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The map label for this gene is selA [H]

Identifier: 108563824

GI number: 108563824

Start: 1453968

End: 1455128

Strand: Reverse

Name: selA [H]

Synonym: HPAG1_1399

Alternate gene names: 108563824

Gene position: 1455128-1453968 (Counterclockwise)

Preceding gene: 108563825

Following gene: 108563823

Centisome position: 91.15

GC content: 37.64

Gene sequence:

>1161_bases
ATGGCTAAAGAAACGCTTGAAATAACCCCGGATCTTTTGAAAAACCCTTATCAAAAAATCATCAATGCGAGCGCGAGCGT
TTTTGATGAAAAGCATGGGCGATCGTTTTTTAGCCCGCAATTTTATGAAACAATTGAACCTTATTTAAAAGAAGTTTTAA
CCCATCCCATTGATTTAGAATGCGATTTAAACACCGCTAAAAAAAAGAACCGCTTAACCCCTTTAAAACAACTCTTTAAG
GCGTGTTTTAACACCGAAGAAATTTTGATTGTGAATAACAACACCAGCGCGATATTCCTCATCGCTAACGCTTTAGCGCA
AGAAAAAGAAATCGTTGTTTCTTATGGCGAATTAGTGGGGGGGGATTTTAACCTTAAAGATATTTTATTAAATAGTGGGG
CTAGGCTGCATTTAGTGGGAAATATTAATCGCGCTTATTTAAGGGATTACCGCTTGGCCTTGAATGAAAACAGCAAAATG
CTCTTTAAAACCCACAACCCCCATTTTAAAAAAGACACGCCCTTTAAAGATTTACAAGCTCTGGCTAAAGAGCATGATCT
CATTGATTATTACAATTTAGGGGATGTGGATTTGTTAAACAGGGCGACTTTAGAAGAAATTTTAGCTCTCAAACCATCGC
TTTTAAGCTTTAGCACGGATAAATTCTTTAACAGCGCGCAAGCGGGCATTATTATGGGGCAAAAAGAACGGGTTGGAATA
TTAAAAAACCACCCCCTTTATAGAGCCTTGAGGGTGGGTAAAATCACGCTCACCTTGCTTTTTTGCAGCCTAAAAGCATG
GGTCAATCATCAAGAAGAAATTGCAATCCATGCGTTATTGAACCAAACTAAAGACGCGTTATTGCAAAAAGCCCTCAAAC
TCTACGCCCTTTTAAAGCCTTTAGAATTGAATGTGAGCATAGCCTCTAGCTTTTCTAAAATAGGGAATTTGCCCGATAGA
GAATTGGAATCCTTTTGCGTGAAAATCCAGTCCAAAAACACCCGCGCTTTAAATAGTGAGAAACTTTATTTAAAGCTTTT
TCAAAAAGGCATTATCGCAAGAATTTCATGCGAATTTGTGTGCTTTGAAGTCTTTAGCTTGAATGAAAAAGATTTGGAAA
AAATCGCTCTGGTTTTAAAAGAAATCCTTAACAAGGCCTAA

Upstream 100 bases:

>100_bases
TTAAGGATTTTAAAAAAGTAGTTTTATCAAAAATTTAGCGAGTTTAGTTTAAGATAACGCTTTATTTTAACTCAAAAAAG
GAATCAAACGCGCTTCCACT

Downstream 100 bases:

>100_bases
AAATTCGCTATAATAAAATTTCTTTTAAACGTGCCATATCCCCCACAAAACGCTAGAGAATGATAGAAAACGATAGAACA
TCAATTTAAAGGAACTTAAG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MAKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKQLFK
ACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKM
LFKTHNPHFKKDTPFKDLQALAKEHDLIDYYNLGDVDLLNRATLEEILALKPSLLSFSTDKFFNSAQAGIIMGQKERVGI
LKNHPLYRALRVGKITLTLLFCSLKAWVNHQEEIAIHALLNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDR
ELESFCVKIQSKNTRALNSEKLYLKLFQKGIIARISCEFVCFEVFSLNEKDLEKIALVLKEILNKA

Sequences:

>Translated_386_residues
MAKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKQLFK
ACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKM
LFKTHNPHFKKDTPFKDLQALAKEHDLIDYYNLGDVDLLNRATLEEILALKPSLLSFSTDKFFNSAQAGIIMGQKERVGI
LKNHPLYRALRVGKITLTLLFCSLKAWVNHQEEIAIHALLNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDR
ELESFCVKIQSKNTRALNSEKLYLKLFQKGIIARISCEFVCFEVFSLNEKDLEKIALVLKEILNKA
>Mature_385_residues
AKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKQLFKA
CFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKML
FKTHNPHFKKDTPFKDLQALAKEHDLIDYYNLGDVDLLNRATLEEILALKPSLLSFSTDKFFNSAQAGIIMGQKERVGIL
KNHPLYRALRVGKITLTLLFCSLKAWVNHQEEIAIHALLNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDRE
LESFCVKIQSKNTRALNSEKLYLKLFQKGIIARISCEFVCFEVFSLNEKDLEKIALVLKEILNKA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=367, Percent_Identity=32.425068119891, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 43886; Mature: 43754

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYETIEPYLKEVLTHPIDLE
CCCCCCCCCHHHHHCHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
CDLNTAKKKNRLTPLKQLFKACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVG
ECCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHEEHHHHHC
GDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKMLFKTHNPHFKKDTPFKDLQA
CCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHH
LAKEHDLIDYYNLGDVDLLNRATLEEILALKPSLLSFSTDKFFNSAQAGIIMGQKERVGI
HHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCCEEECCHHCCCH
LKNHPLYRALRVGKITLTLLFCSLKAWVNHQEEIAIHALLNQTKDALLQKALKLYALLKP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LELNVSIASSFSKIGNLPDRELESFCVKIQSKNTRALNSEKLYLKLFQKGIIARISCEFV
CEECHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHEEEEHHEE
CFEVFSLNEKDLEKIALVLKEILNKA
EEHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSPQFYETIEPYLKEVLTHPIDLE
CCCCCCCCHHHHHCHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
CDLNTAKKKNRLTPLKQLFKACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVG
ECCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHEEHHHHHC
GDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKMLFKTHNPHFKKDTPFKDLQA
CCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHH
LAKEHDLIDYYNLGDVDLLNRATLEEILALKPSLLSFSTDKFFNSAQAGIIMGQKERVGI
HHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCCEEECCHHCCCH
LKNHPLYRALRVGKITLTLLFCSLKAWVNHQEEIAIHALLNQTKDALLQKALKLYALLKP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LELNVSIASSFSKIGNLPDRELESFCVKIQSKNTRALNSEKLYLKLFQKGIIARISCEFV
CEECHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHEEEEHHEE
CFEVFSLNEKDLEKIALVLKEILNKA
EEHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA