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The map label for this gene is secD [H]

Identifier: 108563924

GI number: 108563924

Start: 1560399

End: 1561976

Strand: Reverse

Name: secD [H]

Synonym: HPAG1_1499

Alternate gene names: 108563924

Gene position: 1561976-1560399 (Counterclockwise)

Preceding gene: 108563925

Following gene: 108563923

Centisome position: 97.85

GC content: 43.54

Gene sequence:

>1578_bases
ATGAAACTTTTTAACGCTCGTTTAATCGTTTTTATTTGCGCGCTTCTTTTAGGGGTGGGGTTTTCTGTGCCTTCTTTGCT
AGAAACTAAAGGCCCTAAAATCACTTTAGGTTTGGATTTAAGGGGGGGGTTAAACATGCTTTTAGGGGTGCAAACCGATG
AGGCTTTAAAAAACAAGTATTTAAGCTTGGCGTCCGCTTTAGAATACAACGCTAAAAAGCAAAATATCTTGCTTAAAGAC
ATTAAATCCAGCCTAGAAGGGATCAGTTTTGAGCTTTTAGATGAAGATGAAGCGAAAAAATTAGACGCGCTTTTATTGGA
ATTGCAAGGTCATAGCCAGTTTGAAATCAAAAAAGAAGCGGAATTTTATAGCGTGAAACTCACCCCTTTAGAGCAAGAGG
AATTGCGTAAAAACACGATTTTGCAAGTGATAGGGATCATTCGTAACCGCTTGGATCAATTTGGTTTGGCAGAGCCTGTA
GTCATTCAGCAAGGTAAAGAAGAAATTTCGGTGCAATTGCCTGGCATTAAGACTTTAGAAGAAGAACGGCGCGCTAAAGA
CTTGATTTCAAGATCCGCTCATTTGCAGATGATGGCGGTGGATGAAGAGCACAATAAAGATGCGATGAAAATGACGGATT
TAGAGGCTCAAAAGTTAGGCAGTGTGTTGTTACCGGATGTGGAAATGGGGGGTAAAATCTTACTCAAAGCGATCCCTATT
TTAGATGGCGAAATGCTTACAGACGCGAAAGTGGTGTATGATCAAAACAACCAGCCGGTGGTGAGCTTCACGCTGGATGC
GCAAGGGGCTAAGATTTTTGGGGATTTCTCAGGTGCGAATGTGGGCAAACGCATGGCGATCGTTTTAGACAATAAGGTTT
ATTCAGCCCCGGTGATTAGAGAGCGTATTGGTGGGGGGAGCGGGCAGATTAGCGGGAATTTTAGCGTGGCTCAAGCGAGC
GATTTAGCGATCGCTTTAAGGAGTGGGGCGATGAGCGCTCCCATTCAGGTTTTAGAAAAAAGAATTATAGGCCCAAGTTT
AGGGAAAGACAGCATTAAAACTTCCATTATCGCTCTGGTTGGGGGCTTTATTTTAGTGATGGGCTTTATGGCGCTTTATT
ACTCTATGGCGGGGGTGATCGCTTGTTTGGCGTTAGTGGTCAATCTTTTTTTGATTGTGGCGGTCATGGCGATTTTTGGA
GCAACGCTGACTTTACCGGGAATGGCAGGGATTGTTTTAACCGTGGGGATTGCCGTGGATGCTAATATCATTATCAACGA
GCGCATTAGAGAAGCCTTAAGAGAGAATGAGGGCATCGCTAAAGCGATCCATTTGGGCTATATCAATGCGAGTCGGGCGA
TTTTTGATTCTAATATCACTTCCTTGATCGCTTCAGTGTTGTTATACGCTTATGGCACAGGAGCGATCAAAGGCTTTGCC
CTAACCACAGGCATTGGGATTTTAGCCTCTATTATCACCGCTATTGTAGGCACGCAAGGGATTTATCAAGCCCTTTTGCC
TAAACTCACTCAAACAAAAAGCCTTTATTTTTGGTTTGGCGTGAACAAAAGAGCTTAG

Upstream 100 bases:

>100_bases
TTTTTTTAGCGTGAAACTCAATGATGACACCACCGCTAAACTTTCTAAAAACTATATAGCGTTCAAATTAGACGAAGAAA
CAACACCCAACAACAACTAA

Downstream 100 bases:

>100_bases
GAGGTTTTATGGAATTATTCAAACAAACTAGAATCTTAAACTTCATGCGTTATTCCAATTATGGGGTGATTGTTTCAGCG
ATATTAGCGCTTCTGGCGTT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKLFNARLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLPDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREALRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Sequences:

>Translated_525_residues
MKLFNARLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLPDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREALRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
>Mature_525_residues
MKLFNARLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLPDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREALRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=499, Percent_Identity=37.4749498997996, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 56652; Mature: 56652

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFNARLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGKEEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLPDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHCCCEECCCCCCCCEEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALV
HHCCCCCCEECCCEEEECCCCHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREALRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CEEEEHHHHHHHHHHCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC
>Mature Secondary Structure
MKLFNARLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGKEEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLPDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHCCCEECCCCCCCCEEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALV
HHCCCCCCEECCCEEEECCCCHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVMGFMALYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREALRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CEEEEHHHHHHHHHHCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]