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The map label for this gene is 108563827

Identifier: 108563827

GI number: 108563827

Start: 1458409

End: 1458762

Strand: Reverse

Name: 108563827

Synonym: HPAG1_1402

Alternate gene names: NA

Gene position: 1458762-1458409 (Counterclockwise)

Preceding gene: 108563829

Following gene: 108563826

Centisome position: 91.38

GC content: 35.59

Gene sequence:

>354_bases
ATGAAAGCTAAACAAGGCGTTCATATCCATAACTTGGTGTTTGAAACGATTTTAGGGATTTTAGAGTTTGAACGCTTAAA
ACCCCAAAAAATAAGCGTAGATTTGGATCTTTTCTACACGGAATTACCCAATAAGGCTTATTTAGACTACATAAAAATCC
AAGAGCTTATCCAAAAGATGATGCAAGAAAAACAATACCTTCTCATTGAAGACGCTCTGAAAGATTTAAGCCATGCTTTA
AAAACGCGCTATAGTGGAATCTCTGAGCTTTATTTGAAAATCAGCAAGTTAGAAATTTCTCCCAATTCTCAAGTGGGAGC
GAGCGTGAAAATCTGCTATGAAAACGATCTTTAG

Upstream 100 bases:

>100_bases
TCGACACGCAAACGCCGATGGTGCTTATTTTTATTTTCACCCTTATCAAGCATGCGGGCAATATTTTTAATTTGTTAGCC
GGTAAGGAAAAGAAAGTCTT

Downstream 100 bases:

>100_bases
CCTCTTTTTCCTTCTTATTGTTTTAAAAGCGCACCCCATAAACCCTTTATTAGAGCCGCTATATTTCCCCAGTTACGCGC
AATTTTTAAATTTAGAACCT

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MKAKQGVHIHNLVFETILGILEFERLKPQKISVDLDLFYTELPNKAYLDYIKIQELIQKMMQEKQYLLIEDALKDLSHAL
KTRYSGISELYLKISKLEISPNSQVGASVKICYENDL

Sequences:

>Translated_117_residues
MKAKQGVHIHNLVFETILGILEFERLKPQKISVDLDLFYTELPNKAYLDYIKIQELIQKMMQEKQYLLIEDALKDLSHAL
KTRYSGISELYLKISKLEISPNSQVGASVKICYENDL
>Mature_117_residues
MKAKQGVHIHNLVFETILGILEFERLKPQKISVDLDLFYTELPNKAYLDYIKIQELIQKMMQEKQYLLIEDALKDLSHAL
KTRYSGISELYLKISKLEISPNSQVGASVKICYENDL

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 13589; Mature: 13589

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKQGVHIHNLVFETILGILEFERLKPQKISVDLDLFYTELPNKAYLDYIKIQELIQKM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHEEHEECCCCHHHHHHHHHHHHHHHH
MQEKQYLLIEDALKDLSHALKTRYSGISELYLKISKLEISPNSQVGASVKICYENDL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MKAKQGVHIHNLVFETILGILEFERLKPQKISVDLDLFYTELPNKAYLDYIKIQELIQKM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHEEHEECCCCHHHHHHHHHHHHHHHH
MQEKQYLLIEDALKDLSHALKTRYSGISELYLKISKLEISPNSQVGASVKICYENDL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA