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The map label for this gene is rnpA

Identifier: 108563799

GI number: 108563799

Start: 1423857

End: 1424357

Strand: Direct

Name: rnpA

Synonym: HPAG1_1374

Alternate gene names: 108563799

Gene position: 1423857-1424357 (Clockwise)

Preceding gene: 108563798

Following gene: 108563800

Centisome position: 89.19

GC content: 35.93

Gene sequence:

>501_bases
ATGCCAGACGAGCTAAGGGCAGAAAAAAGCTTTCAGTCTAAACCCTATGACTCTTTAAAAAACAAGAGTGAGTTTGATAG
GGTTTATCAAAAGGGTTTCAAAAAACATAACCTTTTTTTTTCGCTCTTTGTTTTGGATTTATCAAAAGAGCCACCAAAAG
GAAAAGAAGGCTTTAAAGATCCGCTCTCTTGTAGGCTTAAAGACAAAAAAACACTTTATTTATTAGGCTTAAGCGTGTCC
AAAAAAGTCGGCAATGCCGTGAAACGAAATCTCATCAAACGCCGTTTGCGTTCGCTTACATTAAAGCATGCCGCTCTTTG
TCAAGGGCTTGCTTTGGTGTTTGTGCCTAGAAGCGATTGTTACCATTTGGATTTTTGGGCTTTAGAAAAACATTTTTTAG
AAATGCTAACTTCCATTAAAAACTATATTGAACAAAGCCTTAAAAGACTTGAAAAAAGGAATAACTCATACCTATGCGAA
ACAATAAAACGCCTTTTTTGA

Upstream 100 bases:

>100_bases
TTTTAAATGAAACGCACTTACCAACCACACAACACACCAAGAAAGCGAACCCATGGCTTTCTTGTGAGAATGAAAACCAA
AAACGGGCGCAAGGTGATCA

Downstream 100 bases:

>100_bases
GCGCGATTTTTACGGCATCAATTAGGGGTTACCAACGCTTTTTTTCGGCTTTCACCCCTTCAAGCTGCCGGTTTTACCCC
ACTTGCTCTAACTACGCTCT

Product: ribonuclease P, protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MPDELRAEKSFQSKPYDSLKNKSEFDRVYQKGFKKHNLFFSLFVLDLSKEPPKGKEGFKDPLSCRLKDKKTLYLLGLSVS
KKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYIEQSLKRLEKRNNSYLCE
TIKRLF

Sequences:

>Translated_166_residues
MPDELRAEKSFQSKPYDSLKNKSEFDRVYQKGFKKHNLFFSLFVLDLSKEPPKGKEGFKDPLSCRLKDKKTLYLLGLSVS
KKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYIEQSLKRLEKRNNSYLCE
TIKRLF
>Mature_165_residues
PDELRAEKSFQSKPYDSLKNKSEFDRVYQKGFKKHNLFFSLFVLDLSKEPPKGKEGFKDPLSCRLKDKKTLYLLGLSVSK
KVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYIEQSLKRLEKRNNSYLCET
IKRLF

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_HELPH (Q1CRI1)

Other databases:

- EMBL:   CP000241
- RefSeq:   YP_628115.1
- ProteinModelPortal:   Q1CRI1
- SMR:   Q1CRI1
- STRING:   Q1CRI1
- GeneID:   4098045
- GenomeReviews:   CP000241_GR
- KEGG:   hpa:HPAG1_1374
- eggNOG:   COG0594
- HOGENOM:   HBG501564
- OMA:   KHFLEML
- ProtClustDB:   CLSK496496
- BioCyc:   HPYL357544:HPAG1_1374-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 19520; Mature: 19389

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDELRAEKSFQSKPYDSLKNKSEFDRVYQKGFKKHNLFFSLFVLDLSKEPPKGKEGFKD
CCCHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PLSCRLKDKKTLYLLGLSVSKKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDC
CHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCC
YHLDFWALEKHFLEMLTSIKNYIEQSLKRLEKRNNSYLCETIKRLF
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
>Mature Secondary Structure 
PDELRAEKSFQSKPYDSLKNKSEFDRVYQKGFKKHNLFFSLFVLDLSKEPPKGKEGFKD
CCHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PLSCRLKDKKTLYLLGLSVSKKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDC
CHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCC
YHLDFWALEKHFLEMLTSIKNYIEQSLKRLEKRNNSYLCETIKRLF
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA