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The map label for this gene is oxaA [H]

Identifier: 108563801

GI number: 108563801

Start: 1424692

End: 1426338

Strand: Direct

Name: oxaA [H]

Synonym: HPAG1_1376

Alternate gene names: 108563801

Gene position: 1424692-1426338 (Clockwise)

Preceding gene: 108563800

Following gene: 108563802

Centisome position: 89.25

GC content: 40.01

Gene sequence:

>1647_bases
ATGGATAAAAACAACAATAATAATCTCCGCTTGATTTTAGCGATCGCTCTGTCTTTCTTATTTATCGCTATTTACAGCTA
TTTTTTCCAAAAACCAAACAAAACAACAACCCAAACCACAAAGCAAGAAACAACCAACAACCATACAGCAACAAGTCCTA
ACGCGCCCAACGCCCAACATTTTAGCGTTACTCAAACCATCCCCCAAGAGAATTTGTTAAGCACGATTTCTTTTGAGCAT
GCCAGGATTGAAATTGATTCTTTAGGGCGCATCAAACAGGTTTATCTCAAGGATAAAAAGTATCTAACCCCTAAACAAAA
GGGCTTTTTAGAGCATGTGGGCCATCTTTTTAGCCCCAAAGCTAACCCACAAAACCTCCTAAAAGAACTCCCCCTTTTAG
CAGCCGATAAACTCAAGCCTTTAGAAGTGCGTTTTTTAGACCCTACGCTCAATAACAAAGCGTTCAACACCCCTTATAGC
GCTTCAAAAACCACTCTTGGGCCTAATGAACAGCTTGTTTTAACCCAAGATTTAGGCACTCTTACCATCATTAAAACCCT
GACTTTTTATGATGATTTGCATTATGATTTGCAAATCGCCTTCAAATCGCCCAACAATATTATCCCTAGCTATGTGATCA
CCAATGGTTACAGGCCGGTGGCTGATTTGGACAGCTACACCTTTTCAGGCGTGCTTTTAGAAAACAACGACAAAAAAATT
GAAAAAATTGAAGATAAAGACGCTAAAGAAATCAAACGCTTTTCTAACACCCTCTTTTTATCCAGCGTGGATAGGTATTT
CACCACCTTGCTTTTCACTAAAGATCCTCAAGGTTTTGAAGCCTTAATCGATTCAGAAATCGGCACTAAAAACCCCTTAG
GGTTCATTTCCCTTAAAAATGAAGCGAATTTGCATGGCTATATTGGCCCTAAGGATTACCGCTCTTTGAAAGCGATTTCA
CCCATGCTCACTGATGTGATAGAGTATGGCTTGATCACTTTCTTTGCTAAAGGCGTGTTTGTTTTACTGGATTATTTGTA
TCAATTTGTGGGCAATTGGGGTTGGGCTATCATTTTTTTAACGATTATCGTGCGCCTAATCCTTTACCCCTTAAGCTATA
AAGGCATGGTGAGCATGCAAAAGCTCAAGGAATTATCCCCTAAAATGAAAGAGCTCCAAGAAAAATACAAGGGCGAACCC
CAAAAATTGCAAGCCCACATGATGCAGCTTTACAAAAAACATGGGGCTAACCCACTAGGGGGTTGTCTGCCCTTAATCTT
ACAAATCCCGGTGTTTTTTGCGATTTATAGAGTGCTTTATAACGCTGTGGAATTGAAAAGCTCAGAGTGGATTCTATGGA
TTCATGATTTATCCATCATGGATCCGTATTTTATTTTGCCGCTTCTTATGGGAGCGTCTATGTATTGGCACCAAAGCGTT
ACGCCAAACACCATGACCGATCCCATGCAAGCGAAGATTTTTAAACTCTTACCCCTATTATTCACAATCTTTTTAATCAC
TTTCCCTGCAGGGTTAGTCTTGTATTGGACCACGAACAACATCCTTTCGGTGTTGCAACAACTCATCATCAATAAAGTCT
TAGAGAACAAAAAACGCATGCACGCGCAAAACAAAAAGGAACATTGA

Upstream 100 bases:

>100_bases
CTCATAAAGATTTTAATCGCAATTTTAAAACCATTACTTTTTGGCTCGTTCCTACTACAAAAAGCCGCACAACTTACTAC
ATCATTAAGGTTTGATCACA

Downstream 100 bases:

>100_bases
TGCAAAATTTTATTGAAATCAAAGCCAAAACCTTAGAAGAAGCCCTCATTCAAGCTTCTATCGCTTTGAATTGCCCCATT
ATTAATTTGCAATACGAAGT

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MDKNNNNNLRLILAIALSFLFIAIYSYFFQKPNKTTTQTTKQETTNNHTATSPNAPNAQHFSVTQTIPQENLLSTISFEH
ARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVGHLFSPKANPQNLLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYS
ASKTTLGPNEQLVLTQDLGTLTIIKTLTFYDDLHYDLQIAFKSPNNIIPSYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIIFLTIIVRLILYPLSYKGMVSMQKLKELSPKMKELQEKYKGEP
QKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSV
TPNTMTDPMQAKIFKLLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKEH

Sequences:

>Translated_548_residues
MDKNNNNNLRLILAIALSFLFIAIYSYFFQKPNKTTTQTTKQETTNNHTATSPNAPNAQHFSVTQTIPQENLLSTISFEH
ARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVGHLFSPKANPQNLLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYS
ASKTTLGPNEQLVLTQDLGTLTIIKTLTFYDDLHYDLQIAFKSPNNIIPSYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIIFLTIIVRLILYPLSYKGMVSMQKLKELSPKMKELQEKYKGEP
QKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSV
TPNTMTDPMQAKIFKLLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKEH
>Mature_548_residues
MDKNNNNNLRLILAIALSFLFIAIYSYFFQKPNKTTTQTTKQETTNNHTATSPNAPNAQHFSVTQTIPQENLLSTISFEH
ARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVGHLFSPKANPQNLLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYS
ASKTTLGPNEQLVLTQDLGTLTIIKTLTFYDDLHYDLQIAFKSPNNIIPSYVITNGYRPVADLDSYTFSGVLLENNDKKI
EKIEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAIS
PMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIIFLTIIVRLILYPLSYKGMVSMQKLKELSPKMKELQEKYKGEP
QKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSV
TPNTMTDPMQAKIFKLLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKEH

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=336, Percent_Identity=36.6071428571429, Blast_Score=243, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24662345, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356443, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 62811; Mature: 62811

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNNNNNLRLILAIALSFLFIAIYSYFFQKPNKTTTQTTKQETTNNHTATSPNAPNAQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCE
FSVTQTIPQENLLSTISFEHARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVGHLFSPK
EEHHHHCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
ANPQNLLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLVLTQDLGT
CCHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCH
LTIIKTLTFYDDLHYDLQIAFKSPNNIIPSYVITNGYRPVADLDSYTFSGVLLENNDKKI
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHH
EKIEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECC
EANLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIIFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIIVRLILYPLSYKGMVSMQKLKELSPKMKELQEKYKGEPQKLQAHMMQLYKKHGANPLG
HHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
GCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHCCCCC
TPNTMTDPMQAKIFKLLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
HAQNKKEH
HHCCCCCC
>Mature Secondary Structure
MDKNNNNNLRLILAIALSFLFIAIYSYFFQKPNKTTTQTTKQETTNNHTATSPNAPNAQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCE
FSVTQTIPQENLLSTISFEHARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVGHLFSPK
EEHHHHCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
ANPQNLLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLVLTQDLGT
CCHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCH
LTIIKTLTFYDDLHYDLQIAFKSPNNIIPSYVITNGYRPVADLDSYTFSGVLLENNDKKI
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHH
EKIEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECC
EANLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIIFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TIIVRLILYPLSYKGMVSMQKLKELSPKMKELQEKYKGEPQKLQAHMMQLYKKHGANPLG
HHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
GCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHCCCCC
TPNTMTDPMQAKIFKLLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
HAQNKKEH
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]