPVYWLDSANFGPTLGTAGVSLWELKVTGVGGHSGMPQNCVNALELGMAASLELAR
FFHERFPPTEDEKRWGFLSSSSLKATVVEAPNTKETKVPADVVLRGDIRLTPFYDLAEVQKTVTDFMAELDARLERDDAP
AHFPRTRTAGGKRGELAFRFQGEGTEGIACRLDSEGLRALKEAMQVVRGVSATPFSLTGSLPLVRDLQRQGCDVQITGFG
DMQYYHAPNEQARLEDFRQGFAILRELLVRL

Sequences:

>Translated_431_residues
MKALALREDRFLDVLRRLIALTPKLQNNPGAGLVPEERLAAQVVLDTLAPHIESGFIQAESVAGPGQASRPCLVLTVPGE
GEGAIGFVGAHFDVVPADQKTEGWERSPFELWEGPGGVLYGRGVTDCLGHVAVLTDLLAQLAERKVRPSRTLKVVLISNE
ESSELPGLGLNYVAEQGMLKPLDGQPVYWLDSANFGPTLGTAGVSLWELKVTGVGGHSGMPQNCVNALELGMAASLELAR
FFHERFPPTEDEKRWGFLSSSSLKATVVEAPNTKETKVPADVVLRGDIRLTPFYDLAEVQKTVTDFMAELDARLERDDAP
AHFPRTRTAGGKRGELAFRFQGEGTEGIACRLDSEGLRALKEAMQVVRGVSATPFSLTGSLPLVRDLQRQGCDVQITGFG
DMQYYHAPNEQARLEDFRQGFAILRELLVRL
>Mature_431_residues
MKALALREDRFLDVLRRLIALTPKLQNNPGAGLVPEERLAAQVVLDTLAPHIESGFIQAESVAGPGQASRPCLVLTVPGE
GEGAIGFVGAHFDVVPADQKTEGWERSPFELWEGPGGVLYGRGVTDCLGHVAVLTDLLAQLAERKVRPSRTLKVVLISNE
ESSELPGLGLNYVAEQGMLKPLDGQPVYWLDSANFGPTLGTAGVSLWELKVTGVGGHSGMPQNCVNALELGMAASLELAR
FFHERFPPTEDEKRWGFLSSSSLKATVVEAPNTKETKVPADVVLRGDIRLTPFYDLAEVQKTVTDFMAELDARLERDDAP
AHFPRTRTAGGKRGELAFRFQGEGTEGIACRLDSEGLRALKEAMQVVRGVSATPFSLTGSLPLVRDLQRQGCDVQITGFG
DMQYYHAPNEQARLEDFRQGFAILRELLVRL

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 46896; Mature: 46896

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALALREDRFLDVLRRLIALTPKLQNNPGAGLVPEERLAAQVVLDTLAPHIESGFIQAE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
SVAGPGQASRPCLVLTVPGEGEGAIGFVGAHFDVVPADQKTEGWERSPFELWEGPGGVLY
CCCCCCCCCCCEEEEEECCCCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHCCCCCEEE
GRGVTDCLGHVAVLTDLLAQLAERKVRPSRTLKVVLISNEESSELPGLGLNYVAEQGMLK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCC
PLDGQPVYWLDSANFGPTLGTAGVSLWELKVTGVGGHSGMPQNCVNALELGMAASLELAR
CCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FFHERFPPTEDEKRWGFLSSSSLKATVVEAPNTKETKVPADVVLRGDIRLTPFYDLAEVQ
HHHHHCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCHHEEEECCEEECCCHHHHHHH
KTVTDFMAELDARLERDDAPAHFPRTRTAGGKRGELAFRFQGEGTEGIACRLDSEGLRAL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHH
KEAMQVVRGVSATPFSLTGSLPLVRDLQRQGCDVQITGFGDMQYYHAPNEQARLEDFRQG
HHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHHHHHHH
FAILRELLVRL
HHHHHHHHHCC
>Mature Secondary Structure
MKALALREDRFLDVLRRLIALTPKLQNNPGAGLVPEERLAAQVVLDTLAPHIESGFIQAE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
SVAGPGQASRPCLVLTVPGEGEGAIGFVGAHFDVVPADQKTEGWERSPFELWEGPGGVLY
CCCCCCCCCCCEEEEEECCCCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHCCCCCEEE
GRGVTDCLGHVAVLTDLLAQLAERKVRPSRTLKVVLISNEESSELPGLGLNYVAEQGMLK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCC
PLDGQPVYWLDSANFGPTLGTAGVSLWELKVTGVGGHSGMPQNCVNALELGMAASLELAR
CCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FFHERFPPTEDEKRWGFLSSSSLKATVVEAPNTKETKVPADVVLRGDIRLTPFYDLAEVQ
HHHHHCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCHHEEEECCEEECCCHHHHHHH
KTVTDFMAELDARLERDDAPAHFPRTRTAGGKRGELAFRFQGEGTEGIACRLDSEGLRAL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHH
KEAMQVVRGVSATPFSLTGSLPLVRDLQRQGCDVQITGFGDMQYYHAPNEQARLEDFRQG
HHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHHHHHHH
FAILRELLVRL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA