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The map label for this gene is yaeL [C]

Identifier: 108756877

GI number: 108756877

Start: 2976597

End: 2978264

Strand: Direct

Name: yaeL [C]

Synonym: MXAN_2557

Alternate gene names: 108756877

Gene position: 2976597-2978264 (Clockwise)

Preceding gene: 108761978

Following gene: 108758400

Centisome position: 32.57

GC content: 68.35

Gene sequence:

>1668_bases
TTGTCCGCCTGGGCGCCCACGATTACTGTTGCGCCCATGCTCCAAAACATCGGGTTCTTCGTCATTCTGCTCGGCGTGCT
CGTCACGGTGCACGAGCTTGGCCACTTCCTGGTGGCGAAGGCCTGTGGTGTGAAGGTCCTGAAGTTCTCCATCGGCTTCG
GACCCAAGTTGATCGGCTTCACCAAGGGCGAGACGGAGTACCAGATTGCCCTGCTGCCGCTGGGCGGCTACGTGAAGATG
GCGGGCGACATGCCCCACGAGGAGCTCAGCCCGGAGGAGGCCAGCCGGGGCTTCCTGGCGCAGCCCCCATGGAAGCGCGG
CCTCATCGTCCTGGCGGGGCCGGCCTTCAACCTCATCTTCCCCATCCTCGTCTATTTCTTCGTCTTCCTGGGCCCGCACC
AGGCCACGTCCACCTACGTGGGGACGGTGAGCGAGGGCATGCCCGCGCAGGCCGCCGGCATCCGCCCTGGAGACCGCATC
CTGTCCGTGGATGGCGAGCCGGTACGCACGTTCAACGACATGCGGGAGGCGTTCGTCGGCCGCTTCGAGCGGCCCGTCCC
CATCGTCCTGGAGCGCAATGGCCAGAAGCTGACGCTGGACGTGACGCCCACGAAGAACGTGGAGACGTCCCCCATCGACA
CGGTGGAGCGCGGCTCCATTGGCGTGGAGGCCGTGTCGAAGCCGCCCATCGTCGGCGTGCCGCCGGGCTCGGTGGCGGAG
CAGGCCGGACTGCGGACCTTCGACCGCATCCTGGCCGTCAACGGCGTGAGCGTGGAGACGGAAGCGCGCTTCCAGCAGGA
GCTGGACAAGCACGCGGAGGGCACGCCCCTGGAGCTCACCCTCCGGCGCATGGACTCCGTGGCGGCGGGCGTCGTGACGG
GGCGGGTACCCTCCGTGCTGAAGCTCACCGTGCCGAAGCAGCCGGGAGTGGGGCTGGCGACGGTGGGCGCGGAGACGTCC
GACCTGTACCTGGCCACCGTGGCGCCGGGGAGCGCGGCCGAGAAGGGCGGCCTGCGGCCCGGAGACCGCATCATCGCCCT
GGATGGCGAGAAGCCGGAGTCCTTCGTCAAGTTCTCCTCGAAGCTGAACGCCCTGAAGGAGCGTTCCTTCCAGTTGACGT
GGCGGGGCGCTGACGGCGAGCGCACGGAGACGCTGGCGCAGGCGCCGCTGAAGACGGAGGACGAGATGGGCACGGCGAGC
TCGCCCATCGTCCTGGGCGTGCGCAACTGGGTGCTCTCCGCGGCGGACATGCCGGTGCTGGACGAGGTGACGGTGCATCT
GGGGCCGGGCGCCGCGCTGAAGCAGGCCGCGCTCATCGTCCCGAAGATTGTCGGGCAGATGGTGCGGGTCCTCGGCGGGC
TGCTGGTGGGCTCGGTGCCGATGAACACCGTGGGCGGCCCCATCATGATGTACCAACTGGCGTCGAAGAGCGCCGAGCAG
GGCCTGGACAGCTTCCTCCACCTGATGGCGCTCATCTCCATCAACCTGGGGGTGATGAACCTGTTGCCCATCCCCGTGCT
GGACGGCTTCCACCTGCTTTCCGCCGCCTGGGAGGGAATTCGCCGCCGCCCCATCCCTGTTCGCGTCCGCGAGGTGGCCA
ACATGGTGGGGCTCGCGCTGCTCGTCCTGCTGATGCTGTTGGCCGTGACCAACGACATCACCCGCTAG

Upstream 100 bases:

>100_bases
CGCGCCCCTGGTGTTCGTCTACGTGCAGTTCGTCCGGGGTCTGCTGCCCTAGGGACCGCCCCTTCCGGCTGCCCGTCTGC
TCGGCGGGCCCGGTTGCGCG

Downstream 100 bases:

>100_bases
AGGACGCATGCGAGGAATCGCCGTTGCCGGATTGCTCTGCTTCGGTTTCACCTCCGCGTGCGCCTCGCGCGCGGCCAGGC
CCGACCCGGTGGAGGAACCC

Product: M50A family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSAWAPTITVAPMLQNIGFFVILLGVLVTVHELGHFLVAKACGVKVLKFSIGFGPKLIGFTKGETEYQIALLPLGGYVKM
AGDMPHEELSPEEASRGFLAQPPWKRGLIVLAGPAFNLIFPILVYFFVFLGPHQATSTYVGTVSEGMPAQAAGIRPGDRI
LSVDGEPVRTFNDMREAFVGRFERPVPIVLERNGQKLTLDVTPTKNVETSPIDTVERGSIGVEAVSKPPIVGVPPGSVAE
QAGLRTFDRILAVNGVSVETEARFQQELDKHAEGTPLELTLRRMDSVAAGVVTGRVPSVLKLTVPKQPGVGLATVGAETS
DLYLATVAPGSAAEKGGLRPGDRIIALDGEKPESFVKFSSKLNALKERSFQLTWRGADGERTETLAQAPLKTEDEMGTAS
SPIVLGVRNWVLSAADMPVLDEVTVHLGPGAALKQAALIVPKIVGQMVRVLGGLLVGSVPMNTVGGPIMMYQLASKSAEQ
GLDSFLHLMALISINLGVMNLLPIPVLDGFHLLSAAWEGIRRRPIPVRVREVANMVGLALLVLLMLLAVTNDITR

Sequences:

>Translated_555_residues
MSAWAPTITVAPMLQNIGFFVILLGVLVTVHELGHFLVAKACGVKVLKFSIGFGPKLIGFTKGETEYQIALLPLGGYVKM
AGDMPHEELSPEEASRGFLAQPPWKRGLIVLAGPAFNLIFPILVYFFVFLGPHQATSTYVGTVSEGMPAQAAGIRPGDRI
LSVDGEPVRTFNDMREAFVGRFERPVPIVLERNGQKLTLDVTPTKNVETSPIDTVERGSIGVEAVSKPPIVGVPPGSVAE
QAGLRTFDRILAVNGVSVETEARFQQELDKHAEGTPLELTLRRMDSVAAGVVTGRVPSVLKLTVPKQPGVGLATVGAETS
DLYLATVAPGSAAEKGGLRPGDRIIALDGEKPESFVKFSSKLNALKERSFQLTWRGADGERTETLAQAPLKTEDEMGTAS
SPIVLGVRNWVLSAADMPVLDEVTVHLGPGAALKQAALIVPKIVGQMVRVLGGLLVGSVPMNTVGGPIMMYQLASKSAEQ
GLDSFLHLMALISINLGVMNLLPIPVLDGFHLLSAAWEGIRRRPIPVRVREVANMVGLALLVLLMLLAVTNDITR
>Mature_554_residues
SAWAPTITVAPMLQNIGFFVILLGVLVTVHELGHFLVAKACGVKVLKFSIGFGPKLIGFTKGETEYQIALLPLGGYVKMA
GDMPHEELSPEEASRGFLAQPPWKRGLIVLAGPAFNLIFPILVYFFVFLGPHQATSTYVGTVSEGMPAQAAGIRPGDRIL
SVDGEPVRTFNDMREAFVGRFERPVPIVLERNGQKLTLDVTPTKNVETSPIDTVERGSIGVEAVSKPPIVGVPPGSVAEQ
AGLRTFDRILAVNGVSVETEARFQQELDKHAEGTPLELTLRRMDSVAAGVVTGRVPSVLKLTVPKQPGVGLATVGAETSD
LYLATVAPGSAAEKGGLRPGDRIIALDGEKPESFVKFSSKLNALKERSFQLTWRGADGERTETLAQAPLKTEDEMGTASS
PIVLGVRNWVLSAADMPVLDEVTVHLGPGAALKQAALIVPKIVGQMVRVLGGLLVGSVPMNTVGGPIMMYQLASKSAEQG
LDSFLHLMALISINLGVMNLLPIPVLDGFHLLSAAWEGIRRRPIPVRVREVANMVGLALLVLLMLLAVTNDITR

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=285, Percent_Identity=34.7368421052632, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 59248; Mature: 59117

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAWAPTITVAPMLQNIGFFVILLGVLVTVHELGHFLVAKACGVKVLKFSIGFGPKLIGF
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEE
TKGETEYQIALLPLGGYVKMAGDMPHEELSPEEASRGFLAQPPWKRGLIVLAGPAFNLIF
CCCCCEEEEEEEECCCEEEECCCCCHHHCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHH
PILVYFFVFLGPHQATSTYVGTVSEGMPAQAAGIRPGDRILSVDGEPVRTFNDMREAFVG
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
RFERPVPIVLERNGQKLTLDVTPTKNVETSPIDTVERGSIGVEAVSKPPIVGVPPGSVAE
HCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCHHHH
QAGLRTFDRILAVNGVSVETEARFQQELDKHAEGTPLELTLRRMDSVAAGVVTGRVPSVL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
KLTVPKQPGVGLATVGAETSDLYLATVAPGSAAEKGGLRPGDRIIALDGEKPESFVKFSS
EEECCCCCCCCEEEECCCCCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHH
KLNALKERSFQLTWRGADGERTETLAQAPLKTEDEMGTASSPIVLGVRNWVLSAADMPVL
HHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCC
DEVTVHLGPGAALKQAALIVPKIVGQMVRVLGGLLVGSVPMNTVGGPIMMYQLASKSAEQ
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GLDSFLHLMALISINLGVMNLLPIPVLDGFHLLSAAWEGIRRRPIPVRVREVANMVGLAL
HHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LVLLMLLAVTNDITR
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAWAPTITVAPMLQNIGFFVILLGVLVTVHELGHFLVAKACGVKVLKFSIGFGPKLIGF
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEE
TKGETEYQIALLPLGGYVKMAGDMPHEELSPEEASRGFLAQPPWKRGLIVLAGPAFNLIF
CCCCCEEEEEEEECCCEEEECCCCCHHHCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHH
PILVYFFVFLGPHQATSTYVGTVSEGMPAQAAGIRPGDRILSVDGEPVRTFNDMREAFVG
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
RFERPVPIVLERNGQKLTLDVTPTKNVETSPIDTVERGSIGVEAVSKPPIVGVPPGSVAE
HCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCHHHH
QAGLRTFDRILAVNGVSVETEARFQQELDKHAEGTPLELTLRRMDSVAAGVVTGRVPSVL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
KLTVPKQPGVGLATVGAETSDLYLATVAPGSAAEKGGLRPGDRIIALDGEKPESFVKFSS
EEECCCCCCCCEEEECCCCCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHH
KLNALKERSFQLTWRGADGERTETLAQAPLKTEDEMGTASSPIVLGVRNWVLSAADMPVL
HHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCC
DEVTVHLGPGAALKQAALIVPKIVGQMVRVLGGLLVGSVPMNTVGGPIMMYQLASKSAEQ
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
GLDSFLHLMALISINLGVMNLLPIPVLDGFHLLSAAWEGIRRRPIPVRVREVANMVGLAL
HHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LVLLMLLAVTNDITR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]