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The map label for this gene is hsdM [H]

Identifier: 108563889

GI number: 108563889

Start: 1522146

End: 1524158

Strand: Reverse

Name: hsdM [H]

Synonym: HPAG1_1464

Alternate gene names: 108563889

Gene position: 1524158-1522146 (Counterclockwise)

Preceding gene: 108563890

Following gene: 108563888

Centisome position: 95.48

GC content: 37.41

Gene sequence:

>2013_bases
ATGCGCCATTTCGCTAGCGAGTCCGGTAAATCCAAAGGGCAGTTTTACACCCCTAGCGAAGTTTCGCTTTTATTATCCCT
TTTGCTTGGCATTGATGAAAACACCAGGCAGGATAAAAGCATCTATGATCCCACTTGCGGGAGCGGTTCGTTATTACTAA
AAGCTTCTAGCTTGGCCGGTAAAAACGGCTTAACTATCTATGGTCAAGAAAAAGACATTTCCACCACAGCCCTTTGTAAA
ATGAATATGATTTTACACAATAGTGCTGATGCTGATATTGCTAAAGGGGGTTCTAGCACCCTTTCTAACCCCCTTTTTAC
TACTGAAAATGGCATGCTAAAAACCTTTGATTATGTTGTGGCTAACCCTCCCTTTAGCTTGAAAAACTGGACTGATGGGC
TAAGCATAGACCCCAAAAGCAAGCAAGTCATTAATGATCATTTCAATCGTTTTGAAGACGGCACGCCCCCTGAAAAAAAT
GGCGATTTCGCTTTTTTGCTCCACATCATCAAATCCTTAAAAAACACAGGCAAAGGGGCAGTGATTTTACCCCATGGGGT
GCTATTTAGGGGGAATGCTGAGGGTGTAATTAGAAAAAATCTTTTAACAAAAGGCTATATTAAAGGCGTGATAGGCCTAG
CCCCTAACCTTTTTTATGGCACTTCCATTCCTGCATGCGTGATTGTTTTAGACAAAAAAAATGCGCGCGCCAGAAAGGGC
GTTTTTGTGATAGATGCGAGCAAGGATTTTAAAAAAGACGGCAATAAAAACCGCTTGAGGGAGCAAGATGTCCAAAAAAT
GATAGACACTTTTAACGCTTTAAAAGAAATCCCTTATTATTCCAAAATGGTAAGCCTAGAAGAAATTAGCGCTAACGACT
ATAACTTGAATATCCCGCGCTACATTGCCGCCAAGCAAGAATCAGAAAAAGACTTGTTCGCTTTAATCAACAGCCCTAGT
TATTTGCCCAAAAACGAAATAAACCTCTACGCCCCTTATTTTAGAGTGTTTAAAGAGCTTAAAAACACGCTTTTTAAAAA
GAGCGATAAAGAGGGTTATTACGCTTTAAAAACAGAATGCGAAAACATTAAAGATTACATCACCCAAAGCTCAGAATTCC
AAGCTTTCCACGCTTCTGTTTTAAGCGCTTTTGACCGATTGGATTTATTTGAAACTTTTGAGCATTTAGAGCCAGGTTTT
AACCCAAAAACCCTCATAGAAAGCGTTTGTTCAAGAGTTTTAAAAGAATTTGAAAAGGGTGAAATTTTAGACAAATACGG
CGTGTATCAGCTCTTTAAAGATTACTACAACGAAGTCTTGCAAGACGACTGGTTTCTTCTTTCATTCAATGGCTTTAGAA
GCGCTAAAGAATTAAGGAAATTAACCCCCCTAAAAGACAAAAACAAAAAAGCCAATTATTTAGAGGAGCCGGATTTTGTC
ATTCAAAAAACCTACTATAAAAGCGATCTAATCCCTAAACATTTAATCAAACAACGCTTTTTTGAAAAAGAAACAAAAGA
ATTAGAAGAATTAGAAAACGCCCTCAACGAAAAAGAGGCTCTTTTAGATGAATTTATAGAAGAGCATTCTAACGAAGAGG
GGCTTTTTTATGAATTGAAAATCAATGAAAGCGTTTTGAAAAAAGAGCTAAAAAACGCCACCGATTCAGAAGATAAAAAA
ATCCTAAAAACCGCTTTAGAATTACTAGAGGCTAAAAACAAGGCGCTAAAAATTAAAAATAAAGCTTATGAGGAGCTGGA
ATTAAAAGCGTTCCACCAATACGAAAAGCTTGAAATCAATGAAATTAAGGATCTCATCATCAAAGACAAATGGCTTAACA
GCCTAAAAAACGCCCTAGAAAACAAGATTCAAAAACGCATCAACGCTTTTATTAGTGCCCTTAATGGAATCATTCAAACT
TACTCTAACAGCTTGTTAGAACTAGACAAAGAAGTCAAAGAGAGCGAATCAAAAGTTTTAGAGCATTTGAAAGATTTGGG
GATTGTCGTTTGA

Upstream 100 bases:

>100_bases
TAGACACCCTTTCTAATTTGGTTAAAATCTTTGCGGATTTGAGTTTGGGCGCGCATGGGGCTTAGACGATGATTTACTGG
GCGATGCATACGAATATTTA

Downstream 100 bases:

>100_bases
TATTAAAAAGTTTGGAGTGCCTTTTGACTAGCGTATCCTCGCTATGAGACCTCCAAACTAGAAGAGATTATAGCACAGGA
AATTTAATGGAACTTGAAAA

Product: type I restriction enzyme M protein

Products: NA

Alternate protein names: M.EcoR124II [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MRHFASESGKSKGQFYTPSEVSLLLSLLLGIDENTRQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCK
MNMILHNSADADIAKGGSSTLSNPLFTTENGMLKTFDYVVANPPFSLKNWTDGLSIDPKSKQVINDHFNRFEDGTPPEKN
GDFAFLLHIIKSLKNTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGVIGLAPNLFYGTSIPACVIVLDKKNARARKG
VFVIDASKDFKKDGNKNRLREQDVQKMIDTFNALKEIPYYSKMVSLEEISANDYNLNIPRYIAAKQESEKDLFALINSPS
YLPKNEINLYAPYFRVFKELKNTLFKKSDKEGYYALKTECENIKDYITQSSEFQAFHASVLSAFDRLDLFETFEHLEPGF
NPKTLIESVCSRVLKEFEKGEILDKYGVYQLFKDYYNEVLQDDWFLLSFNGFRSAKELRKLTPLKDKNKKANYLEEPDFV
IQKTYYKSDLIPKHLIKQRFFEKETKELEELENALNEKEALLDEFIEEHSNEEGLFYELKINESVLKKELKNATDSEDKK
ILKTALELLEAKNKALKIKNKAYEELELKAFHQYEKLEINEIKDLIIKDKWLNSLKNALENKIQKRINAFISALNGIIQT
YSNSLLELDKEVKESESKVLEHLKDLGIVV

Sequences:

>Translated_670_residues
MRHFASESGKSKGQFYTPSEVSLLLSLLLGIDENTRQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCK
MNMILHNSADADIAKGGSSTLSNPLFTTENGMLKTFDYVVANPPFSLKNWTDGLSIDPKSKQVINDHFNRFEDGTPPEKN
GDFAFLLHIIKSLKNTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGVIGLAPNLFYGTSIPACVIVLDKKNARARKG
VFVIDASKDFKKDGNKNRLREQDVQKMIDTFNALKEIPYYSKMVSLEEISANDYNLNIPRYIAAKQESEKDLFALINSPS
YLPKNEINLYAPYFRVFKELKNTLFKKSDKEGYYALKTECENIKDYITQSSEFQAFHASVLSAFDRLDLFETFEHLEPGF
NPKTLIESVCSRVLKEFEKGEILDKYGVYQLFKDYYNEVLQDDWFLLSFNGFRSAKELRKLTPLKDKNKKANYLEEPDFV
IQKTYYKSDLIPKHLIKQRFFEKETKELEELENALNEKEALLDEFIEEHSNEEGLFYELKINESVLKKELKNATDSEDKK
ILKTALELLEAKNKALKIKNKAYEELELKAFHQYEKLEINEIKDLIIKDKWLNSLKNALENKIQKRINAFISALNGIIQT
YSNSLLELDKEVKESESKVLEHLKDLGIVV
>Mature_670_residues
MRHFASESGKSKGQFYTPSEVSLLLSLLLGIDENTRQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCK
MNMILHNSADADIAKGGSSTLSNPLFTTENGMLKTFDYVVANPPFSLKNWTDGLSIDPKSKQVINDHFNRFEDGTPPEKN
GDFAFLLHIIKSLKNTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGVIGLAPNLFYGTSIPACVIVLDKKNARARKG
VFVIDASKDFKKDGNKNRLREQDVQKMIDTFNALKEIPYYSKMVSLEEISANDYNLNIPRYIAAKQESEKDLFALINSPS
YLPKNEINLYAPYFRVFKELKNTLFKKSDKEGYYALKTECENIKDYITQSSEFQAFHASVLSAFDRLDLFETFEHLEPGF
NPKTLIESVCSRVLKEFEKGEILDKYGVYQLFKDYYNEVLQDDWFLLSFNGFRSAKELRKLTPLKDKNKKANYLEEPDFV
IQKTYYKSDLIPKHLIKQRFFEKETKELEELENALNEKEALLDEFIEEHSNEEGLFYELKINESVLKKELKNATDSEDKK
ILKTALELLEAKNKALKIKNKAYEELELKAFHQYEKLEINEIKDLIIKDKWLNSLKNALENKIQKRINAFISALNGIIQT
YSNSLLELDKEVKESESKVLEHLKDLGIVV

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=245, Percent_Identity=25.3061224489796, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 76499; Mature: 76499

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFASESGKSKGQFYTPSEVSLLLSLLLGIDENTRQDKSIYDPTCGSGSLLLKASSLAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCC
KNGLTIYGQEKDISTTALCKMNMILHNSADADIAKGGSSTLSNPLFTTENGMLKTFDYVV
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCHHCCCCEECCCCCEEHHHHHE
ANPPFSLKNWTDGLSIDPKSKQVINDHFNRFEDGTPPEKNGDFAFLLHIIKSLKNTGKGA
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
VILPHGVLFRGNAEGVIRKNLLTKGYIKGVIGLAPNLFYGTSIPACVIVLDKKNARARKG
EEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC
VFVIDASKDFKKDGNKNRLREQDVQKMIDTFNALKEIPYYSKMVSLEEISANDYNLNIPR
EEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCH
YIAAKQESEKDLFALINSPSYLPKNEINLYAPYFRVFKELKNTLFKKSDKEGYYALKTEC
HHHCCCCCCCHHHHEECCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
ENIKDYITQSSEFQAFHASVLSAFDRLDLFETFEHLEPGFNPKTLIESVCSRVLKEFEKG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
EILDKYGVYQLFKDYYNEVLQDDWFLLSFNGFRSAKELRKLTPLKDKNKKANYLEEPDFV
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
IQKTYYKSDLIPKHLIKQRFFEKETKELEELENALNEKEALLDEFIEEHSNEEGLFYELK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
INESVLKKELKNATDSEDKKILKTALELLEAKNKALKIKNKAYEELELKAFHQYEKLEIN
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHH
EIKDLIIKDKWLNSLKNALENKIQKRINAFISALNGIIQTYSNSLLELDKEVKESESKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLKDLGIVV
HHHHHCCCCC
>Mature Secondary Structure
MRHFASESGKSKGQFYTPSEVSLLLSLLLGIDENTRQDKSIYDPTCGSGSLLLKASSLAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCC
KNGLTIYGQEKDISTTALCKMNMILHNSADADIAKGGSSTLSNPLFTTENGMLKTFDYVV
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCHHCCCCEECCCCCEEHHHHHE
ANPPFSLKNWTDGLSIDPKSKQVINDHFNRFEDGTPPEKNGDFAFLLHIIKSLKNTGKGA
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
VILPHGVLFRGNAEGVIRKNLLTKGYIKGVIGLAPNLFYGTSIPACVIVLDKKNARARKG
EEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC
VFVIDASKDFKKDGNKNRLREQDVQKMIDTFNALKEIPYYSKMVSLEEISANDYNLNIPR
EEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCH
YIAAKQESEKDLFALINSPSYLPKNEINLYAPYFRVFKELKNTLFKKSDKEGYYALKTEC
HHHCCCCCCCHHHHEECCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
ENIKDYITQSSEFQAFHASVLSAFDRLDLFETFEHLEPGFNPKTLIESVCSRVLKEFEKG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
EILDKYGVYQLFKDYYNEVLQDDWFLLSFNGFRSAKELRKLTPLKDKNKKANYLEEPDFV
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
IQKTYYKSDLIPKHLIKQRFFEKETKELEELENALNEKEALLDEFIEEHSNEEGLFYELK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
INESVLKKELKNATDSEDKKILKTALELLEAKNKALKIKNKAYEELELKAFHQYEKLEIN
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHH
EIKDLIIKDKWLNSLKNALENKIQKRINAFISALNGIIQTYSNSLLELDKEVKESESKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHLKDLGIVV
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]